Chii chinonzi Rimabotulinumtoxinb: Zvinoshandiswa, Mishonga, Mativi Emuviri, nezvimwe

Rimabotulinumtoxinb mushonga unotorwa nemishonga une botulinum toxin type B, protein yakacheneswa inozorora tsandanyama dzakawandisa kwenguva pfupi. Ungazviziva zviri nani nezita rayo remhando, Myobloc, uye ndeyemhuri imwechete yemishonga seBotox, kunyangwe ichishandisa imwe mhando ye botulinum toxin.

Mushonga uyu unoshanda nekudzivisa zviratidzo zvevhavha zvinoudza tsandanyama dzako kuti dzibatanidze. Kana yakajekeswa zvakananga mutsandanyama dzakatarwa, inopa zororo kubva kumaspasm etsandanyama anorwadza uye inogona kubatsira kuderedza kutukwa kwakanyanya mune dzimwe nzvimbo dzemuviri wako.

Chii chinonzi Rimabotulinumtoxinb chinoshandiswa?

Rimabotulinumtoxinb inorapa cervical dystonia, mamiriro ekuongorora uropi uko tsandanyama dziri mumutsipa wako nemapfudzi dzinobatanidza zvisina kufanira. Mamiriro aya anoita kuti musoro wako utendeuke kana kutendeukira munzvimbo dzisina kugadzikana, kazhinji zvichiperekedzwa nekurwadziwa kukuru uye kuoma kuita mabasa ezuva nezuva.

Mushonga uyu unotenderwawo kurapa kutukwa kwakanyanya kwemumawoko (axillary hyperhidrosis) kana dzimwe nzira dzisina kushanda zvakanaka. Chiremba wako angatarisa kurapwa uku kana maantiperspirants enguva dzose, mishonga yemishonga, kana dzimwe nzira dzisina kupa zororo rakakwana.

Dzimwe nguva, vanopa hutano vanoshandisa rimabotulinumtoxinb kune mamwe mamiriro ane hukama netsandanyama, kunyangwe izvi zvichizoonekwa sekushandiswa kunze kwemavara. Chiremba wako achakurukura kana mushonga uyu wakakodzera mamiriro ako chaiwo uye zviratidzo.

Rimabotulinumtoxinb inoshanda sei?

Rimabotulinumtoxinb inoshanda nekudzivisa kwenguva pfupi kuburitswa kwe acetylcholine, mutumwa wemakemikari anoudza tsandanyama dzako kuti dzibatanidze. Funga nezvazvo sekubvisa kwenguva pfupi mutsetse wekutaurirana pakati pemitsipa yako netsandanyama.

Mushonga uyu unoonekwa seune simba zvishoma uye wakanyatsotarwa. Kusiyana nemishonga inotorwa nemuromo inokanganisa muviri wako wese, rimabotulinumtoxinb inongokanganisa tsandanyama dzakanyatsojeka dzinenge dzichibaiwa, izvo zvinobatsira kuderedza mhedzisiro isingadiwi mune dzimwe nhengo dzemuviri wako.

Mhedzisiro yacho inowanzo kutanga mukati memazuva mashoma kusvika kumavhiki maviri mushure mejekiseni uye inogona kugara chero kupi kubva pamwedzi mitatu kusvika mitanhatu. Sezvo mushonga uchipera zvishoma nezvishoma, kutaurirana kwetsinga kunodzoka zvishoma nezvishoma, uye basa retsandanyama rinotangazve maitiro ayo ekutanga.

Ndingatora Sei Rimabotulinumtoxinb?

Rimabotulinumtoxinb inogara ichipiwa sejekiseni zvakananga mutsandanyama dzakakanganiswa nachiremba ane hunyanzvi. Hauzotorere mushonga uyu kumba kana nemuromo - zvinoda kutarisirwa nenyanzvi munzvimbo yekurapa.

Usati waenda kunoita jekiseni, haufanirwe kutsanya kana kudzivisa kudya, kunyangwe vamwe vanachiremba vachikurudzira kudzivisa doro kwemaawa makumi maviri nemana zvisati zvaitika. Unogona kudya zvakajairika uye kutora mishonga yako yenguva dzose kunze kwekunge chiremba wako akakuudza zvakasiyana.

Maitiro ejekiseni anowanzo tora maminitsi gumi nemashanu kusvika makumi matatu, zvichienderana nekuti tsandanyama ngapi dzinoda kurapwa. Chiremba wako achashandisa tsono diki kubaya mushonga munzvimbo dzakanyatsojeka patsandanyama dzakakanganiswa, achitungamirirwa neruzivo rwavo rwe anatomy uye dzimwe nguva vachibatsirwa nekukurudzira kwemagetsi kuti vawane nzvimbo dzakakodzera.

Mushure mejekiseni, unogona kazhinji kudzokera kuzviitiko zvako zvenguva dzose nekukasira. Zvisinei, chiremba wako anogona kukurudzira kudzivisa kurovedza muviri zvakanyanya kana kurara pasi kwemaawa mashoma kuti ubatsire mushonga kugara mutsandanyama dzakatarirwa.

Ndingatora Rimabotulinumtoxinb Kwenguva Yakareba Sei?

Mhedzisiro ye rimabotulinumtoxinb ndeyenguva pfupi, saka uchada majekiseni ekudzokorora kuti uchengetedze mabhenefiti. Vanhu vazhinji vanogamuchira majekiseni mwedzi mitatu kana mina yega yega, kunyangwe chirongwa chako chakanyatsojeka zvichienderana nekuti muviri wako unopindura sei kumushonga.

Vamwe vanhu vanowana zviratidzo zvavo zvichidzoka zvishoma nezvishoma mumwedzi yakati wandei, asi vamwe vanoona kudzoka kamwe kamwe kwezvikamu zvemuviri kana kutukutira. Chiremba wako achashanda newe kuti awane nguva yakakodzera yekudzoka kwemajekiseni ako zvichienderana nekuti zviratidzo zvako zvinotanga riini kudzoka.

Hapana zuva rekupedzisira rakatarwa rekuti kurapwa uku kupera. Vanhu vazhinji vanoenderera mberi vachiwana majekiseni kwemakore sechikamu chekugadzirisa mamiriro avo echronic. Chiremba wako achagara achiongorora kana mushonga uyu uchiri kushanda uye wakachengeteka kumamiriro ako ega ega.

Ndezvipi Zvakaipa ZveRimabotulinumtoxinb?

Vanhu vazhinji vanotsungirira rimabotulinumtoxinb zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Mhedzisiro inowanzoitika inowanzoita nyoro uye yenguva pfupi, ichiitika panzvimbo yekujekiseni kana padyo.

Heano mhedzisiro yaungasangana nayo, kutanga neayo anowanzoitika:

• Kurwadziwa, kupwanya, kana kuzvimba panzvimbo yekujekiseni
• Kutemwa nemusoro kunogona kutora mazuva mashoma
• Zviratidzo zvakaita sefuruu zvinosanganisira fivha nyoro kana kurwadziwa kwemuviri
• Kushaya simba kwenguva pfupi mumhasuru dzakajekeswa
• Muromo wakaoma, unogona kuoneka zvakanyanya nemajekiseni emutsipa
• Kutadza kumedza (dysphagia) kana kurapa mhasuru dzemutsipa

Izvi zvinowanzoitika zvinowanzoenda mukati memazuva mashoma kusvika kumavhiki uye kazhinji hazvidi kurapwa kwekurapa kunze kwematanho ekunyaradza.

Mhedzisiro isingawanzoitiki asi yakakomba inogona kuitika, kunyangwe ichikanganisa vanhu vashoma vanopfuura 5% vanogamuchira mushonga uyu:

• Kutadza kukuru kumedza kana kufema
• Kushaya simba kwemhasuru kwakapararira kupfuura nzvimbo yekujekiseni
• Kuchinja kwechiratidzo kana kuona zvakapetwa kaviri
• Maitiro akakomba ekugadzirisa muviri anosanganisira rash, kukwenya, kana kuzvimba
• Kutadza kutaura kana kuchinja kwezwi

Kana iwe ukasangana neimwe yeiyi mhedzisiro yakakomba, taura nemupi wako wehutano nekukasika kana kutsvaga rubatsiro rwekurapa rwechimbichimbi.

Muzviitiko zvisingawanzoitiki, botulinum toxin inogona kupararira kupfuura nzvimbo yekujekesa uye kukonzera zviratidzo zvakaita sebotulism mumuviri wako wese. Izvi zvinoitika muvanhu vasingasviki 1% uye zvinosanganisira zviratidzo zvakaita sekushaya simba kwemhasuru, kuoma kufema, kana matambudziko ekuona nekutaura. Kunyange zvazvo izvi zvisingawanzoitiki, zvakakosha kuti utarise zviratidzo izvi uye utsvake rubatsiro rwekurapa nekukasira kana zvikaonekwa.

Ndiani Asingafaniri Kutora Rimabotulinumtoxinb?

Rimabotulinumtoxinb haina kuchengeteka kune munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira kurapwa uku. Hauzofaniri kugamuchira mushonga uyu kana uine allergic ku botulinum toxin kana chero zvinhu zviri mumushonga.

Mamwe mamiriro ekurapa anoita kuti rimabotulinumtoxinb ive njodzi. Chiremba wako anogona kukurudzira kurwisa kurapwa uku kana uine:

• Kutapukirwa kunoshanda panzvimbo yekujekesa yakarongwa
• Zvirwere zveNeuromuscular zvakaita se myasthenia gravis kana Lambert-Eaton syndrome
• Zvirwere zvekubuda ropa kana kana uri kutora mishonga yekutapudza ropa
• Matambudziko akakomba ekufema kana kuoma kumedza

Kuzvitakura nekuyamwisa zvinoda kufunga kwakakosha. Kunyange zvazvo pasina humbowo hwakajeka hwekuti rimabotulinumtoxinb inokuvadza vana vari kukura, vanachiremba vanowanzo kurudzira kuizvidza panguva yekuzvitakura kunze kwekunge mabhenefiti achipfuura njodzi.

Kana iwe uri kutora mishonga yakati wandei, chiremba wako angangoda kugadzirisa chirongwa chako chekurapa. Antibiotics senge aminoglycosides, muscle relaxants, uye mamwe mamwe mishonga anogona kuita ne rimabotulinumtoxinb uye kuwedzera njodzi yemigumisiro.

Rimabotulinumtoxinb Mazita eBrand

Zita remhando ye rimabotulinumtoxinb ndeye Myobloc, inogadzirwa neSolstice Neurosciences. Iri ndiro chete zita remhando ye rimabotulinumtoxinb inowanikwa mumabhizinesi muUnited States.

Myobloc inouya mumavhiri ekushandisa kamwechete ane mhando dzakasiyana dzemishonga. Chiremba wako achasarudza simba rakakodzera zvichienderana nemamiriro ako chaiwo uye tsandanyama dziri kurapwa.

Kusiyana nemamwe marudzi emishonga ye botulinum toxin, Myobloc haidi kugadziriswa kana kusanganiswa isati yashandiswa. Inouya yakagadzirira kujekesa, izvo zvinogona kuita kuti maitiro ekugadzirira ave nyore kune vanopa hutano.

Zvimwe Zvingashandiswa Panzvimbo peRimabotulinumtoxinb

Mamwe marudzi emishonga ye botulinum toxin anowanikwa kana rimabotulinumtoxinb isina kukodzera kwauri. Imwe nzira inozivikanwa zvakanyanya ndeye onabotulinumtoxinA (Botox), iyo inoshandisa botulinum toxin mhando A panzvimbo ye mhando B.

Zvimwe zvinogadzirwa zve botulinum toxin mhando A zvinosanganisira abobotulinumtoxinA (Dysport) uye incobotulinumtoxinA (Xeomin). Nepo mishonga iyi ichishanda zvakafanana ne rimabotulinumtoxinb, vane mafomula akasiyana uye vanogona kushanda zvakanyanya kana zvishoma kune vamwe vanhu.

Kune dzimwe nzira dzisiri dze botulinum toxin, sarudzo dzako dzekurapa dzinoenderana nemamiriro ako chaiwo. Cervical dystonia inogona kurapwa nemishonga yemuromo senge muscle relaxants, anti-seizure drugs, kana kunyangwe maitiro ekuvhiya mumatambudziko akakomba. Kufashukirwa zvakanyanya dzimwe nguva kunogona kutariswa nemishonga yekurapa, mishonga yemuromo, kana maitiro senge miraDry.

Chiremba wako achakubatsira kuongorora dzimwe nzira idzi kana rimabotulinumtoxinb isingape zororo rakakwana kana kana iwe ukawana mhedzisiro isingagamuchirwe.

Ko Rimabotulinumtoxinb Zviri Nani Pane Botox?

Kana rimabotulinumtoxinb iri nani pane Botox zvinoenderana nekupindura kwako kwega uye mamiriro ako chaiwo ekurapa. Mishonga yese iri miviri inoshanda botulinum toxin zvigadzirwa, asi vanoshandisa mhando dzakasiyana dzemishonga uye vanogona kushanda zvakasiyana mumuviri wako.

Vamwe vanhu vanopindura zviri nani ku rimabotulinumtoxinb (rudzi B toxin) kupfuura ku Botox (rudzi A toxin), kunyanya kana vakagadzira kusadzivirirwa kurudzi A zvigadzirwa. Kutanga kwechiito chingasiana zvishoma, nevamwe vanhu vachiona mhedzisiro nekukurumidza nechigadzirwa chimwe vachienzanisa nechimwe.

Kune cervical dystonia kunyanya, mishonga yese yakaratidza kushanda zvakafanana muzvidzidzo zvekiriniki. Sarudzo inowanzouya pasi pekupindura kwako kwega, ruzivo rwechiremba wako nechigadzirwa chimwe nechimwe, uye zvekufunga zvinoshanda semutengo uye inishuwarenzi.

Chiremba wako anogona kukubatsira kunzwisisa kuti ndechipi chisarudzo chingave chakanakira mamiriro ako, uye unogona kunyangwe kuyedza zvigadzirwa zvese panguva dzakasiyana kuti uone kuti ndeupi unoshanda zviri nani kwauri.

Mibvunzo Inowanzo Bvunzwa Nezve Rimabotulinumtoxinb

Rimabotulinumtoxinb Yakachengeteka Kune Vanhu vane Chirwere cheShuga Here?

Rimabotulinumtoxinb inowanzo chengeteka kune vanhu vane chirwere cheshuga, uye kuva nechirwere cheshuga hakukudzivisi otomatiki kubva pakugamuchira kurapwa uku. Zvisinei, chiremba wako achada kuona kuti chirwere chako cheshuga chinodzorwa zvakanaka usati waenderera mberi nekujekesa.

Vanhu vane chirwere cheshuga vanogona kuva nenjodzi yakakwira yekutapukirwa kana kupora zvishoma panzvimbo dzekujekesa, saka mupi wako wehutano angatora matanho ekuwedzera. Vanogona zvakare kukutarisa zvakanyanya mushure mejekiseni kuti vatarise chero maitiro asingawanzoitiki.

Ndoita Sei Kana Ndikashandisa Rimabotulinumtoxinb yakawandisa netsaona?

Sezvo rimabotulinumtoxinb inongopihwa nenyanzvi dzehutano, kuwandisa netsaona hakuiti. Zvisinei, kana ukagamuchira mushonga wakawandisa, kunetseka kukuru kungava kusimba kwemhasuru kwakanyanya kana kupararira kwemhedzisiro kumhasuru dzaisatarisirwa kurapwa.

Kana ukaona kusimba kwemhasuru kusinganzwisisiki, kuoma kufema, kana matambudziko ekumedza mushure mejekiseni, taura nachiremba wako nekukasira kana kutsvaga rubatsiro rwekurumidza. Izvi zvinogona kunge zviri zviratidzo zvekuti mushonga wakanganisa mhasuru dzakawanda kupfuura zvaitarisirwa.

Hapana mushonga chaiwo we rimabotulinumtoxinb, saka kurapwa kwaizotarisa pakugadzirisa zviratidzo uye kupa rutsigiro rwekutarisira apo mhedzisiro yemushonga inopera zvishoma nezvishoma mumwedzi yakati wandei.

Ndoita Sei Kana Ndikakanganwa Dose yeRimabotulinumtoxinb?

Kana ukakanganwa kugadzwa kwejekiseni, taura nemupi wehutano wako kuti ugadzirise zvakare nekukasira. Nguva yejekiseni rako rinotevera zvinoenderana nekuti zviratidzo zvako zvinodzoka riini uye kuti zvakatora nguva yakareba sei kubva pakurapwa kwako kwekupedzisira.

Unogona kuona mhasuru dzako dzichidedera kana kutukwa kwakanyanya kuchidzoka zvishoma nezvishoma sezvo mhedzisiro yejekiseni yapfuura. Izvi zvakajairika uye zvinotarisirwa, uye kuwana jekiseni rako rinotevera richabatsira kudzorera kutonga kwezviratidzo.

Usaedze kutsiva madosi akakanganwa nekugamuchira mushonga wakawanda pagadzwa rako rinotevera. Chiremba wako achasarudza dose yakakodzera zvichienderana nezviratidzo zvako zvazvino uye kuti zvakatora nguva yakareba sei kubva pajekiseni rako rekupedzisira.

Ndingamira Rini Kutora Rimabotulinumtoxinb?

Unogona kumira kugamuchira majekiseni e rimabotulinumtoxinb chero nguva, uye hapana zviratidzo zvekubvisa kana mhedzisiro ine njodzi yekurega mushonga. Zvisinei, zviratidzo zvako zvepakutanga zvichadzoka zvishoma nezvishoma sezvo mhedzisiro yemushonga inopera mumwedzi yakati wandei.

Vamwe vanhu vanosarudza kumisa kurapwa kana mamiriro avo ari nani, kana vakagadzira mhedzisiro isingagamuchirwi, kana kana vakawana dzimwe nzira dzekurapa dzinoshanda zviri nani kwavari. Vamwe vanogona kutora zororo kubva mukurapwa kuti vaone kuti zviratidzo zvavo zvachinja sei nekufamba kwenguva.

Usati wamisa kurapwa, kurukurai chisarudzo chenyu nachiremba wenyu. Vanogona kukubatsira kunzwisisa zvokutarisira sezvo mushonga uchipera uye vanogona kukurudzira mamwe marapirwo kana zvichidikanwa.

Ndingaita Maekisesa Mushure meKuwaniswa Majekiseni eRimabotulinumtoxinb here?

Vazhinji vanachiremba vanokurudzira kudzivisa maekisesa akaoma kwemaawa mashoma ekutanga mushure mekuwaniswa majekiseni e rimabotulinumtoxinb. Chenjedzo iyi inobatsira kuona kuti mushonga unogara mumhasuru dzakatarirwa panzvimbo yekupararira kunzvimbo dziri pedyo.

Mabasa akareruka sekufamba anowanzoita zvakanaka mushure mekusangana kwako kwejekiseni. Unogona kazhinji kudzokera kune yako yakajairika maekisesa zuva mushure mejekiseni ako, kunyangwe iwe uchifanira kuteerera muviri wako uye kudzivisa mabasa anokonzera kurwadziwa panzvimbo dzekujekiseni.

Kana iwe uchigamuchira majekiseni e cervical dystonia, chenjerera zvakanyanya nemaekisesa anosanganisira mutsipa wako nemhasuru dzemapfudzi kusvikira iwe uchiziva kuti mushonga unokukanganisa sei. Chiremba wako anogona kupa gwara rakatarwa zvichienderana nekuti ndedzipi mhasuru dzakabatwa uye mamiriro ako ega.