Siseduze kangakanani kuze kube nokuphulukiswa kwe-Herpes?

Ukuphulukiswa kweqiniso kwe-herpes akukatholakali okwamanje, kodwa abacwaningi benza intuthuko eqhubekayo. Mhlawumbe ulapha ngoba wena noma omunye umuntu omkhathalelayo utholakale ne-herpes, futhi ufuna ukwazi ukuthi kukhona yini ithemba langempela esilibheke. Impendulo emfushane yebo, ososayensi basebenzela izindlela eziningana ezinombono omuhle ezingase ziphelise igciwane emzimbeni wakho ngelinye ilanga. Njengamanje, sinezindlela zokwelapha ezisebenza kahle kakhulu ezigcina igciwane lithule futhi likusize uphile impilo egcwele nenempilo.

Ukuphulukiswa Kwe-Herpes Kusho Njani Ngempela?

Ukuphulukiswa kusho ukukhipha ngokuphelele igciwane le-herpes emzimbeni wakho ukuze lingabuyeli. Lokhu kuhlukile kulokho okwenziwa imithi yamanje, okungukuthi ukugcina igciwane ngaphansi kokulawula. Igciwane le-herpes simplex, noma i-HSV, liyazifihla emizileni yenzwa lapho amasosha omzimba wakho nemithi eminingi ayikwazi ukukulifikisela khona. Liyohlala lingasebenzi, noma lilale, kuze kube yilapho kukhona okulenza livuke futhi libangele ukuqubuka.

Imithi yamanje ye-antiviral efana ne-acyclovir, i-valacyclovir, ne-famciclovir isebenza kahle kakhulu ekumisyeni igciwane ekwandeni. Kunciphisa ukuqubuka, kunciphisa izimpawu, futhi kunciphisa ithuba lokudlulisa igciwane komunye umuntu. Kodwa akukhiphi igciwane emizileni yakho yenzwa. Yilokho ososayensi abazama ukukushintsha.

Kungani I-Herpes Inzima Kangaka Ukuyiphulukisa?

Igciwane le-herpes lihlakaniphe ngokwedlulele ekuzifihleni. Uma selingene emzimbeni wakho, liyolunga emizileni yenzwa eseduze nomgogodla wakho futhi liyolala khona. Le mizila yenzwa injengemikhukhu evikelekile lapho igciwane lingahlala khona lingasebenzi izinyanga noma ngisho neminyaka. Amasosha akho omzimba ayahlola umzimba wakho efuna izitha, kodwa anzima kakhulu ukubona amagciwane acashile ngaphakathi emizileni yenzwa.

Lapho igciwane lingasebenzi, alikhiqizi cishe amaproteni noma into ebhalwe nge-DNA. Lokho kusho ukuthi amasosha akho omzimba awuliboni njengengozi. Lokho kusho futhi ukuthi imithi eminingi ye-antiviral, esebenza ngokumisa igciwane ekuzikopela, ayinawo umgomo. Igciwane alizikopeli lapho lilala.

Enye inkinga ukuthi i-herpes DNA iyazihlanganisa nento ebhalwe nge-DNA yemizila yakho yenzwa. Iba yingxenye yeseli ngendlela eyenza kube nzima kakhulu ukuyikhipha ngaphandle kokulimaza inzwa ngokwayo. Ososayensi badinga ukuthola indlela yokuvusa zonke igciwane elifihliwe futhi bayibulale, noma ukusika i-viral DNA ngaphandle kokulimaza amaseli akho anempilo.

Yiziphi Izindlela Zokwelapha Esizinazo Njengamanje?

Ngaphambi kokuba sikhulume ngokuphulukiswa esizofika esikhathini esizayo, kuyasiza ukuqonda ukuthi yini esebenza kakade kwezigidi zabantu. Imithi yamanje ye-antiviral iphephile, iyasebenza, futhi iyatholakala kabanzi. Inganciphisa kakhulu inani lezikhathi zokuqubuka ozithola futhi yenze izimpawu zibe mbulalwane kakhulu lapho zenzeka. Abantu abaningi bathatha imithi yansuku zonke yokuvimbela, okusho ukuthatha iphilisi njalo ukuze kugcinwe igciwane lithule.

Le mithi ingase futhi inciphise ubungozi bokudlulisa i-herpes kumngane cishe ngamaphesenti angama-50 lapho ihlanganiswa namanye amasu okuvimbela. Lokho kumehluko obalulekile. Uma uphila ne-herpes njengamanje, unamathuluzi asebenzayo. Akawuphulukisi ukutheleleka, kodwa akukunika ukulawula kuko.

OSOSAYENSI Basebenza Ngani Njengamanje?

Izindlela Zokwelapha Zokuhlela Amageni

Ukuhlela amageni kungenye yezindawo ezijabulisa kakhulu zocwaningo lwe-herpes. Ososayensi basebenzisa amathuluzi afana ne-CRISPR, esebenza njengezinwele zemishini, ukusika i-herpes DNA emizileni yenzwa ethelelekilayo. Ezifundweni zase-laboratory kanye namamodeli ezilwane, abacwaningi bakwazile ukususa izingxenye ze-viral DNA futhi bayeka igciwane ukuba livuselelwe. Le ndlela isasezinkambeni zayo zokuqala, kodwa imiphumela kuze kube manje iyakhuthaza.

Inkinga enkulu ekuhleleni amageni ukuletha ukwelashwa ngokuphepha kuyo yonke imizila yenzwa ephethe igciwane. Imizila isakazeke kulo lonke umzimba wakho, futhi ukufinyelela kuwo wonke amangqamuzana athelelekile akulula. Ososayensi bahlola amagciwane akhethekile, abizwa ngokuthi ama-vectors, angaqupha amathuluzi okuhlela amageni emizileni yenzwa ngaphandle kokubangela ukulimala. Eminye yalezi zahlulo zokulethwa kwezinto isivele ihlolwa ezilwaneni.

Izivivinyo zabantu zezindlela zokwelapha zokuhlela amageni cishe zisanyamalala iminyaka embalwa. Abacwaningi kumele baqinisekise ukuthi ukwelashwa kuphephile, kuyasebenza, futhi akulimazi i-DNA enempilo ngengozi. Kodwa le ndlela inamandla angempela okuba ukuphulukisa kwangempela.

Izindlela Zokwelapha Ezisuselwe Emzimbeni

Elinye isu elinokubona ngamehlo eliqinisa amasosha omzimba wakho ukuze akwazi ukuthola futhi aqede igciwane elifihliwe. Abanye abacwaningi bakha izimali zokugoma ezifundisa amasosha omzimba wakho ukuthi aqaphe futhi ahlasela imizila yenzwa etheleleke yi-herpes. Ngokungafani nezimali zokugoma ezivimbelayo, ozithola ngaphambi kokuba utheleleke, izimali zokwelapha zinikezwa ngemuva kokuba usuvele unalo igciwane.

Lezi zimali zisebenza ngokufundisa ama-T cells akho, uhlobo lwe-immune cell, ukuthi zibone amaproteni athile akhiqizwa igciwane le-herpes. Uma isiqeqeshwe, ama-T cells akho angakwazi ukuhambela umzimba wakho futhi aqede noma iyiphi imizila yenzwa eqala ukukhiqiza amaproteni egciwane. Izifundo zokuqala zibonise ukuthi ezinye izimali zokwelapha zinganciphisa inani lezikhathi zokuqubuka futhi zinciphise inani legciwane emzimbeni.

Imali eyodwa yokugoma evivinywa ebizwa ngokuthi imali ye-DNA ikhombise isethembiso ezifundweni zezilwane. Isebenzisa izingxenye ze-herpes DNA ukulungiselela amasosha omzimba ngaphandle kokubangela ukutheleleka. Enye indlela isebenzisa amagciwane aphilayo kodwa abuthakathaka ukuvusa ukuphendula okuqinile komzimba. Izivivinyo zabantu ziyasebenza kwezinye zezimali zokugoma, futhi imiphumela kufanele itholakale eminyakeni embalwa ezayo.

Imithi Ephukisa Igciwane

Abanye abacwaningi bathatha indlela ehlukile ngokuzama ukuvusa igciwane elilalayo. Umqondo uwukusebenzisa imithi ephusha igciwane ukuthi liqale ukuzikopela futhi. Uma igciwane selisebenza, liyoba sengozini yezindlela zokwelapha ze-antiviral namasosha omzimba wakho. Le ndlela ngezinye izikhathi ibizwa ngokuthi i-shock and kill.

Ezifundweni zase-laboratory, ososayensi bahlole imithi engavusa kabusha i-herpes emizileni yenzwa. Lapho ihlanganiswa nemithi ye-antiviral eqinile, le ndlela inciphise inani legciwane elilalayo. Inkinga yokuqinisekisa ukuthi ukwelashwa kuvusa zonke igciwane elifihliwe ngesikhathi esisodwa, hhayi kuphela ezinye zazo. Noma ngabe amakhophi ambalwa egciwane asele eyimfihlo, angabanga ukuqubuka futhi esikhathini esizayo.

Le ndlela isaxoxwa ezilwaneni, futhi kuyothatha isikhathi ukubona ukuthi iyasebenza yini kubantu ngokuphepha. Abacwaningi kudingeka baqinisekise ukuthi ukuvusa igciwane akubangi ukuqubuka okunzima noma ezinye izinkinga.

Izimali Zokugoma Ezivimbelayo

Noma kungewona ukuphulukiswa, izimali zokugoma ezivimbelayo zingamiswa ukutheleleka kwe-herpes okwenzeka kuqala. Amaqembu amaningana asebenza ezimalini zokugoma ezizovikela abantu abangakaze bahlangane negciwane. Uma ziphumelela, lezi zimali zokugoma zinganciphisa kakhulu inani lokutheleleka okusha unyaka ngamunye.

Ukuthuthukisa imali yokugoma ye-herpes kube inkinga ngoba igciwane lihle kakhulu ekugwenqeni amasosha omzimba. Izivivinyo ezedlule zemali yokugoma azizange ziphumelele, kodwa ososayensi bafunde kakhulu kulokho kuzama. Imiklamo emisha yemali yokugoma isebenzisa ubuchwepheshe obusezingeni eliphezulu futhi ihlose izingxenye ezahlukene zegciwane. Ezinye izivivinyo zigxile ezimalini zokugoma ezivikela kokubili i-HSV 1 ne-HSV 2, izinhlobo ezimbili eziyinhloko ze-herpes.

Kungakanani Isikhathi Esisele Kuze Kuthi Kutholakale Ukuphulukiswa?

Izivivinyo zezinhlangano zenziwa ngezinyathelo. Izivivinyo zeSigaba 1 zihlobanisa ukuphepha eqenjini elincane labantu. Izivivinyo zeSigaba 2 zibheka ukuthi ukwelashwa kuyasebenza yini nokuthi yini umthamo ongcono kakhulu. Izivivinyo zeSigaba 3 zibandakanya izinkulungwane zabantu futhi ziqhathanisa ukwelashwa okusha nezinketho zamanje. Isinyathelo ngasinye singathatha iminyaka embalwa. Ngemva kwalokho, iziphathimandla zokulawula njenge-FDA zibuyekeza idatha ngaphambi kokugunyaza ukwelashwa.

Izindlela zokuhlela amageni nezimali zokugoma ezikwelapha njengamanje sezinkambeni zokuqala kakhulu zokuhlolwa. Ezinye izindlela zokwelapha ezisekelwa umzimba zifinyelele Ezivivinyweni zeSigaba 2, okusho ukuthi abacwaningi baqala ukubona ukuthi ziyasebenza yini ebantwini. Kungenzeka ukuthi enye yalezi zindlela ingagunyazwa eminyakeni eyishumi ezayo, kodwa akukho iziqinisekiso.

Yini Ongayenza Ngenkathi Ulindele Ukuphulukiswa?

Ukuphila ne-herpes njengamanje akusho ukuthi ubeke impilo yakho eceleni kuze kube yilapho kufika ukuphulukiswa. Unayo izinketho ezisebenzayo zokulawula izimpawu nokuvikela impilo yakho. Ukuthatha imithi yansuku zonke ye-antiviral kunganciphisa ukuqubuka futhi kunciphise ubungozi bokudlulisa. Abantu abaningi bathola ukuthi ukuqubuka kwabo kuba mbalwa ngokuhamba kwesikhathi, ngisho nangaphandle kokuphulukiswa.

Ukucindezeleka, ukugula, nokungabi nokulala kungavusa ukuqubuka, ngakho-ke ukunakekela impilo yakho yonke kubalulekile. Ukudla kahle, ukulala ngokwanele, nokulawula ukucindezeleka kungasiza ukugcina igciwane lithule. Ungase futhi uthole kusiza ukuxhumana neqembu labasekelayo noma umeluleki oqonda ukuthi udlula ngani. I-Herpes iyinto evamile kakhulu, ethinta cishe umuntu oyedwa kweyisithupha, futhi awuwedwa.

Kuyafaneleka futhi ukuhlala unolwazi mayelana nocwaningo olusha. Izivivinyo zezinhlangano zihlala zifuna abahlanganyeli, futhi ukujoyina isivivinyo kungakunika ukufinyelela ezindleleni zokwelapha ezisezingeni eliphezulu ngenkathi kusiza ososayensi ukuba basondelane nokuphulukiswa. Ungabuza udokotela wakho ukuthi kukhona yini izivivinyo ongase ufanelekele zona.

Isiphetho

Ukuntuleka kokuphulukiswa okwamanje akusho ukuthi akukho themba. Ososayensi benza intuthuko yangempela, futhi izindlela ezihlolwayo zisezingeni eliphakeme kakhulu kunanoma yini esike sayibona ngaphambili. Ukuhlela amageni, izindlela zokwelapha ezisekelwa umzimba, nezimali zokugoma ezikwelapha zonke zinamandla okuguqula indawo yokwelashwa kwe-herpes. Ezinye zalawa macebo zingasebenza ndawonye ukuze zinikeze imiphumela engcono.

Ngenkathi ulindele, khumbula ukuthi i-herpes isimo esingalawuleka. Ayikuchazeli, futhi akudingeki ikukhawulele impilo yakho. Izigidi zabantu abane-herpes zinobudlelwano obugcwele, imindeni enempilo, nemisebenzi ephumelelayo. Izindlela zokwelapha ezitholakala namuhla ziyasebenza, futhi izinketho ezintsha seziseduze.

Ufanele ulwazi olunembayo, ukunakekelwa okunomusa, nethemba lekusasa. Qhubeka ubuzwa imibuzo, hlala uxhumene nomhlinzeki wakho wezempilo, futhi uzinakekele. Ukuphulukiswa kungase kungakabibikho, kodwa kusondele kunanini ngaphambili, futhi awulindele wedwa.