Acalabrutinib (indaba yokumunca)
Imikhiqizo etholakalayo
Calquence
Mayelana naleli khambi
I-Acalabrutinib isetshenziswa ekwelapheni i-mantle cell lymphoma (MCL) kubantu abadala abake bamukela okungenani ukwelashwa okukodwa ngaphambili kokukhuluphala kwabo. Lolu lwelapha futhi lusetshenziswa ekwelapheni i-chronic lymphocytic leukemia (CLL) noma i-small lymphocytic lymphoma (SLL). Lolu lwelapha lutholakala kuphela ngomyalo wezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, kufanele kuqhathaniswe ingozi yokuthatha imithi nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqondile noma oluhambelanayo lwalolu hlobo lomuthi noma eminye imithi. Tshela futhi ochwepheshe bezempilo uma unezinye izinhlobo zokubeletha, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenamibhalo, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ye-acalabrutinib kubantu abancane. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezithile zabantu abadala ezingalinda ukusetshenziswa kwe-acalabrutinib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile ukuthi ochwepheshe bezempilo bakwazi uma uthatha noma yimiphi imithi ehlaliswe ngezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ayinconywa. Udokotela wakho anganquma ukungakwelaphi ngale mithi noma ashintshe ezinye izidakamizwa ozithathayo. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ngokuvamile akunconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshako nanoma yimiphi imithi kungabangela ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akunconywa, kodwa kungaphepheki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshako. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi esetshenziswa ekwelapheni umdlavuza inamandla kakhulu futhi ingaba nemiphumela eminingi emibi. Ngaphambi kokusebenzisa le mithi, qiniseka ukuthi uyayiqonda yonke imingcipheko nezinzuzo. Kubalulekile ukuthi usebenzisane eduze nodokotela wakho phakathi nokwelashwa kwakho. Thatha le mithi ngokuqondile njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Le mithi iza nepheshana lolwazi lwabaguli. Funda bese ulandela lezi zinkomba ngokucophelela. Buza udokotela wakho uma unemibuzo. Gwinya ikhaphsuli noma ithebulethi yonke ngeglasi lamanzi. Ungayivuli, ungayichithe, ungayiqhube, ungayaphula, noma ungayikhinye. Ungayithatha le mithi ngokudla noma ngaphandle kokudla. Uma usebenzisa i-antacid (isib. i-calcium carbonate), yithathe okungenani amahora angu-2 ngaphambi noma ngemva kokusebenzisa ikhaphsuli. Uma usebenzisa i-blocker ye-H2 receptor (isib. i-famotidine, i-ranitidine), yithathe amahora angu-2 ngemva kokusebenzisa ikhaphsuli. Umthamo wale mithi uzobahlukile kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela imithamo yale mithi. Uma umthamo wakho uhlukile, ungawushintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi oyithatha lixhomeke emandleni emithi. Futhi, inani lemithamo oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwemithamo, nobude besikhathi oyithatha imithi kuyahlukahluka ngokuxhomekeke enkingeni yezokwelapha oyisebenzisela imithi. Uma uphuthelwa umthamo wale mithi, uwuthathe ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi somthamo wakho olandelayo, skip umthamo ophuthelwe bese ubuyela esikhathini sakho sokudla okujwayelekile. Ungawandisi imithamo. Uma uphuthelwa umthamo, futhi kungaphansi kwamahora angu-3 kusukela esikhathini sakho sokudla okujwayelekile, uwuthathe njengoba nje ubungawuthatha. Uma uphuthelwa umthamo, futhi sekudlule amahora angu-3 kusukela esikhathini sakho sokudla okujwayelekile, skip umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi sakho esijwayelekile. Ungasebenzisi imithi eyengeziwe ukuze uthole umthamo ophuthelwe. Gcina imithi esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungayivumeli ukuba iqhube. Gcina ingafinyeleleki kubantwana. Ungagcini imithi eliphelile noma imithi engasasetshenziswa. Buza ochwepheshe bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.