Chii chinonzi Lefamulin: Zvinoshandiswa, Dosages, Side Effects uye Zvimwe

Lefamulin mushonga mutsva weantibiotic unovandudzwa nevachiremba kurapa zvirwere zvakakomba zvebacterial lung infections kana uri muchipatara. Iyo inhengo yechikamu chakakosha chemaantibiotics anonzi pleuromutilins, ayo anoshanda zvakasiyana kubva kune mamwe maantibiotics aunogona kuziva.

Mushonga uyu unopihwa zvakananga muropa rako kuburikidza neIV (intravenous) line. Chikwata chako chehutano chichakuchengeta zvakanyatso chengeta iwe paunogamuchira kurapwa uku kuti uve nechokwadi chekuti iri kushanda nemazvo uye zvakachengeteka.

Chii chinonzi Lefamulin chinoshandiswa?

Lefamulin yakagadzirirwa kunyanya kurapa community-acquired bacterial pneumonia (CABP) muvanhu vakuru. Izvi zvinoreva kuti inorwisa zvirwere zvemapapu zvaungangove wakatora kunze kwechipatara, pane zvirwere zvinomuka panguva yekugara muchipatara.

Chiremba wako angasarudza lefamulin kana mamwe maantibiotics asina kushanda kana kana mabhakitiriya chaiwo ari kukonzera pneumonia yako. Inonyanya kushanda kurwisa mamwe mabhakitiriya akaoma anogona kuramba kune mamwe marapirwo, kusanganisira mamwe marudzi eStreptococcus pneumoniae uye Staphylococcus aureus.

Mushonga uyu wakachengeterwa mamiriro ezvinhu aunoda kugara muchipatara kuti urapwe. Chikwata chako chehutano chichasarudza kana lefamulin iri sarudzo chaiyo zvichienderana nezvirwere zvako uye nhoroondo yekurapa.

Lefamulin inoshanda sei?

Lefamulin inoshanda nekumisa mabhakitiriya kubva pakugadzira mapuroteni avanoda kuti vararame uye vazhinjise. Funga nezvazvo sekukanganisa fekitori yekugadzira mapuroteni emabhakitiriya, iyo inozopedzisira yaita kuti mabhakitiriya anokuvadza afe.

Iyi antibiotic inoonekwa seyakasimba zvine mwero uye inhengo yechikamu chakasiyana chinoshanda zvakasiyana kubva kumapenicillins kana mamwe maantibiotics akajairika. Nekuti ine nzira yakasiyana yekuita, inogona kazhinji kurwisa mabhakitiriya akave achiramba kune mamwe marapirwo.

Mishonga iyi inoshanda sei?

Mishonga iyi inoshanda pamari ribosomu mukati memasero ebhakitiriya, ayo akafanana nemichina midiki inovaka mapuroteni. Kana lefamulin ikavhara michina iyi, bhakitiriya harigone kushanda zvakanaka uye immune system yako inogona kubvisa hutachiona zviri nani.

Ndingatora sei Lefamulin?

Lefamulin inopiwa chete kuburikidza neIV line muchipatara, saka haufanire kunetseka nezvekuitora kumba. Mukoti wako achaiisa zvakananga muropa rako kwemaminitsi angangoita 60 (awa rimwe) mumaawa gumi nemaviri ega ega.

Haufanire kudzivisa chikafu kana zvinwiwa paunenge uchigamuchira mushonga uyu. Muchokwadi, kugara uine mvura yakakwana uye kuchengetedza chikafu chakanaka kunogona kubatsira kutsigira kupora kwako kubva kuhutachiona hwemapapu.

Vashandi vehutano vachakutarisa zvakanyanya panguva yekuiswa kwega kwega. Vachaongorora saiti yako yeIV nguva dzose uye vachatarisa chero zviratidzo zvekuita kana mhedzisiro. Kuiswa zvishoma nezvishoma kunobatsira kuona kuti muviri wako unotsungirira mushonga zvakanaka.

Ndingatora Lefamulin kwenguva yakareba sei?

Vanhu vazhinji vanogamuchira lefamulin kwemazuva anenge 5 kusvika ku7, kunyangwe chiremba wako achaziva nguva chaiyo zvichienderana nekuti uri kupindura sei kurapwa. Vamwe varwere vangada kuishandisa kwemazuva gumi kana hutachiona hwavo huri hunyengeri.

Vashandi vehutano vachatarisa zviratidzo zvako, basa reropa, uye X-rays yechipfuva kuti vaone kuti hutachiona huri kubviswa sei. Vachatarisawo zviratidzo zvekuti mushonga uri kushanda, senge kufema kuri nani, kuderedzwa kwefivha, uye mazinga esimba ari nani.

Kunyangwe ukatanga kunzwa zviri nani mushure memazuva mashoma, zvakakosha kuti upedze nzira yakazara iyo chiremba wako anoraira. Kumisa maantibayoti nekukurumidza kunogona kubvumira bhakitiriya kudzoka uye pamwe kuve nemishonga yekurapa.

Ndezvipi Zvakaipa zveLefamulin?

Kufanana nemishonga yese, lefamulin inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoita izvozvo. Mazhinji emhedzisiro anogoneka uye timu yako yehutano yakagadzirira kukubatsira kuburikidza nekusagadzikana kupi nekupi.

Hezvino zvinowanzoitika zvinogona kuoneka paunenge uchigamuchira lefamulin:

• Kunzwa kusvotwa kana kunzwa kusagadzikana mudumbu rako
• Manyoka kana zvigaro zvakasununguka
• Maitiro panzvimbo yeIV senge kutsvuka, kuzvimba, kana kurwadziwa kudiki
• Kutemwa nemusoro
• Dizziness kana kunzwa lightheaded
• Kuchinja mumiedzo yekushanda kwechiropa (chiremba wako achazvitarisa)

Izvi zvinowanzoitika zvinowanzoita zvinyoro uye zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Vanamukoti vako vanogona kupa zviyero zvekunyaradza kubatsira kubata chero kusagadzikana kwaunowana.

Nepo zvisingawanzoitiki, vamwe vanhu vanogona kusangana nemhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza:

• Maitiro akakomba ekuita allergic ane rash, kuzvimba, kana kuoma kufema
• Kuchinja kukuru mumoyo rhythm
• Manyoka akakomba anogona kuratidza hutachiona hwechipiri
• Kusagadzikana kwemhasuru kana kurwadziwa
• Zviratidzo zvematambudziko echiropa senge kuita yero yeganda kana maziso

Vashandi vehutano vako vanokutarisa nguva dzose, saka vachakurumidza kuziva uye kugadzirisa chero zviratidzo zvinonetsa. Usazeze kuudza mukoti wako nezve chero zviratidzo zvitsva kana kuwedzera, zvisinei kuti zvingaite sei.

Ndiani Asingafaniri Kutora Lefamulin?

Lefamulin haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuisa. Vanhu vane mamiriro emoyo kana avo vari kutora mishonga yakati wandei vangangoda dzimwe nzira dzekurapa.

Chiremba wako achadzivisa kukupa lefamulin kana uine mamiriro kana mamiriro akati wandei:

• Kuzivikanwa allergy ku lefamulin kana maantibayoti akafanana
• Zvimwe zvirwere zvemoyo rhythm (QT kuwedzera)
• Chirwere chechiropa chakakomba
• Kuzvitakura kana kuyamwisa (chengetedzo haina kumiswa)
• Zera pasi pemakore gumi nemasere (haina kudzidzwa muvana)

Zvakare, lefamulin inogona kuita zvinhu pamwe chete nemimwe mishonga, kunyanya iyo inokanganisa rhythm yemoyo kana kugadziriswa nechiropa. Chikwata chako chekuchengetwa kwehutano chichaongorora mishonga yako yese iripo kuti ive nechokwadi chekuti lefamulin yakachengeteka kwauri.

Kana uine matambudziko echiropa ari nyoro kusvika pakati nepakati, chiremba wako angangodaro achakupa lefamulin asi achakutarisa zvakanyanya uye pamwe achigadzirisa muyero. Nguva dzose zivisa chikwata chako chekuchengetwa kwehutano nezve mishonga yese, zvinowedzera, uye zvigadzirwa zvemiti yaunotora.

Mazita eBrand eLefamulin

Lefamulin inowanikwa pasi pezita rebrand Xenleta muUnited States. Iri ndiro zita rekutanga rebrand rauchaona pamarekodhi emishonga yechipatara uye magwaro einishuwarenzi.

Mishonga iyi inogadzirwa neNabriva Therapeutics uye itsva kumusika, mushure mekubvumidzwa neFDA muna 2019. Nekuti mushonga mutsva weantibiotic, shanduro dzakajairika hadzisati dziripo.

Pharmacy yako yechipatara inogona kureva kwairi nezita rayo rakajairika (lefamulin) uye zita rebrand (Xenleta) mumarekodhi ako ekurapa. Mazita ese ari maviri anoreva mushonga mumwe chete.

Zvimwe Zvingasarudzwa zveLefamulin

Kana lefamulin isina kukodzera iwe, chiremba wako ane mamwe maantibiotics anoshanda ekurapa pneumonia yebhakitiriya. Sarudzo inoenderana nehutachiona hwako chaihwo, nhoroondo yako yekurapa, uye kuti unotsungirira sei mishonga yakasiyana.

Zvimwe zvinowanzo shandiswa kurapa pneumonia yebhakitiriya zvinosanganisira:

• Ceftriaxone (antibiotic ye cephalosporin)
• Azithromycin (antibiotic ye macrolide)
• Levofloxacin (antibiotic ye fluoroquinolone)
• Vancomycin (yekurapa hutachiona hwebhakitiriya hunodzivisa)
• Linezolid (imwe sarudzo yebhakitiriya inodzivisa)

Chiremba wako achasarudza imwe nzira yakanakisa zvichienderana nemhedzisiro yetsika inoratidza mabhakitiriya chaiwo anokonzera hutachiona hwako. Vachafungawo nezve basa rako reitsvo nechiropa, chero allergy yemishonga, uye mimwe mishonga yaunotora.

Dziri nguva dzose vanachiremba vanoshandisa kurapa nekubatanidza mishonga, vachikupa mishonga miviri yakasiyana pamwechete kuti vave nechokwadi chekuti vari kufukidza mabhakitiriya ese anogona kuitika. Nzira iyi inowanzo shandiswa kana urwere zvakanyanya kana kana chikonzero chaicho chemapfumo ako chisinganyatsojeki pakarepo.

Ko Lefamulin Ari Nani Kupfuura Mamwe Mishonga?

Lefamulin haisi zvakanyanya "nani" kupfuura mamwe mishonga, asi inopa zvakanakira zvakasiyana mumamiriro akati wandei. Bhenefiti yayo huru ndeyekuti inoshanda zvakasiyana nemamwe mishonga, zvichiita kuti ive inoshanda pamabhakitiriya mamwe akava nemishonga yekurapa.

Zvidzidzo zvekiriniki zvinoratidza kuti lefamulin inoshanda semamwe mishonga yakajairika yekurapa pneumonia yebhakitiriya. Zvisinei, kukosha kwayo kwechokwadi kuri mukupa vanachiremba chimwe chishandiso kana mishonga yekutanga isingashande kana isina kukodzera murwere.

Maitiro akasiyana emushonga anoita kuti ave akakosha muhondo yedu iripo yekurwisa mabhakitiriya anoramba mishonga. Haina kuitirwa kutsiva mamwe mishonga asi kuti iwedzere kune iwo sechikamu chenzira yakazara yekurapa zvirwere zvakakomba.

Mibvunzo Inowanzo Bvunzwa Nezve Lefamulin

Ko Lefamulin Akachengeteka Kune Vanhu vane Chirwere Chemoyo?

Lefamulin inoda kufunga zvakanyatsonaka kana uine chirwere chemoyo, kunyanya matambudziko mamwe erhythm. Mushonga unogona kukanganisa mabasa emagetsi emoyo wako, ndosaka chiremba wako achatarisa hutano hwemoyo wako asati wanyora.

Kana uine nhoroondo yematambudziko erhythm emoyo, timu yako yehutano ichakutarisa nekutarisa kwemoyo nguva dzose panguva yekurapa. Vachatarisawo mazinga ako e-electrolyte, sezvo kusagadzikana kunogona kuwedzera njodzi yekuchinja kwemoyo.

Vanhu vazhinji vane chirwere chemoyo vanogona kugamuchira lefamulin zvakachengeteka nekutarisa kwakakodzera. Chiremba wako achayerera mabhenefiti ekurapa hutachiona hwako hwemapapu hwakakomba pamwe chete nenjodzi dzese dzemoyo.

Ndingaita Sei Kana Ndikawana Zvinhu Zvakaipa Zvikuru?

Kana ukaona zvinhu zvakaipa zvikuru uchipiwa lefamulin, udza mukoti wako kana chiremba wako nekukasira. Nekuti uri muchipatara, rubatsiro rwekurapa runowanikwa nguva dzose kuti ruzive zviratidzo zvinonetesa nekukurumidza.

Kusangana nezvinhu zvinokonzerwa neallergy zvakanyanya hazviwanzoitiki asi zvinoda kurapwa nekukasira. Zviratidzo zvinosanganisira kuoma kufema, kuzvimba kwechiso chako kana huro, kana rash yakapararira. Chikwata chako chehutano chakadzidziswa kuziva nekukurumidza nekurapa izvi.

Kune zvimwe zvinokonzeresa zvakanyanya senge kurwadziwa muchipfuva, dzungu rakanyanya, kana zviratidzo zvisingawanzoitiki, mukoti wako achakutarisisa ipapo ipapo uye achabata chiremba wako kana zvichidikanwa. Usanetseka nezve "kunetsa" vashandi - vanoda kuziva nezvezviratidzo zvauri kusangana nazvo.

Ndingachinja kuOral Antibiotics Ndichitora Lefamulin?

Parizvino, lefamulin inowanikwa chete semushonga weIV, saka haugone kuchinja kuutora nemuromo. Zvisinei, chiremba wako angakuchinjira kune imwe antibiotic yemuromo kana mamiriro ako achivandudza zvakakwana kuti ubve muchipatara.

Sarudzo yekuchinjira kuoral antibiotics inoenderana nekuti uri kupindura sei kurapwa uye kana wakagadzikana zvakakwana kuti uende kumba. Chiremba wako achafunga nezvefivha yako, kufema, uye kuvandudzwa kwese kwekiriniki.

Kana ukachinjira kuoral antibiotic, zvingangove mushonga wakasiyana zvachose. Chiremba wako achasarudza imwe yakakodzera kuenderera mberi nekurapa kwako kumba.

Ndoziva Sei Kana Lefamulin Ichishanda?

Unogona kutanga kuona kuvandudzwa muzviratidzo zvako mukati memazuva mashoma ekutanga ekurapa. Kufema kwako kunogona kuve nyore, fivha yako inofanira kutanga kudzikira, uye pamwe uchavamba kunzwa usina kuneta uye uchinzwa semunhu wako.

Vashandi venyu vezvehutano vachatevera kufambira mberi kwenyu kuburikidza nekuongorora nguva dzose zviratidzo zvenyu zvehutano, bvunzo dzeropa, uye maX-rays emapapu. Vachakubvunzaiwo nezvezviratidzo zvenyu uye kuti munonzwa sei pakawanda.

Vanhu vazhinji vanoona kuvandudzika kukuru mukati memazuva matatu kusvika mashanu ekutanga lefamulin. Kana musiri kuvandudzika sezvaitarisirwa, chiremba wenyu angachinja chirongwa chenyu chekurapa kana kuongorora zvimwe zvinogona kukonzera zviratidzo zvenyu.

Ndichada Kuchengetwa Kwekuenderera Mberi Mushure mekurapwa kweLefamulin here?

Hongu, munogona kuda kuchengetwa kwekuenderera mberi mushure mekupedza kurapwa kwenyu kwelefamulin. Izvi zvinobatsira kuona kuti hutachiona hwenyu hwanyatsoenda uye kuti muri kupora zvakanaka kubva ku pneumonia yenyu.

Chiremba wenyu anowanzo gadzirisa nguva yekusangana mukati mevhiki 1 kusvika 2 mushure mekubuda muchipatara. Vanogona kuraira X-ray yemapapu kuti vasimbise kuti mapapu enyu ari kupora zvakanaka uye vatarise basa reropa renyu kuti vaone kuti basa rechiropa chenyu radzoka kune zvakajairika.

Vamwe vanhu vangada kuenderera mberi, kunyanya kana vakave nematambudziko kana kutora nguva yakareba kupindura kurapwa. Vashandi venyu vezvehutano vachapa mirairo yakajeka yekuti moteerera chii kumba uye kuti mungatsvaga rini kutarisirwa kwekurapa kana zvichidikanwa.