Chii chinonzi Sitagliptin: Zvayakashandiswa, Madosi, Migumisiro Yakaipa nezvimwe

Sitagliptin mushonga unopiwa nachiremba unobatsira kutarisira chirwere cheshuga che mhando 2 nekuchengeta mazinga eshuga yeropa rako ari muchiyero chakanaka. Iwo ndewe boka remishonga rinonzi DPP-4 inhibitors, iyo inoshanda zvinyoro nyoro nemaitiro emuviri wako echisikigo kuti uvandudze kutonga kweshuga yeropa pasina kukonzera kudonha kukuru.

Mushonga uyu wave sarudzo yakavimbika kune vanhu vazhinji vane chirwere cheshuga nekuti kazhinji inotsungirirwa zvakanaka uye inogona kushandiswa yega kana pamwe chete nemamwe marapirwo echirwere cheshuga. Kunzwisisa kuti sitagliptin inoshanda sei uye zvekutarisira zvinogona kukubatsira kuti unzwe wakavimbika nezve chirongwa chako chekutungamira chirwere cheshuga.

Chii chinonzi Sitagliptin?

Sitagliptin mushonga wechirwere cheshuga wemuromo unobatsira muviri wako kutarisira zviri nani mazinga eshuga yeropa zuva rese. Inoshanda nekudzivisa enzyme inonzi DPP-4, iyo inobvumira muviri wako kuti ubudise insulin yakawanda paunoida uye glucose shoma pausingade.

Funga nezve sitagliptin semubatsiri anobatsira anogadzirisa sisitimu yako yekudzora shuga yeropa. Kusiyana nemamwe mishonga yechirwere cheshuga inogona kukonzera kuti shuga yeropa rako idonhe zvakanyanya, sitagliptin yakagadzirirwa kushanda chete kana shuga yeropa rako yakakwira, zvichiita kuti ive sarudzo yakapfava kune vanhu vazhinji.

Mushonga uyu unowanikwa setableti yaunotora nemuromo, kazhinji kamwe chete pazuva. Inowanzo kurairwa kana kudya uye kurovedza muviri zvoga zvisina kukwana kuchengeta mazinga eshuga yeropa paanofanira kuva, kana kana mamwe mishonga yechirwere cheshuga ichida rubatsiro rwekuwedzera.

Sitagliptin Inoshandiswa Kunei?

Sitagliptin inonyanya kushandiswa kurapa chirwere cheshuga che mhando 2 muvanhu vakuru. Inobatsira kuderedza mazinga eshuga yeropa kana akakwira zvakanyanya, izvo zvinogona kudzivirira kusagadzikana nekukurumidza uye matambudziko enguva refu echirwere cheshuga.

Chiremba wako angakurudzira sitagliptin kana uchangobva kuwanikwa uine chirwere cheshuga che mhando 2 uye shanduko dzemaitiro ehupenyu hadzina kukwana kudzora shuga yako yeropa. Inowanzo wedzerwawo kune zvirongwa zviripo zvekutarisira chirwere cheshuga kana mamwe mishonga asingapi kutonga kwakakwana ega.

Mishonga iyi inogona kubatsira zvikuru vanhu vanoona kuwedzera kweshuga yeropa mushure mekudya. Sezvo sitagliptin inoshanda nemhinduro yako yemuviri yechisikigo ye insulin, inogona kubatsira kupfavisa kukwira kweglucose mushure mekudya pasina kukonzera zviitiko zvinotyisa zve shuga yeropa yakaderera.

Mune dzimwe nguva, sitagliptin inogona kunyorerwa sechikamu chekurapa kwakabatanidzwa pamwe chete nemetformin, sulfonylureas, kana insulin. Iyi nzira inobvumira timu yako yehutano kuti igadzire chirongwa chekurapa chakagadzirirwa zvaunoda uye chimiro chehutano.

Sitagliptin Inoshanda Sei?

Sitagliptin inoshanda nekudzivisa enzyme inonzi DPP-4 iyo inowanzo putsa mahomoni anobatsira mudumbu rako. Kana mahomoni aya akagara kwenguva refu, anogona kuita basa rakanaka rekutarisira shuga yako yeropa.

Zvinotevera ndizvo zvinoitika paunotora sitagliptin: mushure mekudya, matumbu ako anoburitsa mahomoni anonzi incretins ayo anoratidza pancreas yako kuti iite insulin uye kuudza chiropa chako kuti chimise kugadzira glucose yakawanda. Kazhinji, iyo DPP-4 enzyme inokurumidza kuputsa mahomoni aya anobatsira, asi sitagliptin inomisa kuparadzwa uku.

Maitiro aya anoita kuti sitagliptin ive iyo vanachiremba vanoti mishonga

Sitagliptin inofungidzirwa semushonga wechirwere cheshuga une simba repakati nepakati pane kuva nesimba guru. Kunyange zvazvo zvingasadzika shuga yeropa zvakanyanya se insulin kana mamwe mishonga, chiito chayo chinyoro uye njodzi shoma yemigumisiro yacho inoita kuti ive chishandiso chinokosha kune vanhu vazhinji vane chirwere cheshuga che rudzi rwechipiri.

Ndingatora Sei Sitagliptin?

Sitagliptin inowanzo torwa kamwe chete pazuva, uye unogona kuitora uine kana usina chikafu. Vanhu vazhinji vanoona zviri nyore kuitora panguva imwe chete zuva rega rega kubatsira kuyeuka uye kuchengetedza mazinga eropa emushonga.

Haufaniri kunetseka nezve nguva yekutora sitagliptin nezvokudya sezvo chikafu chisinganyanyi kukanganisa kuti muviri wako unochitora sei. Vamwe vanhu vanosarudza kuitora nekudya kwemangwanani kuti vagadzire tsika, nepo vamwe vachiwana zviri nyore kuitora nekudya kwemanheru kana panguva yekurara.

Gara uchimedza piritsi rose nemvura. Usapwanya, kutsenga, kana kuputsa piritsi, sezvo izvi zvinogona kukanganisa kuti mushonga unoburitswa sei mumuviri wako. Kana uine dambudziko rekumedza mapiritsi, taura nemufesi wako wemishonga kana chiremba nezve nzira dzinogona kubatsira.

Dosi inowanzo tangwa nayo i100 mg kamwe chete pazuva, kunyange chiremba wako angachinja izvi zvichienderana nebasa rematsvo ako nezvimwe zvinhu zvehutano. Kana uine matambudziko ematsvo, unogona kupiwa dosi yakaderera kuti uve nechokwadi chokuti mushonga unogadziriswa zvakachengeteka nemuviri wako.

Ndingatora Sitagliptin Kwenguva Yakareba Sei?

Sitagliptin inowanzoita mushonga wenguva refu waunozoenderera mberi uchitora chero bedzi uchibatsira kudzora chirwere chako cheshuga zvinobudirira. Chirwere cheshuga che rudzi rwechipiri chirwere chisingaperi chinoda kurapwa nguva dzose, saka vanhu vazhinji vanoramba vachitora mishonga yavo yechirwere cheshuga kwenguva isingagumi.

Chiremba wako achatarisa kuti sitagliptin iri kushanda zvakanaka sei kwauri kuburikidza nemiedzo yeropa yenguva dzose, kunyanya mazinga ako eA1C, ayo anoratidza avhareji yeshuga yeropa rako mumwedzi miviri mitatu yapfuura. Miedzo iyi inowanzoitika mwedzi mitatu mitanhatu yega yega uye inobatsira kuona kana chirongwa chako chekurapa chazvino chiri kuzadzisa zvinangwa zvako.

Vamwe vanhu vangangoda kuwedzera mamwe mishonga kuchirongwa chavo nekufamba kwenguva, sezvo chirwere cheshuga chinogona kufambira mberi uye chichida rubatsiro rwakawedzerwa. Izvi hazvirevi kuti sitagliptin yakamira kushanda, asi kuti zvaunoda mumuviri wako zvachinja, izvo zvakajairika zvachose nechinhu ichi.

Usambomira kutora sitagliptin kamwe kamwe usati wataura nemupi wako wehutano kutanga. Kunyangwe iwe uchinzwa zvakanaka uye shuga yako yeropa ichiita seyakamira, kumisa mishonga yeshuga kamwe kamwe kunogona kukonzera kuti mazinga eshuga yeropa ako akwire nekukurumidza, zvichikonzera matambudziko akakomba.

Ndezvipi Zvipingamupinyi zveSitagliptin?

Vanhu vazhinji vanotsungirira sitagliptin zvakanaka, asi semishonga yese, inogona kukonzera matambudziko kune vamwe vanhu. Mashoko akanaka ndeokuti matambudziko akakomba haawanzoitiki, uye vanhu vazhinji havana matambudziko zvachose.

Ngatitange nemigumisiro yakajairika yaungasangana nayo, iyo inowanzoita vanhu vashoma vanotora mushonga:

• Zvirwere zvepamusoro zvekufema zvakadai sema colds kana zvirwere zve sinus
• Musoro unowanzoita munyoro uye wenguva pfupi
• Mhino yakavharika kana inoyerera
• Huro inorwadza
• Dumbu rakashata kana kusvotwa

Izvi zvinowanzoitika zvinowanzoita munyoro uye zvinowanzoita nani sezvo muviri wako uchigadzirisa kumishonga. Vanhu vazhinji vanowana kuti vanogona kuramba vachitora sitagliptin vasina kusagadzikana kukuru.

Kune zvakare mamwe matambudziko asingawanzoitiki asi akakomba anoda kutariswa kwekurapa nekukurumidza. Kunyange izvi zvichiitika kazhinji, zvakakosha kuziva zvekutarisa:

• Kurwadziwa kwakanyanya mudumbu kungaratidza pancreatitis (kuzvimba kwepancreas)
• Kusvotwa uye kurutsa zvisingapere
• Maitiro akakomba ekuita allergic anosanganisira rash, kutsvuka, kuzvimba, kana kuoma kufema
• Kurwadziwa mumajoini kwakanyanya kana kusingavandudziki
• Maitiro eganda asingawanzoitika kana kuita mablister

Kana ukaona chero zviratidzo izvi zvakakomba, taura nachiremba wako nekukasika kana kutsvaga rubatsiro rwekurapa rwekukurumidza.

Kazhinji, sitagliptin yakabatana nemamiriro anonzi bullous pemphigoid, iyo inokonzera mablister paganda. Mamiriro eganda akakomba aya anoda kutarisirwa kwekurapa nekukasika asi anokanganisa vanhu vashoma vanopfuura 1 kubva pa10,000 vanotora mushonga.

Ndiani Asingafaniri Kutora Sitagliptin?

Sitagliptin haina kukodzera munhu wese ane chirwere cheshuga. Vanhu vane chirwere cheshuga chetype 1 kana diabetic ketoacidosis havafaniri kutora mushonga uyu, sezvo wakagadzirirwa zvakananga chirwere cheshuga chetype 2 uye haizopa rutsigiro rwe insulin runodiwa kune mamiriro aya.

Unofanira kuudza chiremba wako nezvezvinhu zvese zvaunogona kuita allergic usati watanga sitagliptin. Kana wakambove ne allergic reaction ku sitagliptin kana chero DPP-4 inhibitor mushonga munguva yakapfuura, mushonga uyu hauna kuchengeteka kwauri.

Vanhu vane mamwe mamiriro ehutano vanoda kufunga zvakakosha vasati vatora sitagliptin. Chiremba wako achada kuziva kana uine:

• Chirwere cheitsvo kana kushanda kweitsvo kwakaderera
• Nhoroondo ye pancreatitis (kuzvimba kwepancreas)
• Matambudziko emoyo kana kukundikana kwemoyo
• Gallstones kana chirwere chegallbladder
• Nhoroondo yekurwadziwa kwakanyanya mumajoini kana arthritis

Mamiriro aya haakudzivise otomatiki kutora sitagliptin, asi anogona kuda kugadzirisa dose kana kuongororwa pedyo kuti uve nechokwadi chekuchengeteka kwako.

Kana wakaita pamuviri, urikuronga kuita pamuviri, kana kuti uri kuyamwisa, taura izvi nachiremba wako. Kunyange zvazvo sitagliptin isina kuratidzwa kuti inokonzera kukuvadza panguva yekuzvitakura, chiremba wako anogona kukurudzira dzimwe nzira dzekutarisira chirwere cheshuga panguva ino.

Mazita eSitagliptin Brand

Sitagliptin inowanikwa pasi pezita rekuti Januvia, iro ndiro fomu rinonyanya kunyorerwa remushonga uyu. Januvia ine sitagliptin sechikamu chayo chinoshanda uye inogadzirwa neMerck & Co.

Unogonawo kusangana nemishonga yakasanganiswa inosanganisira sitagliptin pamwe chete nemimwe mishonga yeshuga. Janumet inobatanidza sitagliptin nemetformin, nepo Janumet XR iri vhezheni yakawedzerwa-yekuburitsa yemusanganiswa uyu inotorwa kazhinji.

Mavhezheni eGeneric e sitagliptin ave kuwanikwa munyika dzakawanda, izvo zvinogona kuita kuti mushonga uyu utengeke. Aya mavhezheni e generic ane chinhu chimwe chete chinoshanda uye anoshanda zvakanyanya sezvakaita vhezheni yezita remhando.

Kunyange iwe ukagamuchira zita remhando kana generic sitagliptin kazhinji zvinoenderana nekavharo yako yeinishuwarenzi uye zvaunofarira zvemishonga. Mavhezheni ese ari maviri anoshanda zvakaenzana, saka unogona kunzwa wakasununguka nezve chero fomu rinonyorerwa nachiremba wako.

Zvimwe Zvinhu Zvitsva zveSitagliptin

Kana sitagliptin isiri iyo yakakunakira, mamwe mishonga yeshuga anogona kupa mabhenefiti akafanana. Zvimwe zvinodzivirira DPP-4 zvakaita se linagliptin (Tradjenta), saxagliptin (Onglyza), uye alogliptin (Nesina) zvinoshanda nenzira imwecheteyo se sitagliptin.

GLP-1 receptor agonists inomiririra imwe kirasi yemishonga yeshuga inoshanda nemasisitimu ako emuviri ehomoni. Izvi zvinosanganisira mishonga yakaita se liraglutide (Victoza), semaglutide (Ozempic), uye dulaglutide (Trulicity), kunyangwe izvi zvinowanzo kupihwa semajekiseni panzvimbo yemishonga yemuromo.

Kune vanhu vanoda mishonga inotorwa nemuromo, SGLT-2 inhibitors senge empagliflozin (Jardiance) uye canagliflozin (Invokana) inopa imwe nzira nekubatsira itsvo dzako kubvisa glucose yakawandisa kuburikidza neweti. Mishonga iyi inogonawo kupa mwoyo uye itsvo dzokudzivirira.

Mishonga yechinyakare ye diabetes senge metformin, sulfonylureas, uye insulin inoramba iri nzira dzakakosha dzekurapa zvichienderana nezvido zvako uye hutano hwako. Murapi wako wehutano anogona kubatsira kuona kuti ndeipi mushonga kana musanganiswa wemishonga uchashanda zvakanyanya kune mamiriro ako.

Sitagliptin iri nani kupfuura Metformin here?

Sitagliptin uye metformin zvinoshanda zvakasiyana uye zvinowanzo shandiswa pamwechete pane senzira dzakasiyana. Metformin inowanzoita yekutanga-mutsara kurapwa kwechirwere cheshuga che2 nekuti yakashandiswa zvakachengeteka kwemakumi emakore uye ine zvakaratidza zvakanakira hutano hwemoyo uye manejimendi ehuremu.

Metformin inoshanda zvakanyanya nekuderedza huwandu hwe glucose inogadzirwa nechiropa chako uye nekuvandudza kunzwisiswa kwemuviri wako kune insulin. Inowanzoita inoshanda zvakanyanya pakuderedza mazinga eshuga yeropa pane sitagliptin yega, ndosaka ichiwanzova hwaro hwekurapa chirwere cheshuga.

Zvisinei, sitagliptin ine zvimwe zvakanakira pamusoro pe metformin kune vamwe vanhu. Zviri kashoma kukonzera dumbu kugumbuka kana matambudziko ekugaya, izvo zvinogona kuve nyaya dzakakosha ne metformin. Sitagliptin zvakare haisi kazhinji kukonzera kuwedzera uremu uye ine njodzi yakaderera yekukonzera zviitiko zvepasi shuga yeropa.

Vanhu vazhinji vanopedzisira vachitora mishonga yese iri miviri pamwechete nekuti vanozadzisana zvakanaka. Musanganiswa we metformin uye sitagliptin (inowanikwa seJanumet) inogona kupa nani kudzora shuga yeropa kupfuura chero mushonga wega asi uchiita chimiro chine hunyoro hwekuita.

Mibvunzo Inowanzo Bvunzwa Nezve Sitagliptin

Sitagliptin Yakachengeteka Here Kune Chirwere Chemoyo?

Sitagliptin yakadzidzwa zvakanyanya muvanhu vane chirwere chemoyo uye inowanzofungidzirwa kuti yakachengeteka kuboka iri. Miedzo mikuru yekiriniki yakaratidza kuti sitagliptin haina kuwedzera njodzi yekurwiswa nemoyo, sitiroko, kana kufa kwemoyo zvichienzaniswa ne placebo.

Muchokwadi, kutarisira chirwere chako cheshuga zvakanaka nemishonga yakaita se sitagliptin kunogona kubatsira kuchengetedza moyo wako munguva refu. Mazinga epamusoro eshuga yeropa nekufamba kwenguva anogona kukuvadza tsinga dzeropa uye kuwedzera njodzi yemoyo, saka kuchengeta chirwere chako cheshuga pasi pekutonga ndechimwe chezvinhu zvakanakisisa zvaunogona kuita kumoyo wako.

Kana uine chirwere chemoyo, chiremba wako achafunga nezve hutano hwako hwese paanonyora mishonga yechirwere cheshuga. Vanogona kusarudza sitagliptin nekuda kwemigumisiro yayo isina kwainotsinhira pamoyo, kana vanogona kusarudza mamwe mishonga yechirwere cheshuga yakaratidzwa kuti inopa dziviriro yakawedzerwa yemoyo.

Ndoita Sei Kana Ndikashandisa Sitagliptin Yakawanda Nenzira Isina Kufanira?

Kana ukatora sitagliptin yakawanda nenzira isina kufanira kupfuura yakarairwa, usavhunduka. Kusiyana nemimwe mishonga yechirwere cheshuga, sitagliptin haina kukonzera mazinga eshuga yeropa akaderera anotyisa kunyangwe ukatora yakawanda, nekuti inoshanda chete kana shuga yako yeropa yakakwira.

Zvisinei, iwe unofanirwa kuchine kubata chiremba wako kana wezve mishonga kuti utaure nezve overdose uye uwane gwara rekuti utaure sei. Vanogona kukurudzira kutarisa shuga yako yeropa kakawanda kwemaawa makumi maviri nemana anotevera kana kutarisa chero zviratidzo zvisingawanzoitiki.

Kana iwe wakatora sitagliptin yakawanda kwazvo kana uri kusangana nezviratidzo zvinonetesa zvakaita senausea yakanyanya, kurutsa, kana kurwadziwa mudumbu, tsvaga rubatsiro rwekurapa nekukasira. Kunyange zvazvo migumisiro yakakomba ye overdose isingawanzoitiki, zviri nani nguva dzose kukanganisa pane rumwe rutivi rwekuchenjerera.

Kuti mudzivise kuwedzera mishonga netsaona mune ramangwana, funga kushandisa chirongwa chemishonga kana kumisa zviyeuchidzo zvefoni kuti zvikubatsire kuchengeta zvaunotora mishonga yako. Izvi zvinobatsira zvikuru kana uchitora mishonga yakawanda zuva rese.

Ndoita Sei Kana Ndakanganwa Kudya Mishonga yeSitagliptin?

Kana ukakanganwa kudya mishonga ye sitagliptin, idye nekukasira paunorangarira, kunze kwekunge yava nguva yekutora imwe dose. Muchiitiko ichocho, siya dose yakakanganwika uye uenderere mberi nechirongwa chako chekudya mishonga.

Usambofa wakatora madosi maviri e sitagliptin panguva imwe chete kuti ugadzirise dose yakakanganwika. Izvi hazvizobatsiri zvakanyanya uye zvinogona kuwedzera njodzi yako yekuwana matambudziko. Kudzora shuga yeropa rako hakuzokanganiswi zvakanyanya nekukanganwa dose imwe chete.

Kana uchikanganwa kazhinji kutora mishonga yako, taura nachiremba wako nezve nzira dzekukubatsira kurangarira. Vanogona kukupa zano rekuitora panguva yakasiyana yezuva inokodzera zviri nani nehurongwa hwako, kana kukupa zano rematurusi akadai seapps dze smartphone kana zvirongwa zvemapiritsi.

Kukanganwa madosi dzimwe nguva hakuna njodzi, asi kugara uchikanganwa kutora mishonga yako yechirwere cheshuga kunogona kukonzera kusadzora shuga yeropa nekufamba kwenguva. Kutevedzera mishonga zvakanaka kwakakosha kudzivirira matambudziko echirwere cheshuga uye kuchengetedza hutano hwako hwese.

Ndingamira Rini Kutora Sitagliptin?

Unofanira kungomira kutora sitagliptin pasi pekutungamirirwa nachiremba wako. Kunyangwe mazinga eshuga yeropa rako akavandudzika zvakanyanya, izvi zvinowanzoitika nekuti mishonga iri kushanda, kwete nekuti hauchadi.

Vamwe vanhu vanoshamisika kana vachigona kumisa mishonga yavo yechirwere cheshuga mushure mekuonda kana kuita shanduko huru muhupenyu. Kunyangwe izvi zvivandudzo zvakanaka uye zvinogona kuderedza zvaunoda mishonga, sarudzo yekumisa kana kuderedza mishonga yechirwere cheshuga inofanira kugara ichiitwa nekutarisa kwechiremba.

Chiremba wako achafunga zvinhu zvakawanda paanenge achisarudza kana iwe uchikwanisa kuderedza zvakachengeteka kana kumisa sitagliptin, kusanganisira mazinga ako eA1C achangoburwa, hutano hwako hwese, mamwe mishonga yaunotora, uye kuti wava nenguva yakareba sei uine chirwere cheshuga. Vanogona kukurudzira kuderedzwa zvishoma nezvishoma panzvimbo pokumisa zvachose.

Kana iwe uchifarira kuderedza mishonga yako yechirwere cheshuga, tarisa pakuchengetedza shanduko dzehupenyu hune hutano dzakavandudza kutonga kweshuga yeropa rako. Ramba uchishanda nechikwata chako chehutano kuti uongorore kufambira mberi kwako uye uite shanduko dzemishonga zvakachengeteka kana zvakakodzera.

Ndingatora Sitagliptin nemimwe mishonga here?

Sitagliptin inowanzobatana zvakanaka nemimwe mishonga yakawanda, asi zvakakosha kuti uudze mupi wako wehutano nezvezvose zvauri kutora, kusanganisira mishonga inopiwa nachiremba, mishonga inotengeswa pasina mushonga, mavitamini, uye zvinowedzera zvemishonga yemakwenzi.

Mamwe mishonga anogona kukanganisa mashandiro anoita sitagliptin kana kuwedzera njodzi yako yemigumisiro. Semuenzaniso, mamwe maantibiotics nemishonga yekurwisa fungal anogona kuchinja maitiro anoita muviri wako sitagliptin, kunyangwe hukama uhu hunowanzo manejwa nekugadzirisa dosi.

Kana iwe uchitora mamwe mishonga yechirwere cheshuga pamwe chete ne sitagliptin, chiremba wako achakutarisa zvakanyanya kuti uone zviitiko zvepasi shuga yeropa. Nepo sitagliptin yega ichiwanzo kukonzera hypoglycemia, kusanganiswa nemamwe madhiragi echirwere cheshuga kunogona kuwedzera njodzi iyi.

Gara uchizivisa chero vapi vehutano vatsva kuti uri kutora sitagliptin, kusanganisira vanachiremba vemazino, nyanzvi, uye vanachiremba vekamuri yekukurumidzira. Izvi zvinobatsira kuona kuti vanogona kunyora mamwe mishonga zvakachengeteka uye kudzivirira hukama hunogona kukanganisa manejimendi ako echirwere cheshuga.