Yini i-Abacavir-Lamivudine-and-Zidovudine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Abacavir-lamivudine-and-zidovudine iyinhlanganisela yomuthi we-HIV osiza ukulawula igciwane emzimbeni wakho. Le pilisi eyodwa iqukethe imithi emithathu ehlukene esebenza ngokubambisana ukuvimbela i-HIV ukuthi ingaphindaphindi futhi ilimaze amasosha akho omzimba. Abantu abaningi bathola le nhlanganisela ilusizo ngoba yenza umsebenzi wabo wansuku zonke ube lula ngenkathi iphatha ngempumelelo ukutheleleka kwabo nge-HIV.

Yini i-Abacavir-Lamivudine-and-Zidovudine?

Lo muthi uyiphilisi elinethathu-kwelinye elihlanganisa i-abacavir, i-lamivudine, kanye ne-zidovudine ethebuleni elilodwa. Ngamunye wale mithi ungoweqembu elibizwa ngokuthi ama-nucleoside reverse transcriptase inhibitors, avimbela i-HIV ukuthi ingazikopishi ngaphakathi kwamaseli akho. Ukuthatha bonke abathathu ndawonye epilisi eyodwa kwenza ukwelashwa kwakho kube lula futhi kube lula kunokuthatha imithi ehlukene.

Le nhlanganisela isebenza ngokuhlasela i-HIV esigabeni esifanayo somjikelezo wayo wokuphila kodwa ngendlela ehlukile kancane. Le ndlela isiza ukuvimbela igciwane ukuthi lingamelani nokwelashwa. Udokotela wakho angase abhekisele kulolu hlobo lokwelashwa njengokwelashwa okuhlanganisiwe kwe-antiretroviral noma i-cART.

Isetshenziselwani i-Abacavir-Lamivudine-and-Zidovudine?

Lo muthi welapha ukutheleleka nge-HIV kubantu abadala kanye nezingane ezinobunzima obungamakhilogremu angama-40 (cishe amaphawundi angama-88). Isiza ukunciphisa inani le-HIV egazini lakho liye emazingeni aphansi kakhulu, okuvikela amasosha akho omzimba futhi kuvimbele izinkinga ezihlobene ne-AIDS. Umgomo uwukwenza umthwalo wakho wegciwane ungabonakali, okukuvimbela futhi ukuthi ungadluliseli i-HIV kwabanye.

Odokotela bavame ukunquma le nhlanganisela njengengxenye yohlelo oluphelele lokwelashwa kwe-HIV. Cishe uzothatha lo muthi kanye neminye imithi ye-HIV ukuze udale ukuvikela okunamandla ngokuqeda igciwane. Le ndlela isize izigidi zabantu abane-HIV ukuthi baphile impilo ende, enempilo.

Isebenza kanjani i-Abacavir-Lamivudine-and-Zidovudine?

Le mithi ehlanganisiwe isebenza ngokuvimba ikhono le-HIV lokwenza amakhophi awo ngaphakathi kwamaseli akho omzimba. Isithako ngasinye siqondisa i-enzyme efanayo ebizwa ngokuthi i-reverse transcriptase, kodwa sikwenza ngezindlela ezehlukile. Cabanga ngakho njengokuba nokhiye abathathu abahlukene emnyango owodwa - i-HIV idinga ukudlula kubo bobathathu ukuze iqhubeke nokusabalala.

Lapho i-HIV ingena emaseleni akho, izama ukuguqula izinto zayo zofuzo zibe yifomu amaseli akho angalifunda. Le mithi emithathu iphazamisa le nqubo ngokuhlinzeka ngezinto zokwakha ezingamanga ezinqabela igciwane ukuthi liqede ukuziphinda kwalo. Lokhu kuthathwa njengokwelashwa kwe-HIV okuqinile okulinganiselwe okungakwazi ukulawula ngempumelelo igciwane uma lisetshenziswa njalo.

Kufanele Ngiyithathe Kanjani I-Abacavir-Lamivudine-and-Zidovudine?

Thatha lo muthi njengoba nje udokotela wakho ekuyala, ngokuvamile kabili ngosuku ngaphandle kokudla noma ngaphandle kokudla. Ungayithatha ngamanzi, ubisi, noma ijusi - noma yini ozizwa ukhululekile ngayo. Abanye abantu bakhetha ukuyithatha ngesnakhi esilula ukuze bagweme noma yikuphi ukuphazamiseka kwesisu, nakuba lokhu kungadingeki.

Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo omuthi emzimbeni wakho. Ukusetha izikhumbuzi zocingo noma ukusebenzisa umhleli wamaphilisi kungakusiza ukuthi uhlale emgwaqeni. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nokuthi ungakwazi yini ukuhlukanisa noma ukuchoboza ithebhulethi.

Ungalokothi weqe imithamo noma uyeke ukuthatha lo muthi ngaphandle kokukhuluma nodokotela wakho kuqala. Ukugeza imithamo kungavumela i-HIV ukuthi imelane nokwelashwa, okwenza kube nzima kakhulu ukulawula ukutheleleka kwakho esikhathini esizayo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Abacavir-Lamivudine-and-Zidovudine?

Abantu abaningi abane-HIV bathatha lo muthi impilo yabo yonke njengengxenye yohlelo lwabo oluqhubekayo lokwelashwa. Ukwelashwa kwe-HIV kuvamile ukuba ukuzibophezela kwesikhathi eside ngoba igciwane lihlala emzimbeni wakho ngisho nalapho lilawulwa kahle. Ukuyeka ukwelashwa kuvumela igciwane ukuthi liphindaphinde futhi lingalimaza amasosha akho omzimba.

Udktela wakho uzoqapha ukusabela kwakho emuthini ngokuhlola igazi njalo elilinganisa ukulayishwa kwegciwane lakho kanye nenani le-CD4. Uma le nhlanganisela ethile iyeka ukusebenza ngempumelelo noma idala imiphumela emibi, udktela wakho angase akushintshele kwenye indlela yokwelapha i-HIV. Umgomo uhlala ukuthola ukwelashwa okusebenza kahle kakhulu esimweni sakho esithile.

Yini Imiphumela Eceleni ye-Abacavir-Lamivudine-and-Zidovudine?

Njengayo yonke imithi, le nhlanganisela ingadala imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe ulungiselelwe kangcono futhi wazi ukuthi ungaxhumana nini nomhlinzeki wakho wezempilo.

Imiphumela emibi ejwayelekile abantu abaningi abayitholayo ihlanganisa isicanucanu, ikhanda, ukukhathala, nobunzima bokulala. Lezi zimpawu zivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala okwelashwa.

• Isicanucanu nokucasuka kwesisu
• Ikhanda
• Ukukhathala nobuthakathaka
• Ubunzima bokulala
• Ukuqunjelwa
• Ukulahlekelwa isifiso sokudla
• Isiyezi

Le miphumela emibi ejwayelekile ivame ukulawuleka futhi ithambekele ekunciphiseni ngokuhamba kwesikhathi. Udktela wakho angase aphonse izindlela zokunciphisa ukungakhululeki ngenkathi umzimba wakho uzivumela ekwelashweni.

Imiphumela emibi ebucayi idinga ukunakekelwa kwezempilo ngokushesha, nakuba yenzeka kaningi. Okukhathazayo kakhulu ukusabela okungase kube yingozi ekuphileni komzimba ku-abacavir, okungase kwenzeke kwabanye abantu abanomaki othile wofuzo.

• Ukuphendula okukhulu komzimba okune-fever, ukuqubuka, isicanucanu, nobunzima bokuphefumula
• I-anemia ebucayi noma ukubala okuncane kwamangqamuzana amhlophe egazi
• Izinkinga zesibindi ezinokuphuzi kwesikhumba noma amehlo
• Ubuhlungu bemisipha obukhulu noma ubuthakathaka
• I-lactic acidosis (isimo esingavamile kodwa esibucayi)

Udktela wakho cishe uzokuhlola ngophawu lofuzo olwandisa ingozi yokungezwani komzimba ngaphambi kokuqala lo muthi. Uma uba nanoma yiziphi izimpawu ezinzima, xhumana nodokotela wakho ngokushesha noma funa ukwelashwa okuphuthumayo.

Obani okungafanele basebenzise i-Abacavir-Lamivudine-and-Zidovudine?

Lo muthi awulungele wonke umuntu, futhi udokotela wakho uzohlola ngokucophelela ukuthi ulungele yini. Abantu abanezimpawu ezithile zofuzo, izinkinga zesibindi, noma ezinye izimo zempilo ezithile bangase badinge ukwelashwa okuhlukile.

Akufanele usebenzise lo muthi uma ngaphambilini uke waba nokungezwani komzimba ne-abacavir, lamivudine, noma zidovudine. Udokotela wakho uzokuhlola ukuguquguquka kofuzo okubizwa nge-HLA-B*5701 ngaphambi kokuqala ukwelashwa, njengoba abantu abanalesi sikhombisi benengozi enkulu yokungezwani komzimba okunzima.

Ezinye izimo eziningi zingenza lo muthi ungafaneleki kuwe, futhi udokotela wakho uzoxoxa ngalezi ngesikhathi sokuhlolwa kwakho:

• Isifo sesibindi esinzima noma ukutheleleka nge-hepatitis B
• Izinkinga ezinzima zezinso
• Umlando we-pancreatitis
• I-anemia enzima noma ukubala kwamangqamuzana egazi okuphansi
• Ukukhulelwa (kudinga ukucatshangelwa ngokucophelela kwezingozi nezinzuzo)

Udokotela wakho uzobuyekeza umlando wakho wezokwelapha ophelele futhi angase ayale ukuhlolwa kwegazi ukuze aqinisekise ukuthi lo muthi uphephile kuwe. Ukwethembeka ngezimo zakho zempilo neminye imithi kusiza udokotela wakho ukuthi enze izinqumo ezingcono kakhulu zokwelapha.

Amagama e-Brand e-Abacavir-Lamivudine-and-Zidovudine

Lo muthi ohlanganisiwe uyatholakala ngaphansi kwegama lomkhiqizo elithi Trizivir. Inguqulo yegama lomkhiqizo iqukethe izithako ezifanayo ezisebenzayo njengenguqulo ejwayelekile, ngakho zombili zisebenza ngokulinganayo ekwelapheni ukutheleleka nge-HIV.

Ezinye izinhlelo zomshuwalense zingase zihlanganise inguqulo eyodwa kangcono kunenye, ngakho udokotela wakho noma usokhemisi angakusiza ukuthi unqume ukuthi iyiphi inketho engabizi kakhulu kuwe. Noma ngabe uthatha igama lomkhiqizo noma inguqulo ejwayelekile, into ebalulekile ukuyithatha njalo njengoba kunqunywe.

Ezinye izindlela ze-Abacavir-Lamivudine-and-Zidovudine

Ezinye izinhlanganisela zemithi ye-HIV ziyatholakala uma lokhu kwelashwa okuthile kungasebenzi kahle kuwe. Ukwelashwa kwe-HIV yesimanje kunikeza izinketho eziningi eziphumelelayo, ngakho wena nodokotela wakho ningathola indlela efanelekayo ezidingweni zakho nendlela yokuphila.

Amaphilisi ahlukile ahlanganisiwe angabandakanya amakilasi ahlukene emithi ye-HIV, njenge-integrase inhibitors noma i-protease inhibitors. Ezinye izinhlanganisela ezintsha zidinga iphilisi elilodwa ngosuku, okutholakala abanye abantu kulula. Udokotela wakho uzocabangela izici ezinjengendlela yakho yokumelana negciwane, ezinye izimo zezempilo, nezintandokazi zomuntu siqu lapho encoma ezinye izindlela.

Imithi enezithako ezilodwa nayo ingahlanganiswa ngezindlela ezahlukene ukudala izinqubo zokwelashwa eziqondene nawe. Okubalulekile ukuthola inhlanganisela elawula ngempumelelo i-HIV yakho ngenkathi inciphisa imiphumela emibi futhi ingene emsebenzini wakho wansuku zonke.

Ingabe i-Abacavir-Lamivudine-and-Zidovudine ingcono kunezinye izidakamizwa ze-HIV?

Le mithi ehlanganisiwe iyasebenza kubantu abaningi, kodwa ukuthi ingcono kunezinye izinketho kuncike esimweni sakho ngasinye. Ukwelashwa kwe-HIV kuye kwashintsha kakhulu, futhi izinhlanganisela ezintsha zingase zinikeze izinzuzo ezinjengokulinganisa kanye ngosuku noma imiphumela emibi embalwa.

Uma kuqhathaniswa neminye imithi ye-HIV entsha, le nhlanganisela idinga ukulinganisa kabili ngosuku futhi ingase ibangele imiphumela emibi eyengeziwe efana ne-anemia nesicanucanu. Kodwa-ke, inerekhodi elide lokusebenza kahle futhi lingase lithandwe ezimweni ezithile, njengokubhekana namaphethini athile okumelana nezidakamizwa.

Udktela wakho uzocabangela ukulayishwa kwakho ngegciwane, ukubalwa kwe-CD4, noma yikuphi ukumelana nemithi, ezinye izimo zempilo, kanye nezintandokazi zakho siqu lapho ekhetha ukwelashwa okungcono kakhulu kuwe. Into ebaluleke kakhulu ukuthola uhlelo ongakwazi ukuluthatha njalo esikhathini eside.

Imibuzo Evame Ukubuzwa Mayelana ne-Abacavir-Lamivudine-and-Zidovudine

Umbuzo 1. Ingabe i-Abacavir-Lamivudine-and-Zidovudine iphephile kubantu abane-hepatitis B?

Lo muthi udinga ukuqapha okukhethekile uma une-hepatitis B. Ezinye zezinto ezimbili, i-lamivudine ne-zidovudine, zingathinta igciwane le-hepatitis B, futhi ukuziyeka kungazelelwe kungase kubangele i-hepatitis B yakho ukuthi ivuthe kakhulu. Udokotela wakho uzoqapha ukusebenza kwesibindi sakho ngokucophelela futhi angase ancome ukwelashwa okwengeziwe kwe-hepatitis B ukuze akugcine uphephile.

Umbuzo 2. Kufanele ngenzeni uma ngiphuthelwa ukuthatha i-Abacavir-Lamivudine-and-Zidovudine eningi kakhulu?

Uma ngengozi uthatha okuningi kunomthamo wakho obekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha okuningi kungakhuphula ingozi yakho yemiphumela emibi, ikakhulukazi izinkinga ngamaseli egazi lakho noma isibindi. Ungalindi ukubona ukuthi uzizwa ulungile yini - kungcono ukuthola iseluleko sezokwelapha ngokushesha, noma ngabe awuzizwa izimpawu okwamanje.

Umbuzo 3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Abacavir-Lamivudine-and-Zidovudine?

Thatha umthamo ophuthelwe ngokushesha lapho ukhumbula, ngaphandle uma sekuyisikhathi somthamo wakho olandelayo ohleliwe. Uma sekuseduze nesikhathi somthamo wakho olandelayo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi.

Umbuzo 4. Ngingayeka nini ukuthatha i-Abacavir-Lamivudine-and-Zidovudine?

Akufanele uyeke ukuthatha lo muthi ngaphandle kokukhuluma nodokotela wakho kuqala. Ukwelashwa kwe-HIV kuvame ukuba yimpilo yonke ngoba igciwane lihlala emzimbeni wakho ngisho nalapho lilawulwa kahle. Udokotela wakho angase akuqhubekisele emuthini ohlukile uma lo obangela izinkinga, kodwa ukuyeka ngokuphelele ukwelashwa kwe-HIV kungavumela igciwane ukuthi liphindeke futhi lilimaze amasosha akho omzimba.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Abacavir-Lamivudine-and-Zidovudine?

Kufanele unciphise ukusetshenziswa kotshwala ngenkathi uthatha lo muthi, njengoba utshwala bungakhuphula ingozi yezinkinga zesibindi futhi bungase buphazamise indlela umzimba wakho osebenza ngayo umuthi. Uma ukhetha ukuphuza, kwenze ngokulinganisela futhi uxoxe ngokusebenzisa kwakho utshwala nodokotela wakho. Bangakusiza ukuthi uqonde ukuthi yiliphi izinga lokusetshenziswa kotshwala elingase liphephe esimweni sakho esithile.