Chii chinonzi Methoxsalen: Zvinoshandiswa, Madosi, Migumisiro Yakaipa uye Zvimwe

Methoxsalen mushonga unopiwa nachiremba unoita kuti ganda rako rive sensitive kune ultraviolet light, richibatsira kurapa mamwe mamiriro eganda senge psoriasis uye vitiligo. Iyi nzira yakasarudzika inoshanda nekubatanidza mushonga nechiedza therapy chinodzorwa kubatsira ganda rako kupora uye kudzorera ruvara rwaro rwechisikigo kana kujekesa zvikamu zvakaoma.

Unogona kunge uchinetseka kuti piritsi rinogona sei kushanda nechiedza kurapa matambudziko eganda. Funga nezve methoxsalen semubatsiri anogadzirira maseru eganda rako kuti apindure zvirinani kumafungu chaiwo eUV light, achigadzira kurapwa kwakanangana uko kwave kuchibatsira vanhu kwemakumi emakore.

Chii chinonzi Methoxsalen?

Methoxsalen ndeyeboka remishonga inonzi psoralens, iyo iri makomisheni anowanikwa zvakasikwa anowedzera kunzwisisika kweganda rako ku ultraviolet A (UVA) light. Paunotora mushonga uyu nemuromo, unofamba nemuropa rako uye unonyanya kuita mumaseru eganda rako, uchiita kuti apindure zvakanyanya kune chiedza therapy.

Mushonga uyu unogara uchishandiswa sechikamu chekurapa chinonzi PUVA therapy, iyo inomirira Psoralen plus UVA light. Chiremba wako achanyatso kuronga nguva yemushonga wako nekuchengetedzwa kwechiedza kurapwa kuti uwane mhedzisiro yakanaka uchikuchengetedza.

Chii chinonzi Methoxsalen chinoshandiswa?

Methoxsalen inorapa mamiriro akati wandei eganda akaoma ayo asina kupindura zvakanaka kune mamwe marapirwo. Kushandiswa kwakajairika ndeye psoriasis yakakomba, uko inobatsira kuderedza kukura nekukurumidza kwemasero eganda anogadzira makuru, ane scaly patches.

Kupfuura psoriasis, mushonga uyu unogona kubatsira ne vitiligo, mamiriro apo zvikamu zve ganda zvinorasikirwa neruvara rwavo rwechisikigo. Heano mamiriro makuru ayo methoxsalen inogona kutaura:

• Psoriasis yakanyanya iyo inovhara nzvimbo huru dzemuviri wako
• Vitiligo, kunyanya kana ichikanganisa nzvimbo dzinooneka semaoko nechiso
• Cutaneous T-cell lymphoma, rudzi rwegomarara reganda
• Mycosis fungoides, imwe mhando ye lymphoma inokanganisa ganda

Chiremba wako anowanzo kuraira methoxsalen kana dzimwe nzira dzekurapa dzisina kushanda zvakanaka kana mamiriro ako akakomba zvakakwana kuti vashandise nzira iyi yakanyanya.

Methoxsalen Inoshanda Sei?

Methoxsalen inoshanda nekuita kuti maseru ako eganda ave sensitive kune UVA chiedza, icho chinobva chaita shanduko dzinobatsira mukukura uye kushanda kwemasero ako. Kana yakasanganiswa nekujekeswa kwechiedza chinodzorwa, inogona kuderedza kugadzirwa kwemasero eganda akawandisa kana kubatsira kudzorera pigmentation yakajairika.

Izvi zvinoonekwa sekurapa kwakasimba zvine mwero kunoda kutarisirwa kwechiremba. Mushonga uyu unonyanya kuita se photosensitizer, zvinoreva kuti inoita kuti ganda rako riite zvakanyanya kune chiedza kupfuura zvazvingaita. Iyi mhinduro inodzorwa ndiyo inobatsira kurapa mamiriro ako eganda, asi zvinorevawo kuti unofanirwa kungwarira zvakanyanya nezvekuisa zuva.

Ndinofanira Kutora Sei Methoxsalen?

Tora methoxsalen sezvinorairwa nachiremba wako, kazhinji 1.5 kusvika kumaawa maviri usati wapiwa UVA light treatment. Nguva yacho yakakosha nekuti mushonga unoda nguva yekutenderera mumuviri wako uye kusvika kumasero ako eganda vasati vatanga kurapwa kwechiedza.

Nguva dzose tora mushonga uyu uine chikafu kana mukaka kubatsira kuderedza dumbu uye kuvandudza kunyudzwa. Chikafu chakareruka kana snack chinoshanda zvakanaka, asi dzivisa chikafu chinorema, chine mafuta chinogona kukanganisa maitiro emuviri wako ekugadzirisa mushonga.

Hezvino zvaunofanira kuziva nezvekutora methoxsalen nemazvo:

• Momedza makapisi ese nemvura yakawanda
• Usapwanya, kutsenga, kana kuvhura makapisi
• Tora panguva imwechete usati watora kurapwa kwechiedza
• Idya chimwe chinhu chakareruka maminitsi makumi matatu usati watora mushonga
• Dzivisa muto wemazambiringa, unogona kukanganisa maitiro emuviri wako emushonga

Chiremba wako achakupa mirairo yakajeka nezve nguva, uye zvakakosha kuitevera chaizvo kuchengetedzeka uye kushanda zvakanaka.

Ndingatora Methoxsalen kwenguva yakareba sei?

Kureba kwekurapwa kwe methoxsalen kunosiyana zvakanyanya zvichienderana nemamiriro ako chaiwo uye kuti unopindura sei kurapwa. Vanhu vazhinji vanoda kurapwa 2-3 nguva pavhiki kwemavhiki akati wandei kana mwedzi kuti vaone kuvandudzwa kukuru.

Psoriasis, unogona kuda kurapwa 15-25 usati ganda rako rachena zvakanyanya. Kurapwa kweVitiligo kazhinji kunotora nguva yakareba, dzimwe nguva 6-12 mwedzi kana kupfuura, nekuti repigmentation inoitika zvishoma nezvishoma. Chiremba wako achatarisa kufambira mberi kwako zvakanyanya uye achagadzirisa chirongwa chekurapa sezvinodiwa.

Kana mamiriro ako akavandudzika, unogona kuda kurapwa kwenguva pfupi kuti uchengetedze ganda rako riine hutano. Vamwe vanhu vanogona kumisa kurapwa zvachose, nepo vamwe vachibatsirwa nemasesheni enguva nenguva kudzivirira kupararira.

Ndezvipi Zvakaipa zveMethoxsalen?

Semishonga yese, methoxsalen inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Mhedzisiro yakajairika inowanzoita nyoro uye inogoneka nekutarisirwa kwakakodzera uye kuongorora.

Heano mhedzisiro yakajairika yaungasangana nayo:

• Nausea kana dumbu, kunyanya kana yakatorwa isina chikafu
• Kuwedzera kunzwisiswa kwezuva kwemaawa makumi maviri nemana-48 mushure mekurapwa
• Kupisa kudiki kana kunzwa kwekuvava panguva yekurapa kwechiedza
• Kusviba kwenguva pfupi kwenzvimbo dzeganda dzakarapwa
• Dizziness kana kurwadziwa mumusoro mune vamwe vanhu

Mhedzisiro iyi inowanzoita nani sezvo muviri wako uchigadzirisa kurapwa, uye chikwata chako chekuchengetedza hutano chinogona kukubatsira kuzvitarisira zvinobudirira.

Mhedzisiro yakakomba inowanzoitika asi inoda kutariswa kwekurapa nekukurumidza. Bata chiremba wako nekukurumidza kana ukaona:

• Kupisa kwakanyanya kana kuita mablister paganda rako
• Zviratidzo zvekunyanya kupisa nezuva kunyangwe nekushaikwa kwezuva
• Kusvotwa kana kurutsa kunoramba kuripo
• Kuchinja kweganda kusinganzwisisike kana kukura
• Matambudziko emeso senge kunyanya kunzwisisa chiedza kana shanduko dzekuona

Chiremba wako achakutarisa zvakanyatso panguva yekurapa kuti abate chero matambudziko kare uye agadzirise kurapwa kwako kana zvichidikanwa.

Ndiani Asingafaniri Kutora Methoxsalen?

Methoxsalen haina kuchengeteka kune vese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira. Mamwe mamiriro anoita kuti kurapwa uku kuve kwakanyanya njodzi, nepo mamwe achida kungwarira kwakawanda uye kutariswa.

Haufaniri kutora methoxsalen kana uine:

• Nhoroondo yekenza yeganda, kunyanya melanoma
• Chirwere chakakomba chechiropa kana matambudziko eitsvo
• Cataracts kana mamwe mamiriro akakomba emeso
• Lupus kana mamwe mamiriro eautoimmune anowedzera nekuiswa kwezuva
• Albinism kana mamwe mamiriro anoita kuti unzwe zvakanyanya chiedza

Chiremba wako achashandisawo kungwarira kwakawanda kana iwe wakazvitakura, uchiyamwisa, kana uine nhoroondo yemhuri yekenza yeganda. Zera rinogona kuve chinhu zvakare, sezvo vanhu vakuru vangave vachinyanya kunzwisisa kumishonga yese nekurapa kwechiedza.

Mazita eMethoxsalen Brand

Methoxsalen inowanikwa pasi pemazita akati wandei emhando, neOxsoralen-Ultra ndiyo inonyanya kurairwa fomu remuromo muUnited States. Mhando iyi ine methoxsalen mune yakapfava gelatin capsule yakagadzirirwa kunyudzwa kuri nani.

Mamwe mazita emhando anosanganisira Oxsoralen (makapisi akaoma) uye 8-MOP, kunyangwe izvi zvingave zvisingawanikwe zvakanyanya. Mushonga wako unogona zvakare kuve nemhando dzemethoxsalen, iyo inoshanda zvakanyanya semhando dzemhando.

Zvimwe Zvinotsiva Methoxsalen

Kana methoxsalen isiri iyo yakakunakira iwe, akati wandei ekurapa anogona kubatsira kubata psoriasis, vitiligo, uye mamwe mamiriro eganda. Chiremba wako anogona kukurudzira kurapwa kwepamusoro, mamwe marapirwo echiedza, kana mishonga mitsva zvichienderana nemamiriro ako chaiwo.

Ye psoriasis, zvimwe zvinosanganisira topical corticosteroids, vhitamini D analogs, kana mishonga mitsva yebiologic inonangana nezvikamu zvakasiyana zve immune system yako. Narrowband UVB light therapy imwe sarudzo isingade mushonga zvachose.

Vitiligo zvimwe zvinosanganisira topical immunomodulators, corticosteroid creams, kana kurapwa kutsva senge JAK inhibitors. Vamwe vanhu vanobatsirwawo nekutora tattoo kana makeup kuti vafukidze nzvimbo dzakakanganiswa vachitsvaga mamwe marapirwo.

Ko Methoxsalen Zviri Nani Kupfuura Zvimwe Zvirwere zvePsoriasis?

Methoxsalen ine PUVA therapy inoshanda zvakanyanya kune yakakomba psoriasis, kazhinji ichibvisa 75-90% yezvironda zvepaganda kana mamwe marapirwo asina kushanda. Zvisinei, "zviri nani" zvinoenderana nemamiriro ako chaiwo, hutano hwese, uye zvinangwa zvekurapa.

PUVA therapy inoshanda zvakanyanya pakurapa psoriasis yakapararira iyo inovhara nzvimbo hombe dzemuviri wako. Yave ichishandiswa zvinobudirira kwemakumi emakore uye inogona kupa kuregererwa kwenguva refu kune vanhu vazhinji. Zvisinei, kurapwa kunoda kushanya kwakawanda kukiriniki uye kunotakura njodzi dzenguva refu.

Mishonga mitsva yebiologic inogona kunge iri nyore sezvo ichipiwa semajekiseni mumasvondo mashoma kana mwedzi. Ivo zvakare vanoshanda zvakanyanya uye vanogona kuve nemhedzisiro shoma yenguva refu. Chiremba wako achakubatsira kuyera mabhenefiti nenjodzi dzesarudzo imwe neimwe zvichibva pazvido zvako.

Mibvunzo Inowanzo Bvunzwa Nezve Methoxsalen

Mubvunzo 1. Ko Methoxsalen Yakachengeteka Kune Vanhu vane Chirwere Chemoyo?

Methoxsalen inogona kushandiswa zvakachengeteka muvanhu vane chirwere chemoyo, asi chiremba wako achafanira kukutarisa zvakanyanya. Mushonga wacho pachake hauna zvakananga mwoyo wako, asi kushushikana kwekurapa uye mukana wekushaya mvura kubva kurapwa kwechiedza kunoda kutarisirwa zvakanyanya.

Chiremba wako wemoyo uye chiremba wemagariro anofanira kuronga kutarisirwa kwako kuti ave nechokwadi chekuti mishonga yako yese inoshanda zvakanaka pamwe chete. Ita shuwa yekuti unoudza vese vanachiremba nezve mishonga yako yese yemoyo, sezvo vamwe vachigona kuwedzera kunzwisiswa kwezuva.

Mubvunzo 2. Ndingaita Sei Kana Ndikatora Methoxsalen Yakawanda Netsaona?

Kana netsaona ukatora methoxsalen yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira, kunyangwe ukanzwa zvakanaka. Kutora zvakanyanya kunogona kukuita kuti unzwe zvakanyanya kuchiedza uye kuwedzera njodzi yako yekupisa zvakanyanya.

Dzivisa zuva rese uye mwenje wepamba wakajeka kusvikira wawana zano rekurapa. Usaedze kuzviita kuti urutse kunze kwekunge wataurirwa zvakananga kuti uite saizvozvo nenyanzvi yehutano.

Mubvunzo 3. Ndingaita Sei Kana Ndikarasikirwa neDose yeMethoxsalen?

Kana ukakanganwa dose ye methoxsalen, usaitore kunonoka kana kuedza kuigadzirisa. Sezvo mushonga uyu wakarongeka nenguva yekugadzwa kwako kwekurapa kwechiedza, kukanganwa dose zvinoreva kuti uchafanirwa kuronga zvakare chikamu chako chekurapa.

Taura nehofisi yachiremba wako nekukasira sezvinobvira kuti uronge zvakare mushonga uye kurapwa kwechiedza. Usambofa wakatora dose kaviri kuti ubate, sezvo izvi zvingave zvine njodzi.

Mubvunzo 4. Ndingamira Rini Kutora Methoxsalen?

Unogona kumira kutora methoxsalen kana chiremba wako aona kuti zvinangwa zvako zvekurapa zvazadzikiswa uye mamiriro ako eganda akadzorwa zvakanaka. Sarudzo iyi inofanirwa kugara ichiitwa pamwe chete nechikwata chako chehutano pane wega.

Kune vanhu vazhinji, kurapwa kunoenderera mberi kusvika maronda paganda apera zvakanyanya kana kuti ruvara rweganda rwadzoka kusvika padanho rinogutsa. Chiremba wako achabva akukurukura kana uchida kurapwa kwekuchengetedza kana kuti unogona kumira zvachose.

Q5. Ndingashandisa Sunscreen Ndiri Kutora Methoxsalen Here?

Unofanira kushandisa sunscreen nguva dzose paunenge uchitora methoxsalen, asi nguva yacho yakakosha. Pamazuva ekurapwa, usaise sunscreen kunzvimbo dziri kurapwa kusvika pashure pechikamu chako chekurapa nechiedza, sezvo ichi chingakanganisa kurapwa.

Kune dzimwe nzvimbo dzemuviri wako uye pamazuva asiri ekurapwa, shandisa sunscreen yakakura-spectrum ine SPF 30. Ganda rako richave richinyanya kunzwisisa kukuvadzwa nezuva kwemaawa 24-48 mushure mekurapwa kwega kwega, saka kuchengetedzwa kwezuva kwakakosha kudzivirira kupisa uye kukuvadzwa kweganda kwenguva refu.