Chii chinonzi Oritavancin: Zvayinoshandiswa, Mishonga, Zvayakashata uye Zvimwe

Oritavancin mushonga une simba weantibiotic unopiwa kuburikidza nemutsara weIV (intravenous) kurapa zvirwere zvakakomba zvebhakitiriya paganda. Mushonga uyu ndewemukirasi itsva yeantibiotics inonzi lipoglycopeptides, iyo inoshanda zvakasiyana neakawanda maantibiotics echinyakare aunogona kuziva.

Chinonyanya kuita kuti oritavancin ive yakakosha ndeyekuti yakagadzirirwa semushonga wenguva imwe chete. Panzvimbo pokutora madosi akawanda kwemazuva akati wandei, unogamuchira infusion imwe chete inoramba ichishanda mumuviri wako kwevhiki. Iyi nzira inogona kubatsira kunyanya kana uchibata nezvirwere zvakaoma zvisina kupindura zvakanaka kune dzimwe nzira dzekurapa.

Chii chinonzi Oritavancin chinoshandiswa?

Oritavancin inorapa acute bacterial skin and skin structure infections (ABSSSI) muvanhu vakuru. Izvi zvirwere zvakakomba zvinopfuura pamusoro peganda rako uye zvinogona kubatanidza tishu, tsandanyama, kana mafuta ari pasi.

Chiremba wako angakurudzira oritavancin kana uine zvirwere zvinokonzerwa nemamwe mabhakitiriya, kusanganisira methicillin-resistant Staphylococcus aureus (MRSA). MRSA imhando yebhakitiriya isingapinduri kune akawanda maantibiotics akajairika, zvichiita kuti zvive zvakaoma kurapa. Oritavancin inoshandawo kune mamwe mabhakitiriya egram-positive anogona kukonzera zvirwere zvepaganda.

Mushonga uyu unowanzo chengeterwa mamiriro ezvinhu apo mamwe maantibiotics asina kushanda kana paunenge uine chirwere chakakomba chinoda kurapwa kwakanyanya. Mupi wako wehutano achasarudza kana oritavancin iri sarudzo chaiyo zvichienderana nehutachiona hwako chaihwo uye nhoroondo yekurapa.

Oritavancin inoshanda sei?

Oritavancin inoonekwa seantibiotic yakasimba inoshanda nekukanganisa nzira iyo mabhakitiriya anovaka masvingo avo ecell. Funga nezvemasvingo ecell ebhakitiriya semagamba anodzivirira anochengetedza mabhakitiriya ari mupenyu uye achishanda nemazvo.

Mishonga iyi inorwisa mabhakitiriya nenzira dzakawanda panguva imwe chete. Inodzivirira mabhakitiriya kubva pakugadzira zvinhu zvitsva zvemadziro esero uye inokuvadzawo madziro esero avanotova nawo. Chiito ichi chembiri chinoita kuti zvive zvakaoma kuti mabhakitiriya ararame uye abereke, zvichipa immune system yako mukana uri nani wekubvisa hutachiona.

Mishonga inoramba ichishanda mumuviri wako kwenguva yakareba mushure mekuiswa, ichiramba ichirwisa mabhakitiriya kwemazuva anenge manomwe. Chiito ichi chinoramba chiripo ndicho chikonzero nei uchida dose imwe chete pane kurapwa kwakawanda mumazuva akati wandei.

Ndingatora sei Oritavancin?

Oritavancin inopiwa chete kuburikidza neIV line muchipatara kana munzvimbo yekiriniki. Hauzotoreri mushonga uyu kumba kana nemuromo. Mushonga uyu unouya semupfu uyo vanachiremba vanosanganisa nemvura yakachena kuti vagadzire infusion.

Maitiro ekuisa anoda anenge maawa matatu. Chikwata chako chehutano chichakutarisa zvakanyanya panguva ino kuti chitarise chero maitiro. Iwe uchabatana neIV line, uye mushonga uchareruka zvishoma nezvishoma muropa rako.

Usati waiswa, haufanire kudzivisa chikafu kana zvinwiwa kunze kwekunge chiremba wako akupa mirairo chaiyo. Zvisinei, zvakakosha kuti uudze mupi wako wehutano nezve mishonga yese yauri kutora, sezvo imwe inogona kuita ne oritavancin.

Panguva yekuisa, ungangoda kugara munzvimbo imwe chete yechipatara kana kiriniki. Iwe unogona kazhinji kuverenga, kushandisa foni yako, kana kuita mabasa akanyarara apo mushonga uri kupihwa.

Ndingatora Oritavancin kwenguva yakareba sei?

Oritavancin yakagadzirirwa seimwe-dose kurapwa. Iwe uchagamuchira infusion imwe chete, uye ndizvo zvese zvaunowanzo kuda kuhutachiona hwako.

Mishonga inoenderera mberi ichishanda mumuviri wako kwemazuva anenge manomwe mushure mekuiswa. Iyi nguva yekuita yakawedzerwa yakavakwa mukuti mushonga unoshanda sei, saka haudi mamwe madosi sezvaungaita nemamwe maantibiotics mazhinji.

Chiremba wako achatarisa kufambira mberi kwako mumazuva anotevera nemavhiki kuti ave nechokwadi chekuti hutachiona huri kupora zvakanaka. Muzviitiko zvisingawanzoitiki, kana hutachiona husina kupindura zvakakwana, mupi wako wehutano angangofunga nezvekurapa kwakawedzerwa, asi izvi zvinogona kusanganisira nzira yakasiyana pane oritavancin yakawanda.

Ndezvipi Zvipingamupinyi zveOritavancin?

Semishonga yese, oritavancin inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Vanhu vazhinji vanotsungirira mushonga zvakanaka, asi zvakakosha kuziva zvekutarisa.

Heano mhedzisiro yakajairika yaungasangana nayo:

• Kutemwa nemusoro
• Nausea
• Kurwadziwa kwemaoko kana makumbo
• Dhayareya
• Mhinduro panzvimbo yeIV (kutsvuka, kuzvimba, kana kurwadziwa)

Mhedzisiro iyi inowanzoita nyoro uye inowanzoenda yega mukati memazuva mashoma. Chikwata chako chehutano chinogona kubatsira kubata chero kusagadzikana kwaunosangana nako.

Mhedzisiro yakakomba haina kujairika asi inoda kutariswa kwekurapa nekukurumidza. Izvi zvinogona kusanganisira mhinduro dzakakomba dzekurwara, dzinogona kukonzera matambudziko ekufema, kuzvimba kwechiso chako kana huro, kana rash yakapararira. Kana iwe ukasangana nechero zviratidzo izvi, tsvaga rubatsiro rwekurapa nekukurumidza.

Vamwe vanhu vanogona kukudziridza hutachiona hwakakomba hwematumbu hunonzi C. difficile-associated diarrhea (CDAD) panguva kana mushure mekurapa. Izvi zvinogona kuitika vhiki mushure mekutambira mushonga. Bata chiremba wako kana iwe ukasangana nedhayareya inoramba iripo, kunyanya kana iine ropa kana iine mucus.

Ndiani Asingafaniri Kutora Oritavancin?

Oritavancin haikodzeri munhu wese. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira kurapwa uku.

Haufanire kutambira oritavancin kana wakambove nemhinduro yekurwara kwairi munguva yakapfuura kana kumishonga inorwisa mabhakitiriya yakafanana sevancomycin kana telavancin. Udza mupi wako wehutano nezve chero allergy dzakapfuura dzemishonga inorwisa mabhakitiriya, kunyangwe dzaiita sedziri nyoro.

Vanhu vane zvirwere zvemwoyo vanoda kutariswa zvakakosha. Oritavancin inogona kukanganisa bvunzo dzekuvharika kweropa kwemahora anosvika 120 (mazuva mashanu) mushure mekurapwa. Kana uri kutora mishonga yekutetesa ropa yakaita se warfarin, chiremba wako achada kukutarisa zvakanyanya uye anogona kuda kugadzirisa mishonga yako.

Mishonga iyi haina kudzidzwa zvakanyanya muvakadzi vane pamuviri, saka chiremba wako achayerera mabhenefiti achipesana nenjodzi dzinogona kuitika kana une pamuviri kana kuronga kuva nepamuviri. Saizvozvowo, hazvizivikanwe kana oritavancin ichipinda mumukaka wemazamu, saka vanaamai vanoyamwisa vanoda gwara rakasiyana.

Zita reBrand reOritavancin

Oritavancin inotengeswa pasi pezita rebrand Orbactiv muUnited States. Iri ndiro zita rekutengesa rauchaona pamachati echipatara uye marekodhi ekurapa.

Mishonga iyi inogadzirwa neMelinta Therapeutics uye yakatenderwa neFDA muna 2014. Kana vapi vehutano vachitaura nezvekurapa uku, vanogona kushandisa zita re generic (oritavancin) kana zita rebrand (Orbactiv).

Zvimwe Zvingashandiswa Panzvimbo peOritavancin

Mamwe maantibayoti anogona kurapa zvirwere zvakafanana, asi chiremba wako achasarudza zvichienderana nemamiriro ako chaiwo uye mabhakitiriya ari kukonzera hutachiona hwako.

Vancomycin imwe nzira inowanzo shandiswa, kunyanya kune MRSA infections. Zvisinei, inoda madosi akawanda kwemazuva akati wandei panzvimbo yekushandisa dose imwechete ye oritavancin. Linezolid imwe sarudzo inogona kupiwa kuburikidza neIV kana nemuromo.

Kune dzimwe infections, daptomycin inogona kukodzera. Antibiotic iyi inopiwa kamwe chete pazuva kuburikidza neIV uye inoshanda kune akawanda emabhakitiriya akafanana ne oritavancin. Telavancin imwe antibiotic ye lipoglycopeptide yakafanana ne oritavancin asi inowanzoita kuti kudoserwa kwezuva nezuva.

Mupi wehutano hwako achafunga nezvezvinhu zvakaita sebhakitiriya chaiyo inobatanidzwa, kushanda kwematsvo ako, mamwe mishonga yaunotora, uye hutano hwako hwese paunenge uchisarudza mushonga wakanakisisa wekurwisa mabhakitiriya wemamiriro ako ezvinhu.

Ko Oritavancin Ari Nani Pane Vancomycin?

Ose ari maviri oritavancin ne vancomycin mishonga inoshanda yekurwisa mabhakitiriya akakomba, asi imwe neimwe ine zvainobatsira zvakasiyana zvichienderana nemamiriro ako ezvinhu.

Kubatsira kukuru kweOritavancin ndiko nyore. Unogamuchira jekiseni rimwe chete panzvimbo yemadosi akawanda kwemazuva akati wandei. Izvi zvinogona kubatsira kana uine dambudziko neIV access kana kana uchida kuderedza nguva yekuchipatara.

Vancomycin yanga ichishandiswa kwemakumi emakore uye ine chimiro chekuchengeteka chakagadzwa zvakanaka. Kazhinji haina kudhura kupfuura oritavancin uye inowanikwa munzvimbo dzakawanda dzehutano. Zvisinei, inoda kuongororwa kwemazinga eropa uye kushanda kwematsvo panguva yekurapa.

Zvidzidzo zvinoratidza kuti mishonga yese iri miviri inoshanda zvakafanana pakurapa zvirwere zvepaganda uye zvinyoro. Chiremba wako achafunga nezvezvinhu zvakaita sekushanda kwematsvo ako, mamwe mishonga, inishuwarenzi, uye zvaunofarira pachako paunenge uchisarudza kuti mushonga wakanakisisa wekurwisa mabhakitiriya ndewupi kwauri.

Mibvunzo Inowanzo Bvunzwa Nezve Oritavancin

Ko Oritavancin Akachengeteka Kuvanhu Vane Chirwere Chematsvo?

Oritavancin inoita seyakachengeteka kuvanhu vane matambudziko ematsvo kana ichienzaniswa nemamwe mishonga yekurwisa mabhakitiriya. Mushonga haudi kugadziriswa kwemadosi zvichienderana nekushanda kwematsvo, izvo zviri kubatsira pamishonga yekurwisa mabhakitiriya yakaita sevancomycin.

Zvisinei, chiremba wako achiri kuongorora kushanda kwematsvo ako usati watanga uye mushure mekurapa. Kana uine chirwere chakakomba chematsvo kana uri pa dialysis, mupi wako wehutano achanyatsoongorora kana oritavancin iri sarudzo yakakunakira.

Ndoita Sei Kana Ndine Allergy kuOritavancin?

Kana ukaona zviratidzo zvekuita allergic reaction panguva kana mushure mekuiswa kwemishonga yako, tsvaga rubatsiro rwekurapa nekukasira. Zviratidzo zvinosanganisira kuoma kufema, kuzvimba kwechiso chako kana pahuro, rash yakapararira, kana dzungu rakanyanya.

Sezvo iwe uchigamuchira oritavancin munzvimbo yekurapa, nyanzvi dzehutano dzichave dziripo nekukasira kuti dzirape chero maitiro. Vane mishonga nemidziyo yakagadzirira kubata allergic reactions nekukurumidza uye nemazvo.

Kana iwe ukaita delayed allergic reaction mushure mekubuda muchipatara, enda kuchipatara chepedyo kana kufonera 911. Usamirira kuti uone kana zviratidzo zvichivandudzika zvega.

Ndingaita Sei Kana Ndikakanganwa Dose yeOritavancin?

Mubvunzo uyu haushande ku oritavancin nekuti inopiwa sedose imwechete munzvimbo yekurapa. Hauzombokwanisi kukanganwa dose sezvo iwe uchigamuchira kurapwa kwese panguva yekushanya kumwechete kuchipatara.

Kana nekuda kwechimwe chikonzero kuisa kwako mishonga kukavhiringidzwa kana kumiswa nekukurumidza, timu yako yehutano ichasarudza nzira yakanakisa yekuita. Vanogona kupedzisa kuisa mishonga kana zvakachengeteka kuita kudaro kana kufunga nezvemamwe marapirwo.

Ndingamira Rini Kutora Oritavancin?

Haufanire kumira kutora oritavancin nekuti kurapwa kamwechete. Mushure mekuiswa kwako kamwechete, mushonga unoenderera mberi uchishanda mumuviri wako kwevhiki imwechete pasina mamwe madosi.

Chiremba wako achaita maapointments ekutevera kuti aongorore kupora kwako uye ave nechokwadi chekuti hutachiona huri kubviswa nemazvo. Ramba uchitora chero mamwe mishonga sezvakanyorwa kunze kwekunge chiremba wako akuudza zvimwe.

Ndingatyaira Here Mushure meKugamuchira Oritavancin?

Unofanira kudzivisa kutyaira nekukasira mushure mekuiswa kwako oritavancin, kunyanya kana uchinzwa dzungu, kuneta, kana kusanzwa zvakanaka. Maitiro ekuisa mishonga anotora maawa akati wandei, uye unogona kunzwa wakaneta mushure.

Kumbira mumwe munhu kuti akutyairire kumba mushure mekurapwa kwako, kana kuronga imwe nzira yekufamba. Vanhu vazhinji vanonzwa vakadzokera kune zvakajairika mukati mezuva rimwe kana maviri, asi teerera muviri wako uye usatyaira kana usinganzwe wakanyatsomuka uye wakatsiga.