Pemphigus
Uhlolojikelele
IPemphigus uhlobo lwezifo ezimbalwa zesikhumba oluphazamisa ukukhula kwamabhulashi esikhumbeni nakwimigqomo yemigqomo. Uhlobo oluvamile kakhulu yi-pemphigus vulgaris, ehilela amaqhuzu nokuqhuma okuhlungu esikhumbeni nasemlonyeni.
IPemphigus foliaceus ngokuvamile ayithinti imigqomo yemigqomo. Amabhulashi angaqala ebusweni nasekhanda bese ebonakala esifubeni nasemuhlane. Angaba namaqanda, akhuphe futhi ahlungu.
IPemphigus yiqembu lezehlakalo ezimbalwa zesikhumba ezibangela amabhulashi namaqhuzu esikhumbeni noma emigqomweni yemigqomo, njengasemlonyeni noma ezingxenyeni zocansi. Ivame kakhulu kubantu abaneminyaka ephakathi noma abadala.
IPemphigus kulula ukuyilawula uma itholakala futhi iphelelwe ngokushesha. Ngokuvamile iphelelwa ngemithi oyithatha isikhathi eside. Amaqhuzu angaphola kancane noma angapholi nhlobo. Isimo singaba yingozi eyingozi uma amaqhuzu etheleleka.
Izimpawu
I-Pemphigus ibanga amabhabha ezikhathini nasemahlathini. Amabhabha aphuka kalula, ashiya amanxeba avulekile. Amanxeba angatheleleka futhi akhiphe. Izimpawu zezinhlobo ezimbili ezivamile ze-pemphigus zingeziningi: I-Pemphigus vulgaris. Lo mkhuba ngokuvamile uqala ngamabhabha emlonyeni bese uya ezikhathini noma emahlathini esitho sobulili. Zivame ukuba buhlungu kodwa azikhohlisi. Amabhabha emlonyeni noma egqaleni angenza kube nzima ukukhuluma, ukuphuza nokudla. I-Pemphigus foliaceus. Lo mkhuba ubanga amabhabha esifubeni, emuva nasemahlombe. Amabhabha angakhohlisa noma abe buhlungu. I-Pemphigus foliaceus ayibangeli amabhabha emlonyeni. I-Pemphigus ihlukile ku-bullous pemphigoid, okuyisimo esinye sokuqhuma kwesikhumba esithinta abantu abadala. Bheka ochwepheshe bezempilo uma unemabhabha angapholi emlonyeni noma ezikhathini noma emahlathini esitho sobulili.
Isikhathi sokubona udokotela
Bona udokotela noma omunye ochwepheshe wezempilo uma unezibilini ezingapholi emlonyeni, ebuswini noma emagxalabeni esitho sobulili.
Izimbangela
IPemphigus uhlobo lwesifo sokuzimela komzimba, okusho ukuthi isimo sakho sokuvikela umzimba sihlasele ngephutha amangqamuzana aphilile emzimbeni wakho. NgoPemphigus, isimo sokuvikela umzimba sihlasele amangqamuzana esikhini nakwimigqomo yemigqomo. IPemphigus ayidluliselwa komunye umuntu. Ezimweni eziningi, akukaziwa ukuthi yini ebangela ukuba lesi sifo sivele. Ngokungavamile, lesi sifo singathuthuka njengomphumela wamayeza, njengepenicillamine namayeza athile egazini. Lolu hlobo lwesimo luvamise ukuhlanzeka uma iyeza limiswa.
Izici eziyingozi
Ingozi yokuthola i-pemphigus iyanda uma ungumuntu ophakathi nako noma omdala. Lesi simo sijwayelekile nakwabantu abangamaJuda, abangama-India, abavela eningizimu-mpumalanga yeYurophu noma abavela eMpumalanga Ephakathi.
Izingqinamba
Izingozi ezingase zenzeke ngenxa yepemphigus zihlanganisa:
- Ukutheleleka kwesikhumba.
- Ukutheleleka okudlulela egazini, okubizwa nangokuthi i-sepsis. Lolu hlobo lokutheleleka lungaba yingozi eyingozi empilweni.
- Amabala ezikhumba kanye nokuhluka kombala wesikhumba ngemva kokuba isikhumba esithintekile siphilisile. Lokhu kubizwa ngokuthi yi-postinflammatory hyperpigmentation uma isikhumba simnyama futhi yi-postinflammatory hypopigmentation uma isikhumba sililahlekelwe umbala. Abantu abanesikhumba esimnyama noma abamnyama banengozi enkulu yokushintsha kombala wesikhumba isikhathi eside.
- Ukondleka okungalungile, ngoba izilonda ezubuhlungu emlonyeni kwenza kube nzima ukudla.
- Ukufa, ngokungavamile, uma izinhlobo ezithile zepemphigus ziyekezelwa.
Ukuxilongwa
Uchwepheshe wakho wezokunakekelwa kwezempilo angase aqhale ngokukhuluma nawe ngomlando wakho wezokwelapha kanye nezimpawu bese ahlola indawo eathintekile. Ngaphezu kwalokho, ungase ube nezivivinyo, okuhlanganisa:
- I-biopsy. I-biopsy inqubo yokususa isampula yethishu ukuze ihlungwe elabhoratri. Ukuhlola i-pemphigus, kusetshenziswa ingxenye yeblister.
- Izivivinyo zegazi. Inhloso eyodwa yalezi zivivinyo ukubona nokuqonda ama-antibodies egazini lakho aqondene ne-pemphigus.
Uchwepheshe wakho wezokunakekelwa kwezempilo angase akubhekisele kudokotela ochwepheshe ezimweni zesikhumba. Lo mqondo ochwepheshe ungudokotela wezisu.
Ukwelashwa
Ukwelapha i-pemphigus kuqala ngokuvamile ngemithi ehlanganisa izimpawu futhi kuvimbele amabhabhalazi amasha. Lokhu kungafaka ama-steroids nemithi ehlose uhlelo lokukhulula. Uma izimpawu zakho zibangelwe ukusetshenziswa kwemithi ethile, ukuyeka leyo mithi kungaba ngokwanele ukusula izimpawu zakho.
Abanye abantu bangadinga ukuhlala esibhedlela ukuze bathole izinto ezinwetshiwe, ukudla noma ezinye izindlela zokwelapha.
Uchwepheshe wakho wezokunakekelwa kwezempilo angakuncoma olunye noma ngaphezulu kwalemithi elandelayo. Ukukhetha kwemithi kuncike ohlotsheni lwe-pemphigus onayo, ukuthi izimpawu zakho zinzima kangakanani nokuthi unezinye izimo zezokwelapha yini.
- Ama-Corticosteroids. Kubantu abanesifo esilula, ikhilimu ye-corticosteroid noma ukugonywa kungaba ngokwanele ukuyilawula. Kwabanye, ukwelashwa okuyinhloko yimithi ye-corticosteroid ethathwa ngomlomo, njengepheleli le-prednisone.
Ukusebenzisa ama-corticosteroids isikhathi eside noma ngamathani aphezulu kungabangela imiphumela emibi eqinile. Lokhu kufaka i-diabetes, ukulahleka kwamathambo, ingozi enkulu yokutheleleka, isifo sohlangothi lwesisu kanye nokuhluka komthamo womzimba. Lokhu kuhluka komthamo womzimba kungabangela ubuso obukhulu, okuthiwa futhi yi-moon face. Ukuze ugweme le miphumela emibi, ama-steroids angase asebenziswe kuphela isikhathi esifushane ukulawula ukuphepha. Futhi ezinye izidakamizwa ezinhloso uhlelo lokukhulula zingasetshenziswa isikhathi eside ukulawula isifo.
- Imithi ehlose uhlelo lokukhulula. Ezinye izidakamizwa zingayeka uhlelo lokukhulula lwakho ekulweni nezinhlangothi ezempilo. Izibonelo yi-azathioprine (Imuran, Azasan), i-mycophenolate (Cellcept) ne-cyclophosphamide. Lezi nazo zingaba nemiphumela emibi eqinile, kufaka phakathi ingozi enkulu yokutheleleka.
- Ezinye izidakamizwa. Uma imithi yokuqala ingakusizi, uchwepheshe wakho wezokunakekelwa kwezempilo angakuncoma olunye ubuhlungu, njenge-dapsone, i-immunoglobulin ye-intravenous noma i-rituximab-pvvr (Ruxience). Ungadinga ama-antibiotics ukwelapha ukutheleleka.
Ama-Corticosteroids. Kubantu abanesifo esilula, ikhilimu ye-corticosteroid noma ukugonywa kungaba ngokwanele ukuyilawula. Kwabanye, ukwelashwa okuyinhloko yimithi ye-corticosteroid ethathwa ngomlomo, njengepheleli le-prednisone.
Ukusebenzisa ama-corticosteroids isikhathi eside noma ngamathani aphezulu kungabangela imiphumela emibi eqinile. Lokhu kufaka i-diabetes, ukulahleka kwamathambo, ingozi enkulu yokutheleleka, isifo sohlangothi lwesisu kanye nokuhluka komthamo womzimba. Lokhu kuhluka komthamo womzimba kungabangela ubuso obukhulu, okuthiwa futhi yi-moon face. Ukuze ugweme le miphumela emibi, ama-steroids angase asebenziswe kuphela isikhathi esifushane ukulawula ukuphepha. Futhi ezinye izidakamizwa ezinhloso uhlelo lokukhulula zingasetshenziswa isikhathi eside ukulawula isifo.
Abantu abaningi abane-pemphigus bayaphila, ikakhulukazi uma ukwelashwa kuqalwa ngokushesha. Kodwa kungathatha iminyaka futhi kungadingeka ukuthatha imithi isikhathi eside.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.