Abemaciclib (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Verzenio
Mayelana naleli khambi
IAbemaciclib isetshenziswa kanye ne-tamoxifen noma isithunzi se-aromatase (isib. anastrozole, exemestane, letrozole) ukuze kuphathwe i-kansa yebhubesi ekuqaleni enesigaba esiphezulu se-hormone receptor (HR)-positive, HER-2 negative, node-positive, enengozi enkulu yokubuyela njengoba kunqunywe ngudokotela wakho. IAbemaciclib isetshenziswa futhi kanye nesisithunzi se-aromatase (isib. anastrozole, exemestane, letrozole) njengonyango lokuqala lwe-hormonal ukuze kuphathwe amadoda nabesifazane abangasekho ekuphileni kwabo kwesondo abanesigaba esiphezulu se-hormone receptor (HR)-positive, HER-2 negative advanced (ikansa eleqine) noma i-metastatic (ikansa esiyele) ikansa yebhubesi. Isetshenziswa futhi yodwa noma kanye ne-fulvestrant ukuze kuphathwe i-HR-positive, HER-2 negative advanced noma i-metastatic breast cancer kwabesifazane abamukele ukwelashwa kwe-hormonal noma eminye imithi yekansa engasebenzi kahle. IAbemaciclib iyingxenye yeqembu lemithi ebizwa ngokuthi yi-antineoplastics. Iphazamisa ukukhula kwamaselula ekansa, aqothulwa ekugcineni. Njengoba ukukhula kwamaselula avamile kungase kuthonyeke futhi ngumuthi, ezinye izingozi ezingafuneki ziyoba khona. Ezinye zalezi zingaba nzima futhi kufanele zibikwe kudokotela wakho. Lo muthi uyatholakala kuphela ngomyalelo wodokotela wakho. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, kubalulekile ukuqhathanisa izingozi zokusebenzisa imithi nezinzuzo ezingaba khona. Lena yinqubo ozoyenza wena nodokotela wakho. Ngale mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma iyiphi impendulo engajwayelekile noma ebangelwa ukungezwani kwalolu hlobo lomuthi noma eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokungezwani, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Akwenziwanga ucwaningo olufanele mayelana nobudlelwano phakathi nobudala nemiphumela ye-abemaciclib kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Ucwaningo olufanele oluqediwe kuze kube manje alubonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kwe-abemaciclib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokusebenzisa le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayinconywa, kodwa kungase kungenzeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi ebizwa ngokuthi i-anticancer inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokuthola le mithi, qiniseka ukuthi uyayiqonda yonke imingcipheko nezinzuzo. Kubalulekile ukusebenzisana eduze nodokotela wakho phakathi nokwelashwa kwakho. Thatha le mithi ngokuqondile njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Le mithi iza nepheshana lolwazi lwabaguli. Funda futhi ulandele lezi zinkomba ngokucophelela. Buza udokotela wakho uma unemibuzo. Gwinya ithebulethi yonke. Ungayicwili, ungayaphula, noma ungayikhononde. Thatha le mithi ngesikhathi esifanayo nsuku zonke, nokudla noma ngaphandle kokudla. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mithi. Inani lemithi elizothathwa lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi olithathayo lixhomeke emandleni emithi. Futhi, inani lemithi olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwemithi, nobude besikhathi olithatha imithi kuya ngenkinga yezokwelapha oyisebenzisela imithi. Uma uphuthelwa yidosi yale mithi, tshela idosi ophuthelwe yona bese ubuyela esimisweni sakho sokuthatha imithi. Ungawandisi amanani. Uma uhlanza ngemuva kokuthatha le mithi, ungayithathi enye idosi ngosuku olufanayo. Linda kuze kube yidosi yakho elandelayo bese uyithatha uma ubungayithatha. Gcina imithi esitsheni esivaliwe ekamelweni lokushisa, kude nokuthinta, ukufuma, nokukhanya okulungile. Gcina ungayivumeli ukuba iqhwaze. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esele iphelile noma imithi engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.