Chii chinonzi Imatinib: Zvayinoshandiswa, Madosi, Mativi eMuviri, nezvimwe zvakawanda

Imatinib mushonga wekenza unovavarira, unoshanda nekudzivisa mapurotini akati wandei anobatsira maseru ekenza kukura nekuzviparadzanisa. Inonyanya kushandiswa kurapa marudzi akati wandei ekenza yeropa uye mamwe matumbu asingawanzoitiki, ichipa tariro kuvarwere vangave vasina sarudzo dzekurapa dzinoshanda kare.

Mushonga uyu unomiririra budiriro mukurapa kenza nekuti unovavarira maseru ekenza zvakanyanya kupfuura chemotherapy yechinyakare. Panzvimbo pekurwisa maseru ese anokurumidza kupatsanurwa, imatinib inotarisa pamapurotini asina kujairika anotyaira kenza yakati wandei kukura.

Chii chinonzi Imatinib?

Imatinib imhando yemushonga wekenza unonzi tyrosine kinase inhibitor. Iyo ndeyemukirasi yemishonga inozivikanwa semishonga yekurapa inotarirwa, zvinoreva kuti inonyanya kutarisisa mapurotini akati wandei anobatanidzwa mukukura kweseru rekenza.

Mushonga unoshanda nekudzivisa ma enzymes anonzi tyrosine kinases anotumira zviratidzo zvichiti maseru ekenza azviparadzanise. Funga nezvema enzymes aya semaswiti anobatidza kukura kwekenza - imatinib inonyanya kupidigura maswiti iwayo ku

Chiremba wako angangokurairawo imatinib kune zvimwe zvirwere zvisingawanzoitika, kusanganisira mamwe marudzi eacute lymphoblastic leukemia (ALL) uye mamwe matambudziko eropa asingawanzoitika. Kushandiswa uku kunoenderana nemamaki akasiyana e genetic ayo maseru ako ekenza anotakura.

Imatinib Inoshanda Sei?

Imatinib inoshanda nekunangana neprotein isina kujairika inonzi BCR-ABL inowanikwa mumaseru mazhinji eCML. Iyi protein inoita se switch isina kukodzera inogara yakabatidzwa, ichigara ichiudza maseru ekenza kuti akure uye aparadzane.

Paunotora imatinib, inosungirwa kune iyi protein isina kujairika uye inovharisa chiitiko chayo. Izvi zvinomisa maseru ekenza kubva pakugamuchira zviratidzo zvavanoda kuti vazhinjike zvisina kudzora.

Mishonga inoonekwa seyakasimba zvine mwero maererano nekurapa kenza. Kunyange zvazvo ichiwanzotambirwa zviri nani kupfuura chemotherapy yechinyakare, ichiri mushonga une simba unoda kutariswa zvakanyatsonaka nechikwata chako chehutano.

Kune tuma tumor dzeGIST, imatinib inoshanda nekudzivisa imwe protein inonzi KIT, iyo inobatsira tuma tumor idzi kukura. Nekudzivisa iyi protein, mushonga unogona kubatsira kuderedza tuma tumor kana kuvadzivisa kukura zvakakura.

Ndingatora Sei Imatinib?

Tora imatinib sezvinorairwa nachiremba wako, kazhinji kamwe kana kaviri pazuva uine chikafu uye girazi guru remvura. Kuitora nechikafu kunobatsira kuderedza dumbu, iyo imwe yemigumisiro yakajairika.

Medza mahwendefa ese - usapwanye, kuputsa, kana kuatsenga. Kana uine dambudziko rekumedza mahwendefa, taura nachiremba wako nezve sarudzo dzakaita sekunyungudutsa mumvura kana muto weapuro.

Edza kutora mushonga wako panguva imwechete zuva rega rega kuti ikubatsire kuyeuka uye kuchengetedza mazinga akagadzikana mumuviri wako. Vanhu vazhinji vanoona zvichibatsira kutora imatinib nekudya kwemangwanani kana kwemanheru.

Mushure meizvozvo, dzivisa magrapefruit nemuto wemagrapefruit paunenge uchitora imatinib, nekuti zvinogona kukanganisa nzira iyo muviri wako unogadzirisa mushonga. Kukanganisa uku kunogona kuita kuti mushonga usashande zvakanaka kana kuwedzera mhedzisiro.

Ndingatora Imatinib Kwenguva Yakareba Sei?

Vanhu vazhinji vane CML vanoda kutora imatinib kwenguva refu, kazhinji kwemakore mazhinji kana kusvika pakusingaperi. Mushonga unoshanda chero ukaramba uchiutora, asi kuumisa kazhinji kunobvumira kenza kuti idzoke.

Chiremba wako achatarisa mhinduro yako kumushonga kuburikidza nemiedzo yeropa yenguva dzose nemimwe miedzo. Miedzo iyi inobatsira kuziva kuti mushonga uri kushanda sei uye kana paine zvigadziriso zvinodiwa.

Kune varwere veGIST, nguva yekurapa inoenderana nezvinhu zvakasiyana-siyana, kusanganisira kuti bundu rinopindura sei uye kana wakavhiwa. Vamwe vanhu vanogona kuiita kwenguva yakati, nepo vamwe vachida kurapwa kwenguva refu.

Usambomira kutora imatinib usina kukurukura nachiremba wako kutanga. Kumisa kamwe kamwe kunogona kutungamirira kukufambira mberi kwekenza nekukurumidza, kunyangwe iwe uchinzwa zvakanaka.

Ndezvipi Zvakaipa ZveImatinib?

Semishonga yese, imatinib inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Mazhinji emhedzisiro anogoneka uye anowanzoita nani sezvo muviri wako uchigadzirisa kumushonga.

Mhedzisiro inowanzoitika yaungasangana nayo inosanganisira kusvotwa, manyoka, mhasuru dzemhasuru, uye kuchengetwa kwemvura kunogona kukonzera kuzvimba mumakumbo ako, zvitsitsinho, kana kutenderedza maziso ako. Zviratidzo izvi zvinowanzoita zvinyoro kusvika pakati nepakati uye zvinowanzoita nani nekufamba kwenguva.

Heano mhedzisiro inowanzoitika iyo varwere vanoshuma:

• Kusvotwa nekutsvuka
• Manyoka kana zvigaro zvakasununguka
• Mhasuru dzemhasuru, kunyanya mumakumbo
• Kuneta nekupera simba
• Kutemwa nemusoro
• Kuputika kweganda kana kukwenya
• Kuchengetwa kwemvura kunokonzera kuzvimba
• Kuwedzera uremu nekuda kwekuchengetwa kwemvura

Zvizhinji zvezvinhu izvi zvinogona kugadziriswa nekutarisirwa, kuchinja kudya, kana mishonga yekuwedzera kana zvichidikanwa. Chikwata chako chehutano chinogona kupa nzira dzekubatsira kuderedza mhedzisiro iyi.

Zvimwe zvisingawanzoitiki asi zvakanyanya kukomba zvinoda kutariswa kwekurapa nekukurumidza. Izvi zvinosanganisira kuchengetwa kwemvura kwakanyanya kunokanganisa kufema kwako, zviratidzo zvematambudziko echiropa sekusviba kweganda kana maziso, kubuda ropa kusingaite kana kuputika, uye kurwadziwa kwakanyanya mudumbu.

Zvisingawanzoitiki asi zvakanyanya kukomba zvinogona kusanganisira matambudziko emoyo, kukuvadzwa kwakanyanya kwechiropa, uye kudonha kukuru muhuwandu hwemasero eropa ayo anowedzera njodzi yekutapukirwa. Chiremba wako achatarisa izvi kuburikidza nekuongororwa kweropa nguva dzose uye kuongororwa.

Ndiani Asingafaniri Kutora Imatinib?

Haufaniri kutora imatinib kana uine allergic kune iyo kana chero zvinosanganiswa zvayo. Udza chiremba wako nezve chero kare allergic reactions kumishonga, kunyanya kana wakambove neakanyanya reactions.

Vanhu vane chirwere chechiropa chakanyanya vangangoda kugadzirisa dose kana vangave vasiri vakakodzera candidates for imatinib kurapwa. Chiremba wako achaongorora basa rechiropa chako usati watanga kurapwa uye achachitarisa nguva dzose.

Kana iwe uri nepamuviri kana kuronga kuva nepamuviri, taura izvi nachiremba wako nekukurumidza. Imatinib inogona kukuvadza mwana asati aberekwa, saka kudzivirira kubata pamuviri kunoshanda kwakakosha panguva yekurapwa kune varume nevakadzi.

Vanamai vanoyamwisa havafaniri kutora imatinib, sezvo mushonga unogona kupinda mumukaka wemazamu uye unogona kukuvadza mwana anoyamwisa. Nzira dzekudyisa dzimwe dzinofanirwa kutaurwa nechikwata chako chehutano.

Imatinib Mazita eBrand

Imatinib inonyanya kuzivikanwa nezita rebrand Gleevec muUnited States uye Glivec mune dzimwe nyika zhinji. Aya ndiwo mazita ekutanga ebrand akagadzirwa nekambani yemishonga Novartis.

Mhando dzakajairika dzeimatinib zvino dziripo uye dzinongonzi "imatinib" vachiteverwa nezita remugadziri. Mhando idzi dzakajairika dzine chinhu chimwe chete chinoshanda uye dzinoshanda nenzira imwechete semushonga une zita remhando.

Khemisi yako inogona kutsiva mhando yakajairika kunze kwekunge chiremba wako achikumbira zita remhando. Mhando dzese dziri mbiri dzinoshanda zvakaenzana, kunyangwe vamwe vanhu vachigona kuva nezvavanofarira zvichibva pane zvavakawana nezve mhedzisiro kana kugona kutakura.

Zvimwe Zvingashandiswa Pane Imatinib

Kana imatinib isingashande zvakanaka kwauri kana kukonzera mhedzisiro isingashiviriki, mishonga yakati wandei inowanikwa. Izvi zvinosanganisira mamwe ma tyrosine kinase inhibitors akadai se dasatinib, nilotinib, uye bosutinib yekurapa CML.

Kune varwere vanovandudza kuramba imatinib, mishonga iyi itsva inowanzoita imwe nzira inoshanda. Imwe neimwe ine chimiro chakasiyana che mhedzisiro, saka kuchinja kungabatsira kana uri kusangana nematambudziko chaiwo.

Sarudzo yeimwe nzira inoenderana nezvinhu zvakasiyana siyana zvinosanganisira rudzi rwako rwegomarara, kurapwa kwapfuura, mamwe mamiriro ehutano, uye kuti wakashivirira sei imatinib. Chiremba wako weoncologist achabatsira kuona sarudzo yakanakisa yemamiriro ako ezvinhu.

Vamwe varwere vanogona zvakare kuve vakakodzera kune mamwe marapirwo akadai sekuchinjisa mupfupa wemuzongoza, kunyangwe izvi zvakachengeterwa mamiriro chaiwo uye varwere vadiki.

Imatinib Zviri Nani Pane Zvimwe Zvinhu Zvinorapa CML Here?

Imatinib ndiyo yaive yekutanga kurapwa kwakanangana neCML uye inoramba iri kurapwa kwakanaka kwekutanga kune varwere vazhinji. Iine rekodhi refu yekuchengeteka uye kushanda, ine makore anopfuura makumi maviri eruzivo rwekiriniki.

Mishonga mitsva yakaita se dasatinib uye nilotinib inogona kushanda nekukurumidza mune vamwe varwere uye inogona kushanda kune vanhu vasingapindure zvakanaka kune imatinib. Zvisinei, vanogonawo kuva nemhando dzakasiyana dzemhedzisiro iyo vamwe varwere vanowana ichinetsa.

Mushonga "akanaka" unosiyana kubva kumunhu nemunhu zvichienderana nezvinhu zvakaita se zera, mamwe mamiriro ehutano, kugona kutakura mhedzisiro, uye kuti gomarara rinopindura sei kurapwa. Chiremba wako achafunga zvese izvi paanenge achikurudzira kurapwa.

Varwere vazhinji vanofamba zvakanaka pa imatinib sekurapwa kwavo kwekutanga uye vanoramba vachitora kwemakore vasina chikonzero chekuchinja. Chinhu chakakosha ndechokuwana mushonga unoshanda zvakanyanya kumamiriro ako chaiwo uye mararamiro ako.

Mibvunzo Inowanzo Bvunzwa Nezve Imatinib

Imatinib Yakachengeteka Here Kune Vanhu vane Chirwere Chemoyo?

Imatinib dzimwe nguva inogona kukonzera matambudziko emoyo, kusanganisira kuchengetwa kwemvura kunogona kukuvadza moyo. Kana uine chirwere chemoyo chiripo, chiremba wako achakutarisa zvakanyanya uye anogona kukurudzira bvunzo dzemabasa emoyo pamberi uye panguva yekurapwa.

Vanhu vazhinji vane mamiriro emoyo vanogona kutora imatinib zvakachengeteka, asi vanoda kuongororwa kwakawanda. Chiremba wako wemoyo uye oncologist vachashanda pamwechete kuti vave nechokwadi chekuti kurapwa kwakachengeteka kwauri.

Ndoita Sei Kana Ndikatora Imatinib yakawanda netsaona?

Kana ukatora imatinib yakawanda netsaona kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Usamirire kuti zviratidzo zviuye, sezvo kuwana zano rekurapa nekukurumidza kwakakosha.

Kutora imatinib yakawanda kunogona kuwedzera njodzi yemhedzisiro yakakomba. Chikwata chako chehutano chingada kukutarisa zvakanyanya kana kutora matanho chaiwo ekudzivirira matambudziko.

Ndoita Sei Kana Ndikakanganwa Dose yeImatinib?

Kana ukakanganwa dose uye iri mukati meawa gumi nemaviri yenguva yako yenguva dzose, tora nekukasira paunorangarira. Kana iri pedyo nedose yako inotevera yakarongwa, skip the missed dose uye uenderere mberi nehurongwa hwako hwenguva dzose.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa. Izvi zvinogona kuwedzera njodzi yako yemhedzisiro pasina kupa rubatsiro rwakawedzerwa.

Ndingamira Rini Kutora Imatinib?

Regai kumwa imatinib chete kana chiremba wako akakuudza kuti uite saizvozvo. Kunyangwe ukanzwa zvakanaka zvachose uye bvunzo dzako dzeropa dzichitaridzika dzakajairika, kumisa mushonga usina kutarisirwa nachiremba kunogona kukonzera kudzoka kwekenza.

Vamwe varwere vanogona kukodzera kuenda mukuregererwa kusina kurapwa mushure memakore ekurapa kwakabudirira, asi chisarudzo ichi chinoda kuongororwa zvakanyatsonaka uye kuenderera mberi nekutarisa nechikwata chako chekuchengetedza hutano.

Ndingatora Mamwe Mishonga Ndichiri paImatinib Here?

Mishonga yakawanda inogona kutorwa zvakachengeteka neimatinib, asi mimwe inogona kupindirana uye kuchinja mashandiro ayo. Nguva dzose udza chiremba wako nemupharmacist nezve mishonga yese, zvinowedzera, uye zvigadzirwa zvemiti zvauri kutora.

Mimwe mishonga inowanzo pindirana neimatinib inosanganisira mimwe mishonga yemoyo, mishonga yekubata, uye mamwe maantibayoti. Chikwata chako chekuchengetedza hutano chichaongorora mishonga yako yese kuti ive nechokwadi chekuti zvakachengeteka kutora pamwe chete.