Ukuqiniswa Kwe-Adrenal Ezelwe Nayo? Izimpawu, Izimbangela, Nokwelashwa

Ukuqiniswa kwe-adrenal ezelwe nayo (CAH) kuyiqembu leemeko eziwela ezizukulwaneni ezihlasela amagciwane akho e-adrenal. Lezi zinso ezincane zihlala phezulu kwizinkantolo zakho futhi zenze ama-hormone abalulekile umzimba wakho owadingayo ukuze usebenze kahle.

Uma une-CAH, amagciwane akho e-adrenal awanakwenza okwanele kohormone ebizwa ngokuthi i-cortisol. Lokhu kwenzeka ngoba umzimba wakho awunayo noma unayo kancane kakhulu i-enzyme edingekayo ukukhiqiza i-cortisol. Cabanga ngama-enzyme njengabasebenzi abancinyane emzimbeni wakho abasiza ukuba izinguquko zekhemikhali zenzeke ngokulandelana.

Ziyini izimpawu zokuqiniswa kwe-adrenal ezelwe nayo?

Izimpawu ze-CAH zingase zihluke kakhulu kuye ngohlobo olukhona nokuthi lubi kangakanani. Abanye abantu baphawula izimpawu ngokushesha ngemva kokuzalwa, kanti abanye bangase bangabi nazimpawu kuze kube yilapho sebekhulu.

Nazi izimpawu ezivamile ongazibona ezinganeni ezintsha nasezinganeni ezincane:

• I-genitalia engacacile kubantwana abathandekayo (i-genitalia engabonakali ngokucacile njengendoda noma owesifazane)
• I-genitalia enkulu kubantwana abafana
• Ukuphelelwa amanzi okukhulu nokugabha emakhulwini ambalwa okuqala okuphila
• Izinga eliphansi leshukela egazini
• Ukulahlekelwa usawoti okukhulu ngomchamo
• Ukondla okubi nokungaphumeleli ekuzuzeni isisindo
• Ukuvilapha noma ukulala okungavamile

Lezi zimpawu zokuqala zenzeka ngoba umzimba womntanakho ulwa ukuze ugcine ibhalansi efanele yosawoti, ushukela, namafutha ngaphandle kokwanele kwe-cortisol.

Njengoba izingane ezine-CAH zikhula, ungase uqaphele izimpawu ezahlukene ezivela:

• Ukuqala kokuqala kwe-puberty (ngezinye izikhathi eminyakeni engu-2-4 ubudala)
• Ukuqhakazeka okukhulu kokukhula okulandelelwa ubude obufinyeziwe kunokulindelekile
• Ukukhula okukhulu kwezinwele zomzimba
• I-acne enkulu
• Izikhathi ezingavamile noma ezingapheli kubantwana abathandekayo
• Ilizwi elijulile kubantwana abathandekayo
• Ukuthuthukiswa kwemisipha okubonakala kuqhubekile ngokweminyaka yabo

Abanye abantu bane-CAH ephansi engabonakali kuze kube yilapho sebekhulu. Izimpawu zabantu abadala zingafaka izingqinamba zokuzala, izikhathi ezingavamile, ukukhula okukhulu kwezinwele, ne-acne enkulu engaphenduli ekuwelashweni okuvamile.

Ziyini izinhlobo zokuqiniswa kwe-adrenal ezelwe nayo?

Kunezinhlobo ezimbili eziyinhloko ze-CAH, nokuqonda umehluko kungakusiza ukwazi ukuthi yini okulindelekile. Uhlobo olukhona kuya ngokuthi umzimba wakho une-enzyme activity engakanani.

I-CAH Classic iyinhlobo ebuhlungu kakhulu evame ukubonakala ezinganeni ezintsha. Cishe u-75% wabantu abane-CAH Classic banokuthi odokotela babize ngokuthi "ukuphulukisa usawoti," okusho ukuthi imizimba yabo ilahlekelwa usawoti kakhulu futhi ingase ibe nomfutho wamanzi ongokoqobo. Ezinye u-25% zine-CAH Classic "simple virilizing," lapho ukungalingani kwama-hormone kubangela i-puberty yokuqala nezinye izinguquko zokuthuthukiswa kodwa ngokuvamile azibangeli ukulahlekelwa usawoti okusongela impilo.

I-CAH engavamile iphansi kakhulu futhi ngokuvamile ayibangeli izimpawu kuze kube kamuva ebuntwaneni, ebusheni, noma ngisho nasebudaleni. Abantu abalohlobo olukhona ngokuvamile banokusebenza okwanele kwe-enzyme ukuvimbela izinkinga ezinzima ebuntwaneni, kodwa bangase bahlale behlangabezana nokungalingani kwama-hormone njengoba bekhula.

Yini ebangela ukuqiniswa kwe-adrenal ezelwe nayo?

I-CAH ibangelwa yizinguquko (izinguquko) emajini akho ezihlasela indlela amagciwane akho e-adrenal asebenza ngayo. Uzuza lezi zinguquko ze-genetic kubazali bakho, kungakho kubizwa ngokuthi "ezalwe nayo" - okusho ukuthi ikhona kusukela ekuzalweni.

Imbangela evamile ihilela i-gene eyenze i-enzyme ebizwa ngokuthi i-21-hydroxylase. Cishe u-90-95% wabantu abane-CAH banezinguquko kule gene ethile. Ngaphandle kokwanele kwale enzyme, amagciwane akho e-adrenal awanakwenza i-cortisol kahle, kodwa aqhubeka ezama ngokwenza okukhulu kwama-hormone amanye abizwa ngama-androgens.

Ngokungavamile, i-CAH ingabangelwa yizinguquko emajini ezenza ezinye izinhlobo ze-enzyme njenge-11-beta-hydroxylase, i-17-hydroxylase, noma i-3-beta-hydroxysteroid dehydrogenase. Ngamunye walaba ubangela izimpawu ezihlukile kancane, kodwa bonke bahlupha ukukhiqizwa kwama-hormone okuvamile emagciwaneni akho e-adrenal.

I-CAH ilandela lokho ochwepheshe be-genetics abakubiza ngokuthi "i-autosomal recessive" pattern. Lokhu kusho ukuthi udinga ukuzuza i-gene eguqukile kubazali bobabili ukuze ube nale meko. Uma uzuza i-gene eguqukile eyodwa kuphela, "uye umthwali" kodwa ngokuvamile ngeke ube nazimpawu.

Nini okufanele ubheke udokotela ngokuqiniswa kwe-adrenal ezelwe nayo?

Kufanele ufuna ukunakekelwa kwezokwelapha ngokushesha uma uqaphela izimpawu ezithile zezexwayiso, ikakhulukazi ezinganeni ezintsha nasezinganeni ezincane. Lezi zimpawu zingabonisa ingozi enkulu ye-hormone edinga ukwelashwa okusheshayo.

Shaya udokotela wakho ngokushesha uma ubona ukugabha, ukuphelelwa amanzi okukhulu, ukuvilapha okukhulu, noma izimpawu zeswekile eliphansi egazini kumntwana omusha. Lezi zingaba izimpawu zengozi yokulahleka kosawoti, engase ibe yingozi impilo uma ingaphathwa ngokushesha.

Kufanele uxhumane nodokotela wakho uma uqaphela izimpawu zokuqala kwe-puberty ezinganeni ezincane, njengokukhula kwezinwele zomzimba, ukwanda okukhulu kobude, noma izinguquko ze-genitalia ngaphambi kweminyaka engu-8 kubantwana abathandekayo noma iminyaka engu-9 kubafana. Nakuba kungabi yingozi ngokushesha, ukwelashwa okuqala kungasiza ekuvinjeni izinkinga.

Kubantu abadala, cabanga ukubona udokotela uma uhlangabezana nezingqinamba zokuzala ezingachazwanga, izikhathi ezingavamile kakhulu, ukukhula okukhulu kwezinwele ezindaweni ezingavamile, noma i-acne enkulu engathuthuki ngokwelashwa okuvamile. Lezi zingaba izimpawu ze-CAH engavamile eyayingakaqaphelwa ekuqaleni kokuphila.

Ziyini izici ezingozi zokuqiniswa kwe-adrenal ezelwe nayo?

I-risk factor eyinhloko ye-CAH ukuba nabazali abathwala bobabili i-genetic mutation. Njengoba i-CAH iyimeko eyiwela ezizukulwaneni, umlando wakho womndeni udlala indima ebaluleke kakhulu ekuqondeni ingozi yakho.

Amaqembu athile ezizwe anamazinga aphezulu e-CAH. Abantu base-Ashkenazi Jewish, i-Hispanic, i-Slavic, noma i-Italian banesilinganiso esiphezulu sokuthi bangaba ngabathwali bezinguquko ze-genetic eziholela e-CAH. Noma kunjalo, le meko ingase ibe khona kubantu banoma iyiphi indawo.

Uma usuvele unengane enye ene-CAH, kune-25% ithuba lokuthi yonke ingane eyengeziwe nayo ibe nale meko. Lokhu kungenxa yokuthi bobabili abazali bangabathwali, futhi ingane ngayinye inesilinganiso esingu-1-ku-4 sokuzuza i-gene eguqukile kubazali bobabili.

Ukuhlangana kwegazi (ukuba nezingane nomuntu ohlobene nawe ngegazi) futhi kukhuphula ingozi ngoba abantu abahlobene banesilinganiso esiphezulu sokuthi bathwale izinguquko ze-genetic ezifanayo. Noma kunjalo, izingane eziningi ezine-CAH zizalwa kubazali abangahlobene abaye baba ngabathwali.

Ziyini izinkinga ezingase zenzeke ngokuqiniswa kwe-adrenal ezelwe nayo?

Nakuba i-CAH ingaphathwa kahle ngokwelashwa okufanele, kubalulekile ukuqonda izinkinga ezingase zenzeke ukuze ukwazi ukusebenza neqembu lakho lezokwelapha ukuze uzivimbe. Izinkinga eziningi zingagwenywa noma zinciphisiwe ngokuxilongwa okuqala nokuphathwa okuqhubekayo.

Izinkinga ezinkulu zesikhathi esifushane zifaka:

• Ukuhlupheka kwe-adrenal (ukuphelelwa amanzi okukhulu, ukushayisana, nokungalingani kwama-electrolyte)
• Amazinga eswekile egazini aphansi kakhulu
• Ukuphelelwa amanzi okukhulu okungabangela izinkinga zezinso
• Ukwehluleka kokukhula ezinganeni ezingekaphathwa

Lezi zinkinga ezibuhlungu zivame kakhulu kubantu abane-CAH Classic, ikakhulukazi uhlobo olulahlekelwa usawoti, futhi ngokuvamile zenzeka lapho isimo singakaqaphelwa noma ngezikhathi zokucindezeleka noma ukugula.

Izinkinga zesikhathi eside zingathinta ukukhula nokuthuthukiswa:

• Ubude obufinyeziwe bomuntu omdala ngenxa ye-puberty yokuqala nokuhlanganiswa kwangaphambili kwamapuleti okukhula
• Izingqinamba zokuzala kubantu besilisa nabesifazane
• Izikhathi ezingavamile noma ukungabikho kwezikhathi
• Izinselele ezingokwengqondo ezihlobene ne-genitalia engacacile noma ubulili
• Ukungena engozini enkulu ye-osteoporosis ngenxa yokwelashwa isikhathi eside ngama-steroid
• Ukungena engozini enkulu yokukhuluphala nezinselele ze-metabolic

Ngokunakekelwa kwezokwelapha okufanele nokwelashwa kokufaka ama-hormone, abantu abaningi abane-CAH bangaphila impilo enempilo, evamile futhi bagweme lezi zinkinga. Ukuqapha okuqhubekayo nokwenza izinguquko ekwelashweni kusiza ekuqedeni izingozi ngenkathi kugcinwa ikhwalithi enhle yokuphila.

Ukuqiniswa kwe-adrenal ezelwe nayo kungavimbeka kanjani?

Njengoba i-CAH iyimeko ye-genetic, awunakuyivimba uma uzuza ama-gene kubazali bobabili. Noma kunjalo, ukwelulekwa kwe-genetic nokuhlolwa kungakusiza ukuqonda izingozi zakho futhi wenze izinqumo ezinolwazi zokuhlela umndeni.

Uma unomlando womndeni we-CAH noma ungoweqembu lezizwe elinesingozi enkulu, ukwelulekwa kwe-genetic kungakusiza ukuqonda ukuthi ungumthwali yini. Ukuhlolwa komthwali kuhilela ukuhlolwa okulula kwegazi okungabonisa ukuthi unekopi eyodwa ye-gene eguqukile yini.

Uma bobabili abalingani bangabathwali, unezinketho eziningi okufanele uzicabangele. Ukuhlolwa kwangaphambi kokuzalwa ngesikhathi sokukhulelwa kungaxilonga i-CAH embabeni osele ekuthuthukisweni. Abanye abantu bakhetha ukufakwa kwe-in vitro fertilization ngokuhlolwa kwe-genetic kwama-embryo (okubizwa ngokuthi i-preimplantation genetic diagnosis) ukukhetha ama-embryo angenalo le meko.

Emindenini enomlando we-CAH, ukuhlolwa kwangaphambi kwesikhathi kubalulekile. Izwe eziningi manje zifaka i-CAH kuhlelo lwazo oluvamile lokuhlolwa kwangaphambi kwesikhathi, okungabamba le meko ngaphambi kokuba izimpawu zivele futhi kuvumele ukwelashwa ngokushesha.

Ukuqiniswa kwe-adrenal ezelwe nayo kuxilongwa kanjani?

Ukuqaphela i-CAH ngokuvamile kuhilela ukuhlolwa kwegazi okuqapha amazinga ama-hormone, futhi isikhathi salezi zivivinyo siye ngesikhathi izimpawu zivele ngaso. Izimo eziningi manje zibambekile ngohlelo oluvamile lokuhlolwa kwangaphambi kwesikhathi ngaphambi kokuba izimpawu zivele.

Ukuhlolwa kwangaphambi kwesikhathi kuhilela ukuthatha isampula encane yegazi esithendeni somntanakho ezinsukwini ezimbalwa zokuqala zokuphila. Uvivinyo luqapha amazinga wohormone ebizwa ngokuthi i-17-hydroxyprogesterone, evame ukuphakama ezinganeni ezine-CAH.

Uma i-screening test ingavamile, udokotela wakho uzoyala ukuhlolwa kwegazi okuningiliziwe ukuze aqinisekise ukuxilongwa. Lezi zivivinyo zokuqinisekisa ziqapha ama-hormone amaningi kufaka phakathi i-cortisol, i-aldosterone, nama-androgens ahlukahlukene ukuze aqonde ukuthi yiluphi uhlobo lwe-CAH ingane yakho elunalo.

Ezinganeni ezindala nabantu abadala, ukuxilongwa ngokuvamile kuqala lapho izimpawu zivele. Udokotela wakho angase ayale ukuhlolwa kwama-hormone afanayo, ngokuvamile kwenziwa ekuseni lapho amazinga e-cortisol evame ukuphakama khona. Ngezinye izikhathi kudingeka ukuhlolwa kokukhuthaza, lapho uthola khona ukugonywa kwe-ACTH ye-synthetic (uhormone okhuthaza amagciwane e-adrenal) bese uthola igazi lakho lihlolwe ukuze ubone ukuthi izinkantolo zakho ziphendula kanjani.

Ngezinye izikhathi, ukuhlolwa kwe-genetic kungabonisa izinguquko ezithile eziholela e-CAH. Lolu lwazi lungasiza ekuhleleni umndeni nasekuqondeni uhlobo oluqondile lokuntuleka kwe-enzyme olukhona.

Yini ukwelashwa kokuqiniswa kwe-adrenal ezelwe nayo?

Ukwelashwa kwe-CAH kugxile ekuqedeni ama-hormone umzimba wakho ongenakukwenza kahle futhi uphathe izimpawu ekuphileni kwakho konke. Ngokwelashwa okuqhubekayo, abantu abaningi abane-CAH bangaphila impilo evamile, enempilo.

Ukwelashwa okuyinhloko kuhilela ukuthatha imithi ye-corticosteroid ukuze uqede i-cortisol umzimba wakho ongayenzi. Abantu abaningi bathatha i-hydrocortisone, efana ne-cortisol umzimba wakho oyikhiqizayo ngokwemvelo. Uzovame ukuthatha le mithi izikhathi ezimbili kuya kwezintathu ngosuku, ngamanani aphezulu ngezikhathi zokugula noma ukucindezeleka.

Uma unohlobo lwe-CAH olulahlekelwa usawoti, uzodinga futhi imithi ebizwa ngokuthi i-fludrocortisone ukuze usize izinso zakho zigcine usawoti futhi zigcine ibhalansi efanele yamanzi. Abantu abaningi badinga futhi usawoti owengeziwe ekudleni kwabo, ikakhulukazi ngesikhathi sezulu esishisayo noma umsebenzi.

Kubantu abane-genitalia engacacile, ukulungiswa okuyisikhafu kungase kunconywe. Lezi zinqumo ziyinkimbinkimbi futhi kufanele zihilele iqembu lochwepheshe kufaka phakathi ochwepheshe be-endocrinology yabantwana, ochwepheshe be-urology, nochwepheshe bezengqondo. Isikhathi nohlobo lokuhlinzwa kuya ngezimo zomuntu siqu nezifiso zomndeni.

Ukwelashwa ngokuvamile kudinga ukwenziwa izinguquko njengoba ukhula futhi izidingo zomzimba wakho zishintsha. Izingane zingadinga ukwanda kwamanani njengoba zikhula, futhi abesifazane bangadinga ukwenziwa izinguquko ngesikhathi sokukhulelwa. Ukuqapha okuqhubekayo ngokuhlolwa kwegazi kusiza udokotela wakho ukulungisa ukwelashwa kwakho.

Indlela yokuphatha ukuqiniswa kwe-adrenal ezelwe nayo ekhaya?

Ukuphatha i-CAH ekhaya kuhilela ukwakha amasiko amahle ngokwelashwa, ukuphathwa kokucindezeleka, nokukwazi ukuthi nini okufanele ufuna ukunakekelwa kwezokwelapha okwengeziwe. Ngokuthinta okulungile, ungagcina impilo enhle futhi uvikele izinkinga.

Ukuthatha imithi yakho njalo kuyisigaba esibaluleke kakhulu sokuphatha ekhaya. Yenza uhlelo lwansuku zonke olukulokela ukukhumbula amanani akho, njengokuthatha imithi ngesikhathi sokudla noma ukusebenzisa umhleli wemithi. Ungalokothi ushiye amanani noma uyeke ukuthatha imithi yakho ngaphandle kokukhuluma nodokotela wakho kuqala.

Ngesikhathi sokugula, ukulimala, noma ukucindezeleka okukhulu, umzimba wakho udinga i-cortisol eyengeziwe. Udokotela wakho uzokufundisa indlela yokwandisa amanani emithi yakho ngalezi zikhathi. Gcina uhlelo lokusebenza olulotshwe olukuchazela ngokuqondile ukuthi yimalini imithi eyengeziwe okufanele uyithathe nokuthi nini okufanele uxhumane neqembu lakho lezokwelapha.

Hlala uthwala i-medical identification echaza ukuthi une-CAH futhi uhlu lwemithi yakho. Esimweni esiphuthumayo, lolu lwazi lungasindisa impilo. Cabanga ukugqoka i-bracelet yokuxwayisa noma ukugcina ikhadi eliphathekayo esiweni sakho.

Qaphela izimpawu zomzimba wakho futhi ufunde ukuqaphela izimpawu ezingase zibonise ukuthi udinga ukunakekelwa kwezokwelapha. Lezi zifaka ukugabha okuqhubekayo, ukukhathala okukhulu, ukudideka, noma noma iyiphi isimo esibonakala singavamile kuwe.

Kufanele uzilungiselele kanjani i-appointment yakho yodokotela?

Ukulungiselela i-appointment yakho ye-CAH kungakusiza ukuthola okuningi ekuhambeleni kwakho futhi kuqinisekise ukuthi udokotela wakho uneyonke imininingwane edingekayo ukuze anikeze ukunakekelwa okuhle kakhulu. Ukulungiselela okuhle kwenza lezi zivivinyo zibe nomphumela futhi zisebenze kahle.

Gcina idayari yezimpawu phakathi kwama-appointment, ubhale noma iyiphi isimo esingavamile, imiphumela emibi yemithi, noma izikhathi lapho udinga khona ukwandisa amanani akho ngenxa yokugula noma ukucindezeleka. Lolu lwazi lusiza udokotela wakho ukuqonda ukuthi ukwelashwa kwakho kwamanje kusebenza kahle kangakanani.

Letha uhlu oluphelele lwemithi yonke oyithathayo, kufaka phakathi amanani nezikhathi ezifanele. Faka futhi noma iyiphi imithi yokuthengwa ngaphandle komthetho, izithasiselo, noma imithi yemifino, njengoba lezi ngezinye izikhathi zingase zihlangane nemithi yakho ye-CAH.

Bhala phansi noma imiphi imibuzo noma ukukhathazeka okukhonayo ngaphambi kwe-appointment yakho. Izihloko ezivamile zingase zifake ukwenziwa izinguquko zamanani, ukuphatha imiphumela emibi, ukuhlela uhambo noma imicimbi ekhethekile, noma ukukhathazeka ngokukhula nokuthuthukiswa ezinganeni.

Ezinganeni ezine-CAH, letha amashadi okukhula nolwazi lokusebenza esikoleni uma ukhathazekile ngokuthuthukiswa. Udokotela wakho uzothanda ukuqapha kokubili ukukhula komzimba nemigomo yokuqala yokuqala eduze.

Yini eyinhloko ebalulekile ngokuqiniswa kwe-adrenal ezelwe nayo?

Into ebaluleke kakhulu okumele uyiqonde nge-CAH ukuthi nakuba kuyimeko yempilo yonke, ilawuleka kakhulu ngokwelashwa okufanele nokunakekelwa kwezokwelapha. Abantu abaningi abane-CAH bangaphila impilo evamile ngokuphelele lapho bethatha imithi yabo njalo futhi basebenza eduze neqembu labo lezokwelapha.

Ukuqaphela okuqala nokwelashwa kwenza umehluko omkhulu emiphumeleni. Ngenxa yohlelo lokuhlolwa kwangaphambi kwesikhathi, izimo eziningi manje zibambekile ngaphambi kokuba izinkinga ezinzima zivele. Lokhu kuqaphela okuqala kuvumela ukwelashwa ngokushesha futhi kuvimbela izinkinga eziningi ezinzima ezingase zenzeke uma i-CAH ingakaqaphelwa.

Ukuqonda isimo sakho, ukuthatha imithi njengoba kunqunyiwe, nokukwazi ukuthi nini okufanele ufuna ukunakekelwa kwezokwelapha okwengeziwe kuyisihluthulelo sokuphathwa okuphumelelayo. Ngalokhu okuyisisekelo, ungalindela ukuphila impilo enempilo, ehlangabezana nezidingo zakho nakuba une-CAH.

Khumbula ukuthi i-CAH ibathinta bonke ngezindlela ezahlukene, futhi uhlelo lwakho lokwelashwa kufanele lulungiswe ngezidingo zakho ezithile. Ukuxhumana okuqhubekayo neqembu lakho lezokwelapha kuqinisekisa ukuthi ukwelashwa kwakho kuhlala kuphelele njengoba izidingo zomzimba wakho zishintsha ngokuhamba kwesikhathi.

Imibuzo evamile ebuzwa ngokuqiniswa kwe-adrenal ezelwe nayo

Abantu abane-CAH bangaba nezingane yini?

Yebo, abantu abaningi abane-CAH bangaba nezingane, nakuba ukukhulelwa kungase kuthonye ezinye izimo. Abesifazane abane-CAH bangase babe nezikhathi ezingavamile noma badinge ukwelashwa ukuthuthukisa ukukhulelwa. Amadoda ane-CAH ngokuvamile anamahloni okuzala okuvamile. Ukusebenza nochwepheshe we-endocrinology yokuzala kungasiza uma unengcindezi yokukhulelwa.

Imithi ye-CAH ibangela ukukhuluphala yini?

Abanye abantu baye bahlangabezana nokukhuluphala ngokwelashwa kwe-corticosteroid, kodwa lokhu akuyona into engaqondakali. Isihloko ukufumana inani elifanele eliqeda lokho umzimba wakho olukudingayo ngaphandle kokukunika okuningi. Ukwenza umsebenzi njalo, ukudla okunempilo, nokusebenza nodokotela wakho ukulungisa amanani akho kungasiza ekulawuleni ukukhathazeka ngesisindo.

Imithi ye-CAH ingayeka yini uma izimpawu zithuthuka?

Cha, imithi ye-CAH akufanele iyeke ngisho noma uzizwa kahle. Le mithi iyayiqeda ama-hormone umzimba wakho ongenakukwenza, ngakho ukuyayeka kungabangela izinkinga ezinzima kufaka phakathi ingozi ye-adrenal. Hlala ukhuluma nodokotela wakho ngaphambi kokwenza noma iyiphi inguquko kuhlelo lwakho lwemithi.

Ukucindezeleka kuthinta kanjani i-CAH?

Ukucindezeleka komzimba nokwengqondo kukhuphula isidingo somzimba wakho se-cortisol. Njengoba abantu abane-CAH bengenakwenza i-cortisol eyengeziwe ngokwemvelo, ungase udinga ukwandisa amanani emithi yakho okwesikhashana ngezikhathi zokucindezeleka njengokugula, ukuhlinzwa, noma izehlakalo ezinkulu zokuphila. Udokotela wakho uzokufundisa indlela yokulungisa amanani akho ngokufanele.

I-CAH ivame kakhulu emindenini ethile noma emaqenjini ezizwe?

Yebo, i-CAH ivame kakhulu kubantu abathile kufaka phakathi abantu base-Ashkenazi Jewish, i-Hispanic, i-Slavic, ne-Italian. Noma kunjalo, ingase ibe khona kunoma iyiphi indawo. Uma unomlando womndeni we-CAH noma ungoweqembu elinesingozi enkulu, ukwelulekwa kwe-genetic kungakusiza ukuqonda izingozi zakho nezinketho zakho.