Atorvastatin (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Atorvaliq, Lipitor
Mayelana naleli khambi
I-Atorvastatin isetshenziswa kanye nokudla okufanele ukuze iphansise amazinga e-kolesterol ne-triglyceride (amafutha) egazini. Le mishini ingasiza ekunciphiseni izinkinga zezokwelapha (isib. ubuhlungu obusengifubeni, ukuhlaselwa yinhliziyo, noma isifo sobuchopho) ezihambisana namafutha ahlanganisa imithambo yegazi. Ingasetshenziswa futhi ukuvimbela izinhlobo ezithile zezinkinga zenhliziyo nezimithambo zegazi kubantu abanezingozi zezinkinga zenhliziyo. I-Atorvastatin iyingxenye yeqembu lemithi ebizwa ngokuthi yi-HMG-CoA reductase inhibitors, noma i-statins. Isebenza ngokuvimba i-enzyme edingekayo emzimbeni ukuze enze i-kolesterol, futhi lokhu kunciphisa inani le-kolesterol egazini. Lona umuthi utholakala kuphela ngomyalelo wochwepheshe wezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekwahluleni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqululo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqakathekile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokwaleka, njengokudla, izibenge, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zezingane ezizobeka umkhawulo ekusebenziseni i-atorvastatin ezinganeni ezineminyaka eyi-10 kuya kweyi-17. Noma kunjalo, ukuphepha nokuphumelela akukaqiniswa ezinganeni ezineminyaka engaphansi kwengu-10 ukuze kuphathwe i-homozygous familial hypercholesterolemia (HoFH) ne-heterozygous familial hypercholesterolemia (HeFH) nasezinganeni ukuze kuphathwe ezinye izinhlobo zekholestrol eliphezulu. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezizobeka umkhawulo ekusebenziseni i-atorvastatin kubantu abadala. Noma kunjalo, iziguli ezikhulile zinezinkinga ezihlobene nobudala zezinkalankala, isibindi, inhliziyo, noma ingozi eyenyuke yemiphumela yemisipha, okungase kudinge ukunakekelwa kubantu abamukela i-atorvastatin. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kungenzeki ukuthi zisetshenziswe ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlaliswe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ayinconywa. Udokotela wakho angase anqume ukungakwelaphi ngale mithi noma ashintshe ezinye izimithi ozithathayo. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungase kudingeke kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo kungabangela ukwanda kengozi yezinye izingozi ezihambisana nemiphumela emibi, kodwa ukusebenzisa kokubili imithi kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nezinye izimithi kungase futhi kubangele ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngesisekelo sokubaluleka kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile ayinconywa, kodwa kungase kungakhuphuki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza kuphela njengoba kunqunyiwe udokotela wakho. Ungalisebenzisi kakhulu, ungalisebenzisi kaningi, futhi ungalisebenzisi noma isikhathi eside kunalokho udokotela wakho akuqondile. Ngaphezu kwalokhu leyeza, udokotela wakho angashintsha ukudla kwakho kube lokho okunefutha eliphansi, ushukela, nekolesterol. Landela ngokucophelela imiyalo yodokotela wakho mayelana nanoma yiluphi ukudla okukhethekile. Ukusebenzisa ukuxuba: Ukusebenzisa ithebulethi: Ungaphuzi uwoyela omningi nge atorvastatin. Lokhu kungabangela imiphumela engathandeki e-liver. Tshela udokotela wakho uma uhlala uphuza ijusi le grapefruit. Ukuphuza uwoyela omningi we grapefruit (ngaphezulu kwe-1.2 amamitha ngosuku) ngenkathi uthatha leli leyeza kungandisa ingozi yokulimaza imisipha futhi kungabangela izinkinga zezinso. Inani laleli leyeza lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani ajwayelekile aleli leyeza. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondile ukwenza kanjalo. Inani leyeza olithathayo lixhomeke emandleni eleyeza. Futhi, inani lezinye ulizithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezinye, nobude besikhathi othatha khona leyeza kuya ngenkinga yezokwelapha oyisebenzisela khona leyeza. Uma uphuthelwa yisilinganiso saleli leyeza, silithathe ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sesilinganiso sakho esilandelayo, susa isilinganiso esiphuthelwe bese ubuyela esikhathini sakho sokuthola isilinganiso. Ungawandisi ama-doses. Uma uphuthelwa yisilinganiso futhi sekwedlule amahora angaphezu kwama-12 kusukela esilinganisweni sakho sokugcina, linda bese uthatha isilinganiso sakho esilandelayo ngesikhathi sakho esivamile. Ungathathi ama-doses amabili aleli leyeza ngesikhathi esifanayo. Gcina leyeza esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungaganduki. Gcina kungafinyeleleki izingane. Ungagcini leyeza eliphelile noma leyeza elingasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele ulahle kanjani noma yiliphi leyeza olungalisebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.