Ubuhlungu bePaget emathanjeni: Izimpawu, Izimbangela, Nokwelapha

Ubuhlungu bePaget emathanjeni yisimo esingapheli lapho amathambo akho ekhula khona ngokushesha kakhulu futhi abe khulu, abuthakathaka, futhi angabi namfanelo. Cabanga ngakho njengoba inqubo yokwakha amathambo yomzimba wakho ingena ekuqhubeni okukhulu ezindaweni ezithile, idala amathambo amakhulu kodwa angaqinile.

Lesi simo sivame ukubathinta abantu abangaphezu kweminyaka engama-50 futhi ngokuvamile sivela emindenini. Nakuba kuzwakala kukhathaza, abantu abaningi abane-Paget's disease baphila impilo evamile, esebenzayo ngokuphathwa okuqondile nokunakekelwa.

Iyini i-Paget's Disease Yamathambo?

Ubuhlungu bePaget buhlupha inqubo yokuvuselelwa kwamathhambo yomzimba wakho. Ngokuvamile, i-tissue yamathambo amadala iphukile futhi ithathelwe indawo yi-tissue entsha yamathambo kusetshenziswa isikhathi esilinganisekile.

Ku-Paget's disease, le nqubo isheshisa kakhulu emathanjeni athile. Umgomo wakho uphula amathambo amadala ngokushesha kakhulu futhi uthathe indawo ngamathambo amasha aqala ngokushesha kakhulu. Lokhu kwakhiwa kwamathhambo okuqaphelekayo kudala i-tissue yamathambo enkulu kodwa ebuthakathaka futhi enezinkinga.

Lesi sifo sivame ukubathinta amathambo athile kunokuba kube yisikhumba sakho sonke. I-pelvis yakho, umgogodla, ikhanda, namathambo ezinyaweni yizindawo ezivame ukubathinta kakhulu.

Ziyini Izimpawu ze-Paget's Disease?

Abantu abaningi abane-Paget's disease abanawo noma yimiphi impawu, ikakhulukazi ezingxenyeni zokuqala. Uma izimpawu zivele, ngokuvamile zithuthuka kancane kancane futhi zingase zihluke kuye ngokuthi yimaphi amathambo athintekayo.

Nazi izimpawu ezivamile ongaziqaphela:

• Ubuhlungu bamathambo obuchazwa njengobunzima, obuhlungu, noma obukhulu
• Ubuhlungu lwamaqakala eduze kwamathhambo athintekayo
• Ukuthuthumela okukhulu phezu kwamathhambo athintekayo
• Ukuguqulwa kwamathhambo noma ukuguqulwa kwesimo samathambo
• Ukweqa okuvela kalula kunokulindelekile
• Izinhlungu zikhanda uma ikhanda lakho lithintekile
• Ukwehluleka kokuzwa uma amathambo ekhanda ehilelekile
• Ukugoba kwezinyawo noma ukuguqulwa komzimba

Izimpawu ezingavamile zingafaka ukucindezelwa kwama-nerve, lapho amathambo amakhulu ecindezela ama-nerve aseduze, okubangela ukungathandeki noma ukukhahlela. Abanye abantu nabo baye baba nomoya omubi, nakuba lokhu kuyingxenye encane futhi ngokuvamile kuphazanyiswa.

Ubuhlungu obuvela ku-Paget's disease ngokuvamile bubi kakhulu ebusuku futhi bungase bungaphenduli kahle emithi yokuhlanza ubuhlungu evamile. Uma uhlushwa ubuhlungu bamathambo obuqhubekayo, kufanele ukuxoxe nodokotela wakho.

Ziyini Izimbangela ze-Paget's Disease?

Imbangela eqondile ye-Paget's disease ayiqondakali ngokuphelele, kodwa abacwaningi bakholelwa ukuthi ivela ekubeni ndawonye kwezinto zofuzo nezimo ezingaphandle.

I-genes yakho idlala indima ebalulekile kulesi simo. Uma unezilwane zomndeni ezinale-Paget's disease, cishe uzoyithola wena. Ososayensi baye bathola ama-genes amaningi andisa ingozi yakho, ngokuguqulwa kwe-SQSTM1 gene njengelinye lamavamile kakhulu.

Izimo ezingaphandle zingase futhi zibangele lesi sifo kubantu abanezinto zofuzo. Abanye abacwaningi bacabanga ukuthi ukutheleleka okuthile kwe-viral ekuqaleni kokuphila kungase kuhlanganyele ekuthuthukiseni i-Paget's disease kamuva, nakuba lobu buxhumano abubonakali.

Ubudala yinto ebalulekile. Lesi simo asivame ukubathinta abantu abangaphansi kweminyaka engama-40 futhi sibe yinto evamile njengoba ukhula. Amadoda cishe anamanani aphezulu okuthola i-Paget's disease kunabesifazane.

Nini Okufanele Ubone Udokotela Ngokuphathelene ne-Paget's Disease?

Kufanele uxhumane nodokotela wakho uma uhlushwa ubuhlungu bamathambo obuqhubekayo obungaphuli ngokuphumula noma imithi yokuhlanza ubuhlungu evamile. Lokhu kubaluleke kakhulu uma ubuhlungu bukhulu, buhlungu, futhi bubi kakhulu ebusuku.

Ezinye izimpawu zokuqapha ezidinga ukunakekelwa kwezokwelapha zifaka ukuguqulwa okubonakalayo kwesimo samathambo akho, njengokugoba kwezinyawo zakho noma ukuguqulwa kwesimo sekhanda lakho. Uma uhlushwa ukweqa okungachazeki noma amathambo aphula kalula kunokulindelekile, lokhu kungase futhi kubonise i-Paget's disease.

Funani ukunakekelwa kwezokwelapha uma uthuthukisa izinkinga zokuzwa, izinhlungu zikhanda eziqhubekayo, noma izimpawu ze-neurological njengokungathandeki noma ukukhahlela ezandleni zakho noma ezinyaweni. Lezi zimpawu zingase zibonise ukuthi amathambo amakhulu athinta ama-nerve aseduze noma ezinye izakhiwo.

Uma unomlando womndeni we-Paget's disease, kufanele uxoxe ngokuhlolwa nodokotela wakho, ngisho noma ungenawo izimpawu. Ukutholakala kwangaphambi kwesikhathi kungasiza ukuvimbela izinkinga futhi kuthuthukise imiphumela yakho yesikhathi eside.

Ziyini Izinto Ezingase Zikubangele I-Paget's Disease?

Izinto eziningi zingase zikwandisa amathuba akho okuthola i-Paget's disease, ezinye zilawulwa wena kanti ezinye azilawulwa.

Izinto eziyingozi ezibaluleke kakhulu zifaka:

• Ubudala obungaphezu kweminyaka engama-50, ingozi ikhula njengoba ukhula
• Umlando womndeni wesimo
• Ukuba ngumuntu waseYurophu yaseNyakatho
• Ubulili besilisa, nakuba umehluko mncane
• Ukuphila ezindaweni ezithile lapho lesi sifo sivame khona

Ukuba nalezi zinto ezingase zikubangele lesi sifo akusho ukuthi uzoyithola ngokuqinisekile i-Paget's disease. Abantu abaningi abanezinto eziningi ezingase zikubangele lesi sifo abayitholi, kanti abanye abanezingxenye ezimbalwa ezingase zikubangele lesi sifo bayithola.

Indawo yendawo ibonakala idlala indima, ngamanani aphezulu atholakala eNgilandi, eScotland, e-Australia, nase-New Zealand. Ngokuthakazelisayo, lesi sifo siyimfihlo kakhulu e-Asia nase-Afrika, okubonisa ukuthi kokubili izinto zofuzo nezimo ezingaphandle zithinta.

Ziyini Izinkinga Ezingase Zivele Ku-Paget's Disease?

Nakuba abantu abaningi abane-Paget's disease baphila ngaphandle kwezinkinga ezinkulu, lesi simo ngezinye izikhathi singase siholele ezinkingeni ezihlupha ikhwalithi yempilo yakho nempilo yakho yonke.

Izinkinga ezivamile ongazihlangabezana nazo zifaka:

• Ukweqa, ikakhulukazi emathanjeni aphethe isisindo njengomlenze wakho
• I-Arthritis emaqakaleni eduze kwamathhambo athintekayo
• Ukuguqulwa kwamathhambo okungase kuhluphe ukunyakaza kwakho
• Ukwehluleka kokuzwa uma amathambo ekhanda ehilelekile
• Izinkinga zesimiso sezinzwa ezivela emathanjeni acindezela ama-nerve
• Izinkinga zenhliziyo ngenxa yokwanda kokugeleza kwegazi kwamathhambo athintekayo

Izinkinga ezingavamile kodwa ezinzima zingafaka umdlavuza wamathambo, nakuba lokhu kwenzeka kubantu abangaphansi kuka-1% abane-Paget's disease. Amatshe ezinso angase futhi athuthukiswe ngenxa yokwanda kwe-calcium egazini lakho ekuphulweni kwamathhambo okusheshayo.

Izindaba ezinhle ukuthi ukwelashwa okuqondile kunganciphisa kakhulu ingozi yakho yokuthuthukisa lezi zinkinga. Ukulandelela njalo nokusebenzisa imithi efanele kungasiza ekuqinisweni kwamathhambo akho futhi kuvimbele izinkinga eziningi ezingase zenzeke.

I-Paget's Disease Ihlonishwa Kanjani?

Ukuhlonishwa kwe-Paget's disease ngokuvamile kuqala ngodokotela wakho ebukeza izimpawu zakho nomlando wakho wezokwelapha, okulandelelwa yi-physical examination ukuhlola ubuhlungu bamathambo noma ukuguqulwa.

Izivivinyo zegazi ngokuvamile yisinyathelo sokuqala sokuhlonishwa. Udokotela wakho uzohlola amazinga akho e-alkaline phosphatase, avame ukuphakama ku-Paget's disease. Le nsimbi ikhula uma amathambo akho ephula futhi akhe kabusha ngokushesha.

I-X-rays inikeza ulwazi olukhulu mayelana nesakhiwo samathambo akho futhi ingabonisa ukuguqulwa okuqondile kwe-Paget's disease. Lezi zithombe zibonisa amathambo amakhulu, izindawo zokwanda kokuthi amathambo aqine, nokubukeka okuqondile kwe-“cotton wool” abantu abasebenza ngezokwelapha abakufunayo.

Ukukhiya amathambo kungase kunconywe ukuthola zonke izindawo ezithintekile kulo lonke i-skeleton yakho. Lolu vivinyo lufaka ukugcoba inani elincane le-radioactive material eliqoqwa ezindaweni zokwakhiwa kwamathhambo asebenzayo, okusiza udokotela wakho ukubona ubukhulu besifo.

Kwezinye izimo, udokotela wakho angase anconywe i-CT scan noma i-MRI ukuze athole izithombe ezinemininingwane, ikakhulukazi uma kukhona izinkinga ezithintekayo. Lezi zivivinyo zingabonisa indlela lesi sifo esithinta ngayo amaqakala aseduze, ama-nerve, noma ezinye izakhiwo.

Iyini Ukwelashwa kwe-Paget's Disease?

Ukwelashwa kwe-Paget's disease kugqame ekulawuleni izimpawu zakho, ukuvimbela izinkinga, nokunciphisa inqubo yokulungiswa kwamathhambo angavamile. Izindaba ezinhle ukuthi ukwelashwa okuphumelelayo kukhona.

Imithi ebizwa nge-bisphosphonates yiyona ukwelashwa okuyinhloko kwe-Paget's disease. Le mithi isebenza ngokucophisa inqubo yokuphula amathambo, ivumela amathambo akho ukuba akhe ngokujwayelekile. I-bisphosphonates evamile ifaka i-alendronate, i-risedronate, ne-zoledronic acid.

Udokotela wakho uzokhetha imithi engcono kakhulu ngesimo sakho esithile. Ezinye i-bisphosphonates zithathwa njengezithombe, kanti ezinye zinikwa njengeziqhamo. Izinhlobo zeziqhamo ngokuvamile zikhethwa ngoba zilula futhi zingase zibe nemiphumela emihle.

Ukuphathwa kobuhlungu yingxenye ebalulekile yokwelashwa. Udokotela wakho angase anconywe imithi ethile yokuhlanza ubuhlungu noma imithi yokulwa nokuvuvukala ukuze akusize ulawule ukungakhululeki kwakho. I-physical therapy ingasiza futhi ekuqinisweni kokunyakaza kwakho namandla.

Kwezinye izimo ezimbalwa lapho izinkinga zithuthuka khona, ukucutshungulwa kungase kudingeke. Lokhu kungafaka ukufakwa kwamaqakala e-arthritis enzima noma izinqubo zokulungisa ukuguqulwa kwamathhambo okuhlupha umsebenzi wakho.

Ungazinakekela Kanjani Ekhaya Ngokuphathelene ne-Paget's Disease?

Ukuphatha i-Paget's disease ekhaya kuhilela ukwenza izinqumo zokuphila ezisekela impilo yamathhambo akho nokuphila kwakho okuhle. Ukuguqulwa okuncane endleleni yakho yansuku zonke kungenza umehluko omkhulu endleleni ozizwa ngayo.

Ukusebenza kuyadingeka ekuqinisweni kwamathhambo akho nokunyakaza. Ukwenza umzimba okungathinti izindawo ezithintekayo njengokuhamba, ukubhukuda, noma ukuqhubela ibhayisikili kungasiza ekuqinisweni kwamathhambo akho namaqakala akho ngaphandle kokubeka ukucindezela okukhulu ezindaweni ezithintekayo.

Ukudla kudlala indima ebalulekile empilweni yamathhambo. Qiniseka ukuthi uthola i-calcium ne-vitamin D eyanele ngokudla kwakho noma izongezo. Ukudla okunama-calcium amaningi kufaka imikhiqizo yobisi, imifino eluhlaza, nokudla okuqinisiwe.

I-heat therapy ingasiza ekulawuleni ubuhlungu nokuqina. Zama ukugcoba amanzi afudumele, ama-heating pads, noma ama-warm compresses ezindaweni ezibuhlungu. Abanye abantu bathola ukuthi ukushintshanisa ukufudumeza nokubanda kunikeza impumuzo engcono kakhulu.

Dala indawo ephephile ekhaya ukuvimbela ukuwa nokweqa. Susa ama-rugs ahlongozwayo, qiniseka ukuthi kukhona ukukhanya okuhle, futhi ufake ama-grab bars ezihlanzini uma kudingeka. Njengoba amathambo athintekayo yi-Paget's disease ephula kalula, ukuvimbela ukuwa kubaluleke kakhulu.

Kufanele Uzilungiselele Kanjani Ukuya Kudokotela?

Ukulungiselela i-appointment yakho kungasiza ekuqinisekiseni ukuthi uthola okuningi ngesikhathi sakho nodokotela wakho futhi uthole ukunakekelwa okuhle kakhulu kwesimo sakho.

Bhala zonke izimpawu zakho, kufaka phakathi ukuthi zaqala nini, yini eyenza zibe ngcono noma zimbi, nokuthi zikuthinta kanjani imisebenzi yakho yansuku zonke. Chaza ngokucacile amazinga obuhlungu bakho nanoma yikuphi ukuguqulwa okuqaphelekile emathanjeni akho noma ukunyakaza kwakho.

Letha uhlu oluphelele lwazo zonke imithi oyithathayo, kufaka phakathi imithi evamile, izongezo, nama-vitamins. Lolu lwazi lusiza udokotela wakho ukugwema ukusebenzisana okungenzeka futhi uqonde ukuthi yikuphi ukwelashwa osele ukhulu.

Buka umlando wezokwelapha womndeni wakho, ikakhulukazi noma yimiphi izihlobo ezazi-Paget's disease noma ezinye izimo zamathambo. Lolu lwazi lungabaluleka ekuxilongeni kwakho nasekulungiseni ukwelashwa.

Lungiselela uhlu lwemibuzo ofuna ukuyibuza. Cabanga ukubuza ngezinketho zokwelashwa, imiphumela engase ibe khona, ukuguqulwa kokuphila, nokuthi yini okulindelekile esikhathini esizayo. Ungangabazi ukucela incazelo uma kukhona okungacaci.

Letha umngani othembekile noma ilungu lomndeni uma kungenzeka. Bangakusiza ukukhumbula ulwazi olukhulu futhi banikeze ukwesekwa ngokomzwelo ngesikhathi se-appointment yakho.

Iyini Iphuzu Eliyinhloko Mayelana ne-Paget's Disease?

Ubuhlungu bePaget emathanjeni yisimo esilawuleka esithinta indlela amathambo akho akhula futhi azilungisa ngayo. Nakuba kungabangela ubuhlungu nezinkinga, ukwelashwa okuphumelelayo kukhona ukuze kusize ugcine ikhwalithi yempilo enhle.

Into ebaluleke kakhulu okumele uyikhumbule ukuthi ukuhlonishwa kwangaphambi kwesikhathi nokwelashwa kungavimbela izinkinga eziningi ezinkulu ezihlotshaniswa nalesi simo. Uma uhlushwa ubuhlungu bamathambo obuqhubekayo noma unomlando womndeni we-Paget's disease, ungangabazi ukuxoxa ngakho nodokotela wakho.

Ngokunakekelwa kwezokwelapha okuqondile, ukuguqulwa kokuphila, nokulandelela njalo, abantu abaningi abane-Paget's disease bangqhubeka bephila impilo esebenzayo, ezele. Ikhona ukusebenzisana eduze neqembu lakho lokunakekelwa kwezokwelapha ukuthola indlela yokwelashwa ehambisana nawe.

Imibuzo Evamile Mayelana ne-Paget's Disease

Ingabe i-Paget's disease iyefa?

Yebo, i-Paget's disease inenzuzo enkulu yofuzo. Uma unelungu lomndeni lokuqala elinayo le simo, ingozi yakho cishe iphakeme izikhathi ezingu-7 kunabantu abavamile. Noma kunjalo, ukuba nenzuzo yofuzo akusho ukuthi uzoyithola lesi sifo.

Ingabe i-Paget's disease ingelashwa?

Nakuba ayikho imithi ye-Paget's disease, ingaphathwa kahle ngokwelashwa. Imithi ye-Bisphosphonate inganciphisa kakhulu ukuqhubeka kwalesi sifo futhi ngokuvamile inikeza impumuzo ehlala isikhathi eside ekuhluphekeni. Abantu abaningi bathola ukulawulwa okuhle kwesimo sabo ngokwelashwa okuqondile.

Ingabe i-Paget's disease ithonya isikhathi sokuphila?

Kubantu abaningi, i-Paget's disease ayithinti kakhulu isikhathi sokuphila. Lesi simo ngokuvamile silawuleka ngokwelashwa, futhi izinkinga eziningi zingavikeleka ngokunakekelwa okuqondile. Kuphela kwezinye izimo ezimbalwa lapho izinkinga ezinkulu zithuthuka khona lesi sifo singase sibe nomthelela ekuphileni isikhathi eside.

Ingabe ukudla kungasiza ngobuhlungu bePaget?

Nakuba ukudla kudwa kungelaphi i-Paget's disease, ukugcina ukudla okuhle kusekela impilo yamathhambo. Qiniseka ukuthi uthola i-calcium ne-vitamin D eyanele, futhi ugcine ukudla okuhle okunomkhiqizo, imifino, nama-grains aphelele. Abanye abantu bathola ukuthi ukunciphisa ukudla okubangela ukuvuvukala kusiza ekulawuleni ubuhlungu.

Kufanele ngibone kangakanani udokotela uma ngine-Paget's disease?

Ukuvamile kwe-follow-up appointments kuncike esimweni sakho somuntu siqu nasekuphenduleni kokwelashwa. Ekuqaleni, ungase ubona udokotela wakho izinyanga ezimbalwa ukuze uqaphele ukuphumelela kokwelashwa. Uma isimo sakho siqondile, ukuhlola minyaka yonke ngokuvamile kwanele, kanye nezivivinyo zegazi eziqhubekayo ukuze uqaphele amazinga akho e-alkaline phosphatase.