Yini i-Alprostadil (Umgudu we-Urethral): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Alprostadil urethral suppository iyimithi kadokotela esiza amadoda ukuthi athole ukuqina lapho enokungasebenzi kahle kwe-erectile. Yiphalethi elincane olifaka ngqo emgodini wezitho zakho zangasese, lapho lincibilika khona futhi limuncwe ezicutshini ezizungezile. Le mithi iqukethe inguqulo yokwenziwa yento yemvelo umzimba wakho oyenzayo ebizwa ngokuthi i-prostaglandin E1, esiza ukwandisa ukugeleza kwegazi ukuze kwakhe ukuqina.

Yini i-Alprostadil (Umgudu we-Urethral)?

I-Alprostadil urethral suppository iyiphalethi elincane, elinosayizi welayisi eliqukethe imithi eyenzelwe ukwelapha ukungasebenzi kahle kwe-erectile. Ufaka le suppository ku-urethra yakho, okuyishubhu elithwala umchamo uphume ezithweni zakho zangasese. Imithi bese iyancibilika futhi isebenza endaweni ukukusiza ukuthi uthole ukuqina.

Lolu hlobo lwe-alprostadil luhluke emijovweni ngoba aludingi izinaliti. I-suppository yaziwa nangegama layo lomkhiqizo elithi MUSE, okusho ukuthi i-Medicated Urethral System for Erection. Ithathwa njengokwelashwa kwesibili kokungasebenzi kahle kwe-erectile, okusho ukuthi odokotela bavame ukuzama imithi yomlomo kuqala.

Imithi isebenza ngokugxila endaweni ethile oyidinga kakhulu. Ngokungafani namaphilisi ahamba emzimbeni wakho wonke, le suppository iletha imithi ngqo ezicutshini zezitho zangasese. Le ndlela eqondiwe ingaba usizo emadodeni angaphumelelanga ngemithi yomlomo noma angakwazi ukuyithatha ngenxa yezinye izimo zempilo.

Yini i-Alprostadil (Umgudu we-Urethral) Esetshenziselwa Yona?

I-Alprostadil urethral suppository isetshenziswa ikakhulukazi ukwelapha ukungasebenzi kahle kwe-erectile emadodeni. Lesi simo sisho ukuthi kunzima ukuthola noma ukugcina ukuqina okwanele kokwenza ucansi. Imithi ingasiza kungakhathaliseki ukuthi ukungasebenzi kahle kwakho kwe-erectile kubangelwa yizinkinga zomzimba, izici zengqondo, noma inhlanganisela yakho kokubili.

Odokotela bangase batusa lo muthi uma ukwelashwa ngomlomo okufana ne-sildenafil kungasebenzi kahle kuwe. Futhi kuyindlela uma ungenakukwazi ukuthatha imithi yokwelapha ukungasebenzi kahle kwesitho sobulili ngomlomo ngenxa yezimo zenhliziyo noma ukusebenzisana neminye imithi oyithathayo. Amanye amadoda akhetha le ndlela ngoba isebenza ngokushesha kunezibhebhe, ngokuvamile ngemizuzu engu-10 kuya kwengu-20.

I-suppository ingasebenza kahle emadodeni anezimo ezihlukahlukene zempilo ezingaphansi ezifaka isandla ekungasebenzi kahle kwesitho sobulili. Lokhu kufaka phakathi isifo sikashukela, umfutho wegazi ophezulu, isifo senhliziyo, noma ukulimala kwemizwa ngenxa yokuhlinzwa noma ukulimala. Kodwa-ke, kubalulekile ukuqonda ukuthi lo muthi welapha izimpawu zokungasebenzi kahle kwesitho sobulili kunokuthi ubhekane nezimbangela ezingaphansi.

Isebenza Kanjani I-Alprostadil (Umgudu We-Urethral)?

I-Alprostadil isebenza ngokulingisa into engokwemvelo umzimba wakho oyikhiqizayo ebizwa ngokuthi i-prostaglandin E1. Lo muthi ubhekwa njengomuthi oqinile ngokulinganiselwe futhi usebenza ngokukhulula imisipha ebushelelezi esithweni sakho sobulili nokwandisa imithambo yegazi. Uma le mithambo yegazi inwebeka, igazi eliningi lingangena esithweni sobulili, okwenza ukumila.

I-suppository iyancibilika ngokushesha uma ifakwe, ngokuvamile ngemizuzu embalwa. Umuthi bese umuncwa ngomugqa we-urethral bese usabalala emathanjeni azungezile okumila. Le nqubo ngokuvamile ithatha imizuzu engu-10 kuya kwengu-20 ukuze kukhiqizwe ukumila okungahlala imizuzu engu-30 kuya kwengu-60.

Ngokungafani neminye imithi yokungasebenzi kahle kwesitho sobulili esebenza emzimbeni wakho wonke, i-alprostadil isebenza endaweni esithweni sobulili. Lesi senzo esiqondiswe ngqo sisho ukuthi singasebenza ngisho noma unezinkinga zokujikeleza kwegazi kwenye indawo emzimbeni wakho. Kodwa-ke, ukusebenza komuthi kuncike ekubeni nomsebenzi othile wemithambo yegazi enempilo endaweni yesitho sobulili.

Kufanele Ngiyithathe Kanjani I-Alprostadil (Umgudu We-Urethral)?

Kufanele ufake i-alprostadil suppository ngenkathi umi futhi ngemva kokuchama. Okokuqala, geza izandla zakho kahle futhi uqinisekise ukuthi ithiphu lezitho zakho zangasese zendoda lihlanzekile. Ukuchama ngaphambi kokufaka kuyasiza ngoba inani elincane lomchamo elisele ku-urethra yakho lisiza i-suppository ukuthi incibilike kahle.

Nansi indlela yokusebenzisa i-suppository ngokuphepha nangempumelelo:

• Susa i-suppository esikhwameni se-foil ngaphambi nje kokuyisebenzisa
• Bamba izitho zakho zangasese zendoda ziqonde futhi uzelule ngobumnene ukuze uvule umgodi we-urethral
• Faka i-suppository cishe ngamasentimitha angu-2.5 ku-urethra usebenzisa i-applicator yepulasitiki
• Cindezela inkinobho ku-applicator ukuze ukhulule i-suppository
• Susa i-applicator bese uhlikihla ngobumnene izitho zakho zangasese zendoda imizuzwana engu-10 ukuze usize ukusabalalisa umuthi
• Hlala umi noma uhamba imizuzu engaba ngu-10 ukuze usize umuthi ukuthi usebenze

Akudingeki ukuthi uthathe lo muthi nokudla noma amanzi ngoba ufakwa ngqo ku-urethra. Kodwa-ke, inani elincane lomchamo ku-urethra yakho ngemva kokuchama empeleni lisiza i-suppository ukuthi incibilike futhi isebenze kangcono. Udokotela wakho uzoqala ngomthamo ophansi osebenzayo futhi angawulungisa ngokusekelwe ekutheni usebenza kahle kangakanani kuwe.

Ngingayithatha isikhathi esingakanani i-Alprostadil (Urethral Route)?

Kufanele usebenzise ama-alprostadil suppositories kuphela uma kudingeka emisebenzini yocansi, hhayi njengomuthi wansuku zonke. Amadoda amaningi awasebenzisa ngezikhathi ezithile uma ehlela ukuba nempilo yocansi. Akukho ukwelashwa okubekiwe ngoba lo muthi wenzelwe ukusetshenziswa ngezikhathi ezithile kunokwelashwa kwansuku zonke okuqhubekayo.

Udokotela wakho uzoqapha impendulo yakho emuthini ngesikhathi sokuvakasha okulandelayo. Amanye amadoda athola ukuthi umsebenzi wabo wokwakha uyathuthuka ngokuhamba kwesikhathi ngokusebenzisa ngezikhathi ezithile, kanti abanye bangase badinge ukuqhubeka bewusebenzisa isikhathi eside. Okubalulekile ukuthola ibhalansi efanele phakathi kokusebenza kahle nokuphatha noma yimaphi imiphumela emibi ongase uhlangabezane nayo.

Kubalulekile ukungasebenzisi ama-alprostadil suppositories ngaphezu kwesikhathi esiphindwe kabili emahoreni angama-24 noma ngaphezu kwesikhathi esiyisikhombisa ngesonto. Ukuwasebenzisa njalo kungakhuphula ingozi yakho yemiphumela emibi futhi kungase kuwenze angasebenzi kahle ngokuhamba kwesikhathi. Njalo landela imiyalelo ethile kadokotela wakho mayelana nokuthi ungawasebenzisa kangaki lo muthi.

Yini Imiphumela Emibi ye-Alprostadil (Urethral Route)?

Amadoda amaningi asebenzisa ama-alprostadil suppositories athola eminye imiphumela emibi, kodwa ngokuvamile imnene futhi yesikhashana. Imiphumela emibi evame kakhulu yenzeka endaweni lapho usebenzisa khona umuthi. Ukuqonda ukuthi yini ongayilindela kungakusiza uzizwe ulungile futhi uqiniseka ngokusebenzisa lokhu kwelashwa.

Imiphumela emibi evamile ongase uyithole ihlanganisa:

• Ukusha okuncane noma ubuhlungu ku-urethra ngemva kokufaka
• Ukuphuma kwegazi okuncane noma amachashaza avela ku-urethra
• Isiyezi noma ukukhathala
• Ukufudumala noma ukubomvu emilenzeni
• Ukuvuvukala okuncane ekugcineni kwelunga
• Ubuhlungu be-testicular noma ubuhlungu

Le miphumela emibi evamile ivame ukunyamalala ngemizuzu embalwa kuya ehora elilodwa ngemva kokusebenzisa i-suppository. Ukuzwa ukusha kuvame ukuba yimiphumela emibi ebonakala kakhulu, kodwa ngokuvamile iba ngaphansi kokuphazamisa njengoba ujwayela umuthi.

Imiphumela emibi engathi sína ayivamile kodwa idinga ukunakekelwa kwezokwelapha ngokushesha. Lezi zimpawu ezingavamile kodwa ezibalulekile zihlanganisa:

• Ukuqina okuhlala ngaphezu kwamahora angu-4 (priapism)
• Ubuhlungu obukhulu elungwini noma endaweni ye-pelvic
• Ukuphuma kwegazi okukhulu ku-urethra
• Ubunzima bokuchama noma ukungakwazi ngokuphelele ukuchama
• Izimpawu zokutheleleka njengomkhuhlane, ama-chills, noma ukukhishwa okungavamile
• Ukuquleka noma isiyezi esikhulu

Uma uhlangabezana nokuvuka okuhlala ngaphezu kwamahora angu-4, lokhu kuyisimo esiphuthumayo sezokwelapha esidinga ukwelashwa ngokushesha. Ukuvuka isikhathi eside kungalimaza izicubu zephenisi uma kungelashwa ngokushesha. Ngokufanayo, uma unobuhlungu obukhulu, ukuphuma kwegazi okukhulu, noma izimpawu zokutheleleka, xhumana nodokotela wakho ngokushesha.

Ubani Ongafanele Athole i-Alprostadil (Umgudu we-Urethral)?

Ama-suppositories e-Alprostadil awaphephile kuwo wonke umuntu, futhi kunezimo eziningana ezibalulekile lapho ungafanele usebenzise lo muthi. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha kanye nezimo zakho zamanje zempilo ngaphambi kokukuchazela lo muthi.

Akufanele usebenzise ama-suppositories e-alprostadil uma unezimo ezithile zezokwelapha ezingenza umuthi ube yingozi:

• I-sickle cell anemia noma ezinye izifo zegazi ezithinta ukujiya kwegazi
• I-Leukemia noma eminye imidlalo yegazi
• I-Multiple myeloma (uhlobo lomdlavuza womnkantsha wamathambo)
• Ukugoba okukhulu kwephenisi (isifo sikaPeyronie)
• Ukuqina kwe-Urethral noma ukuncipha kwe-urethra
• I-Balanitis noma ezinye izifo zephenisi

Lezi zimo zingandisa ingozi yakho yezinkinga ezinzima njengokuvuka isikhathi eside, ukuphuma kwegazi, noma ukwanda kwezinkinga zempilo ezikhona. Udokotela wakho uzobheka futhi ukuthi ngabe uthatha imithi engase ihlangane ngendlela eyingozi ne-alprostadil.

Ngaphezu kwalokho, kunezimo ezithile lapho kudingeka khona ukuqapha okwengeziwe. Amadoda anezifo zenhliziyo, umfutho wegazi ophansi, noma labo abathatha imithi yokunciphisa igazi badinga ukuqapha okukhethekile. Uma unesifo sikashukela, isifo sezinso, noma izinkinga zesibindi, udokotela wakho angase adinge ukulungisa umthamo wakho noma akuqaphele eduze.

Kubalulekile futhi ukuqaphela ukuthi lo muthi ungowamadoda kuphela futhi akufanele neze usetshenziswe ngabesifazane noma izingane. Uma wenza ucansi nomlingani ongakhulelwa, xoxa ngokuvimbela ukukhulelwa nodokotela wakho, njengoba imiphumela ye-alprostadil ekukhulelweni ingaziwa ngokugcwele.

I-Alprostadil (Urethral Route) Amagama Omkhiqizo

Igama lomkhiqizo elivame kakhulu le-alprostadil urethral suppository yi-MUSE, okusho ukuthi i-Medicated Urethral System for Erection. Leli igama lomkhiqizo ongase ulibone uma udokotela wakho ekunika lo muthi noma uma uwuthatha ekhemisi.

I-MUSE yenziwa yi-Vivus, Inc. futhi itholakala e-United States kusukela ngasekupheleni kweminyaka yawo-1990. Umuthi uza ngohlelo lokupakisha oluhlukile oluhlanganisa i-suppository kanye ne-applicator ekhethekile eyenzelwe ukwenza ukufakwa kube lula futhi kube lula.

Ngenkathi i-MUSE iyigama eliyinhloko lomkhiqizo, amanye amakhemisi angase abe nezinhlobo ezivamile ze-alprostadil suppositories. Kodwa-ke, izinhlobo ezivamile azivamile kulolu hlobo lomuthi. Njalo qiniseka ukuthi uthola umuthi oqondile odokotela bakho abaku-oda, futhi ungangeni phakathi kwemikhiqizo ehlukene noma amafomula ngaphandle kokubonisana nomhlinzeki wakho wezempilo kuqala.

Ezinye izindlela ze-Alprostadil (Urethral Route)

Uma ama-alprostadil suppositories engasebenzi kahle kuwe noma abangela imiphumela engathandeki, kunezinye izindlela zokwelapha ezisebenzayo zokungasebenzi kahle kwe-erectile. Udokotela wakho angakusiza ukuthi uhlole lezi zindlela ezingezinye ukuze uthole indlela esebenza kahle kakhulu esimweni sakho esithile.

Imithi yomlomo ivame ukuba yindlela yokuqala yokwelapha ukungasebenzi kahle kwe-erectile futhi kungase kufanele ukuzama uma ungakazami:

• I-Sildenafil (Viagra) - isebenza amahora angu-4-6
• I-Tadalafil (Cialis) - ingasebenza amahora angafika kwangu-36
• I-Vardenafil (Levitra) - ifana ne-sildenafil kodwa ingasebenza kangcono kwabanye abantu
• I-Avanafil (Stendra) - isebenza ngokushesha, ngokuvamile ngemizuzu engu-15

Uma imithi yomlomo ingafanele, kukhona ezinye izindlela zokwelapha eziqondile ezifana nama-alprostadil suppositories. Ukujova i-Alprostadil (Caverject, Edex) kuhilela ukujova umuthi ngqo ohlangothini lwesitho sangasese sendoda. Nakuba lokhu kungase kuzwakale kusabisa, amadoda amaningi athola ukujova kuphumelela kakhulu kunama-suppositories, futhi inaliti incane kakhulu.

Emadodeni akhetha izindlela ezingezona zemithi, amadivayisi okuvusa i-vacuum angasebenza ngempumelelo. Lawa madivayisi asebenzisa ukumunca okumnene ukuze adonse igazi esithweni sangasese sendoda, okwenza ukuvuka okugcinwa ngendandatho yokucinana. Nakuba kungabi ngokushesha njengemithi, lawa madivayisi asebenza kahle emibhangqwaneni eminingi.

Ezimweni lapho ezinye izindlela zokwelapha zingaphumelelanga, izitshalo zesitho sangasese sendoda zinikeza isixazululo esihlala njalo. Lawa madivayisi abekwe ngokuhlinzwa akuvumela ukuthi uthole ukuvuka noma nini lapho ufuna. Nakuba lokhu kudinga ukuhlinzwa, izitshalo zanamuhla zithembeke kakhulu futhi zinezilinganiso eziphezulu zokwaneliseka phakathi kwamadoda kanye nozakwabo.

Ingabe i-Alprostadil (Urethral Route) Ingcono Kune-Sildenafil (Viagra)?

Ukuthi ama-alprostadil suppositories angcono kune-sildenafil kuncike esimweni sakho sempilo kanye nezintandokazi zakho. Yomibili imithi iyasebenza ekungasebenzi kahle kwe-erectile, kodwa isebenza ngezindlela ezihlukene futhi inezinzuzo ezihlukene. Odokotela abaningi baqala ngemithi yomlomo efana ne-sildenafil ngoba kulula ukuyisebenzisa futhi inemiphumela emincane yendawo.

I-Sildenafil inezinzuzo ezithile ezicacile emadodeni amaningi. Ithathwa njengepilisi elilula, isebenza emadodeni amaningi anokungasebenzi kahle kwe-erectile, futhi imiphumela emibi ivame ukuba mnene futhi yesikhashana. Ungayithatha nokuthi ungayithathi ukudla, futhi ngokuvamile isebenza phakathi kwemizuzu engama-30 kuya kwengama-60. Amadoda amaningi athola imithi yomlomo ilula futhi ayihlaseli kangako kunama-suppositories.

Noma kunjalo, ama-suppository e-alprostadil nawo anezinzuzo zawo ezimweni ezithile. Asebenza ngokushesha kunesildenafil, ngokuvamile phakathi kwemizuzu eyi-10 kuya kwengama-20, futhi angasebenza kahle emadodeni angakwazi ukuthatha imithi yomlomo ngenxa yezimo zenhliziyo noma ukusebenzisana kwemithi. I-suppository futhi isebenza endaweni, ngakho-ke ingasebenza ngisho noma unezinkinga zokujikeleza kwegazi kwenye indawo emzimbeni wakho.

Ukukhetha phakathi kwale mithi kuvame ukwehla ezimweni zakho zempilo ezithile kanye nezintandokazi zakho. Uma unesifo senhliziyo futhi uthatha ama-nitrate, awukwazi ukusebenzisa i-sildenafil ngokuphepha, kodwa i-alprostadil ingase isaba yindlela. Ngakolunye uhlangothi, uma ungakhululekile ngomqondo wokufaka i-suppository, i-sildenafil ingase ibe yindlela engcono kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Alprostadil (Urethral Route)

Ingabe i-Alprostadil (Urethral Route) iphephile Emadodeni Anesifo Senhliziyo?

Ama-suppository e-Alprostadil angaba yiphephile emadodeni anezimo zenhliziyo ezithile uma kuqhathaniswa nemithi yomlomo yokungasebenzi kahle kwe-erectile. Ngokungafani ne-sildenafil nemithi efanayo, i-alprostadil ayisebenzisani kakhulu nemithi yenhliziyo efana nama-nitrate. Noma kunjalo, kufanele uxoxe ngesimo sakho senhliziyo nodokotela wakho ngokucophelela ngaphambi kokuqala lo muthi.

Lo muthi ungabangela izinguquko zesikhashana ekucindezelweni kwegazi nesilinganiso senhliziyo, ngakho-ke udokotela wakho uzofuna ukukuqapha ngokucophelela uma unesifo senhliziyo. Amadoda anezimo zenhliziyo ezingazinzile, ukuhlaselwa yinhliziyo kwakamuva, noma ukuhluleka kwenhliziyo okukhulu kungase kudingeke ukuthi agweme zonke izindlela zokwelapha ukungasebenzi kahle kwe-erectile kuze kube yilapho isimo senhliziyo yabo silawulwa kangcono.

Ngingenzani Uma Ngingahlosi Ukusebenzisa I-Alprostadil Eningi Kakhulu?

Uma ngempela ufaka ama-suppository angaphezu kwelilodwa noma usebenzisa umthamo ophezulu kunalowo obekiwe, xhumana nodokotela wakho noma funa usizo lwezokwelapha ngokushesha. Ukusebenzisa i-alprostadil eningi kakhulu kungabangela ukuvuvukala isikhathi eside (priapism), ukwehla okukhulu ekucindezelweni kwegazi, noma ezinye izinkinga ezinzima.

Ungalindi ukubona ukuthi ngabe izimpawu ziyavela yini - kungcono ukuqapha futhi uthole iseluleko sezokwelapha ngokushesha. Uma uhlangabezana nokuqina okuhlala ngaphezu kwamahora angu-4, isiyezi esikhulu, ukuquleka, noma ubunzima bokuphefumula, iya egumbini eliphuthumayo ngokushesha. Lezi zimpawu zidinga ukwelashwa okuphuthumayo.

Kufanele Ngenzeni Uma Ngeqe Umthamo We-Alprostadil?

Njengoba ama-alprostadil suppositories esetshenziswa kuphela uma edingeka emsebenzini wezocansi, akukho okuthiwa "umthamo oqediwe" ngomqondo wendabuko. Lo muthi awuthathwa ngeshejuli ejwayelekile njengemithi yansuku zonke. Umane nje uwusebenzise uma uhlela ukuba nomsebenzi wezocansi.

Uma uhlose ukusebenzisa i-suppository kodwa wakhohlwa, usengayisebenzisa uma nje ungadluli imvamisa ephezulu enconyiwe. Khumbula ukuthi ungasebenzisi ama-suppositories angaphezu kwamabili esikhathini samahora angu-24 noma izikhathi ezingaphezu kweziyisikhombisa ngesonto.

Ngingayeka Nini Ukuthatha I-Alprostadil?

Ungayeka ukusebenzisa ama-alprostadil suppositories nganoma yisiphi isikhathi ngaphandle kokudinga ukunciphisa umthamo kancane kancane. Njengoba lo muthi usetshenziswa kuphela uma kudingeka, akukho ngozi yezimpawu zokuhoxisa noma imiphumela yokubuyela emuva uma uyeka ukuwusebenzisa.

Noma kunjalo, kungumqondo omuhle ukuxoxa nodokotela wakho uma uhlela ukuyeka ukusebenzisa umuthi unomphela. Bangase bafune ukuhlola ezinye izindlela zokwelapha noma baphenye ukuthi ngabe yiziphi izimo zempilo ezingaphansi ezishintshile. Amanye amadoda athola ukuthi ukwelapha izimo ezinjengesifo sikashukela noma umfutho wegazi ophezulu kuthuthukisa umsebenzi wawo wokwakha ngokwemvelo.

Ngingawasebenzisa Ama-Alprostadil Suppositories Ngekhondomu?

Yebo, ungasebenzisa amakhondomu ngama-alprostadil suppositories, futhi kuvame ukunconywa. Ukusebenzisa ikhondomu kungasiza ukuvikela umlingani wakho kunoma yimuphi umuthi osele futhi kunciphise ingozi yokudluliselwa kwezifo ezithathelwana ngocansi. I-suppository ngeke ithinte ukusebenza kwekhondomu.

Noma kunjalo, amanye amadoda aqaphela ukuthi imithi ingabangela ukuqaqamba okuncane noma ukuncipha komuzwa, okungase kuthinte ulwazi lwabalingani bobabili. Uma uhlangabezana nanoma yiziphi izimpawu ezingavamile noma uma umlingani wakho ezwa ukucasuka, xhumana nodokotela wakho mayelana nendlela engcono kakhulu yesimo sakho.