Iyini i-Systemic Mastocytosis? Izimpawu, Izimbangela, & Ukwelashwa

I-Systemic mastocytosis yisimo esingavamile lapho umzimba wakho ukhulisa khona ama-mast cells amaningi kakhulu, okuyizicubu ezikhethekile ze-immune system ezivame ukusivikela ekuthelelekeni nase-allergens. Uma uneleli simo, lezi zicubu ziyakha ezingutsheni ezahlukene emzimbeni wakho, kufaka phakathi u-bone marrow, isikhumba, isibindi, ispleen, kanye nesistimu yokugaya ukudla.

Cabanga ngama-mast cells njengabaphathi bekhwalithi yomzimba wakho. Bakhipha izinto ezifana ne-histamine uma bethola ubungozi. Ku-systemic mastocytosis, unezinye zezi ziphathi, futhi ngezinye izikhathi zingakhipha amakhemikhali azo ngisho noma kungekho luvalo olukhulu, okubangela izimpawu ezahlukene emzimbeni wakho.

Ziyini izimpawu ze-systemic mastocytosis?

Izimpawu ze-systemic mastocytosis zingase zihluke kakhulu kumuntu nomuntu ngoba leli simo lithinta izinhlelo eziningi zomzimba. Abantu abaningi baye baba nezimpawu eziphuma bese zibuya, kanti abanye bangaba nezinkinga ezihlala njalo.

Nawa zimpawu ezivamile ongazihlangabezana nazo:

• Ukucasuka kwesikhumba njengokubopha, ukukhahlela, noma ukukhishwa okungase kuvele ngokuzumayo
• Izinkinga zokugaya ukudla kufaka phakathi isicanucanu, ukugabha, isifo sohudo, noma ubuhlungu besisu
• Ubuhlungu lwamathambo namalunga, ikakhulukazi emhlane, ezinqeni, noma ezinhlangothini
• Ukukhathala okungaphuli ngokuphumula
• Izinhlungu zikhanda ezingase zibe ezahlukene nezinhlungu zakho zikhanda eziqhelile
• Ukushona kwenhliziyo noma ukuzwa sengathi inhliziyo yakho iyagijima
• Ubunzima bokuqonda noma ukungakhulumisani kahle

Abanye abantu nabo baye baba nezimpawu ezinkulu ezidinga ukunakekelwa ngokushesha kwezokwelapha. Lokhu kungafaka phakathi ukucasuka okukhulu kwe-allergic, ubunzima bokuqeda umoya, noma ukwehla okungazelelwe kwezinga lokucindezela kwegazi. Nakuba lezi zenzakalo ezinkulu zingavamile, zingase zenzeke futhi kubalulekile ukwazi izimpawu zezexwayiso.

Ungase ubone ukuthi izinto ezithile ezikhuthazayo njengokucindezeleka, ukudla okuthile, imithi, noma ngisho nokuhluka kwezinga lokushisa kungenza izimpawu zakho zibe zimbi. Lokhu kwenzeka ngoba lezi zinto ezikhuthazayo zingabangela ama-mast cells akho ukuba akhiphe amakhemikhali awo amaningi.

Imiphi imikhakha ye-systemic mastocytosis?

I-Systemic mastocytosis iza ngezindlela eziningi ezahlukene, nokuqonda ukuthi yiluphi uhlobo olukuyo kusiza udokotela wakho ukuhlela indlela yokwelapha engcono kakhulu. Umehluko omkhulu phakathi kwezinhlobo yindlela ephikisanayo ngayo isimo nokuthi yiziphi izitho ezihlaselekayo kakhulu.

Uhlobo oluvamile kakhulu yi-indolent systemic mastocytosis, eya phambili kancane futhi abantu abaningi baphila isikhathi eside sokuphila ngokuphathwa okuhle. Lolu hlobo ngokuvamile lubangela izimpawu ezingathandeki kodwa aliwulimazi kakhulu izitho zakho.

I-Smoldering systemic mastocytosis isebenza kancane kunohlobo lwe-indolent. Ungase ube nezimpawu ezibonakalayo kakhulu nokubandakanyeka kwezinye izitho, kodwa isaqhubeka kancane futhi iphendula kahle ekwelapheni.

I-Aggressive systemic mastocytosis iyinkulu futhi ingathinta ukusebenza kwezitho. Lolu hlobo lufuna ukwelashwa okukhulu kakhulu nokulandelela. Ama-mast cells kuluhlobo lolu angaphazamisa indlela izitho zakho ezisebenza ngayo kahle.

Uhlobo oluyimfihlo kakhulu futhi olukhulu kakhulu yi-mast cell leukemia, lapho isimo siphatha khona njengomdlavuza wegazi. Lolu hlobo lufuna ukwelashwa okusheshayo nokuqine kakhulu, yize kubalulekile ukwazi ukuthi lolu hlobo aluvamile kakhulu.

I-Systemic mastocytosis enesimo segazi esixhunyiwe ingase ibe khona uma une-mastocytosis kanye nesimo segazi esinye. Udokotela wakho kuzodingeka aphathe kokubili izimo ndawonye kulezi zimo.

Yini ebangela i-systemic mastocytosis?

I-Systemic mastocytosis ibangelwa izinguquko ze-genetic ezenzeka kumaseli e-bone marrow akho. Imbangela evamile kakhulu ukuguqulwa kwijini elibizwa nge-KIT, elilawula indlela ama-mast cells akhula futhi asebenza ngayo.

Lokhu kushintsha kwe-genetic kuvame ukwenzeka phakathi nokuphila kwakho kunokuba kuzuzwe kubazali bakho. Yilokho odokotela abakubiza ngokuthi “somatic mutation,” okusho ukuthi kuthuthukela ezicelisweni zomzimba wakho ngemva kokuzalwa, hhayi into ozalwa unayo.

Ukuhluka kwe-KIT gene kubangela ubuhlalu bakho bomthambo ukukhiqiza amaseli amaningi ama-mast, futhi la maseli awasebenzi kahle. Esikhundleni sokuphendula kuphela ezinhlelweni zangempela, angakhulula amakhemikhali abo ngokungafanele, okubangela izimpawu ozibona.

Nakuba izincazelo eziningi zingalitholiwe, kunezinhlobo zomndeni ezingavamile lapho isimo singadlulela emindenini. Uma unomlando womndeni we-mastocytosis, kubalulekile ukuxoxa lokhu nodokotela wakho, nakuba abantu abaningi abane-systemic mastocytosis abanawo umlando womndeni wesimo.

Abacwaningi basafunda ukuthi yini engase iqhube lokhu kushintsha kwe-genetic. Okwamanje, ayikho indlela eyaziwayo yokuvimbela ukuhluka kwe-genetic okubangela i-systemic mastocytosis ukwenzeka.

Nini kufanele ubona udokotela nge-systemic mastocytosis?

Kufanele ubona udokotela uma ubhekene nezimpawu eziphindaphindayo ezibukeka sengathi zenzeka ngaphandle kwezinqubo ezicacile, ikakhulukazi uma zihilela izinhlelo eziningi zomzimba. Abantu abaningi abane-systemic mastocytosis baqhubeka iminyaka ngaphandle kokuxilongwa okuqondile ngoba izimpawu zingaphambanyiswa nezinye izimo.

Funani ukunakekelwa kwezokwelapha uma une-flushing yesikhumba esiqhubekayo, izinkinga zokugaya ukudla ezingachazwanga, ubuhlungu lwamathambo, noma ukusabela okuvamile okufana ne-allergic. Lezi zimpawu, ikakhulukazi lapho zenzeka ndawonye, zingadinga ukuhlolwa okuqhubekayo.

Kufanele ufunani ukunakekelwa kwezokwelapha ngokushesha uma ubhekene nezimpawu ezinkulu njengokubuthakathaka ekuphemeni, ukwehla okukhulu kwegazi, ukulahlekelwa uqaphelo, noma izimpawu zokusabela okukhulu kwe-allergic. Lokhu kungabonisa ukusabela okukhulu kweselula ye-mast okudingayo ukwelashwa okusheshayo.

Uma uthola ukuthi une-systemic mastocytosis, qhubeka uxhumana njalo neqembu lakho lokunakekelwa kwezempilo. Bangakusiza ukuthi uqaphele izimpawu zokuqala futhi ulungise ukwelashwa kwakho njengoba kudingeka. Unganqikazi ukuxhumana nabo uma izimpawu zakho zishintsha noma zibe zimbi.

Kubalulekile futhi ukubona udokotela wakho ngaphambi kwanoma iyiphi inqubo yezokwelapha, ukuhlinzwa, noma umsebenzi wamahlwengwe. Abantu abane-systemic mastocytosis bangadinga izindlela ezikhethekile zokuqapha ngesikhathi salezi zinqubo ukuvimbela ukubangela ukusabela kwamaselula e-mast.

Iyini imikhakha yokusabela kwe-systemic mastocytosis?

I-Systemic mastocytosis ingathinta noma ubani, kodwa izici ezithile zingathinta amathuba akho okukhula kuleli simo. Ukuqonda le mikhakha yokusabela kungakusiza wena nodokotela wakho ukuthi niqaphele izimpawu ezingase zivele.

Ubudala budlala indima e-systemic mastocytosis, ngezigameko eziningi ezitholakala kubantu abadala abaphakathi kweminyaka engama-20 nama-40. Noma kunjalo, lesi simo singase sivele kunoma iyiphi iminyaka, kufaka phakathi izingane nabantu abadala.

Ukuba ne-cutaneous mastocytosis (i-mastocytosis yesikhumba kuphela) njengengane kungase kukhulise amathuba akho okukhula uhlobo olukhulu kamuva ekuphileni. Akuwona wonke umuntu one-mastocytosis yesikhumba sobuntwana othola isifo sesistimu, kodwa yinto odokotela abaqapha.

Kubukeka sengathi ubulili bunomthelela othile, ngamadoda amaningi kunabesifazane abatholwa be-systemic mastocytosis. Noma kunjalo, umehluko awukabi mkhulu, futhi lesi simo sithinta bobabili abesilisa nabesifazane.

Ukuba nomlando womndeni we-mastocytosis kuyisici sokusabela, nakuba lokhu kuyinto engavamile. Izimo eziningi ze-systemic mastocytosis zenzeka ngokungahleliwe ngaphandle komlando womndeni wesimo.

Okwamanje, abacwaningi abakaze bathole izici ezithile zemvelo noma zesitayela sokuphila ezikhulise amathuba akho okukhula i-systemic mastocytosis. Ukuguqulwa kwe-genetic okubangela lesi simo kubonakala kwenzeka ngokungahleliwe ezimweni eziningi.

Ziyini izinhlanganisela ezingase zivele ze-systemic mastocytosis?

Nakuba abantu abaningi abane-systemic mastocytosis bephila impilo egcwele, esebenzayo ngokuphathwa okuqondile, kubalulekile ukuqonda izinhlungu ezingase zenzeke ukuze ukwazi ukusebenzisana neqembu lakho lokunakekelwa kwezempilo ukuze uzivikele noma uziphathe ngokuphumelelayo.

Izinhlungu ezivame kakhulu zihilela amathambo akho futhi zingafaka i-osteoporosis noma ukweqa kwamathhambo. Lokhu kwenzeka ngoba amaseli e-mast angaphazamisa ukusebenza okujwayelekile kwamathhambo, okwenza amathambo akho abe buthakathaka ngokuhamba kwesikhathi. Ukulandelela njalo ubukhulu bamathhambo nokuphathwa okuqondile kungasiza ukuvimbela izinkinga ezinkulu zamathhambo.

Izinhlungu zokugaya ukudla zingase zenzeke uma amaseli e-mast ethonya isisu nezimpondo zakho. Ungase uthole izihlamba, izinkinga zokungagayi kahle, noma izinkinga zokugaya ukudla ezingapheli. Lezi zinkinga ngokuvamile zingaphathwa ngemithi nokwenza izinguquko ekudleni.

Ukuphazamiseka okukhulu okungokwe-alerjikhi, okuthiwa yi-anaphylaxis, kubonisa enye yezinkinga ezinkulu kakhulu. Lezi zinkinga zingaba yingozi ekuphileni futhi zingase zenzeke ngaphandle noma ngezizathu ezicacile. Udokotela wakho cishe uzokunika imithi yokuphuthuma kanye nokukufundisa ukuthi ungazibona kanjani futhi uphendule kanjani kulezi zinkinga.

Izinhlungu ezihlobene negazi zingafaka i-anemia, ukuphuza igazi okungajwayelekile, noma ubukhulu be-spleen. Lokhu kwenzeka uma amaseli e-mast ephazamisa ukukhiqizwa noma ukusebenza kweziseli zegazi okujwayelekile. Izivivinyo zegazi eziqondile zisiza udokotela wakho ukuba alandelele lezi zinkinga.

Kwezinye izikhathi, abantu abanezinhlobo ezinamandla ze-systemic mastocytosis bangase bathuthukise ukonakala kwamalungu okuthonya isibindi, inhliziyo, noma amanye amalungu. Kungakho ukulandelela njalo nokuphathwa okuqondile kubaluleke kakhulu ekuphatheni isimo sakho ngokuphumelelayo.

Izinhlungu ezingokwengqondo njengokukhathazeka noma ukucindezeleka zingase zithuthuke, ikakhulu uma izimpawu kunzima ukuzilawula. Ukuphila nesimo esingapheli kungaba inselele, futhi kubalulekile ukubhekana nezici zempilo yakho zomzimba nezingokwengqondo.

I-systemic mastocytosis ihlonishwa kanjani?

Ukuxilongwa kwe-mastocytosis yesistimu kudinga ukuhlolwa okuningi ngoba izimpawu zingafana nezinye izimo eziningi. Udokotela wakho uzoqala ngomlando wezokwelapha ophelele kanye nokuhlolwa komzimba, egxila ezimpawu zakho nasesikhathini lapho zenzeka khona.

Izivivinyo zegazi ngokuvamile yisinyathelo sokuqala ekuxilongweni. Udokotela wakho uzoqapha amazinga akho e-tryptase, okuyinto ephuma kumaseli e-mast. Amazinga aphezulu e-tryptase angaphakamisa i-mastocytosis, nakuba akuwona wonke umuntu onalesimo onemazinga aphezulu.

I-biopsy yomgogodla wamathambo idingeka ukuqinisekisa ukuxilongwa. Ngalesi senzo, udokotela wakho uthatha isampula encane yomgogodla wamathambo, ngokuvamile emathanjeni akho, ukubuka amaseli e-mast angajwayelekile ngaphansi komkhiqizo. Lolu viwo luphinde luvumele ukuhlolwa kwe-genetic ukubuka ukuguqulwa kwe-KIT.

Ukuhlolwa okwengeziwe kungafaka i-CT scans noma ezinye izifundo zokwenza izithombe ukuhlola ukubandakanyeka kwezinye izitho. Udokotela wakho angase futhi enze ukuhlolwa okukhethekile ukulinganisa ukuthi amaseli akho e-mast aphendula kanjani ezinhlobonhlobo ezithile.

Inqubo yokuxilongwa ingathatha isikhathi, futhi kungadingeka ubona ochwepheshe abanjengabahlolwa beziguli noma abagciki bezifo eziphikisanayo abanokuhlangenwe nakho nge-mastocytosis. Ungadangali uma ukuxilongwa kuthatha izikhathi eziningi zokubona udokotela noma ukuhlolwa ukuze kuqinisekiswe.

Udokotela wakho uzofuna futhi ukukhipha ezinye izimo ezingabangela izimpawu ezifanayo. Lendlela ephelele iqinisekisa ukuthi uthola ukuxilongwa okulungile kanye nokwelashwa okulungile kakhulu esimweni sakho esithile.

Iyini impilo ye-mastocytosis yesistimu?

Ukwelashwa kwe-mastocytosis yesistimu kugxila ekulawuleni izimpawu zakho nokuvimbela izinkinga. Njengoba akukho ukwelashwa okuphelele kwizinhlobo eziningi zalesimo, umgomo ukukusiza uphile ukhululekile futhi ngokujwayelekile ngangokunokwenzeka.

Imithi ye-antihistamine ivame ukuba yindlela yokuqala yokwelapha futhi ingasiza ukulawula izimpawu eziningi ezifana nokukhahlela, ukuqhuma, nezingqinamba zokugaya. Udokotela wakho angase abele imithi ye-antihistamine ye-H1 ne-H2, evikela izinhlobo ezahlukene zamaseseli e-histamine emzimbeni wakho.

Abaqinisa amaseli e-mast njenge-cromolyn sodium bangasiza ukuvimbela amaseli akho e-mast ekukhululeni amakhemikhali abo ngokungafanele. Le mithi iyasiza ikakhulukazi ezimpawu zokugaya futhi ingathengwa ngomlomo noma isetshenziswe njenge-nasal spray.

Ngezingqinamba ezihlobene nethambo, udokotela wakho angase acebise imithi eqinisa amathambo akho, njenge-bisphosphonates noma izithasiselo ze-vitamin D. Ukulandelela njalo ubukhulu bamathambo kusiza ukuqondisa le mithi.

Uma ungosongo lwemiphumela emibi eqinile ye-allergic, udokotela wakho uzokunikeza imithi yokuphuthuma njenge-epinephrine auto-injectors. Uzofunda futhi ukuthi ungazibona kanjani izimpawu zexwayiso zomphumela omubi futhi nini kufanele usebenzise le mithi.

Ngezinhlobo ezinamandla ze-systemic mastocytosis, imithi ehloselwe njenge-tyrosine kinase inhibitors ingase icelwe. Le mithi emisha ihlose ngokuqondile ukuguqulwa kwe-genetic okubangela isimo futhi ingase ibe yiphumelela kakhulu kwabanye abantu.

Ezimweni ezingavamile zesifo esinamandla kakhulu, ukwelashwa njenge-chemotherapy noma ukutshalwa kwamaseli e-stem kungase kucabangelwe. Lokhu ukwelashwa okuqine kumiselwe ezinhlotsheni ezinkulu kakhulu zesimo.

Indlela yokuphatha i-systemic mastocytosis ekhaya?

Ukuphatha i-systemic mastocytosis ekhaya kuhilela ukufunda ukuhlonza nokuqeda izinto ezibangela isimo sakho ngenkathi ugcina indlela yokuphila enempilo esekela impilo yakho yonke. Abantu abaningi bathola ukuthi ngokunakekela okuhle, banganciphisa kakhulu izimpawu zabo.

Ukugcina idayari yezimpawu kungasiza kakhulu ekutholeni izindlela kanye nezinto ezibangela izimpawu. Bhala lokho okudlayo, imisebenzi yakho, amazinga engcindezi, nanoma yiziphi izimpawu ozibona. Ulwazi olufana nalolu lusiza wena nodokotela wakho ukuqonda ukuthi yini engase ibe yimbangela yokwanda kwezimpawu.

Ukushintsha ukudla kuvame ukuba nomthelela omkhulu ekuphatheni izimpawu. Abantu abaningi abane-mastocytosis bayazuza ngokugwema ukudla okune-histamine eningi, njengochisi oluqadile, ukudla okumenywe, iwayini, nenyama ethile eyenziwe. Noma kunjalo, izinto ezibangela izimpawu zihlukahluka kumuntu ngamunye.

Ukuphatha ingcindezi kubalulekile ngoba ingcindezi yengqondo ingabangela ukusebenza kwamasero e-mast. Cabanga ngokufaka amasu okuphumula njengokuphefumula okujulile, ukucamngca, i-yoga ebushelelezi, noma noma yikuphi okunye okusebenza kahle kuwe.

Ukushintsha okukhulu kokushisa kungabangela izimpawu kubantu abaningi, ngakho ukugqoka izigqoko eziningi nokugwema izindawo ezishisayo noma ezibandayo uma kungenzeka kungasiza. Abanye abantu bathola ukuthi ukushintsha okuncane kokushisa kuyatholakala kunokushintsha okusheshayo.

Hlala uthwala imithi yakho yokuphuthuma uma unayo, futhi uqinisekise ukuthi amalungu omndeni noma abangane abaseduze bayazi ukuthi bangakusiza kanjani uma kwenzeka impendulo enzima. Cabanga ngokugqoka ibhulukwe le-alamu yezokwelapha elibonisa isimo sakho.

Gcina uxhumano oluhle neqembu lakho lokunakekelwa kwezempilo futhi ungangabazi ukuxhumana nabo uma ubona ukushintsha ezimpawu zakho noma uma amasu akho okulawula awasebenzi kahle.

Kufanele ulungiselele kanjani i-aphoyintimenti yakho nodokotela?

Ukulungiselela i-aphoyintimenti yakho nodokotela kungasiza ukuqinisekisa ukuthi uthola okuningi kakhulu ekuhambeleni kwakho futhi unikeze iqembu lakho lokunakekelwa kwezempilo ngolwazi olulidingekayo ukuze likusize ngokuphumelelayo. Ukulungiselela okuhle kubaluleke kakhulu ngesimo esiyinkimbinkimbi njenge-systemic mastocytosis.

Letha uhlu oluqondile lwazo zonke izimpawu zakho, kuhlanganise nokuthi zaqala nini, zingakanani kanye nokuthi yini ebonakala izibangela. Faka ngisho nezimpawu ezingase zibonakale zingena lutho, njengoba i-mastocytosis ingathinta izinhlelo eziningi zomzimba ngezindlela ezingabonakali ngaso sonke isikhathi.

Hlela uhlu oluphelele lwazo zonke izidakamizwa ozithathayo, kuhlanganise nezinye izidakamizwa, izidakamizwa ezingaphezu kokuthengiswa, izongezelelo, kanye nezinongo zomhlanga. Ezinye izidakamizwa zingase zihlangane nokwelashwa kwe-mastocytosis noma zibangele izimpawu.

Lungiselela uhlu lwemibuzo ofuna ukuyibuza udokotela wakho. Zibhale phansi ngaphambi kokuba ungakhohlwa ngesikhathi sokuqokwa. Faka imibuzo mayelana nezinketho zokwelapha, ukuguqulwa kwesitayela sokuphila, izimpawu zokuqapha, nokuthi nini kufanele ufuna ukunakekelwa okuphaphandayo.

Uma ubona udokotela omusha, buthana amarekhodi akho ezempilo, kuhlanganise nanoma yimiphi imiphumela yokuhlola yangaphambili, imibiko ye-biopsy, noma izifundo zokufanekisa ezihlobene nesimo sakho. Lokhu kusiza umhlinzeki wakho wezempilo omusha ukuthi aqonde ngokushesha umlando wakho wezokwelapha.

Cabanga ukuthi ulethe ilungu lomndeni othembekile noma umngani ekubeni kwakho. Bangakusiza ukuba ukhumbule ulwazi olubalulekile oluxoxwe ngesikhathi sokuvakasha futhi banikeze ukwesekwa ngokomzwelo, ikakhulukazi uma uxoxa ngokuguqulwa kokwelapha noma izimpawu ezintsha.

Cabanga ngezinjongo zakho zokubonisana. Ingabe uyathemba ukulungisa ukwelashwa kwakho kwamanje, uxoxe ngezimpawu ezintsha, noma ufunde ngokuguqulwa kwesitayela sokuphila? Ukuba nezinjongo ezicacile kusiza ukugcina ingxoxo igxile futhi ibe nomphumela.

Iyini into ebaluleke kakhulu mayelana ne-mastocytosis yesistimu?

Into ebaluleke kakhulu okumele uyiqonde mayelana ne-mastocytosis yesistimu ukuthi nakuba kuyisimo esinzima esidinga ukunakekelwa okuqhubekayo kwezokwelapha, abantu abaningi abanesimo bangaphila impilo egcwele, esebenzayo ngokuphathwa okuqondile nokwelashwa. Ukuxilongwa kwasekuqaleni nokukhathalela okufanele kwenza umehluko omkhulu ezingeni lakho lokuphila.

Lesi simo sihlukile kakhulu kubantu, okusho ukuthi isipiliyoni sakho singase sihluke kakhulu kunesomunye umuntu onalesi simo esifanayo. Ukusebenzisana eduze neqembu lakho lokunakekelwa kwezempilo ukuze lenze uhlelo lokwelashwa oluqondene nawe kubalulekile ekulawuleni izimpawu zakho nezidingo zakho ezithile.

Ukufunda ukuqaphela izinto ezibangela izimpawu zakho kanye nezimpawu zexwayiso kukwenza ukwazi ukuthatha indima ephambili ekulawuleni isimo sakho. Abantu abaningi bathola ukuthi ngokuhamba kwesikhathi nempilo, baba namakhono kakhulu ekugwemeni ukuqhuma kwezimpawu nokulawula izimpawu uma zivele.

Khumbula ukuthi ucwaningo lwe-systemic mastocytosis luqhubeka, futhi izindlela ezintsha zokwelapha ziqhubeka zithuthukiswa. Ukuxhumana neqembu lakho lokunakekelwa kwezempilo kanye nemiphakathi yokusekela i-mastocytosis kungakusiza uhlale unolwazi mayelana nokuthuthuka ekunakekelweni.

Okubaluleke kakhulu, ungavumeli lesi simo sichaze impilo yakho yonke. Nakuba uzodinga ukwenza izinguquko ezithile futhi uhlale ulinda impilo yakho, abantu abaningi abane-systemic mastocytosis baqhubeka bephishekela imigomo yabo, bagcine ubuhlobo babo, futhi bajabulele impilo ngokugcwele.

Imibuzo evame ukubuzwa mayelana ne-systemic mastocytosis

Ingabe i-systemic mastocytosis uhlobo lomdlavuza?

I-Systemic mastocytosis ihlukaniswe njengesiyaluyalu legazi, futhi ezinye izinhlobo zingasebenza njengomdlavuza, kodwa izinhlobo eziningi azibhekwa njengomdlavuza wangempela. Uhlobo oluthambile, oluyinto evamile, ngokuvamile alunciphisi isikhathi sokuphila futhi luphathwa njengesimo esingapheli. Izinhlobo ezinamandla kakhulu kuphela, njenge-mast cell leukemia, ezisebenza njengomdlavuza wesiko futhi zidinga ukwelashwa okufana nomdlavuza.

Ingabe i-systemic mastocytosis ingelashwa?

Okwamanje, ayikho impumuzo yizinhlobo eziningi ze-systemic mastocytosis, kodwa isimo singaphathwa kahle kakhulu ngokwelashwa okufanele. Abantu abaningi baphila isikhathi eside sokuphila ngokujwayelekile ngekhwalithi enhle yokuphila ngokulawulwa kwezimpawu nokulandelela njalo. Ucwaningo mayelana nokwelashwa okusha, kufaka phakathi ukwelashwa okuqondiswe, luyaqhubeka lukhombisa imiphumela ethembisayo yokuthola imiphumela emihle yesikhathi eside.

Ingabe abantwana bami bayozuza i-systemic mastocytosis kimi?

Iningi lezimpawu ze-systemic mastocytosis alizuziwe, ngakho-ke abantwana bakho abanamathuba okuthola isimo ngoba nje unalo. Izimo eziningi zivela ekuhlanganiseni kwe-genetic okuvela phakathi nokuphila komuntu kunokudluliselwa kubazali. Noma kunjalo, kunezinhlobo zomndeni ezingavamile, ngakho-ke kubalulekile ukuxoxa ngomlando womndeni wakho nodokotela wakho futhi mhlawumbe umxhumanisi we-genetic.

Ngingaba ne mimango evamile nge-systemic mastocytosis?

Abesifazane abaningi abane-systemic mastocytosis banemimango ephumelelayo, kodwa kudinga ukuhlelwa ngokucophelela nokubhekwa yiqembu lakho lokunakekelwa kwezempilo. Ukukhulelwa ngezinye izikhathi kungabangela izimpawu, futhi amanye amaphilisi angadingeka alungiswe. Udokotela wakho we-obstetrician kanye nochwepheshe we-mastocytosis kufanele basebenzisane ukuze bakhe uhlelo lokwelashwa oluvikelekile kokubili wena nengane yakho phakathi kokukhulelwa nokubeletha.

Ngingachaza kanjani isimo sami emindenini nabangane?

Ungachaza ukuthi i-systemic mastocytosis yisimo lapho i-immune system yakho ikhiqiza khona amaseli amaningi athile abizwa ngama-mast cells, angabangela ukusabela okufana ne-allergic emzimbeni wakho. Xelela ukuthi ngenkathi izimpawu zingabikezelwa futhi ngezinye izikhathi zinzima, isimo singaphathwa ngenakekelo efanele. Kuwusizo ukufundisa umndeni oseduze nabangane mayelana nezinhlungu zakho eziphuthumayo kanye nezibonakaliso zezexwayiso ukuze bakwazi ukukusekela uma kudingeka.