Calciphylaxis

I-Calciphylaxis (kal-sih-fuh-LAK-sis) yisifo esingavamile, esinzima. Ihilela ukwakheka kwe-calcium emathafeni egazi amancane ezinhlangothini zamafutha nesikhumba.

Izimpawu ze-Calciphylaxis zihlanganisa iziqu egazini, ama-lumps ngaphansi kwesikhumba kanye nezihlamba ezivulekile ezibuhlungu ezibizwa ngokuthi ama-ulcers. Uma i-ulcer igula, ingaba yingozi eyingozi empilweni.

Imbangela eqondile ye-calciphylaxis ayicaci. Kepha abantu abanesifo ngokuvamile baba nokuhluleka kwempilo yokukhipha amanzi. Leso yisimo lapho izinso zingasasebenzi kahle. Ngokuvamile, laba bantu bafumana nezinye izindlela zokwelapha ukuhluleka kwempilo yokukhipha amanzi njengokwelashwa kwe-dialysis noma ukutshalwa kwezinso. I-Calciphylaxis ingenzeka kubantu abangenayo i-kidney disease.

Izindlela zokwelapha i-Calciphylaxis zihlanganisa imithi ehlukahlukene, izinqubo nokuhlinzwa. Ukwelashwa kungasiza ukuvimbela iziqu egazini kanye nokutheleleka, kunciphisa ukwakheka kwe-calcium, ukwelapha ama-sores, nokunciphisa ubuhlungu.

Izimpawu ze-Calciphylaxis zifaka phakathi:

• Izindlela ezinkulu ezifana ne-net ekhulwini ezingase zibonakale zibomvu oluhlaza okwesibhakabhaka.
• Ama-lumps ajulile, abuhlungu ekhulwini angaba yizilonda. Izilonda zivame ukuba neqanda elimnyama-nsundu elingahlangi lodwa. Izilonda zivame ukuvela ezindaweni ezinamanoni amaningi, njengesisu, ithambo, uhlangothi, kanye nebele. Kodwa zingakha noma kuphi.
• Ukutheleleka okuvela ezilondeni ezingapholi.

Imbangela eqondile ye-calciphylaxis ayaziwa. Lesi sifo sihilela ukuqongelelana kwe-calcium ezingxenyeni ezincane ze-arteries ezindaweni ezinamanoni kanye nokwesikhumba.

Abantu abaningi ababa ne-calciphylaxis nabo bane-ukwehluleka kwesibindi noma bathola i-dialysis. Akwaziwa ukuthi kungani abantu abane-ukwehluleka kwesibindi noma abantu abamukela i-dialysis baphezu kokutholakala kwe-calciphylaxis.

Kwabanye abantu, ukuqongelelana kwe-calcium ku-calciphylaxis kuhlotshaniswa nezinye izitho ezincane ezinqeni ebizwa ngokuthi yi-parathyroid glands. Uma lezi zinso zikhulula ama-parathyroid hormones amaningi kakhulu, lokho kungabangela i-calcium ukuthi iqoqane. Kodwa-ke, lo xhumaniso alucaci. Abantu abaningi abane-parathyroid glands ezisebenza kakhulu abayitholi i-calciphylaxis. Futhi abantu abaningi abane-ukwehluleka kwesibindi ne-calciphylaxis abanazo i-parathyroid glands ezisebenza kakhulu.

Faktha ezinye ezibukeka sengathi zidlalela indima ku-calciphylaxis zihlanganisa:

• Ukuthambekela okukhulu kwegazi ukuthi liqine. Ama-blood clots angasusa amanoni kanye nokwesikhumba i-oksijini nokudla.
• Ukugeleza kwegazi okunciphisiwe kuma-arteries amancane, okungabangela ama-lumps esikhumba nama-ulcers.
• Ukuqina noma ukwenziwa ama-scars ethishu, okuthiwa futhi i-fibrosis.
• Ukonakala okuqhubekayo kwe-layer ecwebezelayo yamashelu athi abumba imithambo yegazi. Lokhu kubizwa futhi ngokuthi i-vascular endothelial injury.
• Ukukhuluphala, okuthiwa i-inflammation, emzimbeni.

I-Calciphylaxis ihlukanisa kakhulu abantu abanehluleko lezinso. Amanye ama-risk factor afaka phakathi:

• Ukuba owesifazane.
• Ukukhuluphala.
• I-Diabetes mellitus.
• I-Liver failure, lapho isibindi siyeka ukusebenza njengoba kufanele.
• Umlando wokwelashwa nge-dialysis. Le nqubo isusa ukhukhwini kanye noketshezi olongeziwe egazini uma izinso zingasakwazi.
• Ukuthambekela okukhulu kwegazi lokuhlanganisa, okuthiwa yi-hypercoagulable state.
• Ukungalingani emzimbeni wamaminerali i-calcium noma i-phosphate, noma i-protein albumin.
• Amanye amayeza, afana ne-warfarin (Jantoven), ama-calcium-binding agents kanye nama-corticosteroids.

Izinkinga ze-calciphylaxis zihlanganisa:

• Ubuhlungu obukhulu.
• Izihlamba ezinkulu, ezijulile ezingapholi zodwa.
• Ukutheleleka kwegazi.
• Ukufa, ikakhulu ngenxa yokutheleleka noma ukwehluleka komzimba.

Ngokuvamile, ithemba labantu abane-calciphylaxis alihle. Ukufumana nokwelapha noma yikuphi ukutheleleka ngokushesha kubalulekile ekuvimbeni izinkinga ezinkulu.

Asikho isindlela ecacile yokuvimbela i-calciphylaxis. Kodwa uma use-dialysis noma une-renal function ephansi ngenxa yesifo sikashukela esiqhubekayo esiphambili, kubalulekile ukuqapha amazinga e-calcium ne-phosphorus egazini. Ukuqapha amazinga e-phosphorus egazini kuvame ukuba yingxaki. Uchwepheshe wakho wezokunakekelwa kwezempilo angase akwenze uthathe imithi ngesikhathi sokudla. Ungase futhi udinga ukuvimba ukudla okuthile okuphezulu ku-phosphorus. Kubaluleke kakhulu ukulandela imiyalo yochwepheshe wakho wezokunakekelwa kwezempilo futhi uye kuwo wonke ama-checkup okunakekelwa kwezempilo okulandelayo. Uma une-calciphylaxis, iqembu lakho lokunakekelwa kwezempilo likusize ukuvimbela ukutheleleka kwamacwebe noma ezinye izinkinga. Ungase udinga ukufaka izembozo zezopholi ezikhethekile noma uhlanze ama-ulcers nsuku zonke ukuvimbela amagciwane okuthiwa yi-bacteria ekukhuleni.

Ukuxilongwa kuhilela ukubona ukuthi i-calciphylaxis yiyona yona ebangela izimpawu zakho. Uchwepheshe wakho wezokunakekelwa kwezempilo uhlola umlando wakho wezempilo, ubuze ngezimpawu zakho futhi akunikeze ukuhlolwa komzimba.

Ungase futhi udinga ukuhlolwa okunjengokulandelayo:

• I-biopsy yesikhumba. Ngesikhathi senqubo, uchwepheshe wakho wezokunakekelwa kwezempilo ukhumula isampula encane yethishu endaweni yesikhumba esithintekile. Khona-ke, i-lab ihlola isampula.
• Ukuhlolwa kwegazi. I-lab ingalinganisa izinto ezihlukahlukene egazini lakho. Lokhu kuhlanganisa i-creatinine, i-calcium, i-phosphorus, i-parathyroid hormone ne-vitamin D. Imiphumela iyasiza iqembu lakho lokunakekelwa kwezempilo ukuthi lihlole ukuthi ama-kidneys akho asebenza kahle kangakanani.
• Ukuhlolwa kwezithombe. Lokhu kungaba usizo uma imiphumela ye-biopsy ingacaci noma uma i-biopsy ingenziwa. I-X-rays ingabonisa ukwakheka kwe-calcium emithanjeni yegazi. Lokhu kwakheka kuyinto evamile ku-calciphylaxis nakwezinye izifo zezinso eziphambili.