GLP-1 Dose Calculator

Convert your prescribed mg to insulin-syringe units - instantly, privately.

Standard titration schedules

The FDA-labeled starting schedules for semaglutide and tirzepatide - a reference, not a prescription.

Semaglutide - weekly titration

Semaglutide weekly titration schedule
WeekDose
Weeks 1–40.25 mg/wk
Weeks 5–80.5 mg/wk
Weeks 9–121.0 mg/wk
Weeks 13–161.7 mg/wk
Week 17+2.4 mg/wk

Weeks 1–4: Starter dose · Week 17+: Maintenance

Tirzepatide - weekly titration

Tirzepatide weekly titration schedule
WeekDose
Weeks 1–42.5 mg/wk
Weeks 5–85.0 mg/wk
Weeks 9–127.5 mg/wk
Weeks 13–1610 mg/wk
Weeks 17–2012.5 mg/wk
Week 21+15 mg/wk

Weeks 1–4: Starter (not for maintenance) · Week 21+: Maximum dose

Reference-only titration from the FDA label. Your prescriber may adjust timing based on how you tolerate each step.

How GLP-1 dose calculations work

GLP-1 medications are prescribed in milligrams, but compounded medications are often measured using insulin syringes and units. The number of units you inject depends on your medication concentration, usually expressed as mg/mL.

For example, 2.5 mg of tirzepatide will require a different number of syringe units depending on whether your vial concentration is 5 mg/mL, 10 mg/mL, or 20 mg/mL.

This calculator helps convert prescribed GLP-1 doses into accurate injection volumes to reduce confusion and dosing errors.

Related GLP-1 dosing guides

  • GLP-1 dose conversion chart
  • Tirzepatide dosage chart
  • GLP-1 dosage timing and injection guide
  • GLP-1 drug comparisons

If you're switching medications, see our GLP-1 dose conversion chart for approximate equivalence between semaglutide, tirzepatide, liraglutide, and dulaglutide.

Not sure which dose is considered standard maintenance? Review the tirzepatide dosage chart or full GLP-1 titration schedules.

Injection site rotation, timing, and weekly schedules can affect tolerability and consistency. Learn more in our GLP-1 injection guide.

Questions about GLP-1 dosing, side effects, or switching medications?

august is a private AI health companion that can help explain GLP-1 dosing schedules, titration, side effects, injection timing, insurance coverage, and weight loss medications without a clinic visit or copay.

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Frequently Asked Questions

It's a simple converter, built by our clinical team, that turns your prescribed dose in milligrams into the exact number of units to draw on a U-100 insulin syringe.

It depends entirely on the concentration printed on your vial. At 5 mg/mL, 0.25 mg is 5 units. At 2.5 mg/mL, 0.25 mg is 10 units. Always read the label before drawing.

No. Those are brand-name pre-filled pens that deliver fixed doses - no conversion needed. This tool is for compounded vials dispensed by a compounding pharmacy.

Yes. As long as you know the concentration on your vial, the calculator covers the dosing formats used for compounded semaglutide and tirzepatide.

A standard U-100 insulin syringe, where 100 units equal 1 mL. If your syringe says something different, stop and check with your prescriber.

Dose is the medication amount in milligrams (mg). Volume is the liquid you draw, in milliliters (mL). Concentration is the strength - how much medication is in each mL (e.g., 10 mg/mL means 10 mg per mL). The calculator converts between them for you.

Units = (Dose in mg ÷ Concentration in mg/mL) × 100. This assumes a U-100 insulin syringe, where 1 mL = 100 units.

You have two safer options: switch to a larger-barrel syringe, or split the dose into two injections using a higher-concentration vial. Confirm either change with your provider before adjusting.

The number of units you draw is tied to the concentration your pharmacy dispensed. Doses-per-vial and weeks-of-supply are estimates - preparation, dead space, and instructions can shift them. Always verify the concentration printed on your pharmacy label before each injection.

No. This is an educational reference from a doctor-built clinical team - it does not replace a prescriber. Always follow your clinician's instructions and confirm the concentration on your vial before injecting.