Ukuthi yini i-Calciphylaxis? Izimpawu, Izimbangela, & Ukwelashwa

I-Calciphylaxis iyisimo esingavamile kodwa esibuhlungu lapho i-calcium iqala ukwakheka ezinhlungwini zegazi ezincane ngaphansi kwesikhumba sakho nasemafutheni. Lokhu kukwakheka kuvimba ukugeleza kwegazi futhi kubangele amanxeba esikhumba abhlungu angaba yingozi uma engawelashwa ngokushesha.

Nakuba igama lingase lizwakale liyesabekisa, ukuqonda lesi simo kungakusiza ukuthi uqaphele izimpawu zokuqala bese ufuna ukunakekelwa kwezokwelapha ngokushesha. Imikhakha eminingi ivela kubantu abanesifo sezinso, kodwa i-calciphylaxis ingathinta noma ubani ngaphansi kwezimo ezithile.

Iyini i-calciphylaxis?

I-Calciphylaxis ivela lapho ama-calcium deposits eqala ukwakheka ngaphakathi odongeni lwezinhlungwini zegazi ezincane ngaphansi kwesikhumba sakho. La ma-deposits asebenza njengamithi emincane yomgwaqo, evikela ukunikezwa kwegazi esikhumbeni sakho nasefutheni elingaphansi.

Uma isikhumba sakho singatholi igazi elanele, siqala ukufa, sidala amanxeba abhlungu abukeka njengamanxeba ajulile noma ama-patches amnyama. Igama lezokwelapha lale nqubo yi-“calcific uremic arteriolopathy,” kodwa odokotela abaningi bayibiza nje nge-calciphylaxis.

Lesi simo sivame ukubathinta abantu abanamazinga ezinso angasebenzi kahle, kodwa ngezinye izikhathi singathuthukiswa kubantu abanamazinga ezinso ajwayelekile. Amanxeba avame ukuvela ezindaweni ezinamanoni amaningi, njengezinyawo zakho, izinti, noma isisu.

Ziyini izimpawu ze-calciphylaxis?

Izimpawu zokuqala ze-calciphylaxis zivame ukuqala njengokushintsha kwesikhumba okungase kubonakale kuncane ekuqaleni. Noma kunjalo, lezi zimpawu zingathuthuka ngokushesha futhi zibe nzima kakhulu.

Izimpawu zokuqala ongazibona zifaka:

• Ama-patches abomvu noma aluhlaza okwesibhakabhaka esikhumbeni sakho azwa ebuhlungu uma ubathinta
• Isikumba esizwa siqinile noma siqinisile ezindaweni ezithile
• Iphethini efana ne-net yokushintsha kombala esikhumbeni sakho
• Isikumba esiba nomuzwa wokuthi sibuhlungu kakhulu, ngisho nokubamba okulula

Njengoba isimo sithuthuka, izimpawu ezinzima kakhulu zivela:

• Amanxeba avulekile noma amanxeba angapholi
• Ama-patches amnyama noma amnyama lapho isikumba sifile khona
• Ubuhlungu obukhulu obungadinga imithi ebuhlungu enamandla
• Amanxeba athuthukisa imigoqo ehlala iqinile
• Izimpawu zokutheleleka njengobushushu, ubuhlungu obukhulu, noma i-pus

Ubuhlungu obuvela ku-calciphylaxis buvame ukubizwa ngokuthi bubi kakhulu futhi bungathinta impilo yakho yansuku zonke. Abantu abaningi bathola ukuthi ngisho nokubamba okulula noma ukuhamba kwenza ubuhlungu bube bukhulu, kungakho ukunakekelwa kwezokwelapha kwasekuqaleni kubaluleke kangaka.

Ziyini izimbangela ze-calciphylaxis?

I-Calciphylaxis ithuthuka lapho izinga le-calcium ne-phosphate emzimbeni wakho liyaphazanyiswa, okuholela ekuqaleni kwama-calcium deposits odongeni lwezinhlungwini zegazi. Lokhu kungalingani kuvame ukwenzeka ngoba izinso zakho azikwazi ukuhlanza kahle lezi mineral egazini lakho.

Izimbangela eziyinhloko eziyinhloko zifaka:

• Isifo sezinso esiphelile, ikakhulukazi kubantu abase-dialysis
• Ukwehluleka okukhulu kwezinso okuthinta ukucubungula kwe-mineral
• Amaglands e-parathyroid asebenza kakhulu akhipha i-parathyroid hormone eningi kakhulu
• Ukusetshenziswa isikhathi eside kwemithi ehlanza igazi njenge-warfarin
• Ezinye izimo ze-autoimmune ezithinta izinhlungwini zegazi

Izimbangela ezingavamile odokotela abazibonile zifaka:

• Isifo sesibindi esithinta ukukhiqizwa kwamaprotheni
• Ezinye izinhlobo zomdlavuza, ikakhulukazi umdlavuza wegazi
• Ezinye imithi ethinta ukuguqulwa kwe-calcium
• Ukondleka okubi noma ukuphazamiseka kokudla
• Isifo se-inflammatory bowel disease ezimweni ezingavamile

Ngezinye izikhathi i-calciphylaxis ithuthuka ngaphandle kwesizathu esicacile esiyinhloko, odokotela abakubiza ngokuthi “idiopathic” calciphylaxis. Lo mkhuba awuvamile kodwa ungaba nzima kakhulu futhi udinga indlela efanayo yokwelapha ephuthumayo.

Nini kufanele ubona udokotela nge-calciphylaxis?

Kufanele ufuna ukunakekelwa kwezokwelapha ngokushesha uma ubona ukushintsha kwesikhumba okubuhlungu, ikakhulukazi uma unesifo sezinso noma ezinye izinto ezingase zikubangele.

Xhumana nodokotela wakho ngokushesha uma uthuthukisa:

• Ama-patches abomvu, aluhlaza okwesibhakabhaka, noma amnyama esikhumbeni sakho
• Isikumba esizwa siqinile noma sithuthukisa iphethini efana ne-net
• Amanxeba avulekile angapholi noma aqhubeka eba sibi
• Ubuhlungu besikhumba obukhulu obuphazamisa imisebenzi yansuku zonke

Shaya ucingo ukuze uthole ukunakekelwa okuphaphandwayo uma uhlangabezana nokuthi:

• Izimpawu zokutheleleka okukhulu njengobushushu, ukuthamba, noma ukungakhululeki
• Ukushintsha kwesikhumba okusabalala ngokushesha noma amanxeba amasha
• Ubuhlungu obukhulu obungalawulwa yimithi ebizwe
• Ukushintsha kwesikhumba uma use-dialysis noma unesifo sezinso esibuhlungu

Ungalindi ukubona ukuthi izimpawu ziyathuthuka ngokwazo. I-Calciphylaxis ingathuthuka ngokushesha, futhi ukungenelela kwasekuqaleni kukunika ithuba elihle kakhulu lokwelashwa okuphumelelayo nokuphulukisa.

Ziyini izinto ezingase zikubangele i-calciphylaxis?

Ukuqonda izinto ezingase zikubangele kungakusiza wena neqembu lakho lokunakekelwa kwezokwelapha ukubuka izimpawu zokuqala ze-calciphylaxis. Nakuba noma ubani angathuthukisa lesi simo, izinto ezithile zikhuphula kakhulu amathuba akho.

Izinto eziyinhloko ezingase zikubangele zifaka:

• Isifo sezinso esiphelile esidinga i-dialysis
• Amazinga aphezulu e-calcium, i-phosphate, noma i-parathyroid hormone egazini lakho
• Ukuba owesifazane, ikakhulukazi ngemuva kwe-menopause
• Ukuba nesifo sikashukela kanye nesifo sezinso
• Ukusetshenziswa isikhathi eside kwemithi ehlanza igazi njenge-warfarin
• Ukukhuluphala, okuthinta ukugeleza kwegazi nokuphulukisa

Ezinye izinto ezingase zikubangele odokotela abazibonile zifaka:

• Ukusebenzisa imithi ethile ehlanganisa i-phosphate
• Ukuba uthole ukutshalwa kwezinso esikhathini esidlule
• Amazinga aphansi eprotheni ebizwa nge-albumin egazini lakho
• Izimo ze-autoimmune ezithinta izinhlungwini zegazi
• Umbhalo wangaphambili wegazi elikhulu noma izinkinga zokujikeleza

Uma unezinto eziningi ezingase zikubangele, iqembu lakho lokunakekelwa kwezokwelapha lizokunaka kakhulu ngokushintsha kwesikhumba. Ukuhlolwa okuvamile nokwenziwa kwezivivinyo zegazi kungasiza ukubamba izinkinga kwasekuqaleni lapho ukwelashwa kuphumelela kakhulu.

Ziyini izinhlanganisela ezingase zenzeke nge-calciphylaxis?

I-Calciphylaxis ingabangela izinhlanganisela ezinzima ezithinta impilo yakho yamanje nokuphila kwakho kwesikhathi eside. Ukuqonda lezi zinhlanganisela ezingase zenzeke kusiza ukuchaza ukuthi kungani ukwelashwa kwasekuqaleni kubaluleke kangaka.

Izinhlanganisela ezinkulu kakhulu zifaka:

• Ukutheleleka okukhulu okungasabalala egazini lakho
• I-sepsis, impendulo eyingozi ekuthelelekeni
• Izindawo ezinkulu zokufa kwesikhumba ezidinga ukususwa ngokusebenza
• Ubuhlungu obuhlala njalo obuthinta kakhulu ikhwalithi yempilo
• Ukuphola okubi kwamanxeba okuholela ekulimala okungapheli

Izinhlanganisela ezingavamile kodwa ezinzima zingafaka:

• Izinkinga zenhliziyo uma ama-calcium deposits ethinta izinhlungwini zegazi zenhliziyo
• Izinkinga zamalunga uma isimo sithinta izinhlungwini zegazi lapho
• Izinkinga zokudla ngenxa yesifo esingapheli nobuhlungu
• Usizi nokukhathazeka okuhlobene nobuhlungu obuhlala njalo nokukhubazeka
• Ukungena engozini yokufuduka, ikakhulukazi ngonyaka wokuqala ngemuva kokuxilongwa

Izindaba ezinhle ukuthi ukuqaphela kwasekuqaleni nokwelashwa kungavimbela izinhlanganisela eziningi. Ukusebenza eduze neqembu lakho lokunakekelwa kwezokwelapha nokulandela izeluleko zokwelashwa kukunika ithuba elihle kakhulu lokuba nemiphumela emihle.

I-calciphylaxis ixilongwa kanjani?

Ukuxilonga i-calciphylaxis kudinga ukuhlanganiswa kokuhlola isikhumba sakho, ukubukeza umlando wakho wezokwelapha, nokwenza izivivinyo ezithile. Udokotela wakho uzobheka ukubonakala okuvamile kokushintsha kwesikhumba kanye nezinto ezingase zikubangele.

Inqubo yokuxilonga ivame ukufaka:

• Ukuhlolwa komzimba okuphelele kwesikhumba sakho nanoma yimanxeba
• Ukubukeza imithi yakho nezimo zezokwelapha
• Izivivinyo zegazi zokuhlola amazinga e-calcium, i-phosphate, ne-parathyroid hormone
• I-biopsy yesikhumba ukubuka ama-calcium deposits ezinhlungwini zegazi
• Izivivinyo ze-imaging njenge-X-rays ukubona ama-calcium deposits

Ngezinye izikhathi kungadingwa izivivinyo ezengeziwe:

• I-bone scans ukuhlola ama-calcium deposits kulo lonke umzimba wakho
• Izivivinyo zokuhlola ukuthi izinso zakho zisebenza kangcono kangakanani
• Ama-cultures amanxeba ukuhlola ukutheleleka
• Ama-stains akhethekile emasampulini e-biopsy ukuqinisekisa ukuxilongwa

Ukuthola ukuxilongwa okuchane kungaqeda isikhathi ngoba i-calciphylaxis ingabonakala ifana nezinye izimo zesikhumba. Udokotela wakho angadinga ukukhipha ezinye izimbangela zamanxeba esikhumba ngaphambi kokuqinisekisa ukuxilongwa.

Ukuphathwa kwe-calciphylaxis kuyini?

Ukuphathwa kwe-calciphylaxis kugxile ekuvimbeni ukuqala kwama-calcium deposits, ukuphatha ubuhlungu, nokusiza amanxeba akhona ukuphulukisa. Lokhu ngokuvamile kudinga iqembu elihlanganisa izinhlobo eziningi zezazi.

Izindlela eziyinhloko zokwelapha zifaka:

• Ukuyeka imithi engase ibe nomthamo wokwakheka kwe-calcium
• Ukulawula amazinga e-calcium ne-phosphate egazini lakho
• Ukusebenzisa imithi ebizwa nge-calcimimetics ukunciphisa i-parathyroid hormone
• Ukukhathalelwa kwamanxeba ngezembatho ezikhethekile nokuhlanza
• Ukuphathwa kobuhlungu ngemithi efanele

Ukuphathwa okuthuthukile okungase kunconywe kufaka:

• I-sodium thiosulfate injections ukusiza ukuxazulula ama-calcium deposits
• I-hyperbaric oxygen therapy ukuthuthukisa ukuphulukisa
• Ukukhipha ithishu efile uma kudingeka
• Ukwenza izinguquko ku-dialysis uma uthola ukwelashwa kokufakwa kwezinso
• Ukuphathwa kwezimo eziyinhloko ezingase zibe nomthamo

Uhlelo lwakho lokwelashwa luzokwenziwa ngokuvumelana nesimo sakho esithile futhi lungashintsha njengoba isimo sakho siphulukisa noma uma izinhlanganisela zithuthuka. Ukubonisana okuvamile kubalulekile ukuqapha intuthuko yakho nokwenza izinguquko zokwelapha uma kudingeka.

Ungayiphatha kanjani i-calciphylaxis ekhaya?

Ukukhathalelwa ekhaya kudlala indima ebalulekile ekuphatheni i-calciphylaxis, kodwa kufanele kuhlale kuhambisana nokuphathwa kwezokwelapha kochwepheshe. Iqembu lakho lokunakekelwa kwezokwelapha lizonika imiyalo ekhethekile ngokuvumelana nezidingo zakho.

Izinyathelo ezibalulekile zokunakekelwa ekhaya zifaka:

• Ukulandela imiyalo yokunakekelwa kwamanxeba ngokunembile njengoba kunqunyiwe
• Ukuthatha yonke imithi njengoba kunqunyiwe, ngisho noma uzizwa kangcono
• Ukuhlanza amanxeba awomile phakathi kokushintsha kwembatho
• Ukuvikela ukwenzakala noma ukulimala ezindaweni zesikhumba ezithintekile
• Ukuqapha izimpawu zokutheleleka njengobuningi bobuhlungu noma ubushushu

Ukukhathalelwa okuqhubekayo ekhaya kungafaka:

• Ukusebenzisa imithi ebuhlungu njengoba kunqunyiwe
• Ukudla ukudla okusekela ukuphulukisa, uma kunconywe
• Ukuhlala unomswakama ngaphandle uma unemikhawulo yamanzi
• Ukuhamba okulula nokubeka ukuvimbela ukulimala kwesikhumba okwengeziwe
• Ukugcina ukubonisana okuqhubekayo nemihla yokuhlolwa kwegazi

Ungalokothi uzame ukwelapha amanxeba e-calciphylaxis wedwa noma usebenzise izindlela zokwelapha zasekhaya ngaphandle kokuxoxa nawo iqembu lakho lokunakekelwa kwezokwelapha. Ukubhekwa kwezokwelapha okufanele kubalulekile ukuphulukisa okuvikelekile nokuphumelelayo.

Kufanele ulungiselele kanjani i-aphoyintimenti yakho nodokotela?

Ukulungiselela i-aphoyintimenti yakho kungasiza ukuqinisekisa ukuthi uthola ukunakekelwa okuphelele ngangokunokwenzeka. Ukuba nolwazi olufanele kulungele ukusiza udokotela wakho ukwenza izinqumo zokwelapha ezinembile.

Ngaphambi kwe-aphoyintimenti yakho, buthana:

• Uhlu oluphelele lwazo zonke imithi, kufaka phakathi imithi yokuthengwa ngaphandle komthetho kanye nezinhlanganisela
• Umbhalo wakho wezokwelapha, ikakhulukazi noma yiziphi izinkinga zezinso noma izimo ze-autoimmune
• Izithombe zokushintsha kwesikhumba zakho ethathiwe ngokuhamba kwesikhathi ukubonisa intuthuko
• Uhlu lwezimpawu nokuthi zaqala nini
• Imiphumela yamasonto athile uma unayo

Imibuzo ongafuna ukuyibuza ifaka:

• I-calciphylaxis yami isesiphi isigaba futhi lokho kusho ukuthini?
• Ziyini izinketho zokwelapha ezitholakalayo ngesimo sami esithile?
• Sizoyiqapha kanjani intuthuko yami futhi silungise ukwelashwa?
• Ziyini izimpawu engizibona ezingase zibonise izinhlanganisela?
• Ingabe kunemisebenzi engingayigwema ngesikhathi sokuphulukisa?

Unganqikazi ukuletha ilungu lomndeni noma umngani ukukusiza ukukhumbula ulwazi olubalulekile. Ukuba nokusekelwa ngesikhathi se-aphoyintimenti yezokwelapha kungaba usizo ikakhulukazi uma ubhekene nesimo esibuhlungu njenge-calciphylaxis.

Iyini into ebaluleke kakhulu nge-calciphylaxis?

I-Calciphylaxis iyisimo esibuhlungu esidinga ukunakekelwa kwezokwelapha ngokushesha, kodwa ukuxilongwa kwasekuqaleni nokuphathwa okuhle kungathuthukisa kakhulu imiphumela. Okubalulekile ukuqaphela izimpawu ngokushesha nokusebenza eduze neqembu lakho lokunakekelwa kwezokwelapha.

Uma unezinto ezingase zikubangele njengesifo sezinso, qaphela ukushintsha kwesikhumba futhi unganqikazi ukufuna ukunakekelwa kwezokwelapha uma ubona noma yini engavamile. Nakuba i-calciphylaxis ingesaba, intuthuko ekwelapheni iye yathuthukisa ithemba labantu abaningi abanesimo.

Khumbula ukuthi awuwedwa ekuphatheni lesi simo. Iqembu lakho lokunakekelwa kwezokwelapha lilapho ukusekela ngesikhathi sokwelashwa nokuphulukisa, futhi ukulandela isiqondiso sabo kukunika ithuba elihle kakhulu lokuphulukisa nokugcina ikhwalithi yempilo yakho.

Imibuzo evamile ebuzwa nge-calciphylaxis

Q1: Ingabe i-calciphylaxis iyadluliseka?

Cha, i-calciphylaxis ayidluliseki. Awukwazi ukuyithola komunye umuntu noma uyidlulisele kwabanye. Ibangelwa izinkinga zangaphakathi ngokuguqulwa kwe-calcium emzimbeni wakho, hhayi yinoma iyiphi into yokutheleleka njengebhaktheriya noma ama-viruses.

Q2: Ingabe i-calciphylaxis ingapholiswa ngokuphelele?

Nakuba i-calciphylaxis iyisimo esibuhlungu, ingaphathwa ngokuphumelelayo, ikakhulukazi uma itholakala kwasekuqaleni. Abanye abantu bayaphola ngokuphelele ngokwelashwa okufanele, nakuba inqubo ingathatha izinyanga. Okubalulekile ukuqala ukwelashwa ngokushesha nokulandela zonke izeluleko zezokwelapha.

Q3: Ingabe ngizodinga ukusebenza nge-calciphylaxis?

Ukusebenza akuhlale kudingeka nge-calciphylaxis. Abantu abaningi bangaphathwa ngemithi nokukhathalelwa kwamanxeba kuphela. Noma kunjalo, uma uthuthukisa izindawo ezinkulu zethishu efile noma ukutheleleka okukhulu, udokotela wakho angase ancome ukususwa kwethishu ethintekile ukuze athuthukise ukuphulukisa.

Q4: I-calciphylaxis ithatha isikhathi esingakanani ukuphulukisa?

Isikhathi sokuphulukisa sihluka kakhulu kusuka kumuntu komunye futhi siyancika ezintweni njengokuthi ukwelashwa kwaqala nini, impilo yakho yonke, nokuthi uphendula kangcono kangakanani ekwelapheni. Abanye abantu babona intuthuko ngamasonto, kanti abanye bangadinga izinyanga eziningi zokwelashwa ukuze baphole ngokuphelele.

Q5: Ingabe i-calciphylaxis ingabuya ngemuva kokwelashwa?

Yebo, i-calciphylaxis ingabuya, ikakhulukazi uma izimo eziyinhloko ezazibangela zingalawulwa kahle. Kungakho kubalulekile ukuqhubeka nokulawula izinto ezingase zikubangele njengesifo sezinso, ukugcina amazinga afanele e-calcium ne-phosphate, nokugcina ukubonisana okuvamile neqembu lakho lokunakekelwa kwezokwelapha.