Ukuthi yini i-Gilbert's Syndrome? Izimpawu, Izimbangela, & Ukwelashwa

I-Gilbert's syndrome iyimo elithambile, elidluliselwa ngezofu, elienza isibindi sakho sikhiphe i-bilirubin ngendlela ehlukile kunokujwayelekile. Lokhu kuhlukahluka kwe-genetic okungenangozi kuchaphazela indlela umzimba wakho uqhekeza ngayo amangqamuzana egazi amadala, ngezinye izikhathi kuholela emazingeni aphezulu kancane e-bilirubin egazini lakho.

Abantu abaningi abane-Gilbert's syndrome baphila impilo evamile ngokuphelele ngaphandle kwanoma yiziphi izimpawu. Uma izimpawu zivele, zivame ukuba zithambile futhi zingekho isikhathi eside, ngokuvamile zibangelwa ukucindezeleka, ukugula, noma ukweqa ukudla.

Iyini i-Gilbert's syndrome?

I-Gilbert's syndrome iyimo elingenangozi lesibindi lapho umzimba wakho ukhulula khona inani elincane lensimbi ebizwa nge-UDP-glucuronosyltransferase. Le nsimbi iyasiza isibindi sakho ukuba sikhiphe i-bilirubin, into emhlophe eyenziwa lapho umzimba wakho uqhekeza amangqamuzana egazi amadala.

Cabanga ngakho njengokuba nesimiso sokuqhekeza esinciphile kancane esibindini sakho. I-bilirubin isaqhekezwa, kodwa ayikho ngokushesha njengabantu abangenayo leli mo. Lokhu kungaholela emazingeni e-bilirubin ukuba akheke okwesikhashana egazini lakho.

Leli mo lichaphazela cishe u-3-12% wabantu, okwenza libe livamile. Abantu abaningi bane-Gilbert's syndrome ngaphandle kokwazi, njengoba ngokuvamile lingabangeli zinkinga ezibonakalayo.

Ziyini izimpawu ze-Gilbert's syndrome?

Abantu abaningi abane-Gilbert's syndrome abanawo noma yimiphi impawu. Uma izimpawu zivele, zivame ukuba zithambile futhi ziye zihambe ngokungalindelekile.

Nawa amanye amaphuzu avamile ongawaqaphela:

• Ukuphenduka kombala olukhanyayo lwesibuko nesikhumba (jaundice)
• Ukuzizwa ukhathele noma ubuthakathaka
• Ubuhlungu obuthambile besisu
• Ukwehluleka kokudla
• Ukuzizwa ungaphili kahle

Lezi zimpawu ngokuvamile zivele ngezikhathi zokucindezeleka, ukugula, ukuzivocavoca okukhulu, noma uma ungadlanga isikhathi eside. Ukuphenduka kombala olukhanyayo kuvame ukuba buthambile futhi kungabonakala kuphela ekukhanyeni okukhulu.

Yini ebangela i-Gilbert's syndrome?

I-Gilbert's syndrome ibangelwa ukuguquka kwe-UGT1A1 gene, oyithola kubazali bakho. Lokhu kuhlukahluka kwe-genetic kunciphisa inani lensimbi isibindi sakho esiyikhiqizayo ukuze sikhiphe i-bilirubin.

Udinga ukudlulisela i-gene eguqukile kubazali bobabili ukuze uthole i-Gilbert's syndrome. Uma uyithola kuphela komunye umzali, uzobe ungumthwali kodwa ngeke ube naleli mo.

Lokhu akuyona into ongayithola kwabanye noma uyithole kamuva ekuphileni kwakho. Uzokuzalwa nawo, nakuba izimpawu zingase zingabonakali kuze kube ngeminyaka yakho yobusha noma ekuqaleni kokukhula kwakho lapho ukuguquka kwamahomoni kungabangela izimpawu zokuqala ezibonakalayo.

Nini okufanele ubone udokotela nge-Gilbert's syndrome?

Kufanele uxhumane nodokotela wakho uma uqaphela ukuphenduka kombala olukhanyayo lwesibuko noma isikhumba, ikakhulukazi uma kuhambisana nezinye izimpawu. Nakuba i-Gilbert's syndrome ingenangozi, i-jaundice ngezinye izikhathi ingabonisa izimo ezinzima zesibindi ezidinga ukunakekelwa kwezokwelapha.

Funani ukunakekelwa kwezokwelapha uma uhlangabezana nalokhu:

• Ukuphenduka kombala olukhanyayo lwesibuko noma isikhumba ngokuzumayo noma okukhulu
• Umyisa omnyama noma izinsalela ezimhlophe
• Ubuhlungu besisu obukhulu
• Ukuqina kokukhathala noma ubuthakathaka
• Ukuqina komkhuhlane kanye ne-jaundice

Udokotela wakho angenza izivivinyo zegazi ezilula ukuze aqinisekise ukuthi izimpawu zakho zihambisana ne-Gilbert's syndrome noma into enye edinga ukwelashwa.

Ziyini izimbangela zengozi ze-Gilbert's syndrome?

Njengoba i-Gilbert's syndrome iyimo elidluliselwa ngezofu, imbangela yakho enkulu yingozi ukuba nabazali abaphethe ukuguquka kwe-genetic. Leli mo livame kakhulu kubantu abathile futhi lichaphazela amadoda kakhulu kunabesifazane.

Izici eziningi zingabangela izimpawu kubantu abaneli mo:

• Ukweqa ukudla noma ukuzila ukudla
• Ukucindezeleka komzimba noma kwengqondo
• Ukuhlupheka noma ukutheleleka
• Ukuzivocavoca okukhulu
• Ukuphelelwa amanzi emzimbeni
• Imithi ethile
• Ukuguquka kwamahomoni

Ukuqonda lezi zici zingakusiza ukuba uphathe leli mo kangcono futhi ugweme ukukhathazeka okungadingeki uma izimpawu zivele.

Ziyini izinhlanganisela ezingaba khona ze-Gilbert's syndrome?

I-Gilbert's syndrome ayivamile ukubangela noma yiziphi izinhlanganisela ezinzima. Leli mo lithathelwa ingqondo njengelingenangozi, okusho ukuthi alilimazi isibindi sakho noma alichaphazeli impilo yakho yonke ngezindlela ezinkulu.

Kodwa-ke, kunezinto ezimbalwa okufanele uzazi:

• Ukuncipha kokuzinzisa kwemithi ethile ehlanzwa yisibindi
• Amathuba okuqondwa kabi uma odokotela bangaqondi leli mo
• Ukukhathazeka ngezimpawu eziphindaphindayo
• Izimo ezingavamile zokwakheka kwamagatsha ngenxa yokwanda kwe-bilirubin

Into ebaluleke kakhulu okumele uyikhumbule ukuthi i-Gilbert's syndrome ayithuthuki ibe yisifo esinzima sesibindi. Ukusebenza kwesibindi sakho kuhlala kujwayelekile, futhi leli mo alichaphazeli isikhathi sakho sokuphila.

I-Gilbert's syndrome ihlonishwa kanjani?

Odokotela ngokuvamile bahlonishwa i-Gilbert's syndrome ngokusebenzisa izivivinyo zegazi ezilinganisa amazinga e-bilirubin. Ukutholakala okubalulekile yi-bilirubin engatholwanga ehlanganisiwe ngenkathi ezinye izivivinyo zokusebenza kwesibindi zihlala zijwayelekile.

Udokotela wakho angase ayalele izivivinyo eziningi ukuze aqinisekise ukuxilongwa:

• Ukuhlanganiswa kwegazi okuphelele ukuze ahlole i-anemia
• Izivivinyo zokusebenza kwesibindi
• Amazinga e-bilirubin (womabili wonke kanye neqondile)
• Ukuhlolwa kwe-genetic kwezinye izimo

Ngezinye izikhathi odokotela basebenzisa isivivinyo sokuzila ukudla, lapho udle khona ukudla okuncane kakhulu kwamazuba ambalwa. Kubantu abane-Gilbert's syndrome, lokhu ngokuvamile kubangela amazinga e-bilirubin ukuba aphakame nakakhulu, okusiza ekuqinisekiseni ukuxilongwa.

Ukuphathwa kwe-Gilbert's syndrome kuyini?

I-Gilbert's syndrome ayidingi noma yiluphi ukwelashwa kwezokwelapha oluqondile ngoba iyimo elingenangozi elingalilimazi isibindi. Ukugxila okuyinhloko kukuphatheni izimpawu uma zivele nokuqonda izici zakho.

Umhlinzeki wakho wezokunakekelwa kwezempilo angase akukhuthaze:

• Ukugwema izici ezaziwayo njengokuzihlukanisa noma ukucindezeleka okukhulu
• Ukugcina izindlela zokudla eziqondile
• Ukuhlala unamanzi ngokwanele
• Ukuphumula ngokwanele
• Ukuphatha ukucindezeleka ngezindlela zokupumula

Kwezinye izimo lapho izimpawu zikhathaza khona, udokotela wakho angase anikeze imithi ebizwa nge-phenobarbital, engasiza ekuthambiseni amazinga e-bilirubin. Kodwa-ke, lokhu akudingeki.

Ungayiphatha kanjani i-Gilbert's syndrome ekhaya?

Ukuphatha i-Gilbert's syndrome ekhaya kugxile ekukhetheni indlela yokuphila esiza ekunciphiseni izimpawu. Izindaba ezinhle ukuthi imikhuba yansuku zonke elula ingenza umehluko omkhulu.

Nawa amanyathelo awusizo ongawuthatha:

• Dla ukudla okuqondile, okuhlangene futhi ugweme ukweqa ukudla
• Hlala unamanzi ngokwanele ngokusela amanzi amaningi usuku lonke
• Thola ubuthongo obuhle, obuqondile
• Sebenzisa izindlela zokuphatha ukucindezeleka njengokuphefumula okujulile noma ukucamngca
• Gwema ukusebenzisa utshwala ngokweqile
• Qaphela imithi futhi uhlale uqondise abahlinzeki bezempilo ngesimo sakho

Gcina idayari yezimpawu ukuze ubone izici zakho siqu. Lokhu kungakusiza wena nodokotela wakho ukuba niqonde kangcono izindlela futhi nithathe izinqumo eziqondile ngokunakekelwa kwakho.

Kufanele uzilungiselele kanjani i-aphoyintimenti yakho nodokotela?

Ngaphambi kwe-aphoyintimenti yakho, buza ulwazi mayelana nezimpawu zakho, kufaka phakathi ukuthi zaqala nini nokuthi yini engase iziqalise. Lokhu kuyasiza udokotela wakho ukuba aqonde kangcono isimo sakho siqu.

Letha ulwazi olulandelayo:

• Uhlu lwemithi yamanje kanye nezinhlanganisela
• Umbukiso womndeni wezimo zesibindi noma i-Gilbert's syndrome
• Inkulumo yezimpawu kanye nokuvamile kwazo
• Noma yiziphi iziphumo zezivivinyo zegazi ezidlule
• Imibuzo mayelana neli mo kanye nokuphathwa kwalo

Ungangabazi ukubuza udokotela wakho nganoma yini ekukhathazayo. Ukuqonda isimo sakho kuyasiza ekuthambiseni ukukhathazeka futhi kukwenze ube namandla okukuphatha kahle.

Iyini into ebaluleke kakhulu mayelana ne-Gilbert's syndrome?

I-Gilbert's syndrome iyimo elithambile, elidluliselwa ngezofu, elithinta indlela isibindi sakho esiqhekeza ngayo i-bilirubin. Nakuba ingabangela izimpawu ezithile njengokuphenduka kombala olukhanyayo lwesibuko noma ukukhathala, ayinangozi futhi ayidingi ukwelashwa ezimweni eziningi.

Into ebaluleke kakhulu okumele uyikhumbule ukuthi ukuba ne-Gilbert's syndrome akukubeki engcupheni yempilo yakho. Ungaphila impilo evamile, enempilo naleli mo.

Gxila ekugcineni imikhuba yempilo enempilo, ukuqonda izici zakho, nokugcina ukuxhumana okuqondile nomhlinzeki wakho wezokunakekelwa kwezempilo. Ngalolu suku, i-Gilbert's syndrome iba yingxenye encane yephrofayili yakho yempilo kunokuba yimbangela yokukhathazeka.

Imibuzo evamile ebuzwa mayelana ne-Gilbert's syndrome

Ingaphiliswa yini i-Gilbert's syndrome?

I-Gilbert's syndrome ayikwazi ukupheliswa ngoba iyimo le-genetic oyithola kubazali bakho. Kodwa-ke, ayidingi ukupheliswa ngoba ingenangozi futhi ayilimazi isibindi lakho noma ichaphazele impilo yakho yonke. Abantu abaningi bayiphatha ngempumelelo ngokulungisa indlela yokuphila.

Ingayichaphazela yini i-Gilbert's syndrome imitha yakho?

I-Gilbert's syndrome ngokuvamile ayichaphazeli ukukhulelwa noma impilo yengane yakho. Kodwa-ke, ukuguquka kwamahomoni ngesikhathi sokukhulelwa kungase kukhulise amazinga e-bilirubin okwesikhashana. Kubalulekile ukwazisa umhlinzeki wakho wezokunakekelwa kwezempilo ngesimo sakho ukuze akwazi ukukugcina uqaphile ngokufanele futhi ahlukanise ukuguquka okujwayelekile kwe-Gilbert's syndrome kwezinye izimo ezihlobene nokukhulelwa.

Nginganikela yini igazi uma ngine-Gilbert's syndrome?

Ukuba ne-Gilbert's syndrome akukwenzi ngokuzenzakalelayo ungafanele ukunikela igazi. Kodwa-ke, kufanele wazise isikhungo sokunikela igazi ngesimo sakho. Bangase bahlole amazinga e-bilirubin yakho, futhi uma aphakame kakhulu ngesikhathi sokunikela, kungase kudingeke ulinde kuze kube yilapho ebuya emazingeni amukelekayo.

Ingadluliselwa yini i-Gilbert's syndrome emindenini?

Yebo, i-Gilbert's syndrome iyimo elidluliselwa ngezofu elihambisana nemindeni. Udinga ukudlulisela i-gene eguqukile kubazali bobabili ukuze ube naleli mo. Uma une-Gilbert's syndrome, kunamathuba ongawudlulisela kubantwana bakho, kodwa nabo kuzodingeka badlulisele i-gene komunye umzali ukuze bathuthukise leli mo.

Ingayiqalisa yini imithi ethile izimpawu ze-Gilbert's syndrome?

Nakuba ukudla okuqondile kungayiqalisi ngokuqondile i-Gilbert's syndrome, ukweqa ukudla noma ukuzila ukudla kungabangela izimpawu ukuba zivele. Okubalulekile ukugcina izindlela zokudla eziqondile kunokugwema ukudla okuqondile. Abanye abantu bathola ukuthi ukudla ukudla okuncane, okuvamile kuyasiza ekugcineni amazinga e-bilirubin aqondile futhi kuvimba izimpawu ukuba zivele.