Cholangitis Sclerosis Primary

Maraqa muruqyadu waxay qaadaan maraqa beerkaaga ilaa mindhicirkaaga yar. Marka maraqa muruqyadu dhaawacmaan, maraqu wuxuu ku soo noqon karaa beerka, taasoo keenta dhaawaca unugyada beerka. Dhaawacan wuxuu keeni karaa fashilka beerka.

Cholangitis-ka aasaasiga ah ee sclerosing (skluh-ROHS-ing) waa cudur ku dhaca maraqa muruqyada. Maraqa muruqyadu waxay qaadaan dareeraha dheef-shiidka ee maraqa beerkaaga ilaa mindhicirkaaga yar. Cholangitis-ka aasaasiga ah ee sclerosing, bararku wuxuu keenaa nabarrada gudaha maraqa muruqyada. Nabarradan waxay ka dhigaan muruqyada adag oo cidhiidhi ah waxayna si tartiib tartiib ah u keenaan dhaawac beer oo daran. Dadka intooda badan ee qaba cholangitis-ka aasaasiga ah ee sclerosing waxay kaloo qabaan cudurrada mindhicirka bararka, sida colitis ulcerative ama cudurka Crohn.

Dadka intooda badan ee qaba cholangitis-ka aasaasiga ah ee sclerosing, cudurku wuxuu si tartiib ah u socdaa. Ugu dambeyntii wuxuu keeni karaa fashilka beerka, infekshinka soo noqnoqda, iyo burooyinka maraqa muruqyada ama beerka. Beerta beerka waa daawo keliya oo la yaqaan oo loogu talagalay cholangitis-ka aasaasiga ah ee sclerosing ee horumarsan, laakiin cudurku wuxuu ku soo noqon karaa beerka la bedelay ee tiro yar oo bukaanno ah.

Daryeelka cholangitis-ka aasaasiga ah ee sclerosing wuxuu diiradda saarayaa kormeerka shaqada beerka, maareynta astaamaha iyo, marka ay suurtogal tahay, sameynta habraacyada si ku meel gaar ah u fura maraqa muruqyada oo xiran.

Primary sclerosing cholangitis waxaa inta badan la ogaadaa kahor inta aanu soo bixin calaamadaha marka baaritaanka dhiiga ee caadiga ah ama sawirka x-ray ee loo qaaday xaalad aan la xiriirin ay muujiyaan cillad ku dhacda beerka. Calaamadaha iyo astaamaha hore waxaa ka mid ah: Daal Xanuun Indho iyo maqaar jaale ah (jaundice) Xanuun calool Dad badan oo la ogaaday primary sclerosing cholangitis kahor inta aanay la kulmin calaamadaha waxay sii wadaan inay dareemaan caafimaad wanaagsan muddo dhowr sano ah. Laakiin ma jiraan hab lagu kalsoonaan karo oo lagu saadaalin karo sida dhakhsaha ama gaabnida cudurka uu u horumarayo qof kasta. Calaamadaha iyo astaamaha laga yaabo inay soo baxaan marka cudurka uu horumaro waxaa ka mid ah: Qandho Harraad Dhidid habeenkii Beer balaaran Beer balaaran Miisaan lumis Samee ballan la soco dhakhtarkaaga haddii aad qabto xanuun daran oo aan la garanayn oo ku badan jirkaaga - xanuun sii socda iyadoon loo eegin inta aad xoqdo. Sidoo kale booqo dhakhtarkaaga haddii aad dareento daal aad u daran wakhti kasta, wax kasta oo aad sameyso. Waxaa aad muhiim u ah inaad u sheegto dhakhtarkaaga daalka iyo xanuunka aan la garanayn haddii aad qabto ulcerative colitis ama Crohn's disease, labadaba waa noocyada cudurka mindhicirka bararka. Dadka intooda badan ee qaba primary sclerosing cholangitis waxay kaloo qabaan mid ka mid ah cudurradan.

Haddii aad qabto cuncun daran oo aan la garanayn sababta oo ku badan jirkaaga oo aan joogsanayn xataa haddii aad si aad ah isku xoqdo, la xiriir dhakhtarkaaga. Sidoo kale, booqo dhakhtarkaaga haddii aad dareento daal daran oo joogto ah, wax kasta oo aad sameyso. Waa muhiim in aad u sheegto dhakhtarkaaga daalka iyo cuncunka aan la garanayn sababta haddii aad qabto ulcerative colitis ama Crohn's disease, labadaba waa noocyo cudurrada bararka mindhicirka. Dadka intooda badan ee qaba primary sclerosing cholangitis waxay sidoo kale qabaan mid ka mid ah cudurradan.

Sababta keenta cudurka primary sclerosing cholangitis lama garanayo. Falcelinta nidaamka difaaca jirka ee ka dhalata infekshinka ama sunta ayaa laga yaabo inay keento cudurka dadka hidde ahaan u nugul.

Qayb aad u badan oo dadka qaba primary sclerosing cholangitis waxay kaloo qabaan cudurka mindhicirka bararka, erey guud oo ay ku jiraan ulcerative colitis iyo cudurka Crohn.

Primary sclerosing cholangitis iyo cudurka mindhicirka bararka ma soo baxaan isla waqtiga, inkastoo. Qaar ka mid ah xaaladaha, primary sclerosing cholangitis wuxuu joogaa sanado ka hor inta aan la helin cudurka mindhicirka bararka. Haddii la ogaado primary sclerosing cholangitis, waa muhiim in la raadiyo cudurka mindhicirka bararka maxaa yeelay waxaa jira halis weyn oo kansarka mindhicirka ah.

Inta yar, dadka la daaweynayo cudurka mindhicirka bararka waxay u muuqdaan inay sidoo kale qabaan primary sclerosing cholangitis. Iyo naadir, dadka qaba primary sclerosing cholangitis waxay ku dhacaan cudurka mindhicirka bararka ka dib marka la sameeyo tallaal beerka.

Waxyaabaha kordhin kara halista cudurka 'primary sclerosing cholangitis' waxaa ka mid ah:

• Da'da. Cudurka 'primary sclerosing cholangitis' wuxuu ku dhici karaa da' kasta, laakiin inta badan waxaa lagu ogaadaa da'da u dhaxaysa 30 iyo 40.
• Jins. Cudurka 'primary sclerosing cholangitis' wuxuu inta badan ku dhacaa ragga.
• Cudurka mindhicirka bararka leh. Qayb aad u badan dadka qaba cudurka 'primary sclerosing cholangitis' waxay kaloo qabaan cudurka mindhicirka bararka leh.
• Goobta Juqraafiyeed. Dadka leh dhaxalka Waqooyiga Yurub waxay halis sare ugu jiraan cudurka 'primary sclerosing cholangitis'.

Dhibaatooyinka ka dhalan kara sclerosing cholangitis-ka aasaasiga ah waxaa ka mid noqon kara:

• Xanuunka beerka iyo fashilka beerka. Bararka joogtada ah ee waddooyinka muruqyada ee ku yaal beerkaaga waxay keeni kartaa in unugyada beerku dhaawacmaan (cirrhosis), dhimashada unugyada beerka, iyo ugu dambeyntii, luminta shaqada beerka.
• Infections soo noqnoqda. Haddii nabarrada waddooyinka muruqyada ay yareeyaan ama joojiyaan socodka muruqyada ka soo baxa beerka, waxaad la kulmi kartaa infekshino badan oo ku dhaca waddooyinka muruqyada. Halista infekshanku aad ayay u sarreeyaa ka dib markaad qalliin ku samaysay si aad u ballaadhiso waddada muruqyada oo aad u nabaraysatay ama aad u saarto dhagax xannibay waddada muruqyada.
• Lafo khafiif ah. Dadka qaba sclerosing cholangitis-ka aasaasiga ah waxay la kulmi karaan lafo khafiif ah (osteoporosis). Dhakhtarkaagu wuxuu kugula talin karaa baaritaan cufnaanta lafaha si loo baaro osteoporosis dhowr sano kasta. Dheeraadyo kalsiyum iyo fiitamiin D ah ayaa laga yaabaa in la qoro si looga hortago luminta lafaha.
• ** Kansarka waddada muruqyada.** Haddii aad qabto sclerosing cholangitis-ka aasaasiga ah, waxaad halis sare ugu jirtaa inaad ku dhacdo kansarka waddooyinka muruqyada ama xubinta dhiig-baxa.
• Kansarka mindhicirka. Dadka qaba sclerosing cholangitis-ka aasaasiga ah oo la xiriira cudurka mindhicirka bararka waxay halis sare ugu jiraan kansarka mindhicirka. Haddii laguu ogaaday sclerosing cholangitis-ka aasaasiga ah, dhakhtarkaagu wuxuu kugula talin karaa baaritaanka cudurka mindhicirka bararka, xitaa haddii aadan lahayn calaamado ama astaamo, maadaama halista kansarka mindhicirka ay sare u kacdo haddii aad qabto labada cudur.

Cadaadiska xididdada beerka wuxuu keeni karaa in dareeraha beerka uu u daato calooshaada (ascites). Waxa kale oo uu ka leexin karaa dhiiga xididka beerka xididdada kale, taasoo keenta in xididdadaasi bararaan (varices). Varices waa xididdada daciifka ah waxayna u janjeeraan inay si fudud u dhiig baxaan, taasoo nolosha halis gelin karta.

Endoscopic retrograde cholangiopancreatography (ERCP) waa farsamo isticmaala midab si ay u iftiimiso waddooyinka muruqyada sawirada X-ray. Tuubo khafiif ah, oo jilicsan oo leh kamarad dhamaadka, oo loo yaqaan 'endoscope', ayaa maraa cunaha oo gala mindhicirka yar. Midabku wuxuu galaa waddooyinka iyada oo loo marayo tuubo yar oo madhan, oo loo yaqaan 'catheter', oo loo marayo endoscope. Qalab yar oo loo marayo catheter ayaa sidoo kale loo isticmaali karaa in lagu saaro dhagaxa muruqyada.

Biopsyka beerka waa hab lagu qaado muunad yar oo unug beer ah si loo baadho shaybaadhka. Biopsyka beerka waxaa caadiyan la sameeyaa iyadoo la geliyo irbad khafiif ah maqaarka oo gala beerka.

Faraqsiyada iyo hababka loo isticmaalo baaritaanka cholangitis-ka sclerosis-ka aasaasiga ah waxaa ka mid ah:

• Tijaabada shaqada beerka ee dhiiga. Tijaabada dhiiga ee lagu hubiyo shaqada beerkaaga, oo ay ku jiraan heerarka enzymes-ka beerkaaga, waxay siin kartaa dhakhtarkaaga tilmaamo ku saabsan baaritaankaaga.
• MRI-ga waddooyinka muruqyadaada. Magnetic resonance cholangiopancreatography (koh-lan-jee-o-pan-cree-uh-TOG-ruh-fee) waxay isticmaashaa sawir-qaadista resonance-ka magnetic (MRI) si ay u sameyso sawirro beerkaaga iyo waddooyinka muruqyadaada waxayna tahay tijaabada ugu habboon ee lagu ogaado cholangitis-ka sclerosis-ka aasaasiga ah.
• Biopsyka beerka. Biopsyka beerka waa hab lagu qaado qayb unug beer ah si loo baadho shaybaadhka. Dhakhtarkaagu wuxuu geliyaa irbad maqaarkaaga oo gala beerkaaga si uu u soo saaro muunad unug ah.

Biopsyka beerka wuxuu ka caawin karaa in la ogaado heerka dhaawaca beerkaaga. Tijaabadan waxaa loo isticmaalaa oo kaliya marka baaritaanka cholangitis-ka sclerosis-ka aasaasiga ah wali uu yahay mid aan hubin lahayn ka dib tijaabooyin aan aad u xanuun badneyn.

Sawirada X-ray ee waddooyinka muruqyadaada. Nooc ka mid ah sawirka X-ray ee waddooyinka muruqyada oo loo yaqaan endoscopic retrograde cholangiopancreatography (ERCP) marka lagu daro, ama beddelkeeda, MRI laga yaabo inay lagama maarmaan tahay. Laakiin tijaabadan si dhif ah ayaa loo isticmaalaa baaritaanka sababtoo ah halista dhibaatooyinka.

Si aad u muujiso waddooyinka muruqyadaada sawirka X-ray, dhakhtarkaagu wuxuu isticmaalaa tuubo jilicsan oo hoos loo dhigo cunahaaga si uu u buuxiyo midab meesha mindhicirkaaga yar ee waddooyinka muruqyadaadu ku daadiyaan.

ERCP waa tijaabada ugu habboon haddii calaamadaha iyo astaamaha ay sii socdaan inkastoo aan lahayn wax isbeddel ah oo ku jira MRI. ERCP badanaa waa tijaabada ugu horreysa haddii aadan awoodin inaad hesho MRI sababtoo ah qalab bir ah oo jirkaaga ku jira.

Biopsyka beerka. Biopsyka beerka waa hab lagu qaado qayb unug beer ah si loo baadho shaybaadhka. Dhakhtarkaagu wuxuu geliyaa irbad maqaarkaaga oo gala beerkaaga si uu u soo saaro muunad unug ah.

Biopsyka beerka wuxuu ka caawin karaa in la ogaado heerka dhaawaca beerkaaga. Tijaabadan waxaa loo isticmaalaa oo kaliya marka baaritaanka cholangitis-ka sclerosis-ka aasaasiga ah wali uu yahay mid aan hubin lahayn ka dib tijaabooyin aan aad u xanuun badneyn.