Yini i-Atorvastatin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Atorvastatin iyimithi kadokotela esiza ukwehlisa amazinga e-cholesterol egazini lakho. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-statins, asebenza ngokuvimba i-enzyme isibindi sakho esiyisebenzisela ukwenza i-cholesterol. Ungase uyazi kangcono ngegama layo lomkhiqizo, i-Lipitor, futhi ingenye yemithi evame ukunqunywa kakhulu yokuphatha i-cholesterol ephezulu nokunciphisa ingozi yesifo senhliziyo.

Yini i-Atorvastatin?

I-Atorvastatin iyimithi ye-statin udokotela wakho ayinika ukusiza ukuphatha amazinga e-cholesterol. Kuyinhlanganisela yokwenziwa eqondise ngqo i-HMG-CoA reductase, i-enzyme isibindi sakho esidinga ukukhiqiza i-cholesterol. Cabanga ngayo njengokubeka ibhuleki elithambile enqubweni yomzimba wakho yokwenza i-cholesterol.

Le mithi iza njengepilisi yomlomo oyithatha ngomlomo, ngokuvamile kanye ngosuku. Itholakala ngamandla amaningana kusukela ku-10mg kuya ku-80mg, okuvumela udokotela wakho ukuthi athole umthamo ofanele wezidingo zakho ezithile. Imithi ifundwe kabanzi futhi isetshenziswe ngokuphepha yizigidi zabantu emhlabeni wonke selokhu yaqala ukugunyazwa.

Isetshenziselwani i-Atorvastatin?

I-Atorvastatin ikakhulukazi iphatha amazinga e-cholesterol aphezulu futhi isiza ekuvikeleni isifo senhliziyo nemithambo yegazi. Udokotela wakho ngokuvamile uzoyinquma uma izinguquko zokuphila njengokudla nokuzivivinya zingazange zehlise i-cholesterol yakho emazingeni anempilo. Isebenza ikakhulukazi ekwehliseni i-cholesterol ye-LDL, evame ukubizwa ngokuthi i-cholesterol "embi".

Ngaphandle kokuphathwa kwe-cholesterol, i-atorvastatin isebenza ngezinhloso eziningana ezibalulekile zempilo yenhliziyo yakho. Ingasiza ekuvikeleni ukuhlaselwa yinhliziyo nokushaywa unhlangothi kubantu abanesifo senhliziyo noma isifo sikashukela. Imithi futhi inciphisa ingozi yokudinga izinqubo ezinjenge-angioplasty noma ukuhlinzwa kwe-bypass.

Odokotela abathile banikeza i-atorvastatin kubantu abanezimo ezithile zofuzo ezibangela amazinga aphezulu kakhulu e-cholesterol. Iphinde isetshenziswe ngokuhlangana neminye imithi uma ukwelashwa okukodwa kunganele ukufinyelela emazingeni e-cholesterol afunekayo.

Isebenza Kanjani I-Atorvastatin?

I-Atorvastatin isebenza ngokuvimba i-HMG-CoA reductase, i-enzyme ebalulekile isibindi sakho esiyisebenzisela ukwenza i-cholesterol. Uma le enzyme ivinjelwe, isibindi sakho sikhiqiza i-cholesterol encane ngokwemvelo. Ngenxa yalokho, isibindi sakho sikhipha i-cholesterol eningi emithanjeni yakho yegazi ukuze sihlangabezane nezidingo zaso, okunciphisa inani elijikelezayo egazini lakho.

Lo muthi ubhekwa njenge-statin enamandla ngokulinganisela, enamandla kunezinye izinketho ezindala kodwa hhayi enamandla kunazo zonke ezitholakalayo. Ngokuvamile inciphisa i-LDL cholesterol ngama-30-50%, kuye ngomthamo owuthathayo. Imiphumela ivame ukubonakala phakathi kwamasonto angu-2-4 ngemuva kokuqala ukwelashwa.

I-Atorvastatin iphinda ibe nemiphumela emihle ngaphandle kokunciphisa i-cholesterol. Ingasiza ukuzinzisa ukwakheka kwe-plaque emithanjeni yakho futhi inciphise ukuvuvukala kuyo yonke imithambo yakho yenhliziyo. Lezi zinzuzo ezengeziwe zifaka isandla emiphumeleni yayo yokuvikela enhliziyweni yakho nemithanjeni yegazi.

Kufanele Ngiyithathe Kanjani I-Atorvastatin?

Thatha i-atorvastatin ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Ungayithatha ngokudla noma ngaphandle kokudla, njengoba ukudla kungawuthinti ngendlela ebalulekile umzimba wakho oyamukela ngayo umuthi. Abantu abaningi bakuthola kulula ukukhumbula uma beyithatha ngesikhathi esifanayo nsuku zonke, njengokudla kwakusihlwa noma ngaphambi kokulala.

Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele. Ungayichobozi, uyihlukanise, noma uyihlafune ithebhulethi, njengoba lokhu kungathinta indlela umuthi osebenza ngayo. Uma unenkinga yokugwinya amaphilisi, khuluma nodokotela wakho mayelana nezinketho ezingezinye noma amasu angasiza.

Kufanele uqaphele ukudla neziphuzo ezithile ngenkathi usebenzisa i-atorvastatin. Gwema ama-grapefruit nejusi lama-grapefruit, ngoba kungakhuphula inani lomuthi egazini lakho futhi kwandise ingozi yemiphumela emibi. Nciphisa ukusetshenziswa kotshwala, ngoba kokubili utshwala ne-atorvastatin kungathinta isibindi sakho.

Udkt wakho cishe uzoqala ngomthamo ophansi futhi angawulungisa ngokuya ngendlela ozabela ngayo kanye namazinga akho e-cholesterol. Ukuhlolwa kwegazi okuvamile kuzosiza ukuqapha inqubekela phambili yakho futhi kuqinisekise ukuthi umuthi usebenza ngempumelelo ngaphandle kokubangela izinkinga.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Atorvastatin?

Abantu abaningi badinga ukuthatha i-atorvastatin isikhathi eside, ngokuvamile iminyaka eminingi noma unomphela. I-cholesterol ephezulu ngokuvamile iyisimo esingapheli esidinga ukuphathwa okuqhubekayo kunokulungiswa kwesikhashana. Udkt wakho uzohlola njalo ukuthi usawudinga yini umuthi ngokuya ngamazinga akho e-cholesterol nempilo yakho yonke.

Ngokuvamile uzobona udkt wakho njalo emavikini ama-3-6 lapho uqala ukuthatha i-atorvastatin. Lokhu kuvakasha kuvumela udkt wakho ukuthi aqaphe ukuthi umuthi usebenza kahle kangakanani futhi ahlolisise noma yimiphi imiphumela emibi. Uma amazinga akho e-cholesterol esezinzile, ungase ube nokuhlolwa njalo, mhlawumbe njalo ezinyangeni eziyi-6-12.

Ungayeki ukuthatha i-atorvastatin ngokuzumayo ngaphandle kokukhuluma nodkt wakho kuqala. Uma uyeka ukuthatha ama-statins, amazinga akho e-cholesterol ngokuvamile abuyela emazingeni awo aphezulu angaphambilini kungakapheli amasonto ambalwa. Uma udinga ukuyeka umuthi nganoma yisiphi isizathu, udkt wakho angakusiza ukuthi wenze kanjalo ngokuphepha futhi axoxe ngezindlela zokwelapha ezingezinye.

Yini Imiphumela Emibi Ye-Atorvastatin?

Abantu abaningi bayayibekezelela i-atorvastatin kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela emibi engathí sina ayivamile, futhi abantu abaningi ababi nemiphumela emibi nhlobo.

Nawa amanye amaphutha avamile ongase uhlangabezane nawo, ukhumbula ukuthi lawa ngokuvamile athinta abantu abangaphansi koyedwa kwabayishumi:

• Ukuqaqamba kwemisipha noma ubuthakathaka, ikakhulukazi ezingalweni nasemilenzeni yakho
• Ikhanda elingase lizizwe lifana nekhanda elibangelwa ukungezwani
• Izinkinga zokugaya ukudla njengokucasuka, isifo sohudo, noma ukuqunjelwa
• Izimpawu zomkhuhlane ezivamile njengamakhala agobhozayo noma umphimbo obuhlungu
• Ubuhlungu bamalunga obungase buzizwe njengomdlavuza olula

Le miphumela emibi evamile ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi emasontweni ambalwa okuqala kokwelashwa.

Imiphumela emibi engavamile kodwa ekhathazayo idinga ukunakekelwa kwezokwelapha, nakuba yenzeka kubantu abangaphansi koyedwa kwabayi-100:

• Ubuhlungu obukhulu bemisipha noma ubuthakathaka obungathuthuki ngokuphumula
• Ukukhathala okungavamile noma ubuthakathaka obuphazamisa imisebenzi yansuku zonke
• Umchamo onombala omnyama noma ukuphuzi kwesikhumba namehlo
• Ukuqhubeka nokucasuka, ukuhlanza, noma ubuhlungu besisu
• Izinkinga zenkumbulo noma ukudideka

Uma uhlangabezana nanoma yiziphi zalezi zimpawu, xhumana nodokotela wakho ngokushesha ukuze uthole isiqondiso.

Imiphumela emibi engavamile kodwa ebucayi yenzeka kubantu abangaphansi koyedwa kwabayinkulungwane, kodwa idinga ukunakekelwa kwezokwelapha ngokushesha:

• I-Rhabdomyolysis - ukuhlukana okukhulu kwemisipha okungalimaza izinso
• Izinkinga zesibindi ezibangela ukukhathala okuqhubekayo, ukulahlekelwa isifiso sokudla, nobuhlungu besisu
• Ukungezwani komzimba okukhulu okunezinkinga zokuphefumula noma ukuvuvukala
• Isifo sikashukela esisha, ikakhulukazi kubantu abanezici eziyingozi

Ngenkathi le miphumela emibi ebucayi ikhathaza, khumbula ukuthi udokotela wakho unqume i-atorvastatin ngoba izinzuzo zempilo yakho yenhliziyo zidlula lezi zingozi kubantu abaningi.

Ubani Ongafanele Athathe I-Atorvastatin?

I-Atorvastatin ayiphephile kuwo wonke umuntu, futhi abantu abathile kufanele bagweme lo muthi ngokuphelele. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuwunquma ukuze aqinisekise ukuthi kufaneleka kuwe.

Akufanele uthathe i-atorvastatin uma unesifo sesibindi esisebenzayo noma ukukhuphuka okuqhubekayo okungachazeki ekuhlolweni komsebenzi wesibindi. Umuthi ungase uqhubeke nokwenza izinkinga zesibindi zibe zimbi, ngakho udokotela wakho udinga ukuqinisekisa ukuthi isibindi sakho sinempilo ngaphambi kokuqala ukwelashwa.

Ukukhulelwa nokuncelisa ibele kuyizinto ezingavumelekile ngokuphelele ze-atorvastatin. Umuthi ungase ulimaze ingane esakhula, ngakho-ke abesifazane abakhulelwe, abahlela ukukhulelwa, noma abancelisa ibele akufanele bawuthathe. Uma ukhulelwa ngenkathi uthatha i-atorvastatin, yeka umuthi ngokushesha futhi uthinte udokotela wakho.

Abantu abanezifo ezithile zemisipha noma umlando wezinkinga zemisipha ngeminye imithi ye-statin bangase badinge ukugwema i-atorvastatin. Udokotela wakho uzohlola ubungozi bakho ngokucophelela, ikakhulukazi uma uke waba nobuhlungu bemisipha noma ubuthakathaka ngemithi efanayo esikhathini esidlule.

Izimo ezithile zezokwelapha zidinga ukuqapha okwengeziwe, futhi udokotela wakho angase akhethe omunye umuthi noma akuqaphe eduze:

• Isifo sezinso, njengoba singathinta indlela umzimba wakho osebenza ngayo umuthi
• Izifo ze-thyroid, ezingakhuphula ingozi yezinkinga zemisipha
• Ukusetshenziswa kotshwala obuningi, okungakhuphula izingozi ezihlobene nesibindi
• Ukuphendula komzimba okwedlule emithini ye-statin

Udokotela wakho uzohlola lezi zici ngokumelene nezinzuzo zokunciphisa i-cholesterol ukuze enze isinqumo esingcono kakhulu sesimo sakho somuntu ngamunye.

Amagama Omkhiqizo we-Atorvastatin

I-Atorvastatin yaziwa kakhulu ngegama layo lomkhiqizo i-Lipitor, okuyiyona nguqulo yokuqala eyenziwe yi-Pfizer. I-Lipitor yaba ngomunye wemithi ethengiswa kakhulu emhlabeni futhi isaziwa kakhulu ngaleli gama, yize izinhlobo ezivamile sezitholakala manje.

I-atorvastatin ejwayelekile manje iyatholakala kubakhiqizi abaningi futhi ngokuvamile ibiza kakhulu kune-brand-name version. Lezi zinhlobo ezijwayelekile ziqukethe isithako esifanayo esisebenzayo futhi zisebenza ngempumelelo njenge-Lipitor. Ikhemisi lakho lingase libe nezinhlobo ezahlukene ezijwayelekile, kodwa zonke zilingana ngokusebenza nokuphepha.

Amanye amagama e-brand e-atorvastatin afaka i-Atorlip, i-Atorva, ne-Lipvas, nakuba lokhu kungavamile e-United States. Udokotela wakho noma usokhemisi angakusiza ukuthi uqonde ukuthi iyiphi inguqulo ye-atorvastatin oyithathayo nokuthi ukushintsha phakathi kwemikhiqizo kufanele yini kuwe.

Ezinye izindlela ze-Atorvastatin

Imithi eminingi ehlukile ingasiza ekuphatheni i-cholesterol ephezulu uma i-atorvastatin ingakulungele. Eminye imithi ye-statin isebenza ngendlela efanayo ne-atorvastatin kodwa ingase ibe namaphrofayili ahlukene emiphumeleni noma amashejuli okulinganisa angahambisana kangcono nezidingo zakho.

Ezinye izindlela ezivamile ze-statin zifaka i-simvastatin, evame ukuba mnene futhi ingase ibangele izinkinga ezimbalwa zemisipha. I-Rosuvastatin (Crestor) inamandla kune-atorvastatin futhi ingase ikhethwe uma udinga ukuncishiswa kwe-cholesterol okunamandla. I-Pravastatin ingenye inketho engase ithuthukiswe kangcono ngabantu abanezinkinga zemisipha ngamanye ama-statins.

Imithi ye-cholesterol engeyona i-statin inikeza izindlela ezahlukene zokuphatha amazinga e-cholesterol. Lokhu kufaka i-ezetimibe (Zetia), evimbela ukumuncwa kwe-cholesterol emathunjini akho, kanye nemithi emisha efana ne-PCSK9 inhibitors enikezwa ngemijovo. Ama-bile acid sequestrants nama-fibrates ayizinketho ezengeziwe zezimo ezithile.

Udokotela wakho uzocabangela amazinga akho e-cholesterol, ezinye izimo zezempilo, nokuthi usabele kanjani ekwelashweni kwangaphambilini lapho ekhetha enye indlela engcono kakhulu kuwe.

Ingabe i-Atorvastatin ingcono kune-Simvastatin?

I-Atorvastatin ne-simvastatin yomibili imithi ye-statin esebenzayo, kodwa inomehluko obalulekile ongase wenze enye ilungele wena kunenye. I-Atorvastatin ngokuvamile inamandla amaningi, okusho ukuthi inganciphisa amazinga e-cholesterol ngokuphawulekayo ngemithamo elinganayo.

I-Atorvastatin inempilo ende, okusho ukuthi ihlala esistemini yakho isikhathi eside futhi ingathathwa nganoma yisiphi isikhathi sosuku. I-Simvastatin, ngakolunye uhlangothi, isebenza kahle uma ithathwa kusihlwa ngoba umzimba wakho ukhiqiza i-cholesterol eningi ebusuku. Lokhu kulungiswa kwesikhathi kungenza i-atorvastatin ilungele abanye abantu.

Uma kuziwa emiphumeleni emibi, yomibili imithi inamaphrofayili afanayo, kodwa abanye abantu bayayibekezelela enye kangcono kunenye. I-Simvastatin ingase ihlotshaniswe nezinkinga zemisipha ezingaphezulu kancane ngemithamo ephezulu, kuyilapho i-atorvastatin ingase ibangele izinkinga ezingaphezulu zokugaya ukudla kwabanye abantu.

Ukukhetha phakathi kwale mithi kuvame ukuncika emigomweni yakho ye-cholesterol, eminye imithi oyithathayo, nokuthi usabela kanjani ekwelashweni. Udokotela wakho angasiza ekutholeni ukuthi iyiphi inketho efaneleka kakhulu esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Atorvastatin

Ingabe i-Atorvastatin iphephile kubantu abanesifo sikashukela?

Yebo, i-atorvastatin ngokuvamile iphephile futhi ivame ukunconywa kubantu abanesifo sikashukela. Abantu abanesifo sikashukela banengozi eyengeziwe yesifo senhliziyo, futhi i-atorvastatin ingasiza ekunciphiseni le ngozi ngokunciphisa amazinga e-cholesterol. Iziqondiso eziningi zokwelashwa kwesifo sikashukela zincoma ngokuqondile ukwelashwa nge-statin kubantu abadala abaningi abanesifo sikashukela.

Nokho, ama-statin okuhlanganisa i-atorvastatin angakhuphula kancane amazinga kashukela egazini kwabanye abantu. Lo mphumela ngokuvamile umodest futhi awunqobi izinzuzo zenhliziyo nemithambo yegazi kubantu abaningi abanesifo sikashukela. Udokotela wakho uzoqapha amazinga akho kashukela egazini njalo futhi angase alungise imithi yakho yesifo sikashukela uma kudingeka.

Ngingenzani uma ngithatha i-Atorvastatin eningi ngengozi?

Uma ngabe uthathe i-atorvastatin eningi kunaleyo oyinikiwe, ungesabi, kodwa xhumana nodokotela wakho noma usokhemisi ukuze uthole isiqondiso. Ukuthatha umthamo owengeziwe ngezikhathi ezithile akunakwenzeka ukuthi kubangele ingozi enkulu, kodwa kubalulekile ukuthola iseluleko esivela ochwepheshe mayelana nokuthi yini okufanele uyenze ngokulandelayo.

Ungazami ukuthi "ulungise" umthamo owengeziwe ngokuqaqa umthamo wakho olandelayo ohleliwe. Kunalokho, buyela esimisweni sakho esijwayelekile sokuthatha imithi njengoba kuyalelwe ngumhlinzeki wakho wezempilo. Uma ngabe uthathe okuningi kakhulu kunomthamo wakho onikiwe noma uhlangabezana nezimpawu ezinjengobuhlungu obukhulu bemisipha, isicanucanu, noma ubuthakathaka, funa ukunakekelwa kwezempilo ngokushesha.

Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Atorvastatin?

Uma uphuthelwa umthamo we-atorvastatin, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kulokho, weqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe.

Ukuphuthelwa umthamo ngezikhathi ezithile ngeke kubangele izinkinga ngokushesha, kodwa zama ukuthatha imithi yakho ngokuqhubekayo ukuze uthole imiphumela engcono kakhulu. Uma uvame ukukhohlwa imithamo, cabangela ukusetha isikhumbuzi sansuku zonke ocingweni lwakho noma usebenzise umhleli wamaphilisi ukukusiza ukuthi uhlale emgqeni.

Ngingayeka Nini Ukuthatha I-Atorvastatin?

Kufanele uyeke kuphela ukuthatha i-atorvastatin ngaphansi kwesiqondiso sikadokotela wakho. I-cholesterol ephezulu ngokuvamile yisimo sempilo yempilo yonke esidinga ukuphathwa okuqhubekayo, ngakho-ke abantu abaningi badinga ukuqhubeka nokuthatha imithi yabo ye-statin isikhathi eside ukuze bagcine izinzuzo.

Udokotela wakho angase acabange ukuyeka i-atorvastatin uma uhlangabezana nemiphumela emibi engathuthukiswa, uma imigomo yakho ye-cholesterol ishintsha kakhulu, noma uma ezinye izimo zezempilo zenza ukusetshenziswa okuqhubekayo kungafaneleki. Bangase futhi bahlole kabusha isidingo sakho somuthi uma wenza izinguquko ezinkulu zokuphila eziqhubukayo ezithuthukisa kakhulu amazinga akho e-cholesterol.

Ngingakwazi Yini Ukuphuza Utshwala Ngenkathi Ngithatha I-Atorvastatin?

Ungakwazi ukuphuza utshwala ngokulinganisela ngenkathi usebenzisa i-atorvastatin, kodwa kubalulekile ukuqapha. Kokubili utshwala ne-atorvastatin kucutshungulwa yisibindi sakho, ngakho ukuphuza kakhulu kungakhuphula ingozi yezinkinga zesibindi. Odokotela abaningi batusa ukukhawulela utshwala kungadluli isiphuzo esisodwa ngosuku kwabesifazane neziphuzo ezimbili ngosuku kwabesilisa.

Uma unomlando wezinkinga zesibindi noma udokotela wakho eqapha ukusebenza kwesibindi sakho ngokucophelela, bangase batusa ukugwema utshwala ngokuphelele. Njalo xoxa ngokwethembeka ngokusebenzisa kwakho utshwala nodokotela wakho ukuze bakwazi ukukunikeza isiqondiso esiqondene nawe esisekelwe esimweni sakho sempilo.