Yini i-Alitretinoin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Alitretinoin iyimithi ye-retinoid esetshenziswa ngaphandle esiza ukwelapha i-eczema yesandla engamahlalakhona uma ezinye izindlela zokwelapha zingasebenzi kahle ngokwanele. Lolu uhlobo lukavithamini A olusebenza ngokunciphisa ukuvuvukala nokusiza amaseli esikhumba sakho ukuthi akhule futhi achitheke ngendlela ejwayelekile.

Le mithi ingeyeqembu lemithi ebizwa ngokuthi ama-retinoids, okuyizinto ezitholakala kuvithamini A. Cabanga nge-alitretinoin njengomsizi oqondiswe ngqo ezindaweni ezinenkinga ezandleni zakho ukuze uthulise impendulo yomzimba engaphezu kwamandla ebangela izimpawu ze-eczema.

Yini i-Alitretinoin Esetshenziselwa Yona?

I-Alitretinoin yenzelwe ngqo ukwelapha i-eczema yesandla engamahlalakhona kubantu abadala. Udokotela wakho ngokuvamile uzoncoma le mithi uma i-eczema yesandla sakho isiqhubeke izinyanga noma iminyaka futhi ingazange isabele kahle kwezinye izindlela zokwelapha ezinjenge-steroids esetshenziswa ngaphandle noma ama-moisturizers.

Le mithi isebenza kahle kakhulu nge-eczema yesandla ebangela izindawo eziqinile, ezinamaqweqwe, imifantu ebuhlungu, nokuluma okuqhubekayo. Isebenza ikakhulukazi uma i-eczema ithinta ikhono lakho lokusebenzisa izandla zakho emisebenzini yansuku zonke efana nomsebenzi noma imisebenzi yasekhaya.

Ngezinye izikhathi odokotela bangase bacabange ukusebenzisa i-alitretinoin kwezinye izinhlobo ze-eczema ezinzima, kodwa i-eczema yesandla ihlala iyona esetshenziswa kakhulu futhi efundwe kahle. Le mithi ikhombise imiphumela emihle ezifundweni zemitholampilo kubantu abane-eczema yesandla ethinta kakhulu izinga lempilo yabo.

Isebenza Kanjani i-Alitretinoin?

I-Alitretinoin isebenza ngokubopha kuma-receptors athile kumaseli esikhumba sakho abizwa ngokuthi ama-retinoid receptors. Le nqubo yokubopha isiza ukulawula ukuthi amaseli esikhumba sakho akhula, ahlukanise, futhi achitheke kanjani, okunganciphisa izindawo eziqine, ezinamaqweqwe eziqhubekisa i-eczema yesandla esinzima.

Umuthi futhi unezindawo zokulwa nokuvuvukala, okusho ukuthi usiza ukuthulisa impendulo yomzimba engaphezu kwamandla esikhumbeni sakho. Lesi senzo esiphindwe kabili sisiza ukubhekana kokubili nezimpawu ezibonakalayo nokuvuvukala okuyisisekelo okuqhubela phambili i-eczema yesandla engapheli.

Njenge-retinoid enamandla aphakathi nendawo, i-alitretinoin inamandla kakhulu kune-retinol etholakala ngaphandle kwekhawunta kodwa ngokuvamile inobungane kunezinye izidakamizwa ze-retinoid eziqokiwe. Abantu abaningi baqala ukubona ngcono phakathi kwamasonto angu-12 kuya kwangu-24 okusetshenziswa njalo, nakuba abanye bengase baqaphele izinguquko ngokushesha.

Ngingayithatha kanjani i-Alitretinoin?

Kufanele usebenzise i-alitretinoin gel ngqo ezindaweni ezithintekile zezandla zakho kanye ngosuku, okungcono kusihlwa. Qala ngezandla ezihlanzekile, ezomile bese ufaka ungqimba oluncane lwe-gel kuphela ezindaweni ezinama-eczema, ugweme isikhumba esinempilo uma kungenzeka.

Ngemva kokusebenzisa umuthi, geza izandla zakho kahle ukuze ususe noma iyiphi i-gel engaphezulu ezintendeni zakho nakumunwe wakho. Lokhu kusiza ukuvimbela ukudlulisela ngengozi umuthi kwezinye izingxenye zomzimba wakho, ikakhulu ubuso bakho noma amehlo akho.

Akudingeki ukuthi uthathe i-alitretinoin nokudla njengoba isetshenziswa ngaphandle kunokuthathwa ngomlomo. Nokho, kungcono ukuyisebenzisa uma ungeke ugeze izandla zakho njalo, yingakho ukusetshenziswa kusihlwa kusebenza kahle kubantu abaningi.

Linda okungenani imizuzu eyi-15 ngemva kokusebenzisa i-gel ngaphambi kokusebenzisa ukhilimu wesandla noma i-moisturizer. Lokhu kunika umuthi isikhathi sokumuncwa kahle esikhumbeni sakho.

Ngingayithatha isikhathi esingakanani i-Alitretinoin?

Abantu abaningi basebenzisa i-alitretinoin amasonto angu-12 kuya kwangu-24 ukuze babone ukuthuthuka okukhulu ku-eczema yabo yesandla. Udokotela wakho ngokuvamile uzokwenza ukuthi uyizame okungenani amasonto angu-12 ngaphambi kokunquma ukuthi isebenza kahle ngokwanele ukuze iqhubeke.

Uma i-eczema yesandla sakho ithuthuka kakhulu ngalesi sikhathi, udokotela wakho angase ancome ukuqhubeka nokwelashwa kuze kufike kumaviki angu-24 esewonke. Abanye abantu bangase badinge izikhathi zokwelashwa ezinde, ikakhulu uma i-eczema yabo inzima kakhulu noma isikhathi eside.

Ngemuva kwenkambo yakho yokuqala yokwelashwa, udokotela wakho uzohlola ukuthi ngabe udinga yini ukwelashwa okuqhubekayo. Abanye abantu bangayeka ukusebenzisa i-alitretinoin uma i-eczema yabo isusiwe, kanti abanye bangase badinge izifundo zokwelashwa ngezikhathi ezithile ukuvimbela ukuqubuka.

Yiziphi Imiphumela Eceleni ye-Alitretinoin?

Njengayo yonke imithi, i-alitretinoin ingabangela imiphumela emibi, yize abantu abaningi beyibekezelela kahle uma isetshenziswa njengoba kuqondisiwe. Imiphumela emibi ejwayelekile ivela endaweni yokufaka isicelo futhi ivame ukuba mnene kuya esimweni esiphakathi nendawo.

Nansi imiphumela emibi ongase uyithole, iqala ngaleyo ejwayelekile kakhulu:

• Ukuvuvukala kwesikhumba, ukubomvu, noma ukusha endaweni yokufaka isicelo
• Isikhumba esomile noma ukuxebuka ezindaweni eziphathwayo
• Ukuluma noma ukuzwa ukugwaza uma kuqala ukusetshenziswa
• Ukuzwela okukhulu elangeni ezindaweni eziphathwayo
• Ubumnyama besikhashana noma ukukhanya kwesikhumba

Lezi zimpendulo zesikhumba zendawo zivame ukuthuthuka njengoba isikhumba sakho sizivumela emuthini emasontweni ambalwa okuqala okusetshenziswa. Abantu abaningi bathola le miphumela iphathwa futhi yesikhashana.

Imiphumela emibi engajwayelekile kodwa ebucayi ingabandakanya ukuvuvukala kwesikhumba okukhulu, ukusabela komzimba, noma ukwanda kwezimpawu zakho ze-eczema. Uma uhlangabezana nokusha okukhulu, ukuvuvukala, noma izimpawu zokusabela komzimba njengezinduna noma ubunzima bokuphefumula, xhumana nodokotela wakho ngokushesha.

Imiphumela emibi engavamile kodwa ebalulekile ifaka phakathi izinguquko ezinkulu ekubunjweni kwesikhumba noma izimpawu zokutheleleka kwesikhumba ezindaweni eziphathwayo. Ngenkathi lokhu kungavamile, kudinga ukunakekelwa kwezokwelapha okusheshayo uma kwenzeka.

Ubani Ongafanele Athathwe I-Alitretinoin?

I-Alitretinoin ayifanele wonke umuntu, futhi izimo ezithile ziyenza ingaphephile noma ingasebenzi kahle. Udokotela wakho uzobukeza umlando wakho wezokwelapha ngokucophelela ngaphambi kokukuyalela lo muthi.

Akufanele usebenzise i-alitretinoin uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa. Ama-Retinoids angabangela ukukhubazeka okukhulu kokuzalwa, ngakho-ke ukuhlela inzalo okuthembekile kubalulekile kwabesifazane abaneminyaka yokuzala abasebenzisa lo muthi.

Abantu abanokungezwani komzimba okwaziwayo kuma-retinoids noma yiziphi izithako ku-alitretinoin gel kufanele bagweme lo muthi. Uma uke waba nokusabela okukhulu kwezinye izinto ezitholakala kuvithamini A, yazisa udokotela wakho ngaphambi kokuqala ukwelashwa.

Labo abanezimo ezithile zesikhumba njengokusha kwelanga okukhulu, i-eczema herpeticum, noma izifo zesikhumba ezisebenzayo endaweni yokwelashwa kufanele balinde kuze kube yilapho lezi zimo zixazululeka ngaphambi kokusebenzisa i-alitretinoin.

Amagama Omkhiqizo we-Alitretinoin

I-Alitretinoin itholakala ngaphansi kwegama lomkhiqizo elithi Toctino emazweni amaningi, nakuba ukutholakala kwayo kuhluka ngokuya ngendawo. Kwezinye izindawo, ingase itholakale ngaphansi kwamanye amagama omkhiqizo noma njengokwakheka okujwayelekile.

Umthwebuli wakho wemithi angakusiza ukuthi uthole umkhiqizo othile noma inguqulo ejwayelekile etholakala endaweni okuyo. Isithako esisebenzayo sihlala singashintshi ngaphandle kwegama lomkhiqizo, kodwa izithako ezingasebenzi zingahluka kancane phakathi kwabakhiqizi.

Ezinye izindlela ze-Alitretinoin

Uma i-alitretinoin ingasebenzi kahle kuwe noma ibangela imiphumela engemihle, kukhona izindlela eziningana zokwelapha ezinye ze-eczema yesandla esibi. Udokotela wakho angakusiza ukuthi uhlole lezi zinketho ngokusekelwe esimweni sakho esithile.

Ezinye izindlela zokwelapha zihlanganisa ama-corticosteroids anamandla afana ne-clobetasol, ama-calcineurin inhibitors afana ne-tacrolimus noma i-pimecrolimus, kanye nokwelashwa okusha okufana nama-topical JAK inhibitors. Ngamunye unamandla ahlukene nemiphumela engaba khona.

Ezimweni ezinzima, ukwelashwa kwesistimu njengama-corticosteroids omlomo, i-methotrexate, noma i-cyclosporine kungase kucatshangelwe. I-Phototherapy esebenzisa ukukhanya kwe-UV nayo ingasebenza kwabanye abantu abane-eczema yesandla engapheli.

Izinketho ezintsha zihlanganisa imijovo ye-dupilumab, eqondise izindlela ezithile zokuzivikela emzimbeni ezihilelekile ku-eczema. Udokotela wakho we-dermatologist angaxoxa ngokuthi yiziphi ezinye izindlela ezingase zisebenze kangcono ohlotsheni lwakho oluthile lwe-eczema yesandla.

Ingabe i-Alitretinoin Ingcono Kune-Tacrolimus?

Kokubili i-alitretinoin ne-tacrolimus ziyizindlela zokwelapha ezisebenzayo ze-eczema yesandla, kodwa zisebenza ngezindlela ezahlukene futhi zingase zifaneleke kangcono kubantu abahlukene. Ukukhetha phakathi kwazo kuncike ezimpawini zakho ezithile, umlando wezokwelapha, kanye nemigomo yokwelashwa.

I-Alitretinoin ivame ukusebenza kahle kakhulu ku-hyperkeratotic (eshubile, enesikali) i-eczema yesandla, kuyilapho i-tacrolimus ivame ukusebenza kangcono ezinhlotsheni ezivuthayo ezinobubomvu nokuvuvukala okwengeziwe. Abanye abantu basabela kangcono emuthini owodwa kunomunye.

I-Tacrolimus ingasetshenziswa isikhathi eside futhi ayinazo izingozi ezifanayo zokukhulelwa njenge-alitretinoin. Kodwa-ke, i-alitretinoin ingahlinzeka ngentuthuko enkulu ezimweni ezinzima ezingazange zisabele kwezinye izindlela zokwelapha.

Udokotela wakho uzocabangela izinto ezinjengobudala bakho, izinhlelo zokukhulelwa, ubunzima bezimpawu, kanye nokusabela kokwelashwa kwangaphambilini lapho enquma phakathi kwalezi zinketho. Ngezinye izikhathi, bangase batusa ukuzama eyodwa kuqala bese beshintsha uma kudingeka.

Imibuzo Evame Ukubuzwa Nge-Alitretinoin

Ingabe i-Alitretinoin Iphephile Ku-Diabetes?

Yebo, i-alitretinoin ngokuvamile iphephile kubantu abanesifo sikashukela ngoba isetshenziswa ngaphandle futhi ayithinti ngokuphawulekayo amazinga kashukela egazini. Kodwa-ke, abantu abanesifo sikashukela bangase babe nokuphola kwamanxeba okuhamba kancane kanye nengozi eyengeziwe yokutheleleka.

Uma unesifo sikashukela, qaphela ngokukhethekile noma yikuphi ukusikwa noma imifantu ezandleni zakho ngenkathi usebenzisa i-alitretinoin. Qapha izindawo eziphathwayo ukuze ubone izimpawu zokutheleleka futhi ulawule kahle ushukela wakho wegazi ukuze usekele ukuphola.

Kufanele ngenzeni uma ngisebenzisa i-Alitretinoin eningi ngengozi?

Uma ufaka i-alitretinoin gel eningi, geza ngobumnene okweqile ngensipho namanzi amancane. Ukusebenzisa okuningi kunokunconyiwe ngeke kwenze umuthi usebenze kangcono futhi kungase kwandise ingozi yakho yokucasuka kwesikhumba.

Ungakhathazeki uma lokhu kwenzeka ngezikhathi ezithile, kodwa zama ukunamathela ekufakweni kwesendlalelo esincane udokotela wakho akutuse. Uma uzwa ukucasuka okukhulu ngemuva kokusebenzisa okuningi, xhumana nomhlinzeki wakho wezempilo ukuze uthole isiqondiso.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Alitretinoin?

Uma ukhohlwa ukufaka i-alitretinoin, vele uyifake ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuyisikhathi esicishe sibe sesikhathi somthamo wakho olandelayo. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungafaki i-gel eyengeziwe ukuze ubuyisele umthamo ophuthelwe, ngoba lokhu kungandisa ukucasuka ngaphandle kokuthuthukisa ukusebenza kahle. Ukuqina kubalulekile, ngakho zama ukuyifaka ngesikhathi esifanayo nsuku zonke ukuze usize ukukhumbula.

Ngingayeka nini ukuthatha i-Alitretinoin?

Kufanele uyeke i-alitretinoin kuphela ngemuva kokuxoxa ngayo nodokotela wakho, ngisho noma izimpawu zakho zithuthuka kakhulu. Ukuyeka ngaphambi kwesikhathi kungaholela ekubuyeleni kwezimpawu zakho ze-eczema yesandla.

Izifundo eziningi zokwelapha zihlala amasonto ayi-12 kuya kwangama-24, futhi udokotela wakho uzohlola inqubekela phambili yakho ngezikhathi ezithile. Bazokusiza ukuthi unqume isikhathi esifanele sokuyeka ngokuya ngokuthi isikhumba sakho siphendule kahle kangakanani kanye nezici zakho eziyingozi.

Ngingasebenzisa i-Moisturizer ngenkathi ngithatha i-Alitretinoin?

Yebo, unga futhi kufanele usebenzise i-moisturizer ngenkathi welapha nge-alitretinoin, kodwa isikhathi sibalulekile. Faka i-alitretinoin gel kuqala, linda imizuzu engaba ngu-15 ukuze imunceke, bese ufaka i-moisturizer yakho.

Khetha izinto ezithambile, ezingenamvuthwandaba zokuthambisa isikhumba ezingeke zicasule isikhumba sakho esivele sizwelana. Izinto ezinhle zokuthambisa izandla zingasiza ngempela ukunciphisa ukoma nokucasuka okuthile okungenzeka kubangelwe yi-alitretinoin, okwenza ukwelashwa kwakho kube lula.