Chii chinonzi Pretomanid: Zvazvinoshandiswa, Madosi, Migumisiro Yakaipa, nezvimwe

Pretomanid mushonga mutsva wemishonga inorwisa mabhakitiriya yakagadzirirwa kurapa mamwe marudzi etuberculosis (TB) asingapinduri zvakanaka kumishonga yakajairika. Inoshanda nekunangana nemabhakitiriya anokonzera TB nenzira yakasiyana, zvichiita kuti ive inokosha pakurapa mhando dzinodzivisa mishonga dzehutachiona hwe mapapu hunotyisa.

Mushonga uyu unomiririra kubudirira kukuru mukurapa TB, kunyanya kune vanhu vane hutachiona husina kuvandudzwa nemishonga inorwisa mabhakitiriya yechinyakare. Kunzwisisa kuti pretomanid inoshanda sei uye zvekutarisira zvinogona kukubatsira kuti unzwe wakavimbika nezvekufamba kwako kwekurapa.

Chii chinonzi Pretomanid?

Pretomanid ndeyemukirasi wemishonga inorwisa mabhakitiriya inonzi nitroimidazoles, iyo inoshanda zvakasiyana nemishonga yekare yeTB. Yakagadzirwa zvakananga kurwisa mabhakitiriya e tuberculosis akave achidzivisa kurapwa kwakawanda kwakajairika.

Mushonga unokanganisa kugona kwebhakitiriya kuvaka nekuchengetedza madziro avo emasero, zvichivaderedza kusvika vasingachagoni kurarama. Iyi nzira yakatarwa inoita kuti pretomanid ive inoshanda zvakanyanya pakurwisa hutachiona hweTB hunoomesa hunooma kubvisa nemimwe mishonga inorwisa mabhakitiriya.

Iwe unowanzo gamuchira pretomanid sechikamu chekurapa kwakabatanidzwa, zvinoreva kuti inoshanda pamwe chete nemimwe mishonga yeTB kugadzira nzira yekurapa ine simba. Iyi nzira yekubatanidza inobatsira kudzivirira mabhakitiriya kubva pakuvandudza kuramba kumushonga mumwe chete.

Pretomanid inoshandiswa nei?

Pretomanid inonyanya kushandiswa kurapa tuberculosis inodzivisa mishonga zvakanyanya (XDR-TB) uye mamwe mhosva ye multidrug-resistant tuberculosis (MDR-TB). Aya ndiwo marudzi akakomba eTB asingapinduri kumishonga yakajairika yekutanga.

Chiremba wako angaraira pretomanid kana uine fivhiri yemapapu - mhando inobata mapapu ako - uye kurapwa kwakamboitwa hakuna kubudirira. Inobvumirwa zvakananga kushandiswa pamwe chete nebedaquiline uye linezolid, ichigadzira zvinonzi BPaL regimen.

Mishonga iyi yakachengeterwa nyaya idzo dzimwe nzira dzekurapa dzakapera kana dzisina kukodzera. Chikwata chako chehutano chichanyatsoongorora mamiriro ako chaiwo kuti uone kana pretomanid iri sarudzo yakakodzera yekurapa TB yako.

Pretomanid Inoshanda Sei?

Pretomanid inoshanda nekukanganisa kugona kwebhakitiriya reTB kugadzira zvikamu zvakakosha zvavanoda kuti vararame. Inoonekwa semushonga unopesana nehutachiona wakasimba zvishoma uyo unotarisa mabhakitiriya eTB nenzira yakasiyana neyekare mishonga.

Mishonga inobatwa mukati mebhakitiriya reTB kuburikidza neenzymatic process chaiyo. Kana yaburitswa, inogadzira makomisheni ane chepfu anokuvadza DNA yebhakitiriya uye anokanganisa kugadzirwa kwavo kwesimba, pakupedzisira zvichitungamira kurufu rwavo.

Chinonyanya kukosha pretomanid kugona kwayo kushanda pamabhakitiriya ari kukura uye ayo akavanda anogona kunge akavanda mumuviri wako. Iyi chiito chepamusoro inobatsira kuona kurapwa kwakakwana kwehutachiona hwako hweTB.

Ndinofanira Kutora Sei Pretomanid?

Unofanira kutora pretomanid sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva nechikafu. Kuitora nechikafu kunobatsira muviri wako kutora mishonga zvakanyanya uye kunogona kuderedza mukana wekugumbuka mudumbu.

Zvakanakisa kutora pretomanid panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana mumuviri wako. Unogona kuitora nemvura, mukaka, kana muto - chero zvinoita sekunyaradza kwauri. Kunge snack yakareruka kana chikafu pamberi zvinokurudzirwa.

Dzivisa kutora pretomanid mudumbu risina chinhu, sezvo izvi zvinogona kuwedzera njodzi yekunzwa kusvotwa uye zvinogona kukanganisa kuti muviri wako unotora sei mushonga. Kana uine kusagadzikana mudumbu, edza kutora nemukaka mukuru kana kutaura nachiremba wako nezvekugadzirisa nguva.

Ndingatora Pretomanid Kwenguva Yakareba Sei?

Nzira yekurapa inowanzoitwa nepretomanid inotora mwedzi mitanhatu, kunyangwe chiremba wako achaziva nguva chaiyo zvichienderana nemamiriro ako chaiwo uye mhinduro kumushonga. Izvi zvakanyanya kupfupika kupfuura kurapwa kweTB yechinyakare, iyo inowanzoita mwedzi gumi nemasere-24.

Vashandi vehutano vachatarisa kufambira mberi kwako kuburikidza nekutarisa nguva dzose, bvunzo dzeropa, uye zvidzidzo zvekuona kuti vave nechokwadi chekuti mushonga uri kushanda nemazvo. Vanogona kugadzirisa urefu hwekurapa kana zvichidikanwa zvichienderana nekuti muviri wako unopindura sei.

Zvakakosha kupedzisa nzira yese yekurapa, kunyangwe ukatanga kunzwa zviri nani usati wapedza mishonga yese. Kumira kare kunogona kubvumira mabhakitiriya eTB kudzoka uye anogona kukudziridza kuramba kumishonga.

Ndezvipi Zvipingamupinyi zvePretomanid?

Semishonga yese, pretomanid inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Kunzwisisa zvekutarisa kunogona kukubatsira kubata chero nyaya dzinomuka uye kuziva nguva yekubata chiremba wako.

Mhedzisiro yakajairika inowanzoita manejimendi uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Heano mhedzisiro yaunonyanya kusangana nayo:

• Kusvotwa uye kurutsa, kunyanya mumavhiki mashoma ekutanga
• Kurasikirwa nechido kana shanduko mukuravira
• Kuneta uye kuneta kwese
• Kutemwa nemusoro
• Dhiria kana kusagadzikana mudumbu
• Dizziness kana lightheadedness

Zviratidzo izvi zvinowanzoita zvishoma sezvo muviri wako uchigadzirisa kurapwa. Kutora mushonga nechikafu uye kugara uine hydrated kunogona kubatsira kuderedza mhedzisiro iyi.

Vamwe vanhu vanogona kusangana nemigumisiro yakakomba inoda kutariswa kwechimbichimbi kwekurapa. Kunyange izvi zvisingawanzoitiki, zvakakosha kuziva nezvazvo:

• Kunyara kwakanyanya kana kurutsa kunokutadzisa kuchengeta chikafu kana zvinwiwa pasi
• Zviratidzo zvematambudziko echiropa, zvakadai sekusviba kweganda kana maziso, weti yakasviba, kana kurwadziwa kwakanyanya mudumbu
• Kubuda ropa kusinganzwisisike kana kupwanya
• Kurwadziwa kwemusoro kwakanyanya nekuchinja kwekuona
• Kufema kwakaoma kana kurwadziwa muchipfuva
• Kuita kweganda kwakanyanya kana mapundu

Kana iwe ukasangana nechero zviratidzo izvi zvakakomba, taura nemupi wako wehutano nekukurumidza kana kutsvaga rubatsiro rwekurapa rwechimbichimbi. Kupindira kwekutanga kunogona kudzivirira matambudziko uye kuona kuchengeteka kwako.

Ndiani Asingafaniri Kutora Pretomanid?

Pretomanid haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wairaira. Mamiriro akati wandei uye mamiriro anogona kuita kuti mushonga uyu usakodzere kana kuda matanho akakosha.

Haufaniri kutora pretomanid kana iwe uchiziva allergy kumishonga ye nitroimidazole kana chero zvinhu zviri mumapiritsi epretomanid. Mupi wako wehutano achakurukura dzimwe nzira dzekurapa kana iwe uine izvi allergies.

Mamiriro akati wandei ehutano anoda kufungwa zvakanyanya usati watanga kurapwa kwepretomanid:

• Chirwere chechiropa chakakomba kana nhoroondo yematambudziko echiropa
• Chirwere cheitsvo chakakomba chinoda dialysis
• Kuzvitakura kana zvirongwa zvekuva nepamuviri
• Kuyamwisa
• Vana vari pasi pemakore gumi nemana
• Matambudziko akakomba emoyo

Chiremba wako achayerera mabhenefiti achipesana nenjodzi dzinogona kuitika mumamiriro ako chaiwo. Vanogona kukurudzira kuongorora kwakawedzerwa kana dzimwe nzira dzekurapa kana iwe uine chero mamiriro aya.

Mazita ePretomanid Brand

Pretomanid inowanikwa pasi pezita rekuti Pretomanid FGK, iyo inogadzirwa neFGK Representative Service LLC. Iri ndiro zita guru riripo mumisika yakawanda uko mushonga uyu unobvumirwa.

Mushonga uyu unogonawo kutaurwa nezita rawo rekuti pretomanid, mumabhuku ekurapa uye mapepa ekurapa. Kambani yako yemishonga inowanzo kukupa zita remushonga riripo munzvimbo yako.

Nguva dzose ongorora nemushonga wako kuti uri kuwana mushonga wakarurama, uye usachinje pakati pemishonga yakasiyana pasina kutanga wabvunza chiremba wako.

Zvimwe Zvinogona Kushandiswa Panzvimbo pePretomanid

Kana pretomanid isingakukodzere, kune nzira dzakawanda dzekurapa fivhiri yeTB isingaporeswe nemishonga. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nerudzi rweTB yako uye nhoroondo yako yekurapa.

Mishonga mitsva yeTB inogona kufungwawo inosanganisira bedaquiline, delamanid, kana linezolid, inowanzo shandiswa pamwe chete. Mishonga iyi inoshanda nenzira dzakasiyana asi inogona kushanda kurwisa mhando dzeTB dzisingaporeswe nemishonga.

Mishonga yechinyakare yeTB yechipiri yakaita sefluoroquinolones, maantibayoti anojekeswa, kana mimwe mishonga yemumuromo inogonawo kuva sarudzo, zvichienderana nekuti mabhakitiriya ako eTB anoramba sei mishonga. Chikwata chako chehutano chichaita bvunzo yekuti chione kuti ndedzipi mishonga dzinonyanya kushanda pakurapa hutachiona hwako.

Pretomanid iri Nani Kudarika Rifampin Here?

Pretomanid na rifampin vanoshanda zvakasiyana mukurapa TB, saka hazvina kururama kutaura kuti imwe iri "nani" pane imwe. Rifampin ndiyo hwaro hwekurapa TB kwakajairika, nepo pretomanid yakagadzirirwa zvakananga kesi dzisingaporeswe nemishonga.

Kana TB yako ichinzwisisa rifampin, chiremba wako anogona kusarudza kurapwa kunobva pa rifampin nekuti yakanyatsojeka, inoshanda, uye ine makumi emakore edata rekuchengeteka. Rifampin inoshanda zvakanyanya kune TB inonzwa kumishonga uye inowanzo sarudzwa kana ichishanda.

Pretomanid inova sarudzo iri nani kana rifampin nemimwe mishonga yakajairika isingashande kana uine TB inodzivirira mishonga. Inopa nguva pfupi yekurapa uye inogona kushanda kune mhando dzisingapinduri kune rifampin-based regimens.

Mibvunzo Inowanzo Bvunzwa Nezve Pretomanid

Pretomanid Yakachengeteka Kune Vanhu vane Chirwere cheShuga here?

Pretomanid inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheshuga, asi inoda kunyatsoongororwa. Mushonga hauna zvakananga mazinga eshuga yeropa, asi hutachiona hweTB pachahwo hunogona kuita kuti manejimendi echirwere cheshuga ave nematambudziko.

Chikwata chako chehutano chichashanda pedyo newe kuti chiongorore mhinduro yako yekurapa TB uye kudzora shuga yeropa. Vanogona kuda kugadzirisa mishonga yako yechirwere cheshuga kana chirongwa chekuongorora iwe uri pakurapa pretomanid.

Ndingaita Sei Kana Ndikatora Pretomanid yakawandisa netsaona?

Kana netsaona ukatora pretomanid yakawanda kupfuura yakarairwa, taura nemupi wako wehutano kana nzvimbo yekudzora muchetura nekukasira. Usamirira kuti uone kana zviratidzo zvichivapo - zano rekurapa nekukurumidza rakakosha.

Paunenge uchimirira gwara rekurapa, dzivisa kutora mimwe mishonga uye gara uine mvura yakawanda. Iva nebhodhoro rako remishonga kuti ugone kupa ruzivo rwechokwadi nezvechawakatora uye yakawanda sei.

Ndingaita Sei Kana Ndikarasikirwa neDose yePretomanid?

Kana ukakanganwa dose ye pretomanid, itore paunorangarira, chero zvisiri pedyo nenguva yekutora dose yako inotevera. Kana iri pedyo nenguva yako inotevera, siya dose yakarasika uye uenderere mberi nechirongwa chako chese.

Usambofa wakatora zvikamu zviviri panguva imwe chete kuti ugadzirise chikamu chakasiiwa, sezvo izvi zvinogona kuwedzera njodzi yako yezvinhu zvisingadiwi. Bata chiremba wako kana uchikanganwa kazhinji zvikamu - vanogona kukubatsira kugadzira nzira dzekuramba uri munzira.

Ndingamira Rini Kutora Pretomanid?

Unofanira kungomira kutora pretomanid kana chiremba wako akuudza kuti zvakachengeteka kuita kudaro, kazhinji mushure mekupedza mwedzi mitanhatu yakazara. Kumira kare kunogona kubvumira mabhakitiriya eTB kudzoka uye pamwe kugadzira kuramba.

Chikwata chako chekuchengetwa kwehutano chichashandisa bvunzo dzakasiyana-siyana, kusanganisira tsika dzesputum uye zvidzidzo zvekuona, kuti zviwane kana kurapwa kwako kwapera. Kunyangwe iwe uchinzwa zvakanaka zvachose, ramba uchitora mushonga kusvikira chiremba wako asimbisa kuti inguva yekumira.

Ndinganwa Doro Here Ndichitora Pretomanid?

Zvakanaka kudzivisa doro uchitora pretomanid, sezvo mushonga nedoro zvinogona kukanganisa chiropa chako. Kuzvibatanidza zvinogona kuwedzera njodzi yako yezvinhu zvisingadiwi zvine chekuita nechiropa.

Kana ukasarudza kunwa dzimwe nguva, taura izvi nechiremba wako kutanga. Vanogona kukupa zano pamiganhu yakachengeteka uye vanogona kukurudzira kuongororwa kwechiropa kakawanda panguva yekurapa kwako.