Yini i-Asenapine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Asenapine iyimithi elwa nokucindezeleka engasiza ukulinganisa amakhemikhali athile ebuchosheni bakho. Yenzelwe ngqo ukuthi incibilike ngaphansi kolimi lwakho, okuyenza isebenze ngempumelelo kunamaphilisi owagwinyayo. Le mithi ivame ukunqunywa ngezimo ezingokwengqondo ezingathi sína njenge-bipolar disorder kanye ne-schizophrenia.

Yini i-Asenapine?

I-Asenapine iyimithi kadokotela okuyimithi eqenjini elibizwa ngokuthi ama-antipsychotics angajwayelekile. Isebenza ngokusiza ukubuyisela ibhalansi yezinto zemvelo ebuchosheni bakho, ikakhulukazi i-dopamine ne-serotonin. Lawa makhemikhali obuchopho adlala indima ebalulekile emizweni, ekucabangeni, nasekuziphatheni.

Okuhlukanisa i-asenapine ukuthi iza njenge-sublingual tablet, okusho ukuthi uyibeka ngaphansi kolimi lwakho lapho incibilika khona ngokuphelele. Le ndlela ekhethekile yokulethwa isiza umzimba wakho ukuba umunce imithi ngempumelelo kunezindlela zokwelapha zamaphilisi owagwinyayo.

Imithi iyatholakala ngamandla ahlukene futhi ivame ukunqunywa njengengxenye yohlelo olubanzi lokwelashwa olungase luhlanganise ukwelashwa kanye nezinguquko zokuphila.

Isetshenziselwani i-Asenapine?

I-Asenapine isetshenziselwa ikakhulukazi ukwelapha izimo ezimbili eziyinhloko zempilo yengqondo: i-bipolar disorder kanye ne-schizophrenia. Nge-bipolar disorder, isiza ukuphatha kokubili iziqephu ze-manic kanye neziqephu ezixubile, okuyizikhathi lapho ungase uhlangabezane nezimpawu zombili i-mania nokucindezeleka ngesikhathi esifanayo.

Ekwelashweni kwe-schizophrenia, i-asenapine isiza ukunciphisa izimpawu ezinjengokucabanga, ukukhohlisa, nokucabanga okungahlelekile. Kungasiza futhi ngezimpawu ezingezinhle njengokuncipha kwesikhuthazo noma ubunzima bokuzwakalisa imizwa.

Ngezinye izikhathi odokotela banquma i-asenapine ezinye izimo uma bekholelwa ukuthi ingasiza, nakuba lokhu kungavamile. Udokotela wakho uzohlola ngokucophelela isimo sakho esithile ukuze anqume ukuthi i-asenapine ikufanele yini.

Isebenza Kanjani i-Asenapine?

I-Asenapine isebenza ngokuvimba izamukeli ezithile ebuchosheni bakho ezisabela ku-dopamine kanye ne-serotonin. Cabanga ngalezi zamukeli njengama-lock, namakhemikhali obuchopho njengamakhi. Uma kunomsebenzi omningi kakhulu kula ma-lock, kungabangela izimpawu zokugula ngengqondo.

Ngokuvimba ezinye zalezi zamukeli, i-asenapine isiza ukunciphisa ukusebenza ngokweqile ezindleleni ezithile zobuchopho ngenkathi ivumela ukusebenza okujwayelekile kobuchopho ukuthi kuqhubeke. Lesi senzo sokulinganisela sisiza ukuthuthukisa izimpawu ngaphandle kokuvala ngokuphelele lezi zinhlelo ezibalulekile zobuchopho.

I-Asenapine ithathwa njengomuthi oqinile olinganiselwe we-antipsychotic. Isebenza ngempumelelo ekuphatheni izimpawu kodwa ivame ukuba nemiphumela emibi embalwa uma iqhathaniswa nemithi emidala ye-antipsychotic.

Kufanele Ngiyithathe Kanjani I-Asenapine?

Ukuthatha i-asenapine ngendlela efanele kubalulekile ukuze isebenze kahle. Udinga ukubeka ithebhulethi ngaphansi kolimi lwakho bese uyivumela ukuthi incibilike ngokuphelele, okuthatha imizuzwana engaba ngu-30 kuya emizuzwini embalwa. Ungahlafuni, uchoboze, noma ugwinye ithebhulethi yonke.

Nakhu okudingeka ukwazi mayelana nesikhathi nokudla. Kufanele ugweme ukudla noma ukuphuza noma yini imizuzu eyi-10 ngemuva kokuthatha i-asenapine. Lesi sikhathi sokulinda siqinisekisa ukuthi umzimba wakho ungamunca umuthi ngendlela efanele ngezicubu ezingaphansi kolimi lwakho.

Abantu abaningi bathatha i-asenapine kabili ngosuku, ngokuvamile ekuseni nakusihlwa. Udokotela wakho uzoqala ngomthamo ophansi futhi angawukhulisa kancane kancane ngokuya ngendlela osabela ngayo emuthini kanye nanoma yimiphumela emibi oyitholayo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Asenapine?

Ubude bokwelashwa nge-asenapine buhluka kakhulu kumuntu nomuntu. Abanye abantu bangase badinge ukuyithatha izinyanga eziningana, kanti abanye bangase badinge ukwelashwa kwesikhathi eside okuthatha iminyaka. Udokotela wakho uzosebenza nawe ukunquma ubude obufanele ngokuya ngesimo sakho nokusabela ekwelashweni.

Ngesifo se-bipolar, ungase uthathe i-asenapine ngesikhathi sokuhlaselwa okukhulu bese uyiqhubeka njengokwelashwa kokugcina ukuvimbela ukuhlaselwa okuzayo. Ngesifo sengqondo, ukwelashwa kuvame ukuba isikhathi eside ukusiza ukugcina ukuzinza nokuvimbela ukuphindeka kwezimpawu.

Kubalulekile ukuthi ungalokothi uyeke ukuthatha i-asenapine ngokuzumayo, ngisho noma uzizwa ungcono. Udokotela wakho uzokusiza ukuthi unciphise kancane kancane umthamo uma sekuyisikhathi sokuyeka umuthi, okusiza ukuvimbela izimpawu zokuhoxisa noma ukubuyela kwezimpawu.

Yiziphi Izinkinga Zaseceleni Ze-Asenapine?

Njengayo yonke imithi, i-asenapine ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi okulindelekile kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa ukozela, isiyezi, kanye nezinguquko ekunambithekeni noma ukuba ndikindiki emlonyeni wakho. Le miphumela ehlobene nomlomo yenzeka ngoba umuthi uyancibilika ngaphansi kolimi lwakho futhi ngokuvamile imnene futhi yesikhashana.

Nawa amanye imiphumela emibi ebikwa kaningi evame ukulawuleka:

• Ukozela noma ukuzizwa ulele emini
• Isiyezi, ikakhulukazi uma usukuma ngokushesha
• Umlomo owomile noma izinguquko ekunambithekeni
• Ukukhuluphala, okungase kube kancane kancane
• Ukungazinzi noma ukuzizwa ungenakuhlala
• Isicanucanu noma ukungakhululeki kwesisu

Le miphumela emibi evamile ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala okwelashwa.

Abanye abantu bangase babe nemiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha. Nakuba lokhu kungavamile, kubalulekile ukukwazi ukuze ukwazi ukufuna usizo uma kudingeka.

Imiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha ihlanganisa:

• Ukuqina kwemisipha okukhulu noma ama-spasms
• Umkhuhlane omkhulu nokudideka noma ukujuluka
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Isiyezi esikhulu noma ukuquleka
• Ubunzima bokugwinya noma ukuphefumula
• Ukunyakaza okungalawuleki kobuso, ulimi, noma izitho

Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezinzima, xhumana nodokotela wakho ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo.

Kukhona nemiphumela embalwa engavamile kodwa engaba yingozi yesikhathi eside okufanele uyiqaphele. Lokhu kufaka phakathi isimo esibizwa ngokuthi i-tardive dyskinesia, esihilela ukunyakaza okungazithandeli okungase kube unomphela. Udokotela wakho uzokuhlola njalo ukuze abambe noma yiziphi izimpawu zakuqala zalesi simo.

Enye into engavamile kodwa ekhathazayo yi-neuroleptic malignant syndrome, okuyindlela engase ibe yingozi ebangela umkhuhlane omkhulu, ukuqina kwemisipha, kanye nezinguquko esimweni sengqondo. Nakuba lokhu kungavamile kakhulu, kubalulekile ukwazi izimpawu zokuxwayisa.

Ubani Ongafanele Athatha I-Asenapine?

I-Asenapine ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile zezokwelapha noma izimo zenza i-asenapine ingaphephile noma ingasebenzi kahle.

Akufanele uthathe i-asenapine uma uyiguliswa yiyo noma uke waba nokusabela okukhulu emithini efanayo esikhathini esidlule. Abantu abanezimo ezithile zenhliziyo, ikakhulukazi labo abanokushaya kwenhliziyo okungajwayelekile noma umlando wokuhlaselwa yinhliziyo, bangase badinge ukuqapha okukhethekile noma ezinye izindlela zokwelapha.

Nazi izimo lapho i-asenapine idinga ukuqapha okwengeziwe noma ingase inganconywa khona:

• I-Psychosis ehlobene ne-dementia ezigulini ezindala
• Isifo sesibindi esibi kakhulu
• Umlando wokuhlaselwa noma isithuthwane
• Isifo sikashukela noma ushukela ophezulu wegazi
• Ukwehla kwesibalo samaseli amhlophe egazi
• Ubunzima bokugwinya
• Ukukhulelwa noma ukuncelisa ibele

Udktela wakho uzolinganisela izinzuzo ezingaba khona nezingozi kulezi zimo futhi angase ancome ezinye izindlela zokwelapha noma adinge ukuqapha eduze uma i-asenapine iseyona inketho engcono kakhulu kuwe.

Amagama Omkhiqizo we-Asenapine

I-Asenapine itholakala ngaphansi kwegama lomkhiqizo elithi Saphris e-United States. Lolu uhlobo oluvame kakhulu ukunconywa lomuthi futhi yilolu oluvame ukutholakala ekhemisi lakho.

Kwamanye amazwe, i-asenapine ingase itholakale ngaphansi kwamanye amagama omkhiqizo, kodwa umuthi ngokwawo uhlala unjalo. Njalo qiniseka ukuthi uthola umuthi ofanele ngokuxhumana nomkhemisi wakho uma unemibuzo.

Izinhlobo ezijwayelekile ze-asenapine nazo ziyatholakala, ezinomuthi ofanayo osebenzayo kodwa zingase zibize kancane kunezinhlobo ezinamagama omkhiqizo.

Ezinye Izindlela Zokwelapha nge-Asenapine

Uma i-asenapine ingakulungele, kunezinye izindlela zokwelapha udokotela wakho angazicabangela. Ezinye izidakamizwa ezingajwayelekile ze-antipsychotics njenge-olanzapine, quetiapine, noma i-aripiprazole zisebenza ngendlela efanayo kodwa zinezinhlobo ezahlukene zemiphumela emibi.

Ngokuqondile ngesifo se-bipolar, izithuthukisi zemizwa ezinjenge-lithium noma ama-anticonvulsants afana ne-valproic acid kungaba ezinye izindlela. Udokotela wakho angase futhi acabangele ukwelashwa okuhlanganisiwe okusebenzisa imithamo ephansi yemithi eminingi.

Ukukhetha ezinye izindlela kuncike ezimpawini zakho ezithile, umlando wezokwelapha, nokuthi usabele kanjani kwezinye izindlela zokwelapha esikhathini esidlule. Okusebenza kahle kakhulu kuyahlukahluka kakhulu kumuntu nomuntu.

Ingabe i-Asenapine Ingcono Kune-Olanzapine?

Kokubili i-asenapine ne-olanzapine ziyizidakamizwa eziphumelelayo ze-antipsychotic, kodwa zinamandla nobuthakathaka obuhlukene. Ukukhetha okuthi "kungcono" kuncike ngokuphelele esimweni sakho nezidingo zakho.

I-Asenapine ingase ibangele ukuzuza isisindo esincane nezinkinga ezimbalwa ze-metabolic uma iqhathaniswa ne-olanzapine, okungaba kubalulekile uma ukhathazekile ngesifo sikashukela noma isifo senhliziyo. Kodwa-ke, i-olanzapine ifundwe isikhathi eside futhi ingase isebenze kangcono ngezimpawu ezithile.

Indlela yokulethwa ye-sublingual ye-asenapine ingaba yinzuzo kwabanye abantu, njengoba ingase isebenze ngokushesha futhi ibangele imiphumela emibi embalwa ehlobene nesisu. Udokotela wakho uzokusiza ukuthi ulinganise lezi zinto ngokusekelwe kuphrofayili yakho yezempilo ethile kanye nemigomo yokwelashwa.

Imibuzo Evame Ukubuzwa Mayelana ne-Asenapine

Umbuzo 1. Ingabe i-Asenapine iphephile ku-Diabetes?

I-Asenapine ingathinta amazinga kashukela egazini, ngakho-ke abantu abanesifo sikashukela badinga ukuqapha ngokucophelela ngenkathi bethatha lo muthi. Kungase kubangele ukuthi ushukela wakho wegazi unyuke, okungenza isifo sikashukela sibe nzima ukusilawula.

Uma unesifo sikashukela, udokotela wakho cishe uzohlola ushukela wakho wegazi kaningi lapho uqala i-asenapine futhi kungase kudingeke ukuthi alungise imithi yakho yesifo sikashukela. Lokhu akusho ukuthi awukwazi ukuthatha i-asenapine, kodwa kudinga ukuqashwa kwezokwelapha okuseduze.

Umbuzo 2. Kufanele ngenzeni uma ngiphuzile i-Asenapine eningi ngengozi?

Uma ngengozi uthatha i-asenapine eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ungalindi ukubona ukuthi uzizwa ulungile yini, njengoba izimpawu zokweqisa zingase zingaveli ngokushesha.

Izimpawu zokweqisa ze-asenapine zingabandakanya ukozela okukhulu, ukudideka, ukushaya kwenhliziyo okusheshayo, noma ubunzima bokuphefumula. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, funa ukunakekelwa kwezempilo eziphuthumayo ngokushesha.

Umbuzo 3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Asenapine?

Uma uphuthelwa umthamo we-asenapine, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ubuyisele umthamo owuphuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha izikhumbuzi zocingo noma ukusebenzisa umhleli wamaphilisi.

Q4. Ngingayeka nini ukuthatha i-Asenapine?

Kufanele uyeke kuphela ukuthatha i-asenapine ngaphansi kokuqondisa kukadokotela wakho. Noma ngabe uzizwa ungcono kakhulu, ukuyeka kungazelelwe kungabangela izimpawu zokuhoxisa noma ukubuyela ezimpawini zakho zokuqala.

Udkt wakho ngokuvamile uzokwehlisa umthamo wakho kancane kancane phakathi namasonto amaningana noma izinyanga lapho sekuyisikhathi sokuyeka umuthi. Le nqubo yokunciphisa isiza umzimba wakho ukuthi ujwayele futhi inciphisa ingozi yezinkinga.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Asenapine?

Kungcono ukugwema utshwala ngenkathi uthatha i-asenapine, ngoba kungakhuphula ukozela nesiyezi. Utshwala bungaphazamisa nokusebenza komuthi futhi bungase lenze izimpawu zesimo sakho sempilo yengqondo zibe zimbi.

Uma ukhetha ukuphuza ngezikhathi ezithile, khuluma nodokotela wakho ngemikhawulo ephephile futhi uqaphele kakhulu ngemisebenzi edinga ukuqapha, njengokushayela. Ngisho namanani amancane otshwala angaba nemiphumela eqinile uma ihlanganiswe ne-asenapine.