Yini i-Alvimopan: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Alvimopan iyimithi kadokotela esiza ukubuyisela ukusebenza kwamathumbu okuvamile ngemva kohlobo oluthile lokuhlinzwa. Yenzelwe ngqo ukulwa nokuqunjelwa kanye nokwehla kokugaya okungenzeka uma uhlinzwe okuhilela isisu sakho noma i-pelvis.

Cabanga ngayo njengomsizi oqondiwe osebenza ohlelweni lwakho lokugaya ukudla ukuze izinto ziqale ukuhamba futhi uma umzimba wakho udinga ukwesekwa okwengeziwe ngesikhathi sokululama. Udokotela wakho angase akunikeze lo muthi uma uhlinzwa amathumbu noma ezinye izinqubo ezingathinta isigqi esivamile somgudu wakho wokugaya ukudla.

Yini i-Alvimopan?

I-Alvimopan ingeyeqembu lemithi ebizwa ngokuthi ama-opioid antagonists. Isebenza ngokuvimba ama-receptors athile ohlelweni lwakho lokugaya ukudla anganciphisa ukuhamba kwamathumbu, ikakhulukazi ngemva kokuhlinzwa noma uma usebenzisa imithi yokwelapha ubuhlungu.

Lo muthi ukhethekile kakhulu futhi ngokuvamile usetshenziswa kuphela ezindaweni zasemtholampilo. Ngokungafani neminye imithi eminingi yokugaya ukudla ongase uyazi, i-alvimopan yenzelwe ukusetshenziswa kwesikhashana ngesikhathi sokululama esithile. Akuyona into ongayithatha ekhaya ngezinkinga zansuku zonke zokugaya ukudla.

Isetshenziselwani i-Alvimopan?

I-Alvimopan isetshenziswa ikakhulukazi ukusiza iziguli ukuthi zibuyisele ukusebenza kwamathumbu okuvamile ngemva kokuhlinzwa kwe-bowel resection. Lolu hlobo lokuhlinzwa luhlanganisa ukususa ingxenye yamathumbu akho amakhulu noma amancane, okungaphazamisa okwesikhashana isigqi esivamile sohlelo lwakho lokugaya ukudla.

Ngemva kwalolu hlobo lokuhlinzwa, abantu abaningi bahlangabezana nalokho odokotela abakubiza ngokuthi

Iqembu lakho lezempilo lingase futhi licabangele i-alvimopan uma uhlinzwa ezinye izindawo zesisu lapho kunengozi yokwehla kokugaya ukudla. Umgomo uwukusiza umzimba wakho ukuthi ubuyele emazingeni awo ajwayelekile okugaya ukudla ngokushesha, okungakusiza ukuthi uzizwe ungcono futhi mhlawumbe ubuye ekhaya ngokushesha.

Isebenza Kanjani I-Alvimopan?

I-Alvimopan ithathwa njengomuthi olungile oqine ngendlela eqondiswe kakhulu. Ivimba izamukeli ezithile ze-opioid emathunjini akho okugaya ukudla ngaphandle kokuthinta ukukhululeka kobuhlungu obungase ukuthola kweminye imithi.

Uma uhlinzwa, impendulo yomzimba wakho yokucindezeleka kanye nanoma imiphi imithi yokwelapha ubuhlungu oyitholayo kunganciphisa uhlelo lwakho lokugaya ukudla. I-Alvimopan isiza ukulwa nalokhu ngokuqeda lezi zimpawu zokuvimba ukuthi zingafinyeleli emathunjini akho. Lokhu kuvumela imisipha yakho yokugaya ukudla ukuthi iqale ukusebenza ngokujwayelekile futhi.

Umuthi usebenza endaweni yangakini ohlelweni lwakho lokugaya ukudla, okusho ukuthi ugxila emiphumeleni yawo lapho uyidinga kakhulu. Awungeni ngokuphawulekayo emsingeni wakho wegazi noma uthinte ezinye izindawo zomzimba wakho ngendlela eyenziwa yeminye imithi.

Kufanele Ngiyithathe Kanjani I-Alvimopan?

I-Alvimopan inikezwa njenge-capsule oyigwinyayo, ngokuvamile ngenkathi usasesibhedlela. Ithimba lakho lezempilo lizokunikeza umthamo wokuqala ngaphambi kokuhlinzwa kwakho, ngokuvamile kungakapheli amahora ambalwa ngemva kwenqubo.

Ungayithatha le mithi ngaphandle kokudla, futhi ayidingi noma yiziphi izinto ezikhethekile zokudla. Uma ukwazi ukuphuza amanzi, kulungile ukuthatha ne-capsule yakho. Ithimba lakho lezokwelapha lizosingatha isikhathi futhi liqinisekise ukuthi uthola imithamo yakho uma uyidinga.

Njengoba le mithi isetshenziswa esibhedlela, ngeke kudingeke ukhathazeke ngokukhumbula ukuyithatha wedwa. Abahlengikazi bakho bazokulethela ngesikhathi esifanele futhi bangaphendula noma yimiphi imibuzo onayo mayelana nokuyithatha.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Alvimopan?

I-Alvimopan yenzelwe ukusetshenziswa kwesikhashana, ngokuvamile akudluli izinsuku eziyi-7. Iziguli eziningi ziyithatha izinsuku eziyi-3 kuya kweziyi-5, kuye ngokuthi ngokushesha kangakanani uhlelo lwazo lokugaya ukudla lubuyela kokujwayelekile ngemva kokuhlinzwa.

Ithimba lakho lezempilo lizobheka intuthuko yakho futhi linqume ukuthi liyeka nini umuthi ngokusekelwe ekutheni ululama kanjani. Izimpawu zokuthi usukulungele ukuyeka zingabandakanya ukuba nokunyakaza kwamathumbu kwakho kokuqala, ukuzwa ukuqunjelwa okuncane, noma ukwazi ukubekezelela ukudla okuvamile futhi.

Umuthi uhloselwe ngqo ukuxhumanisa igebe phakathi kokuhlinzwa nokululama kwakho okuvamile. Uma uhlelo lwakho lokugaya ukudla lusebenza kahle futhi, ngeke kudingeke ukuthi uqhubeke ukuwuthatha.

Yiziphi Izimo Ezingezinhle Zomuthi i-Alvimopan?

Abantu abaningi bayawubekezelela kahle i-alvimopan, kodwa njenganoma imuphi umuthi, ingabangela ezinye izimo ezingezinhle. Izindaba ezinhle ukuthi izimo ezingezinhle ezingathi sína azivamile, futhi ithimba lakho lezokwelapha lizokubheka eduze ngenkathi uwuthatha.

Nawa amanye amaphutha avamile ongase uwahlangabezane nawo, ukhumbula ukuthi amaningi ala angahle ahlobane nokuhlinzwa kwakho kwakamuva:

• Ukucanuzela kwenhliziyo noma ukungakhululeki kwesisu okuncane
• Ikhanda
• Isiyezi
• Ukukhathala noma ukukhathala
• Ubuhlungu emhlane
• Ukuqunjelwa okuncane (nakuba lokhu ngokuvamile yilokho esizama ukukwelapha)

Lezi zimpawu ngokuvamile zithambile futhi zesikhashana. Ithimba lakho lezempilo lingakusiza ukuthi ulawule noma yikuphi ukungakhululeki okuhlangenwe nakho.

Kunezinye izimo ezingavamile kodwa ezingathi sína ukuthi ithimba lakho lezokwelapha lizozibheka ngokucophelela:

• Ubuhlungu obukhulu besisu obuhlukile ebuhlungwini bakho bokuhlinzwa
• Izimpawu zezinkinga zenhliziyo (ubuhlungu besifuba, ukushaya kwenhliziyo okungajwayelekile)
• Ukuphefumula kanzima
• Ukuphendula okukhulu komzimba (ukuqubuka, ukuvuvukala, ukungakwazi ukugwinya)

Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezingathi sína, ithimba lakho lezempilo lizozixazulula ngokushesha. Khumbula, usendaweni eqashwe lapho usizo luhlala lutholakala khona.

Obani okungafanele bathathe i-Alvimopan?

I-Alvimopan ayilungile kuwo wonke umuntu, futhi ithimba lakho lokunakekelwa kwezempilo lizohlola ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Kunezimo eziningana lapho lo muthi kungenzeka ungabi yindlela engcono kakhulu kuwe.

Akufanele uthathe i-alvimopan uma unezifo ezithile zenhliziyo, ikakhulukazi uma uke wahlaselwa yinhliziyo muva nje. Umuthi ungase ukwazi ukuthinta ukushaya kwenhliziyo yakho, ngakho udokotela wakho uzocabangela impilo yakho yenhliziyo nemithambo yegazi ngokucophelela.

Nawa amanye amakhambi angase enze i-alvimopan ingakulungele:

• Ukuhlaselwa yinhliziyo kwamuva noma isifo senhliziyo esibi
• Isifo sezinso esibi
• Isifo sesibindi esibi
• Ukungezwani okwaziwayo ne-alvimopan noma imithi efanayo
• Ukukhulelwa noma ukuncelisa (idatha yokuphepha elinganiselwe iyatholakala)
• Ukuvinjelwa kwamathumbu okuphelele

Ithimba lakho lokuhlinzwa lizobuyekeza zonke lezi zinto ngaphambi kokunquma ukuthi i-alvimopan ilungele yini isimo sakho. Bazophinda bacabangele noma imiphi eminye imithi oyithathayo ukuze baqiniseke ukuthi ngeke kube khona ukuxhumana okuyinkinga.

Igama Lomkhiqizo we-Alvimopan

I-Alvimopan ithengiswa ngaphansi kwegama lomkhiqizo elithi Entereg e-United States. Le yindlela ejwayelekile ozoyibona ikhonjiswa ngayo ezindaweni zasemtholampilo nakumarekhodi akho ezokwelapha.

Noma ngabe ithimba lakho lokunakekelwa kwezempilo libhekisela kuyo njenge-alvimopan noma i-Entereg, bakhuluma ngomuthi ofanayo. Ezinye izazi zezokwelapha zisebenzisa igama elivamile (alvimopan) kanti ezinye zingase zisebenzise igama lomkhiqizo (Entereg).

Ezinye izindlela ze-Alvimopan

Kunezindlela eziningana ezingase zicatshangelwe yithimba lakho lokunakekelwa kwezempilo zokuphatha izinkinga zokugaya ukudla ngemva kokuhlinzwa, nakuba i-alvimopan yenzelwe ngqo le njongo. Ukukhetha kuncike esimweni sakho ngasinye nomlando wezokwelapha.

Ezinye izindlela udokotela wakho angase azicabangele zihlanganisa:

• I-Methylnaltrexone (Relistor) - omunye umelene ne-opioid osebenza ngendlela ehlukile
• I-Simethicone - isiza ngamagesi nokuqunjelwa
• I-Docusate - i-stool softener engasiza ngokuqunjelwa
• Ukunyakaza kwasekuqaleni kanye nezinguquko ekudleni
• Ukucindezelwa kwe-Nasogastric kwezinye izimo

Ngamunye walezi zindlela usebenza ngendlela ehlukile, futhi ithimba lakho labahlinzi lizokhetha inketho engcono kakhulu ngokusekelwe ohlotsheni lwakho oluthile lokuhlinzwa, impilo yakho yonke, nokuthi ululama kanjani. Ngezinye izikhathi inhlanganisela yezindlela isebenza kangcono.

Ingabe i-Alvimopan ingcono kune-Methylnaltrexone?

Kokubili i-alvimopan ne-methylnaltrexone bangabamelene ne-opioid, kodwa zenzelwe izimo ezihlukene. I-Alvimopan idalelwe ngokuqondile ukusetshenziswa kwesikhashana ngemva kokuhlinzwa kwamathumbu, kuyilapho i-methylnaltrexone ivame ukusetshenziselwa ukuqunjelwa okubangelwa yi-opioid yesikhathi eside.

I-Alvimopan ivame ukuba eqondiswe kakhulu ekululameni ngemva kokuhlinzwa ngoba inikezwa ngaphambi nangemva kokuhlinzwa ngokushesha. Yenzelwe ukuvimbela ukwehla kokugaya okwenzeka njalo ngemva kwezinqubo zesisu. I-Methylnaltrexone ivame ukusetshenziswa lapho umuntu esebenzisa imithi yokwelapha ubuhlungu ye-opioid isikhashana futhi enokuqunjelwa okuqhubekayo.

Ithimba lakho lokunakekelwa kwezempilo lizokhetha umuthi ofaneleka kakhulu esimweni sakho esithile. Bazocabangela izinto ezinjengohlobo lokuhlinzwa okwenzayo, uhlelo lwakho lokuphatha ubuhlungu, nesimo sakho sempilo esiphelele.

Imibuzo Evame Ukubuzwa Mayelana ne-Alvimopan

Ingabe i-Alvimopan iphephile ezigulini zenhliziyo?

I-Alvimopan idinga ukuqapha okukhethekile kubantu abanezimo zenhliziyo. Uma unomlando wezinkinga zenhliziyo, ithimba lakho lokunakekelwa kwezempilo lizohlola ngokucophelela izinzuzo nezingozi ngaphambi kokunquma lo muthi.

Umuthi uhlotshaniswe nemiphumela ethile yenhliziyo nemithambo yegazi ocwaningweni lwezempilo, ikakhulukazi kubantu abaye baba nezifo zenhliziyo zakamuva noma isifo senhliziyo esibi. Ithimba lakho lezokwelapha lizobheka ukusebenza kwenhliziyo yakho ngokucophelela uma uthatha i-alvimopan futhi unokukhathazeka okuhlobene nenhliziyo.

Uma unezimo zenhliziyo ezithambile ezilawulwa kahle, i-alvimopan ingase ibe yindlela yokwelapha kuwe. Udokotela wakho wenhliziyo kanye nethimba lokuhlinzwa bazosebenzisana ukwenza isinqumo esiphephe kakhulu esimweni sakho esithile.

Kufanele Ngenzeni Uma Ngithatha I-Alvimopan Engakanani Ngengozi?

Njengoba i-alvimopan inikezwa endaweni yasesibhedlela, ukweqisa ngengozi akunakwenzeka. Ithimba lakho lezempilo lilawula ukulinganisa nesikhathi, ngakho akudingeki ukhathazeke ngokuthatha okuningi wedwa.

Uma unokukhathazeka ngomthamo wakho noma uhlangabezana nanoma yiziphi izimpawu ezingavamile, yazisa umhlengikazi wakho noma udokotela ngokushesha. Bangahlola ukuthi izimpawu zakho zihlobene yini nomuthi noma ezinye izici zokululama kwakho.

Indawo yesibhedlela inikeza isendlalelo esengeziwe sokuphepha ngoba ithimba lakho lezokwelapha likubheka ngokuqhubekayo futhi lingasabela ngokushesha kunoma yikuphi ukukhathazeka.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Alvimopan?

Endaweni yesibhedlela, ithimba lakho lezempilo liphatha isimiso sakho semithi, ngakho ukuphuthelwa umthamo akuvamile. Uma ngasizathu simbe umthamo uhlehliswa, umhlengikazi wakho noma udokotela uzonquma inkambo engcono kakhulu.

Ungakhathazeki ngokuzama ukuthi "ubambe" imithamo ephuthelwe. Ithimba lakho lezokwelapha lizolungisa isimiso sakho semithi njengoba kudingeka ngokusekelwe ekuqhubekeleni phambili kokululama kwakho kanye nesimo samanje.

Into ebaluleke kakhulu ukuxhumana nethimba lakho lezempilo mayelana nanoma yikuphi ukukhathazeka onakho ngesimiso sakho semithi.

Ngingayeka Nini Ukuthatha I-Alvimopan?

Iqembu lakho lezempilo lizinqumela ukuthi lizoyeka nini ukusebenzisa i-alvimopan ngokusekelwe ekuqhubekeni kwakho kokululama. Ngokuvamile, lokhu kwenzeka lapho isimiso sakho sokugaya ukudla sisebenza ngendlela ejwayelekile futhi, okungase kuboniswe ngokuba nokunyakaza kwamathumbu, ukubekezelela ukudla kahle, nokuzizwa ungagcwali kakhulu.

Abantu abaningi bathatha i-alvimopan izinsuku eziyi-3 kuya kweziyi-7 ngemva kokuhlinzwa. Isikhathi esiqondile sincike ekutheni umzimba wakho ululama ngokushesha kangakanani nokuthi usabela kahle kangakanani emuthini.

Ngeke kudingeke ukuthi uyeke lo muthi kancane kancane. Uma iqembu lakho lezokwelapha linquma ukuthi sekuyisikhathi sokuyeka, lizomane limyeke. Isimiso sakho sokugaya ukudla kufanele siqhubeke sisebenza ngendlela ejwayelekile ngaphandle kokusekelwa komuthi.

Ngingayithatha ekhaya i-Alvimopan?

I-Alvimopan njengamanje ivunyelwe kuphela ukusetshenziswa ezindaweni zasemtholampilo lapho iziguli zingaqashwa khona ngokusondela. Ayitholakali ukusetshenziswa ekhaya, okuyisici sokuphepha esinikezwe imiphumela engaba khona yomuthi nesidingo sokuqashwa kwezokwelapha.

Lo mkhawulo wasemtholampilo kuphela uqinisekisa ukuthi uthola umuthi ngaphansi kwezimo eziphephile kakhulu. Ithimba lakho lezokwelapha lingaqapha ukusabela kwakho futhi libhekane nanoma yiziphi izinkathazo ngokushesha.

Uma ukhishwe esibhedlela, isimiso sakho sokugaya ukudla kufanele sisebenze kahle ngokwanele ukuthi ngeke kudingeke uqhubeke nalo muthi ekhaya.