Iyini i-Factor V Leiden? Izimpawu, Izimbangela, kanye Nokwelashwa

I-Factor V Leiden yisimo sezofuzo esenza igazi lakho liqine kalula kunokujwayelekile. Yisifo esivamile kakhulu sezofuzo sokuqina kwegazi, esithinta abantu abacishe babe ngu-5% abanesizwe saseYurophu.

Lesi simo sivela lapho uzuza ushintsho oluthile lwe-jini oluthinta indlela igazi lakho elivikela ngayo ngokwemvelo ukuba lingaqini. Nakuba abantu abaningi abane-Factor V Leiden abazange babe nezinkinga, abanye bangathuthukisa ukuqina kwegazi okungaba nzima uma kungelashwa.

Iyini i-Factor V Leiden?

I-Factor V Leiden yishintsho lezofuzo elithinta iprotheni ebizwa nge-Factor V ohlelweni lwakho lokuqina kwegazi. Le protheni ngokuvamile iyasiza igazi lakho liqine uma ulimazile, bese ivaliwe yiprotheni enye ebizwa nge-activated protein C.

Uma une-Factor V Leiden, iprotheni eguqukile imele ukuba ivaliwe yi-activated protein C. Cabanga ngayo njengokuswitsha okuqina okuhlala ku- "on" position. Lokhu kwenza igazi lakho libe nethuba elikhulu lokuqina ngisho noma awudingi.

Uzuza lesi simo kubazali bakho nge-jini zakho. Ungazuza ikhophi eyodwa yoshintsho lwe-jini noma izikhophi ezimbili, okuthinta ukuthi unethuba elingakanani lokuthuthukisa ukuqina kwegazi.

Ziyini izimpawu ze-Factor V Leiden?

I-Factor V Leiden ngokwayo ayibangeli zimpawu. Abantu abaningi abanesimo sezofuzo abazizwa beqondile futhi bangase bangazi ukuthi banaso ngaphandle kokuthi bathuthukise ukuqina kwegazi noma bahlolwe ngezizathu ezingezona.

Izimpawu ongazihlangabezana nazo zivela ekuqineni kwegazi okungase kube khona ngenxa ye-Factor V Leiden. Nazi izimpawu ezibonisa ukuthi ukuqina kwegazi kungase kube khona:

Izimpawu ze-deep vein thrombosis (DVT) zihlanganisa:

• Ukuvuvukala kwelinye uhlangothi, ngokuvamile i-calf noma i-thigh
• Ubuhlungu noma ubuhlungu ohlangothini oluthintekile
• Ubushushu endaweni evuvukile
• Isikhumba esibomvu noma esishintshile ehlangothini
• Ukuqina kwezinyawo okungapheli

Izimpawu ze-pulmonary embolism zihlanganisa:

• Ukuphefumula okusheshayo ngokuzumayo
• Ubuhlungu obukhulu besifuba obukhulu lapho uphefumula
• Izinga lenhliziyo eliphakeme
• Ukuhlanza igazi
• Ukuzizwa ukhuluphuka noma ukhanya

Lezi zimpawu zidinga ukunakekelwa kwezokwelapha ngokushesha ngoba ukuqina kwegazi kungaba yingozi uma kuya emaphashini noma kwamanye amalungu omzimba abalulekile.

Yini ebangela i-Factor V Leiden?

I-Factor V Leiden ibangelwa yishintsho elithile lezofuzo olizuza kubazali bakho. Lesi shintsho lithinta i-jini ezenza i-Factor V protein, edlala indima ebalulekile enkambeni yakho yokuqina kwegazi.

Ishintsho livela lapho i-building block eyodwa ye-DNA ishintsha ku-Factor V gene. Lesi shintsho esincane senza i-Factor V protein imele ukuba iphulwe yi-activated protein C, evame ukusisiza ukuvimbela ukuqina okukhulu.

Ungazuza lesi simo ngezindlela ezimbili. Uma omunye umzali ephila ngalesi shintsho, ungazuza ikhophi eyodwa ye-gene eguqukile. Uma bobabili abazali bephila ngayo, ungazuza izikhophi ezimbili, okwandisa ingozi yakho yokuqina kwegazi.

Lesi shintsho lezofuzo cishe senzeke eminyakeni eyizinkulungwane edlule futhi kungenzeka ukuthi sinikeze inzuzo ethile yokusinda kubakhokho bethu, mhlawumbe ngokunciphisa ukuphuma kwegazi ngesikhathi sokubeletha noma ekulimaleni.

Nini okufanele ubona udokotela nge-Factor V Leiden?

Kufanele ubona udokotela ngokushesha uma uhlangabezana nanoma yiziphi izimpawu zokuqina kwegazi, njengokuvuvukala okungazelelwe kwezinyawo, ubuhlungu besifuba, noma ukuphefumula okunzima. Lezi zimpawu zidinga ukuhlolwa kwezokwelapha okusheshayo kungakhathaliseki ukuthi uyazi ukuthi une-Factor V Leiden noma cha.

Cabanga ngokuxoxa ngokuvivinywa kwe-Factor V Leiden nodokotela wakho uma unemlando womndeni wokuqina kwegazi, ikakhulukazi uma izihlobo zithuthukise ukuqina kwegazi ebuntwaneni noma ngaphandle kwezinye izimbangela ezicacile njengokuhlinzwa noma izikhathi ezinde zokungabi namandla.

Kufanele uxoxe nodokotela wakho ngokuvivinywa uma uhlela ukukhulelwa, ucabanga ngokwelashwa kwe-hormone, noma ukulungiselela ukuhlinzwa okukhulu. Lezi zimo zingakwandisa ingozi yokuqina kwegazi uma une-Factor V Leiden.

Uma usuvele ube nokuqina kwegazi okungachazeki, udokotela wakho cishe uzofuna ukukuhlola ngezifo ezihlukahlukene zokuqina kwegazi, kufaka phakathi i-Factor V Leiden, ukuqonda ingozi yakho nokuhlela ukwelashwa okufanele.

Ziyini izimbangela zengozi ze-Factor V Leiden?

Imbangela eyinhloko yengozi yokuba ne-Factor V Leiden yizofuzo. Unethuba elikhulu lokuba nalesi simo uma unesizwe saseYurophu, ikakhulukazi uma imvelaphi yomndeni wakho ihlanganisa i-Northern European, i-Mediterranean, noma i-Middle Eastern heritage.

Izici eziningi zingakwandisa ingozi yakho yokuqina kwegazi uma une-Factor V Leiden:

Izimbangela zengozi zesikhashana zihlanganisa:

• Ukukhulelwa neviki eziyisithupha zokuqala ngemuva kokubeletha
• Ukuthatha amaphilisi okuvimbela ukukhulelwa noma ukwelashwa kwe-hormone replacement
• Ukuhlinzwa, ikakhulukazi izinqubo ze-orthopedic noma ze-abdominal
• Ukungabi namandla isikhathi eside, njengasesikhathini sokuhamba noma sokulala embhedeni
• Ukuba nezimo ezithile zezokwelapha njengomdlavuza noma izifo ezivuvukalayo

Izimbangela zengozi eziqhubekayo zihlanganisa:

• Ukuba ngaphezu kweminyaka engama-60
• Ukuba nobude
• Ukubhema iziqhumane
• Ukuba nezinye izifo zokuqina kwegazi ezizuzwe
• Ukuba nomlando wokuqina kwegazi ngaphambili

Izimbangela zengozi eziningi onazo ezihlangene ne-Factor V Leiden, amathuba akho okuba nokuqina kwegazi aphakeme. Udokotela wakho angakusiza uqonde amazinga akho engozi.

Ziyini izinhlanganisela ezingase zenzeke ze-Factor V Leiden?

Inhlanganisela eyinhloko ye-Factor V Leiden ukuqina kwegazi, okungaba ukusuka kokungakhululeki kuya kokubulala ngokuxhomekeke ekutheni kuqina kuphi nokuthi kuphathwa kanjani.

Nazi izinhlanganisela ezivamile ongazihlangabezana nazo:

I-Deep vein thrombosis (DVT) yinhlelo ehlala ivela. Lezi ziqina ngokuvamile ziqina ezinhlangothini eziqinele zezinyawo zakho futhi zingabangela ubuhlungu, ukuvuvukala, nokulimala okungapheli kwezinhlangothi zakho uma zingaphathwa ngokushesha.

I-Pulmonary embolism kwenzeka lapho ukuqina kwegazi kuhamba ukusuka ezinyawo zakho kuya emaphashini akho. Lena yinhlelo enzima, engase ibe yingozi edinga ukwelashwa okusheshayo kwezokwelapha.

Izinhlanganisela zokukhulelwa zingase zihlanganise ingozi ephakeme yokuphulukana nokukhulelwa, ikakhulukazi ezikhathini zesibili nesithathu, kanye nezinhlanganisela njenge-preeclampsia noma izinkinga ze-placenta.

Izinhlanganisela ezingavamile zingase zihlanganise ukuqina kwegazi ezindaweni ezingavamile, njengezinhlangothi esiswini sakho, ebuchosheni, noma kwamanye amalungu omzimba. Lezi azivamile kodwa zingaba nzima uma zenzeka.

Izindaba ezinhle ukuthi abantu abaningi abane-Factor V Leiden abazange babe naziphi na izinhlanganisela, nalabo abenza kanjalo ngokuvamile bangabaphatha ngokuphumelelayo ngokunakekelwa kwezokwelapha okufanele.

I-Factor V Leiden ingavikeleka kanjani?

Awukwazi ukuvimbela i-Factor V Leiden ngokwayo ngoba yisimo sezofuzo ozalwa naso. Noma kunjalo, unganciphisa kakhulu ingozi yakho yokuqina kwegazi ngokwenza izinqumo ezihlakaniphile zokuphila nokuhlanganyela neqembu lakho lezokunakekelwa kwezempilo.

Nazi izinyathelo ezisebenzayo ongazithatha ukuze unciphise ingozi yakho yokuqina:

Hlala usebenza ngokomzimba ngokuzivocavoca njalo nokuqeda izikhathi ezinde zokuhlala noma ulele. Ngisho nemisebenzi elula njengokuhamba noma ukuqina izingalo zakho ngesikhathi sokuhamba okungamade okungasiza ukugcina igazi lakho ligeleza.

Gcina isisindo esinempilo ngoba isisindo esiningi sikwandisa ingozi yokuqina kwegazi. Ukudla okulinganiselayo nokuzivocavoca njalo kungakusiza ufinyelele futhi ugcine isisindo esinempilo.

Ungabhemi noma uyeke uma ubhema njengamanje. Ukubhema kukwandisa kakhulu ingozi yokuqina kwegazi, ikakhulukazi uma kuhlangene ne-Factor V Leiden.

Xoxa ngokusetshenziswa kwe-hormone ngokucophelela nodokotela wakho. Amaphilisi okuvimbela ukukhulelwa ne-hormone replacement therapy angakwandisa ingozi yokuqina, ngakho-ke kuzodingeka uqonde izinzuzo nezingozi nodokotela wakho.

Ngesikhathi sezimo ezingozi eziphakeme njengokuhlinzwa, ukukhulelwa, noma izikhathi ezinde zokungabi namandla, udokotela wakho angase akukhuthaze izinyathelo ezengeziwe zokuvimbela njenge-compression stockings noma imithi yokunciphisa igazi.

I-Factor V Leiden ihlonishwa kanjani?

I-Factor V Leiden ihlonishwa ngokuhlolwa kwegazi okubuka ushintsho lezofuzo noma ukulinganisa indlela igazi lakho eliphendula ngayo ku-activated protein C. Udokotela wakho ngokuvamile uzo-oda lezi zihloko uma unezimbangela zengozi noma usuvele uthuthukise ukuqina kwegazi.

Ivivinyo eliqinisekile kakhulu ukuhlolwa kwezofuzo okubuka ngqo ushintsho lwe-Factor V Leiden ku-DNA yakho. Leli vivinyo lingakutshela ukuthi unekhophi eyodwa noma ezimbili zoshintsho, okuthinta amazinga akho engozi.

Elinye ivivivinyo elibizwa nge-activated protein C resistance test lilinganisa ukuthi igazi lakho liphendula kangcono kanjani ku-activated protein C. Uma igazi lakho lingaphenduli ngokujwayelekile, kubonisa ukuthi ungase ube ne-Factor V Leiden noma enye into ebangela ukuqina kwegazi.

Udokotela wakho angase futhi a-ode ukuhlolwa kwegazi okwengeziwe ukubuka ezinye izifo zokuqina kwegazi ezizuzwe, njengoba abantu ngezinye izikhathi babe nezimo eziningi ezandisa ingozi yokuqina kwegazi.

Ukuphathwa kwe-Factor V Leiden kuyini?

Ukuphathwa kwe-Factor V Leiden kugxile ekuvimbeleni ukuqina kwegazi kunokwelapha isimo sezofuzo ngokwaso. Abantu abaningi abane-Factor V Leiden abadingi ukwelashwa ngaphandle kokuthi bathuthukise ukuqina kwegazi noma babe nezimbangela zengozi eziphakeme kakhulu.

Uma uthuthukisa ukuqina kwegazi, udokotela wakho uzokunikeza imithi ye-anticoagulant, evame ukubizwa ngokuthi yi-blood thinners. Le mi thi ayiqinisi igazi lakho kepha iyasiza ukuvimbela ukuqina okusha ukuba kuqale nokuqina okukhona ukuba kukhulu.

Imithi evamile yokunciphisa igazi ihlanganisa:

• I-Warfarin, edinga ukuqapha igazi njalo
• I-Direct oral anticoagulants njenge-rivaroxaban, i-apixaban, noma i-dabigatran
• I-Heparin injections yokwelashwa okusheshayo noma lapho amaphilisi engafaneleki

Ubude bokuwelashwa kuncike ezintweni eziningi, kufaka phakathi ukuthi lokhu kwakuyikho ukuqina kwakho kokuqala, yini eyakubangela, kanye nengozi yakho yonke yokuthuthukisa ukuqina kwesikhathi esizayo. Abanye abantu badinga ukwelashwa okwesikhashana, ngenkathi abanye bangadinga i-anticoagulation yempilo yonke.

Udokotela wakho angase futhi akukhuthaze ukwelashwa okuvimbelayo ngesikhathi sezimo ezingozi eziphakeme, njengaphambi kokuhlinzwa noma ngesikhathi sokukhulelwa, ngisho noma awukaze ube nokuqina ngaphambili.

Indlela yokuphatha i-Factor V Leiden ekhaya?

Ukuphatha i-Factor V Leiden ekhaya kuhilela ukwenza izinqumo zokuphila ezinciphisa ingozi yakho yokuqina kwegazi ngenkathi ugcina impilo yakho yonke kanye nekhwalithi yempilo.

Hlala usebenza futhi uhambe usuku lonke. Thatha ama-break njalo ekuhlaleni, ikakhulukazi ngesikhathi sokuhamba ngemoto noma ngezindiza. Ukuzivocavoca okulula njengokuqina izingalo noma ukujikeleza izinzwane kungasiza ukugcina igazi lakho ligeleza.

Gqoka i-compression stockings uma udokotela wakho ekukhuthaza, ikakhulukazi ngesikhathi sokuhamba noma izikhathi lapho ungabi namandla. Lezi stocking ezikhethekile zisiza ukuthuthukisa ukugeleza kwegazi ezinyawo zakho.

Hlala uthola amanzi anele, ikakhulukazi ngesikhathi sokuhamba noma isimo sezulu esishisayo. Ukungabi namanzi kungenza igazi lakho libe qinile futhi kukhulise ingozi yokuqina.

Yazi izimpawu zokuqina kwegazi futhi ufuna ukunakekelwa kwezokwelapha ngokushesha uma uhlangabezana nezimpawu njengokuvuvukala okungazelelwe kwezinyawo, ubuhlungu besifuba, noma ukuphefumula okunzima.

Uma uthatha imithi yokunciphisa igazi, landela imiyalo yodokotela wakho ngokucophelela mayelana nokuthola imithi nokuqapha. Gcina uhlu lwemithi yakho futhi uqondise bonke abahlinzeki bezempilo ngokuqonda kwakho i-Factor V Leiden.

Kufanele ulungiselele kanjani i-aphoyintimenti yakho yodokotela?

Ukulungiselela i-aphoyintimenti yakho kuzokusiza uthole okuningi esikhathini sakho nodokotela wakho futhi kuqinisekise ukuthi uthola ukunakekelwa okungcono kakhulu kwe-Factor V Leiden yakho.

Butha umlando wakho wezokwelapha womndeni, ikakhulukazi ulwazi mayelana nokuqina kwegazi, izifo zokuqina kwegazi, noma ukuhlaselwa kwenhliziyo ezihlotsheni zakho. Qaphela iminyaka lapho lezi zenzakalo zenzeka khona nanoma yiziphi izimbangela ezaziwayo.

Bala yonke imithi yakho yamanje, kufaka phakathi imithi yokwelapha, imithi ye-over-the-counter, kanye nezinye izinto. Ezinye imithi ingathinta ingozi yakho yokuqina noma ihlangane ne-blood thinners.

Bhala izimpawu zakho uma uhlangabezana nanoma yiziphi, kufaka phakathi ukuthi zaqala nini, yini ezenza zibe ngcono noma zimbi, nokuthi zikuthinta kanjani imisebenzi yakho yansuku zonke.

Lungiselela imibuzo yakho kusengaphambili. Cabanga ngokubuza ngezinga lakho lengozi, ukuthi udinga ukwelashwa yini, ukuguqulwa kokuphila okufanele ukwenze, nokuthi kufanele ufuna ukunakekelwa okusheshayo nini.

Letha ilungu lomndeni noma umngani uma ufuna ukusekelwa, ikakhulukazi uma uxoxa ngezinketho zokwelashwa eziyinkimbinkimbi noma uma uzizwa ukhathazekile ngokuqonda kwakho.

Yini eyinhloko mayelana ne-Factor V Leiden?

I-Factor V Leiden yisimo sezofuzo esivamile esikhuphula ingozi yakho yokuqina kwegazi, kodwa ilawuleka ngendlela efanele kanye nokunakekelwa kwezokwelapha. Abantu abaningi abanesimo baphila impilo evamile, enempilo.

Into ebaluleke kakhulu okumele uyikhumbule ukuthi ukuba ne-Factor V Leiden akusho ukuthi uzoba nokuqina kwegazi. Ingozi yakho yangempela incike ezintweni eziningi, kufaka phakathi indlela yakho yokuphila, ezinye izimo zezempilo, nezimo ezikhethekile zokuphila.

Ukuhlanganyela eduze neqembu lakho lezokunakekelwa kwezempilo, ukuhlala unolwazi ngesimo sakho, nokuthatha izinqumo ezihlakaniphile zokuphila kunganciphisa kakhulu ingozi yezinhlanganisela. Ungavumeli i-Factor V Leiden ibeke umkhawulo ekuphileni kwakho, kodwa yithathe ngokungathi sína ngokwanele ukwenza izinqumo ezilwemi mayelana nempilo yakho.

Khumbula ukuthi ucwaningo lwezokwelapha luyaqhubeka luthuthukisa ukuqonda kwethu i-Factor V Leiden nokuthuthukisa ukwelashwa okungcono. Hlala uxhumene nodokotela wakho ukuze uthole isiqondiso samanje kakhulu mayelana nokuphatha isimo sakho.

Imibuzo evamile ebuzwa mayelana ne-Factor V Leiden

Ngingayidlulisela yini i-Factor V Leiden kubantwana bami?

Yebo, i-Factor V Leiden yisimo sezofuzo esizuzwayo ongayidlulisela kubantwana bakho. Umuntu ngamunye unethuba elingu-50% lokuzuza isimo uma omunye umzali enaso. Uma bobabili abazali bene-Factor V Leiden, amathuba aphakeme, futhi abantwana bangazuza izikhophi ezimbili zoshintsho, okwandisa ingozi yabo yokuqina kakhulu. Ukukhanselwa kwezofuzo kungakusiza uqonde izingozi ezikhethekile zomndeni wakho.

Kuphephile yini ukuthatha amaphilisi okuvimbela ukukhulelwa uma ngine-Factor V Leiden?

Amaphilisi okuvimbela ukukhulelwa angakwandisa ingozi yokuqina kwegazi, futhi le ngozi iphakeme uma une-Factor V Leiden. Noma kunjalo, isinqumo asiyona "cha" ngokuzenzakalelayo - kuncike ezintweni zakho zengozi, umlando womndeni, nokuthi usuvele ube nokuqina ngaphambili. Udokotela wakho uzolulinganisa izinzuzo nezingozi ngokucophelela futhi angase akukhuthaze ezinye izindlela zokuvimbela ukukhulelwa noma ukuqapha okuqinile uma ukhetha ukwelashwa kwe-hormonal contraception.

Ngabe ngizodinga ukuthatha i-blood thinners ukuphila kwami konke?

Akunjalo ngokuqinisekile. Abantu abaningi abane-Factor V Leiden abadingi i-blood thinners nhlobo. Uma uthuthukisa ukuqina kwegazi, ubude bokuwelashwa kuncike ezintweni eziningi, kufaka phakathi ukuthi yini eyakubangela ukuqina, ukuthi kuyikho kokuqala, kanye nengozi yakho yonke yokuqina kwesikhathi esizayo. Abanye abantu badinga ukwelashwa izinyanga ezimbalwa nje, ngenkathi abanye bangadinga ukwelashwa isikhathi eside. Udokotela wakho uzohlola njalo isidingo sakho sokuqhubeka nokwelashwa.

Ngingazivocavoca ngokujwayelekile nge-Factor V Leiden?

Yebo, ukuzivocavoca njalo kuwusizo futhi kunconywa kubantu abane-Factor V Leiden. Ukuzivocavoca kusiza ukuthuthukisa ukugeleza kwegazi futhi kunganciphisa ingozi yakho yokuqina kwegazi. Awudingi ukuqeda noma yiziphi izinhlobo zokuzivocavoca ngaphandle uma uthatha imithi yokunciphisa igazi, lapho udokotela wakho angase akukhuthaze ukuqeda imidlalo yokuxhumana engase ibe nokulimala okuphuma igazi.

Kufanele ngenzeni uma ngihlela ukuhlinzwa?

Qondise iqembu lakho lokuhlinzwa ngokuqonda kwakho i-Factor V Leiden ngaphambi kwenqubo yakho. Ukuhlinzwa kukhuphula ingozi yokuqina kwegazi kubo bonke, futhi le ngozi iphakeme uma une-Factor V Leiden. Odokotela bakho bangase bakukhuthaze izinyathelo zokuvimbela njengemi thi yokunciphisa igazi, i-compression stockings, noma ukuhamba ngokushesha ngemuva kokuhlinzwa. Indlela ethile izoncika ohlotsheni lokuhlinzwa kanye nezinto zakho zengozi. Ungalokothi ushiye le ngxoxo - kubalulekile ekuphileni kwakho.