Chii chinonzi Sodium Phenylacetate uye Benzoate: Zvavanoshandiswa, Dosage, Migumisiro Yemuviri uye Zvimwe

Sodium phenylacetate uye benzoate mushonga unoponesa hupenyu unoshandiswa kurapa mazinga ane njodzi eammonia muropa rako. Musanganiswa uyu unoshanda semushonga wemukana kana muviri wako usingakwanise kubvisa ammonia zvakanaka, chigadzirwa chemarara chine chepfu chinogona kukuvadza uropi hwako nemamwe nhengo kana ikavaka zvakanyanya.

Chii chinonzi Sodium Phenylacetate uye Benzoate?

Sodium phenylacetate uye benzoate mushonga unopiwa nachiremba unouya semvura yakajeka inopiwa mutsinga yako. Iyo ine zvinoshanda zviviri zvinoshanda pamwechete kubatsira muviri wako kubvisa ammonia yakawandisa kana hurongwa hwako hwekubvisa marara husiri kushanda nemazvo.

Mushonga uyu unowanzo shandiswa munzvimbo dzekuchipatara pasi pekutariswa kwechiremba. Chikwata chako chehutano chichakutarisa zvakanyanya paunogamuchira mushonga uyu kuti uve nechokwadi chekuti uri kushanda nemazvo uye zvakachengeteka.

Sodium Phenylacetate uye Benzoate inoshandiswa nei?

Mushonga uyu unorapa hyperammonemia, zvinoreva kuva neammonia yakawandisa muropa rako. Inonyanya kushandiswa kune vanhu vane urea cycle disorders, mamiriro emagenetic asingawanzoitiki apo muviri wako usingakwanise kuparadza mapuroteni zvakanaka.

Chiremba wako angakupa mushonga uyu kana uine mamiriro akaita seornithine transcarbamylase deficiency, carbamoyl phosphate synthetase deficiency, kana argininosuccinate synthetase deficiency. Mamiriro aya anogona kukonzera ammonia kuvaka kusvika pamazinga ane njodzi, zvichikonzera kukuvadzwa kwehuropi kana coma kana isina kurapwa nekukurumidza.

Dzimwe nguva vanachiremba vanoshandisawo mushonga uyu kune zvimwe zvikonzero zvemazinga epamusoro eammonia, senge chirwere chakakomba chechiropa kana mamwe matambudziko emetabolic. Chinhu chakakosha ndechekuti mazinga ako eammonia anofanira kudzika nekukurumidza kudzivirira uropi hwako nemamwe nhengo dzakakosha.

Sodium Phenylacetate uye Benzoate inoshanda sei?

Mishonga iyi inoshanda nekupa muviri wako nzira imwe yekubvisa ammonia muropa rako. Fungidzira sekugadzira nzira yekumhanya kana mugwagwa mukuru wakavharika.

Kazhinji, chiropa chako chinoshandura ammonia kuita urea, yaunobva wabvisa nemumugumo. Kana maitiro aya asingashande zvakanaka, sodium phenylacetate uye benzoate zvinopinda kuti zvikubatsire. Zvinobatana neammonia nemamwe marara e nitrogen, zvichivashandura kuita zvinhu zviri nyore kuti itsvo dzako dzibvise.

Iyi inofungidzirwa semushonga wakasimba, unokurumidza kushanda nekuti mazinga epamusoro e ammonia idambudziko rekurapa. Kurapa kunowanzo kutanga kushanda mukati meawa, asi iwe uchada kuongororwa zvakanyatsojeka kuti uve nechokwadi chekuti mazinga ako e ammonia ari kudonha zvakachengeteka.

Ndingatora Sei Sodium Phenylacetate uye Benzoate?

Uchagamuchira mushonga uyu nemutsara we IV mutsinga yako, nguva dzose uri muchipatara. Chikwata chako chekurapa chichaverenga chiyero chaicho zvichienderana nehuremu hwako uye kuoma kwemamiriro ako.

Mishonga inowanzo kupihwa sekuiswa kunoenderera mberi kwemaawa makumi maviri nemana, yakavhenganiswa nemhinduro yeshuga inonzi dextrose. Chikwata chako chehutano chichatarisa mazinga ako eropa nguva dzose kuti uchinje chiyero sezvinodiwa.

Haufanire kunetseka nezve zvirambidzo zvekudya panguva yekurapa, asi chiremba wako anogona kukurudzira kudya kwakaderera-mapuroteni kuti ubatsire kuderedza kugadzirwa kwe ammonia. Vamwe varwere vanogashirawo mamwe mishonga pamwe chete nekurapa uku kuti vawedzere kushanda.

Ndingatora Kwenguva Yakareba Sei Sodium Phenylacetate uye Benzoate?

Kureba kwekurapa kunoenderana nekukurumidza kwemazinga ako e ammonia anodzokera kumazinga akachengeteka. Vanhu vazhinji vanogashira mushonga uyu kwemaawa makumi maviri nemana kusvika makumi mana nemasere, asi vamwe vangada kurapwa kwenguva refu.

Chikwata chako chekurapa chichatarisa mazinga ako eropa e ammonia maawa mashoma ega ega kuti uone kuti kurapa kuri kushanda sei. Kana mazinga ako agadziriswa uye achitanga kudonha nguva dzose, chiremba wako achatanga kuronga kuchinjira kune mamwe marapirwo.

Kune vanhu vane zvirwere zveurea cycle zvisingaperi, izvi zvinogona kureva kuchinja kumishonga yemumuromo inobatsira kudzora mazinga eammonia kwenguva refu. Chiremba wako achashanda newe kuti vagadzire chirongwa chakazara chekurapa chekuchengetedza kwenguva refu.

Ndezvipi Zvakaipa zveSodium Phenylacetate uye Benzoate?

Semishonga yese, sodium phenylacetate uye benzoate inogona kukonzera matambudziko, kunyangwe kwete munhu wese achawana. Chikwata chako chekurapa chichakutarisa zvakanyanya kune chero maitiro panguva yekurapa.

Matambudziko akajairika aunogona kusangana nawo anosanganisira kusvotwa, kurutsa, uye kurwadziwa nemusoro. Vamwe vanhu vanoonawo shanduko mukunzwisisa kwavo kuravira kana kunhuhwirira, kunyanya kuravira kwesimbi mumuromo mavo.

Heano matambudziko anowanzoitika, akarongwa kubva kune akajairika kusvika kune asingawanzoitiki:

• Kusvotwa uye kurutsa
• Kurwadziwa nemusoro
• Dizziness
• Kushanduka mukuravira kana kunhuhwirira
• Maitiro ekudzivirira jekiseni senge kutsvuka kana kuzvimba
• Kuneta kana kusimba
• Kurwadziwa mudumbu kana kusagadzikana

Matambudziko aya anowanzoitika anowanzo manejwa uye anowanzoita nani muviri wako uchigadzirisa kumishonga. Chikwata chako chehutano chinogona kupa kurapwa kubatsira nekusvotwa kana zvimwe zviratidzo zvisina kunaka.

Matambudziko akakomba anogona kuitika asi haawanzoitiki. Izvi zvinoda kutariswa kwekurapa nekukurumidza uye zvinosanganisira maitiro akakomba ekurwara, kurova kwemoyo kusingaite, kana shanduko dzakakosha mumamiriro ako epfungwa.

Matambudziko asingawanzoitiki asi akakomba anosanganisira:

• Maitiro akakomba ekurwara nekufema kwakaoma kana kuzvimba
• Kurova kwemoyo kusingaite kana kurwadziwa muchipfuva
• Kuvhiringidzika kwakanyanya kana shanduko mukuziva
• Kubuda ropa kusingaite kana kupwanya
• Matambudziko akakomba echiropa
• Kusagadzikana kweElectrolyte kunokanganisa basa remoyo

Chikwata chako chekurapa chakadzidziswa kuziva nekukurumidza nekurapa matambudziko aya asingawanzoitiki. Nzvimbo yechipatara inovimbisa kuti unogamuchira kutarisirwa nekukurumidza kana chero mhedzisiro yakakomba ikaitika.

Ndiani Asingafaniri Kutora Sodium Phenylacetate uye Benzoate?

Nepo mushonga uyu uchinyanya kuchengeteka kune vanhu vazhinji vanouda, pane dzimwe nguva dzausingakodzere. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati watanga kurapwa.

Unofanira kuudza chikwata chako chehutano kana uine chirwere chakakomba cheitsvo, sezvo itsvo dzako dzinoda kukwanisa kubvisa marara anogadzirwa nemushonga uyu. Vanhu vane mamwe mamiriro emoyo vanogonawo kuda kuongororwa zvakakosha panguva yekurapwa.

Chiremba wako achadawo kuziva nezve chero allergies dzaunadzo, kunyanya kumishonga kana zvinochengetedza. Vakadzi vane pamuviri kana vanoyamwisa vanoda kutariswa zvakakosha, kunyangwe mushonga uyu uchiri kushandiswa kana mabhenefiti achipfuura njodzi.

Vanhu vane chirwere chakakomba chechiropa vanogona kuda kugadzirisa mushonga, sezvo mushonga uyu dzimwe nguva unogona kukanganisa basa rechiropa. Chikwata chako chekurapa chichanyatsoongorora chiropa chako kana uine matambudziko echiropa aripo.

Sodium Phenylacetate uye Benzoate Mazita eBrand

Zita rinowanzozivikanwa remushonga uyu ndiAmmonul. Iyi ndiyo vhezheni iyo zvipatara zvakawanda zvinochengeta uye zvinoshandisa kurapa mazinga epamusoro eammonia.

Zvimwe zvivakwa zvinogona kushandisa generic versions kana akasiyana mafomu, asi ese ane zvakafanana zvinoshanda. Chikwata chako chekurapa chichavimbisa kuti unogamuchira vhezheni yakakodzera yezvaunoda.

Sodium Phenylacetate uye Benzoate Zvimwe Zvinhu

Kune mamwe mishonga anogona kubatsira kubata mazinga epamusoro eammonia, zvichienderana nemamiriro ako chaiwo. L-arginine dzimwe nguva inoshandiswa padivi kana panzvimbo pe sodium phenylacetate uye benzoate kune mamwe marudzi eurea cycle disorders.

Pakuongorora kwenguva refu, mishonga inotorwa nemuromo yakaita se sodium phenylbutyrate kana glycerol phenylbutyrate inogona kuva sarudzo. Izvi zvinoshanda zvakafanana asi zvinogona kutorwa nemuromo kumba panzvimbo pokuda kurapwa muchipatara.

Mune dzimwe nguva, shanduko dzekudya uye zvinowedzerwa zvakadai se L-carnitine kana N-acetylcysteine ​​zvinogona kubatsira kutsigira maitiro emuviri wako ekubvisa ammonia. Chiremba wako achashanda newe kuti awane musanganiswa wakanakisisa wekurapa mamiriro ako.

Ko Sodium Phenylacetate uye Benzoate Zviri Nani Kupfuura L-Arginine?

Mishonga yose iri miviri inoshanda mabasa akakosha mukurapa mazinga epamusoro e ammonia, asi anoshanda nenzira dzakasiyana. Sodium phenylacetate uye benzoate inowanzo shandiswa kune zviitiko zvakanyanya kana mazinga e ammonia ari panjodzi.

L-arginine inoshanda nekutsigira muviri wako we urea cycle, ichiibatsira kushanda zvakanyanya. Inowanzo shandiswa kune mhando dzakasiyana dze urea cycle disorders, kunyanya idzo dzinokanganisa arginine metabolism.

Chiremba wako angashandisa mishonga yose iri miviri pamwe chete, sezvo inogona kuzadzisa mhedzisiro yavo. Sarudzo inoenderana nemamiriro ako chaiwo, kuti mazinga ako e ammonia akakomba sei, uye kuti muviri wako unopindura sei kurapwa.

Mibvunzo Inowanzo Bvunzwa Nezve Sodium Phenylacetate uye Benzoate

Mubvunzo 1. Ko Sodium Phenylacetate uye Benzoate Zvakachengeteka Kuvana?

Hongu, mushonga uyu unowanzo shandiswa muvana uye unowanzo chengetedza hupenyu kune varwere vevana vane urea cycle disorders. Vana vanowanzo shivirira mushonga zvakanaka, kunyangwe vachida kunyatsoongororwa sezvakaita vanhu vakuru.

Dosing yevana inoverengwa zvichibva pahuremu hwemuviri wavo uye nzvimbo yepamusoro. Nyanzvi dzevana dzine ruzivo mukugadzirisa kurapwa uku uye kutarisa chero mhedzisiro inogona kuwanzana muvarwere vadiki.

Mubvunzo 2. Ndoitei kana ndikawana mhedzisiro yakakomba?

Sezvo muchagamuchira mushonga uyu muchipatara, chikwata chenyu chekurapa chichakutarisa zvakanyanya kuti chione kana paine matambudziko. Kana ukaona zviratidzo zvakakomba zvakaita sekufema zvakaoma, kurwadziwa muchipfuva, kana shanduko huru mukuita kwako, zivisa mukoti wako kana chiremba wako nekukasira.

Vashandi vechipatara vakadzidziswa kuziva nekukurumidza nekurapa mhedzisiro yakakomba. Usazeze kutaura nezvezvinhu zvinokunetsa, kunyangwe zvichioneka sezviri zvidiki.

Q3. Ndingatora Mamwe Mishonga Ndichiri Kuwana Kurapa Uku Here?

Chikwata chako chekurapa chichanyatsoongorora mishonga yako yese usati watanga kurapwa. Dzimwe mishonga inogona kuita pamwe chete nesodium phenylacetate uye benzoate, saka vanachiremba vako vangada kugadzirisa zviyero kana kumisa kwenguva pfupi mishonga yakati.

Nguva dzose udza chikwata chako chehutano nezvemishonga yese, zvinowedzera, uye zvigadzirwa zvemiti zvauri kutora. Izvi zvinosanganisira mishonga inotengeswa pasina mushonga uye chero kurapwa kwawakagamuchira nguva pfupi yadarika.

Q4. Ndichaziva Sei Kana Kurapa Kuchishanda?

Chikwata chako chekurapa chichatarisa mazinga ako eropa ammonia nguva dzose panguva yekurapa, kazhinji maawa mashoma ega ega. Unofanirwa kuona mazinga aya achiderera mukati mezuva rekutanga rekurapa kana mushonga uchishanda nemazvo.

Unogonawo kuona kuvandudzwa muzviratidzo zvakaita sekukanganiswa, kusvotwa, kana kuneta sezvo mazinga ako eammonia achidzika. Chikwata chako chehutano chichakuchengeta uchiziva nezve kufambira mberi kwako uye kutsanangura zvinoreva nhamba.

Q5. Chii Chinoitika Mushure mekuita Kwangu Ammonia Levels Kuti Dzidzokere Kune Zvakajairika?

Kana mazinga ako eammonia agadziriswa, chikwata chako chekurapa chichashanda newe kugadzira chirongwa chekuchengetedza kwenguva refu. Izvi zvinogona kusanganisira mishonga yemuromo, shanduko dzekudya, kana kuongorora nguva dzose kudzivirira zviitiko zveramangwana.

Kana uine chirwere che urea cycle, ungangoda kurapwa nguva dzose uye kuteverwa nevanyanzvi vanonzwisisa zvirwere izvi. Chiremba wako achabatsira kuronga kutarisirwa kwako uye kuona kuti une rutsigiro rwaunoda mberi.