Agammaglobulinemia Ex-Ehlanganiswe Ne-X
Uhlolojikelele
I-X-linked agammaglobulinemia (a-gam-uh-glob-u-lih-NEE-me-uh), ebizwa nangokuthi i-XLA, yisifo sesistimu yomzimba esidluliselwa emindenini, esibizwa ngokuthi lifa. I-XLA yenza kube nzima ukulwa nokutheleleka. Abantu abane-XLA bangatheleleka endlebeni yangaphakathi, amasayinasi, umgudu womoya, igazi namalungu angaphakathi. I-XLA cishe ihlala ithinta amadoda. Kodwa abesifazane bangaba nayo i-gene ehambisana naleli gciwane. Abantu abaningi abane-XLA baqaphelwa besebengabantwana noma besebancane, ngemuva kokuba sebehlushwe yizifo eziningi. Abanye abantu abaqaphelwa kuze kube yilapho sebekhulu.
Izimpawu
Izingane eziningi ezine-XLA zibonakala zinempilo ezinyangeni ezimbalwa zokuqala. Zivikela amaprotheni abizwa ngama-antibodies azitholile kumama azo ngaphambi kokuzalwa. Uma la ma-antibodies eshiya imizimba yazo, izingane ziqala ukuthola ukutheleleka okubangelwa yibhaktheriya okuphindaphindayo. Ukutheleleka kungaba yingozi eyingozi. Ukutheleleka kungase kuhilele izindlebe, amaphaphu, amasayinasi nesikhumba. Izingane ezingamadodana ezizalwa zine-XLA zina: Amatonsil amancane kakhulu. Ama-lymph nodes amancane noma engekho.
Izimbangela
I-X-linked agammaglobulinemia ibangelwa yishintsho ku-gene. Abantu abaneli leli gciwane abakwazi ukukhiqiza amaprotheni abizwa ngokuthi amasu okumelana nokutheleleka. Cishe amaphesenti angu-40 abantu abaneli leli gciwane banezihlobo ezinaleli gciwane.
Izingqinamba
Abantu abane-XLA bangaphila impilo evamile kakhulu. Kufanele bazame ukuhlanganyela emisebenzini evamile yobudala babo. Kodwa ukutheleleka okuphindaphindayo okuxhumene ne-XLA cishe kuzodinga ukubhekwa nokwelashwa okucophelelayo. Kungalimaza amangqamuzana futhi kube yingozi eyingozi. Izinhlungu ezingase zenzeke zihlanganisa: Isikhathi eside, ebizwa ngokuthi yi-chronic, isifo samathumbu. Ubungozi obukhulu bezinye izinhlobo zomdlavuza. Ukutheleleka kwe-Infectious arthritis. Ubungozi obukhulu bokuthola ukutheleleka kwesistimu yezinzwa eziyinhloko ezivela ekuhlanganiseni okuqhubekayo.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.