Chii chinonzi Neostigmine Methylsulfate uye Glycopyrrolate: Kushandiswa, Dosage, Side Effects uye Zvimwe

Neostigmine methylsulfate uye glycopyrrolate mushonga unosanganiswa unopiwa kuburikidza neIV kuti ubvise mhedzisiro yemishonga inozorodza tsandanyama inoshandiswa panguva yekuvhiya. Mushonga uyu unojekesa unobatsira tsandanyama dzako kuti dzidzoke basa radzo rakajairika mushure me general anesthesia, zvichikubvumira kuti ufunge uye ufambe zvakanaka wega zvakare.

Mubatanidzwa unoshanda seboka - neostigmine inoita basa guru nekudzosa paralysis yetsandanyama, nepo glycopyrrolate inodzivirira moyo wako uye inodzivirira mhedzisiro isingafadzi. Funga nezvazvo semubatanidzwa wakanyatsoenzaniswa unobatsira kuchinjisa muviri wako zvakachengeteka kubva mukamuri yekuvhiya kuenda kubasa rakajairika.

Chii chinonzi Neostigmine Methylsulfate uye Glycopyrrolate?

Mushonga uyu unosanganisa zvinoshanda zviviri zvinoshanda pamwechete kuti zvibvise zvakachengeteka mhedzisiro yeanesthesia. Neostigmine methylsulfate is cholinesterase inhibitor inodzivisa ma enzymes anodzivirira kufamba kwetsandanyama, nepo glycopyrrolate iri anticholinergic inorwisa mhedzisiro isingadiwe yemoyo uye yekugaya.

Iwe unongogamuchira mushonga uyu muchipatara kana nzvimbo yekuvhiya. Vapi vehutano vanoi shandisa zvakananga panguva yekupora kwekuvhiya kana yasvika nguva yekumutsa tsandanyama dzako uye kudzorera kufema kwakajairika. Mubatanidzwa unovimbisa kuchinjisa kwakatsetseka, kwakachengeteka kubva ku anesthesia.

Chii chinonzi Neostigmine Methylsulfate uye Glycopyrrolate inoshandiswa?

Mushonga uyu unodzosa neuromuscular blockade, iyo izwi rekurapa rekunyarara kwetsandanyama kwenguva pfupi kunoshandiswa panguva yekuvhiya. Paunenge uri pasi pe general anesthesia, vanachiremba vanowanzo kupa mishonga inozorodza tsandanyama kuti vakuchengete wakanyarara zvachose uye kuti kufema kuve nyore neventilator.

Chinhu chikuru chinoshandiswa ndechokubatsira varwere kuti vadzore kutonga kwemhasuru pakupera kwekuvhiyiwa. Pasina mushonga uyu wokudzosa, mishonga inozorodza mhasuru inogona kutora maawa kuti ipere zvakasikwa, ichikuchengeta pamuchina wokufema kwenguva refu kupfuura zvakafanira.

Muzviitiko zvisingawanzoitiki zvekukurumidzira, vanachiremba vanogonawo kushandisa musanganiswa uyu kurapa kusimba kwakanyanya kwemhasuru kubva kune zvimwe zvirwere zvekurapa. Zvisinei, izvi zvinomiririra chikamu chiduku kwazvo chekushandiswa kwayo kwose kwekurapa, uye zvisarudzo zvakadaro zvinoda kuongororwa kwakanyanya kwengozi nemabhenefiti.

Neostigmine Methylsulfate ne Glycopyrrolate Zvinoshanda Sei?

Iri rinotariswa semushonga une simba zvishoma rinobata kuburikidza nemaitiro chaiwo ebiological. Neostigmine inodzivisa acetylcholinesterase, enzyme inowanzo putsa acetylcholine - mutumwa wemakemikari uyo unoudza mhasuru dzako kuti dzibvumirane.

Kana acetylcholinesterase yakavharwa, acetylcholine yakawanda inowanikwa kuti ishandise fiber dzemhasuru. Izvi zvinokunda mishonga inozorodza mhasuru ichiri mumuviri wako uye inobvumira basa remhasuru rakajairika kuti ridzoke. Maitiro acho anowanzo kutanga kushanda mukati me1-2 maminitsi ekujekesa.

Glycopyrrolate inotamba basa rekudzivirira nekudzivisa muscarinic receptors mumuviri wako wose. Pasina dziviriro iyi, kuwedzera kweacetylcholine kungakonzera mhedzisiro ine matambudziko senge kuderera kwemoyo, kugadzirwa kwemate akawandisa, uye cramping yekugaya. Musanganiswa uyu unoona kuti kupora kwemhasuru kunoitika zvakachengeteka.

Ndingatora Sei Neostigmine Methylsulfate ne Glycopyrrolate?

Hauzozvitore iwe pachako mushonga uyu - unotungamirirwa chete nenyanzvi dzehutano dzakadzidziswa muzvivakwa zvekurapa. Jekiseni rinoenda zvakananga mumutsara wako weIV iwe uchiri pasi pekutariswa kwekurapa mukamuri yekuvhiya kana nzvimbo yekupora.

Chiremba wako weanesthesia kana mukoti weanesthesia vachaverenga chiyero chaicho zvichienderana nehuremu hwako, rudzi rwemushonga wekuzorodza mhasuru unoshandiswa, uye kuti muviri wako uri kupindura sei. Vachatarisa kufema kwako, kumhanya kwemoyo, uye simba remhasuru nguva dzose panguva uye mushure mejekiseni.

Hapana kugadzirira kwakakosha kunodiwa kubva kwauri sezvo ungave uchiri kurara kubva kuesthesia. Chikwata chako chekurapa chinobata zvese zvinhu zvekuisa nguva uye kutarisira kuti uve nechokwadi chekuti kupora kwakachengeteka kubva mukuvhiya kwako.

Ndingatora Neostigmine Methylsulfate uye Glycopyrrolate kwenguva yakareba sei?

Mishonga iyi inopiwa sejekiseni rimwe chete kana akatevedzana emajekiseni panguva imwe chete yekurapa. Kusiyana nemishonga yezuva nezuva yaungatora kumba, musanganiswa uyu unoshandiswa chete panguva chaiyo yaunenge uchipora kubva kuesthesia.

Mhedzisiro yacho inowanzo gara maminitsi makumi matatu kusvika makumi matanhatu, izvo zvinowanzoita nguva yakakwana yekuti zvinzorodza mhasuru zvibude mumuviri wako zvakasikwa. Chikwata chako chekurapa chichakutarisa panguva ino yese kuti uve nechokwadi chekuti mhasuru dzako nekufema zvinodzokera kusimba rakajairika.

Hauchazodi kuenderera mberi nemishonga iyi mushure mekubuda muchipatara. Kana kuvhiyiwa kwako kwapera uye wapora kubva kuesthesia, hapana kurapwa kuri kuenderera mberi kunodiwa nemusanganiswa uyu.

Ndezvipi Zvakaipa zveNeostigmine Methylsulfate uye Glycopyrrolate?

Vanhu vazhinji vanowana zvishoma zvinokonzeresa nekuti mishonga inonyatsoenzaniswa uye inopiwa pasi pekutariswa kwekurapa kwepedyo. Zvisinei, muviri wako ungaita sezvaunojairana kubva kune anesthetized state kudzokera kune yakajairika basa.

Zvinowanzoitika zvaungacherechedza zvinosanganisira kusvotwa kudiki, muromo wakaoma, kana kunzwa uchishaya simba zvishoma sezvaunomuka. Mhedzisiro iyi inowanzoita yenguva pfupi uye kazhinji yakaoma kusiyanisa kubva kune zvakajairika zviratidzo zvekupora mushure mekuvhiyiwa. Chikwata chako chekurapa chinotarisira izvi uye chinogona kupa zviyero zvekunyaradza kana zvichidiwa.

Zvisingawanzoitiki asi zvinoonekwa zvakanyanya zvinogona kusanganisira:

• Kukurumidza kwemoyo kana kurova kwemoyo kusingaite zvakanaka
• Kutsimwaira kwemhasuru kana kusava nesimba
• Kutadza kuisa pfungwa pakuona kwako
• Kusagadzikana kana kuvhiringidzika
• Kutukirwa zvakanyanya

Izvi zvinowanzoitika nekukurumidza sezvo muviri wako uchigadzirisa, asi timu yako yezvokurapa ichakutarisa zvakanyanya uye ichapa kurapwa kana chero chikasava chakanaka kana kukonzera kunetseka.

Zvisingawanzoitiki asi zvakakomba zvinokonzeresa zvinoda kutariswa kwekurapa nekukurumidza uye zvinosanganisira maitiro akakomba ekuita allergic, matambudziko makuru ekufema, kana shanduko huru dzemoyo. Vapi vako vehutano vakadzidziswa kuziva nekubata matambudziko aya nekukurumidza, zvichiita kuti maitiro akakomba ave nyore kwazvo muchipatara.

Ndiani Asingafaniri Kutora Neostigmine Methylsulfate uye Glycopyrrolate?

Mamwe mamiriro ezvinhu ezvokurapa anoita kuti mushonga uyu usakodzere kana kuda matanho akakosha. Vanhu vane matambudziko akakomba emoyo, glaucoma isina kurapwa, kana chirwere chakakomba cheitsvo vangangoda dzimwe nzira dzekudzosa anesthesia.

Anesthesiologist wako achatarisa nhoroondo yako yezvokurapa yakazara pamberi pekuvhiyiwa kuti azive chero mamiriro angakanganisa sarudzo dzemishonga. Mamiriro anoda kungwarira zvakanyanya anosanganisira myasthenia gravis, asthma yakakomba, kana maitiro ekare ekuita allergic kumishonga yakafanana.

Kuzvitakura nekuyamwisa zvinoda kufunga zvakanyanya, kunyangwe mushonga unogona kushandiswa kana mabhenefiti achipfuura njodzi dzinogona kuitika. Chikwata chako chekurapa chichakurukura izvi newe panguva yekubvunzana kwako kwekuvhiya kana zvichishanda kumamiriro ako ezvinhu.

Muzviitiko zvisingawanzoitiki, vanhu vane humwe hutachiona hwejenetiki vangangogadzirisa mushonga uyu zvakasiyana. Zvisinei, mamiriro aya anowanzozivikanwa kuburikidza nenhoroondo yemhuri kana zviitiko zvekare zvekurapa, uye chikwata chako chehutano chinogona kuronga zvinoenderana.

Neostigmine Methylsulfate uye Glycopyrrolate Mazita eBrand

Mubatanidzwa uyu unowanikwa pasi pezita rekuti Bridion mune dzimwe nzira, kunyangwe mubatanidzwa chaiwo we neostigmine uye glycopyrrolate unogona kugadzirwa nemakemisi emuchipatara. Nzvimbo zhinji dzemishonga dzinoshandisa mubatanidzwa we generic wakagadzirwa zvinoenderana nemaitiro akajairwa.

Unogona zvakare kunzwa vanopa hutano vachitaura nezvazvo zviri nyore se "vashandi vekudzosa" kana "vashandi vanopesana" panguva yekuvhiyiwa kwako. Zita chairo remhando rinokosha zvishoma pane chokwadi chekuti uri kugamuchira mubatanidzwa wakaratidzwa, wakachengeteka wekudzosa anesthesia.

Zvimwe Zvinhu Zviri Kutsiva Neostigmine Methylsulfate uye Glycopyrrolate

Zvimwe zvinhu zviripo zvekudzosa zvinodzorera mhasuru, nesugammadex iri sarudzo itsva inoshanda zvakasiyana ne neostigmine. Sugammadex inosungirira zvakananga kune dzimwe nzvimbo dzinodzorera mhasuru panzvimbo yekuvharisa ma enzymes, zvichikwanisa kupa kudzoserwa nekukurumidza mune dzimwe nguva.

Anesthesiologist wako angasarudza edrophonium ine atropine seimwe sarudzo yemubatanidzwa, kunyangwe izvi zvisingawanzo shandiswa nhasi. Sarudzo inoenderana nekuti ndeipi mhasuru relaxant yakashandiswa panguva yekuvhiyiwa kwako uye zvinhu zvako zvekurapa.

Mune dzimwe nguva, kungobvumira nguva yekuti metabolism yechisikigo iitike ingave yakakodzera, kunyanya nemhasuru dzinodzorera dzinoshanda kwenguva pfupi. Zvisinei, nzira iyi inoda kugara kwenguva refu mukamuri rekupora uye kuenderera mberi kwemhepo yekufema, zvichiita kuti kudzoserwa kunoshanda kuve kunofarirwa.

Ko Neostigmine Methylsulfate uye Glycopyrrolate Zviri Nani Kupfuura Sugammadex?

Mishonga yose miviri inodzorera zvinobudirira mhasuru relaxants, asi inoshanda kuburikidza nemaitiro akasiyana uye ine zvakanakira zvakasiyana. Neostigmine ine glycopyrrolate ine makumi emakore ekuchengeteka kwakaratidzwa uye inoshanda nemhando dzese dzemhasuru relaxants, nepo sugammadex ichipa kudzoserwa nekukurumidza kune chaiwo mhasuru relaxants itsva.

Sarudzo "yakanaka" inoenderana nemamiriro ako chaiwo ekuvhiya, nhoroondo yako yekurapa, uye rudzi rwemushonga wekuzorodza tsandanyama unoshandiswa. Kusanganiswa kweNeostigmine kazhinji hakudhuri uye kunowanikwa zvakanyanya, zvichiita kuti ive sarudzo dzinoshanda kune nzira zhinji.

Anesthesiologist wako achafunga nezvezvinhu zvakaita sebasa remapapu ako, hutano hwemoyo wako, uye kukurumidza kwekudzoserwa paanenge achisarudza pakati pezvisarudzo. Mishonga yese ine nzvimbo dzakakura dzekuchengetedza kana ichishandiswa zvakakodzera munzvimbo dzekurapa.

Mibvunzo Inowanzo Bvunzwa Nezve Neostigmine Methylsulfate uye Glycopyrrolate

Neostigmine Methylsulfate uye Glycopyrrolate Zvakachengeteka Here Kune Chirwere Chemoyo?

Mishonga iyi inogona kushandiswa zvakachengeteka kune vanhu vazhinji vane chirwere chemoyo, asi inoda kutariswa zvakanyanya uye dzimwe nguva kugadzirisa muyero. Chikamu cheglycopyrrolate chinobatsira kuchengetedza moyo wako nekudzivirira kumhanya kwemoyo kunonoka kunogona kukonzerwa ne neostigmine yega.

Anesthesiologist wako achatarisa mamiriro ako chaiwo emoyo uye mishonga iripo pamberi pekuvhiyiwa. Vanogona kusarudza dosing yakagadziridzwa kana dzimwe nzira kana uine matambudziko akakomba emoyo kana chirwere chemoyo chisina kugadzikana.

Ndoitei kana ndikashandisa Neostigmine Methylsulfate uye Glycopyrrolate zvakanyanya netsaona?

Haugone kuwandisa pamushonga uyu nekuti unongopihwa nevashandi vehutano munzvimbo dzekurapa dzakadzorwa. Dosing inoverengwa zvakanyanya uye inotungamirirwa nevapi veanesthesia vakadzidziswa vanotarisa mhinduro yako nguva dzose.

Kana mumwe munhu akagamuchira zvakanyanya, zviratidzo zvinogona kusanganisira kusimba kwetsandanyama, shanduko dzemoyo, kana matambudziko ekufema. Zvisinei, timu yako yekurapa yakashongedzerwa kuziva nekubata chero nyaya dzekuisa mushonga nekukasira nekuchengetwa kwakakodzera uye antidotes kana zvichidiwa.

Ndoitei kana ndikakanganwa muyero weNeostigmine Methylsulfate uye Glycopyrrolate?

Mubvunzo uyu haushande kumushonga uyu nekuti hautorwi panguva yakatarwa semishonga yezuva nezuva. Unoupiwa kamwe chete panguva yekuvhiwa kwako sechikamu chekutungamira anesthesia.

Chikwata chako cheanesthesia chinoona nguva chaiyo zvichienderana nekupindura kwemuviri wako kumishonga inozorodza mhasuru uye zvaunoda pakuvhiwa. Hapana chiitiko che“kurasikirwa nemushonga” nekuti mushonga unopiwa sechikamu chekutarisirwa kwako kwekurapa panguva yekuvhiwa.

Ndingamira Rini Kutora Neostigmine Methylsulfate uye Glycopyrrolate?

Haufaniri kunetseka nezvekumisa mushonga uyu nekuti jekiseni rimwe chete rinopiwa chete panguva yekuvhiwa. Mhedzisiro inopera zvakasikwa mukati memaminitsi makumi matatu kusvika makumi matanhatu, uye hapana kurapwa kuri kuenderera mberi kana maitiro ekubvisa.

Paunenge wapora kubva ku anesthesia uye simba remhasuru dzako radzoka kune zvakajairika, mushonga wakapedza basa rawo. Chikwata chako chekurapa chichasimbisa kuti uri kufema uye kufamba zvakajairika usati wabva kunzvimbo yekupora.

Ndingatyaira Mota Mushure meKugamuchira Neostigmine Methylsulfate uye Glycopyrrolate?

Haufaniri kutyaira kwemaawa makumi maviri nemana mushure mekuwana mushonga uyu, asi chipingamupinyi ichi chinonyanya kukonzerwa neanesthesia uye kuvhiwa panzvimbo yemushonga wekudzosa pachako. Mushonga unokubatsira kupora kubva ku anesthesia, asi uchiri kuda nguva yekuti mhedzisiro yese yeanesthetic ibvise zvachose sisitimu yako.

Chikwata chako chehutano chichapa mirairo chaiyo nezvekuti unogona riini kutangazve kutyaira uye zvimwe zviitiko zvakachengeteka. Nhungamiro idzi dzinofunga nezve rudzi rwekuvhiwa kwako, ruzivo rwese rweanesthesia, uye kufambira mberi kwemunhu mumwe nemumwe.