Uyini i-Synovial Sarcoma? Izimpawu, Izimbangela, Nokwelashwa

I-synovial sarcoma uhlobo oluyimfihlo lomdlavuza olukhula ezihlangeni ezithambile, ikakhulukazi eduze kwamajozi njengemadolo, izingalo, amahlombe, nezinqindi. Naphezu kwegama layo, lo mdlavuza awuhlali eqala esicini se-synovial esigcwalisa amajozi akho. Kunalokho, ungakhula kuphi lapho kuhlala khona izicubu ezithambile zomzimba wakho, kufaka phakathi imisipha, izintambo, namanoni.

Lesi simo sithinta abantu abalinganiselwa ku-1,000 kuya ku-1,500 e-United States unyaka ngamunye, okwenza kube yinto engavamile. Nakuba ukuxilongwa kungase kuzwakale kukhulu, ukuqonda ukuthi yini oyiphathayo kungakusiza uzizwe ulungile futhi unamandla njengoba uqhuba ukunakekelwa kwakho.

Ziyini izimpawu ze-synovial sarcoma?

Isinyathelo sokuqala esivamile yilump noma ukukhula okungenaphimbo ongakwazi ukulizwa ngaphansi kwesikhumba sakho. Abantu abaningi bayabona lo mkhula eduze komjovo, nakuba ungase ubonakale kuphi lapho emzimbeni wakho.

Nazi izimpawu ongazihlangabezana nazo njengoba isimo sikhula:

• Umklamo oluqinile, olukhula olukhulu ongaholela ebuhlungwini noma ungabi nalo.
• Ukukhula endaweni ethintekile.
• Ukunciphisa ukunyakaza kwamajozi aseduze.
• Ubuhlungu obukhula ngokuhamba kwesikhathi, ikakhulukazi ebusuku.
• Ukukhahlela noma ukukhahlela uma i-tumor icindezela izinzwa.
• Ubuthakathaka eluthweni oluthintekile.

Into enzima mayelana ne-synovial sarcoma ukuthi ivame ukukhula kancane futhi ingase ingabangeli ubuhlungu ekuqaleni. Lokhu kusho ukuthi abanye abantu bangase bayidedise ilump njengokulimala okuncane noma ukucindezela. Uma ubona noma yikuphi ukukhula okumi noma imiklamo, ikakhulukazi leyo eyaqhubeka ikhula, kufanele uyihlolisise ngudokotela wakho.

Ziyini izinhlobo ze-synovial sarcoma?

Odokotela bahlukanisa i-synovial sarcoma zibe izinhlobo ezintathu eziyinhloko ngokusekelwe ekutheni amaseli abonakala kanjani ngaphansi komkhulu. Ukuqonda uhlobo lwakho oluthile kusiza iqembu lakho lezokwelapha ukuhlela indlela yokwelapha engcono kakhulu kuwe.

Uhlobo lwe-biphasic lubandakanya izinhlobo ezimbili zamaseli ezibukeka zihlukile komunye nomunye. Uhlobo lwe-monophasic lunezisele ezibukeka zifana komunye nomunye. Uhlobo oluhlukile kakhulu lunezisele ezibukeka zingavamile futhi azifani namacubu amaseli avamile.

I-pathologist yakho izonquma ukuthi yiluphi uhlobo olukhona ngemuva kokuhlola isampula yecubu. Lolu lwazi, kanye nezinye izinto njengobukhulu be-tumor nendawo, kusiza ukuqondisa uhlelo lwakho lokwelapha.

Yini ebangela i-synovial sarcoma?

Imbangela eqondile ye-synovial sarcoma ayiqondakali ngokuphelele, kodwa abacwaningi baye bathola izinkomba ezibalulekile. Izimo eziningi zihlanganisa ushintsho oluthile lwe-genetic oluthiwa yi-chromosomal translocation, lapho izingcezu zekromosomu ezimbili zishintshana khona.

Lolu shintsho lwe-genetic aluyona into oyithola kubazali bakho. Kunalokho, kwenzeka phakathi nokuphila kwakho, mhlawumbe ngengozi. I-translocation idala i-protein engavamile eyalela amaseli ukuba akhule futhi ahlukanise lapho kungafanele.

Ngokungafani nezinye izinhlobo zomdlavuza, i-synovial sarcoma ayibonakali ihlobene nezinto zokuphila njengokubhema, ukudla, noma ukukhanya kwelanga. Izinto ezingaphandle njengokukhanya kweradieysheni kungase kudlale indima ezimweni ezingavamile kakhulu, kodwa kubantu abaningi, ayikho imbangela ecacile ongaba uyigweme.

Nini okufanele ubona udokotela nge-synovial sarcoma?

Kufanele uhlele i-aphoyintimenti nodokotela wakho uma ubona noma yiluphi lump noma ukukhula okuqhubeka amasonto ambalwa. Nakuba imiklamo eminingi iphuma ingabi yingozi, kuhlale kungcono ukuyihlengisa ekuqaleni.

Funani ukunakekelwa kwezokwelapha ngokushesha uma uhlangabezana nokukhula okusheshayo komkhulu, ubuhlungu obukhulu obuphazamisa imisebenzi yansuku zonke, noma ukukhahlela nobuthakathaka ezithweni zakho. Lezi zimpawu zingase zibonise ukuthi i-tumor icindezela izakhiwo ezibalulekile njengezinzwa noma imithambo yegazi.

Ungakhathazeki ngokubonakala uqapha kakhulu. Umhlinzeki wakho wezempilo angathanda kakhulu ukuhlola ilump elingenangozi kunokulahlekelwa ithuba lokuqala lokuxilonga nokuphatha into enkulu kakhulu. Ukutholakala ekuqaleni kuvame ukholela eziphumeleni zokwelapha ezingcono.

Ziyini izinto ezingase zikwenze kube lula ukuba ne-synovial sarcoma?

I-synovial sarcoma ingathinta noma ubani, kodwa izinto ezithile zingase zikwenze kube lula ukuba neli simo. Ukuqonda lezi zinto ezingase zikwenze kube lula ukuba neli simo kungakusiza uhlale uqaphile, nakuba kubalulekile ukukhumbula ukuthi ukuba nezinto ezingase zikwenze kube lula ukuba neli simo akusho ukuthi uzoba nomdlavuza ngokuqinisekile.

Ubudala budlala indima, ngezimo eziningi ezenzeka kubantu abaneminyaka engama-15 kuya kwengu-40. Noma kunjalo, i-synovial sarcoma ingakhula kunoma yimuphi ubudala, kufaka phakathi ezinganeni nasezikhulile. Ubulili futhi bubalulekile kancane, njengoba lo mdlavuza uthinta amadoda kakhulu kunabesifazane.

Ukuphathwa kwangaphambili kwemisebe yomdlavuza omunye kungase kukwenze kube lula ukuba neli simo, nakuba lokhu kubalwa kuphela ingxenye encane kakhulu yezimo. Abantu abaningi abane-synovial sarcoma abanazo izinto ezingase zikwenze kube lula ukuba neli simo ezibonakalayo nhlobo, okuqinisekisa ukuthi lo mdlavuza ngokuvamile ukhula ngengozi kunokuba kube ngenxa yokukhanya okukhethekile noma ukuziphatha.

Ziyini izinkinga ezingase zenzeke nge-synovial sarcoma?

Ukukhathazeka okuyinhloko nge-synovial sarcoma ukuthi ingasakazeka kwezinye izingxenye zomzimba wakho uma ingaphathwa ngokushesha. Amaphaphu yindawo evamile lapho lo mdlavuza usakazeka khona, nakuba ungase futhi uthinte ama-lymph nodes namagagasi.

Izinkinga zendawo zingase zikhule lapho i-tumor ikhula ngokwanele ukucindezela izakhiwo eziseduze. Ungase uhlangabezane nokulimala kwezinzwa okuholela ekukhahleleni noma ebuthakathakeni, ukucindezelwa kwemithambo yegazi okubangela ukukhula, noma izinkinga zamajozi uma i-tumor ithonya ukunyakaza kwakho.

Ukuphathwa ngokwako ngezinye izikhathi kungabangela izinkinga, nakuba iqembu lakho lezokwelapha lisebenza kanzima ukuze linciphise lezi ngozi. Ukuhlinzwa kungase kube yimbangela yobunqunu noma ubuthakathaka besikhashana, kuyilapho i-chemotherapy ne-radiation zingase zibangele ukukhathala nezinye izingozi ezodokotela bakho abazokusiza uzilawule.

Izindaba ezinhle ukuthi izinkinga eziningi zingaqalekelwa noma ziphathwe kahle ngokunakekelwa kwezokwelapha okufanele. Iqembu lakho lezokwelapha lizokugcina liqaphile futhi liqaphe noma yiziphi izinkinga ezivela endleleni.

I-synovial sarcoma ixilongwa kanjani?

Ukuxilonga i-synovial sarcoma ngokuvamile kuqala ngudokotela wakho ehlola ilump futhi ebuza ngezimpawu zakho. Bazofuna ukwazi ukuthi uqaphele kangakanani umkhulu, ukuthi ukhule yini, nokuthi uhlangabezana nobuhlungu noma ezinye izimpawu.

Izivivinyo zokuthola izithombe zisiza udokotela wakho ukubona i-tumor ngokucacile futhi anqume ubukhulu nendawo yayo. I-MRI scan inikeza izithombe eziningi zezicubu ezithambile futhi ibonisa ukuthi i-tumor ihlobene kanjani nemisipha, izinzwa, nemithambo yegazi eseduze. I-CT scans ingase isetshenziswe ukuhlola ukuthi umdlavuza usakazeke yini emaphaphwini akho noma kwezinye izitho.

Ukuxilongwa okuqinisekile kuvela e-biopsy, lapho ingxenye encane ye-tumor isuswa futhi ihlolwe ngaphansi komkhulu. Udokotela wakho angase enze i-needle biopsy esebenzisa i-needle encane, noma i-surgical biopsy lapho benza khona isiqu esincane ukususa icubu.

Izivivinyo ezikhethekile ze-genetic ku-biopsy sample zingase ziqinisekise ukuxilongwa ngokubuka ushintsho lwe-chromosomal oluvamile olutholakala kwi-synovial sarcoma. Lezi zivivinyo zisiza ukuhlukanisa lo mdlavuza kwezinye izinhlobo zama-tumors ezithambile.

Yikuphi ukwelashwa kwe-synovial sarcoma?

Ukuphathwa kwe-synovial sarcoma ngokuvamile kubandakanya ukuhlanganiswa kwezindlela ezilungiselelwe isimo sakho esithile. Ukuhlinzwa ngokuvamile kuyindlela eyinhloko yokwelapha, okuqondiswe ekususeni yonke i-tumor kanye nezinye izicubu ezisempilweni ezizungezile ukuze kuqinisekiswe imingcele ecacile.

Iqembu lakho lokuhlinzwa lizo sebenza ngokucophelela ukuze ligcine umsebenzi ovamile ngangokunokwenzeka ngenkathi lisusa ngokuphelele umdlavuza. Ezimweni eziningi, ukuhlinzwa kokulondoloza uhlangothi kungase kuphumelele ekususeni i-tumor ngaphandle kokudinga ukunqunywa. Noma kunjalo, indlela yokwelapha eyiyo ihlala ixhomeke ebukhulu be-tumor, indawo, nobudlelwano bezakhiwo ezibalulekile.

I-Chemotherapy ngokuvamile idlala indima ebalulekile, ngaphambi kokuhlinzwa ukuze inciphise i-tumor noma ngemuva kokuhlinzwa ukususa noma yimaphi amaseli omdlavuza asaleyo. Imithi evamile esetshenziswayo ihlanganisa i-doxorubicin ne-ifosfamide, ebonise imiphumela emihle ngokumelene ne-synovial sarcoma.

I-Radiation therapy ingase icelwe ukuze inciphise ingozi yokubuyela komdlavuza endaweni efanayo. Lolu lwelo lwasebenzisa imisebe yamandla aphezulu ukuqondisa noma yimaphi amaseli omdlavuza amancane angase asele ngemuva kokuhlinzwa. I-radiation oncologist yakho izohlela ukwelashwa ngokucophelela ukuze inciphise imiphumela ezicubeni ezempilo.

Ungazilawula kanjani izimpawu ekhaya ngesikhathi sokwelashwa?

Ukuphatha izimpawu zakho ekhaya kungakusiza uzizwe ukhululekile futhi ugcine amandla akho ngesikhathi sokwelashwa. Ukuphathwa kobuhlungu ngokuvamile kuyinto ebalulekile, futhi udokotela wakho angakubhalela imithi efanele ngenkathi ephakamisa izindlela ezingelona imithi njengokushisa, ukubanda, noma ukunyakaza okuthambile.

Ukusebenza ngaphakathi kwemingcele yakho kusiza ukugcina amandla emisipha nokuqina kwamajozi. I-physical therapist yakho ingakufundisa imisebenzi ekhethekile ephephile futhi enenzuzo isimo sakho. Ngisho nemisebenzi elula njengokuhamba noma ukwelula okuthambile kungenza umehluko omkhulu endleleni ozizwa ngayo.

Ukudla okufanele kusekela ukululama komzimba wakho futhi kukusiza ubekezelele ukwelashwa kangcono. Gxila ekudleni ukudla okuvamile, okuqondile ngisho noma isisindo sakho singase sithinteke ukwelashwa. Ukudla okuncane, okuvamile ngokuvamile kusebenza kangcono kunokuzama ukudla izingxenye ezinkulu.

Ungangabazi ukucela usizo ngemisebenzi yansuku zonke lapho udinga khona. Ukuba nokusekelwa komndeni nabangane kunganciphisa ukucindezeleka kwakho futhi kukuvumele ubeke amandla akho ekululameni.

Kufanele uzilungiselele kanjani i-aphoyintimenti yakho nodokotela?

Ukulungiselela i-aphoyintimenti yakho kungakusiza ukwenze kakhulu isikhathi sakho neqembu lakho lezokwelapha. Bhala zonke izimpawu zakho, kufaka phakathi lapho uqale ukuzibona khona nokuthi zishintshe kanjani ngokuhamba kwesikhathi. Lolu lwazi lusiza udokotela wakho ukuqonda isimo sakho kangcono.

Letha uhlu lwemithi yonke oyithathayo, kufaka phakathi imithi yokuthengwa ngaphandle komthetho kanye nezinye izinto. Buye uqoqe noma yimaphi amarekhodi ezempilo wangaphambili noma imiphumela yezivivinyo ehlobene nezimpawu zakho zamanje, njengoba lezi zingase zinikeze ulwazi oluwusizo ekunakekelweni kwakho.

Lungiselela uhlu lwemibuzo ofuna ukuyibuza udokotela wakho. Ungase ufune ukwazi ngezindlela zokwelapha, izingozi, i-prognosis, noma ukuthi isimo singase lithinte kanjani impilo yakho yansuku zonke. Ukubhala lokhu phansi kuqinisekisa ukuthi ngeke ukhohlwe imibuzo ebalulekile ngesikhathi se-aphoyintimenti yakho.

Cabanga ukuletha ilungu lomndeni omethembayo noma umngani e-aphoyintimenti yakho. Bangase banikeze ukusekelwa ngokomzwelo futhi bakusize ukukhumbula ulwazi oluqakathekile oluxoxwe ngesikhathi sokuvakasha kwakho.

Iyini into ebalulekile mayelana ne-synovial sarcoma?

I-synovial sarcoma uhlobo oluyimfihlo kodwa oluphulukiswayo lomdlavuza oluvamile oluvela njengelump elikhula eduze kwamajozi noma ezihlangeni ezithambile. Nakuba ukwamukela lo mxilongo kungase kuzwakale kukhulu, abantu abaningi abane-synovial sarcoma baqhubeka bephila impilo egcwele, esebenzayo ngemuva kokwelashwa.

Ukutholakala ekuqaleni nokuphathwa kunikeza imiphumela engcono kakhulu, kungakho kubalulekile ukuba noma yiluphi lump oluqhubekayo noma ukukhula kuhlolwe udokotela wakho. Izindlela zokwelapha zanamuhla, kufaka phakathi izindlela zokuhlinzwa eziqandile kanye ne-chemotherapy ephumelelayo, ziye zathuthukisa kakhulu imiphumela yabantu abaneli simo.

Khumbula ukuthi awuwedwa kule ndlela. Iqembu lakho lezokwelapha lilapho ukuqondisa kuzo zonke izinyathelo zokwelashwa kwakho nokululama kwakho. Ungangabazi ukubuza imibuzo, ubonise ukukhathazeka, noma ufuna ukusekelwa lapho udinga khona.

Imibuzo evame ukubuzwa mayelana ne-synovial sarcoma

Ingabe i-synovial sarcoma ihlale ibulawa?

Cha, i-synovial sarcoma ayihlali ibulawa. Abantu abaningi abaneli simo baphathwa ngempumelelo futhi baqhubeka bephila impilo evamile. I-outlook ixhomeke ezintweni njengobukhulu be-tumor, indawo, nokuthi isakazeke yini lapho ixilongwe. Ukutholakala ekuqaleni nokuphathwa kuthuthukisa kakhulu imiphumela.

Ingabe i-synovial sarcoma ingabuya ngemuva kokwelashwa?

Yebo, i-synovial sarcoma ingabuya, kungakho ukunakekelwa okuqhubekayo kubalulekile. Ukubuyela okuningi kwenzeka eminyakeni embalwa yokuqala ngemuva kokwelashwa. Iqembu lakho lezokwelapha lizokuhlela ukuhlola okuvamile kanye nezivivinyo zokuthola izithombe ukuze liqaphe noma yiziphi izimpawu zokubuyela. Uma ibuya, kunezindlela zokwelapha ezengeziwe ezitholakalayo.

Ingabe i-synovial sarcoma ihamba emindenini?

Cha, i-synovial sarcoma ayilona isimo esidluliselwa ezizukulwaneni. Ushintsho lwe-genetic olubangela lo mdlavuza lwenzeka phakathi nokuphila komuntu kunokuba kudluliselwe kubazali. Ukuba nelungu lomndeni eline-synovial sarcoma akukwenzi kube lula ukuba neli simo.

I-synovial sarcoma ikhula ngokushesha kangakanani?

I-synovial sarcoma ngokuvamile ikhula kancane, kungakho abantu bengase bangaziboni izimpawu ngokushesha. Noma kunjalo, amazinga okukhula angase ahluke phakathi kwabantu. Ezinye i-tumors zihlala zinzima izinyanga noma iminyaka, kuyilapho ezinye zingase zikhule ngokushesha. Kungakho noma yiluphi lump oluqhubekayo kufanele luhlolwe ngokushesha.

Ingabe i-synovial sarcoma ingavikeleka?

Okwamanje, ayikho indlela eyaziwayo yokuvimbela i-synovial sarcoma njengoba ikhula ngenxa yoshintsho lwe-genetic oluzenzakalelayo kunokuba kube ngenxa yezinto zokuphila. Indlela engcono kakhulu iwukuqaphela izinguquko emzimbeni wakho futhi ufunani ukunakekelwa kwezokwelapha nganoma yiluphi lump olusha oluqhubekayo noma izimpawu. Ukutholakala ekuqaleni kuhlala kuyinto ebaluleke kakhulu ekufezeni imiphumela emihle.