Yini i-Baclofen (Indlela ye-Intrathecal): Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Baclofen elethwa ngendlela ye-intrathecal iyindlela yokwelapha ekhethekile lapho lo muthi okhulula imisipha ulethwa ngqo emanzini azungeze umgogodla wakho. Le ndlela eqondiswe ngqo isiza ekuphatheni ukuqina kwemisipha okukhulu lapho imithi edliwayo ingazange inikeze ukukhululeka okwanele.

Uma ubhekene nokuqina kwemisipha okukhulu noma ama-spasms aphazamisa impilo yansuku zonke, udokotela wakho kungenzeka ukuthi ukukhulumele ngale ndlela yokwelapha. Kuyindlela yokwelapha ebandakanya okuningi kunokuthatha amaphilisi, kodwa inganikeza ukukhululeka okukhulu ezimweni ezifanele.

Yini i-Baclofen (Indlela ye-Intrathecal)?

I-Baclofen ye-Intrathecal ingumuthi ofanayo okhulula imisipha ongase uwazi ngesimo samaphilisi, kodwa olethwa ngohlelo lwepompo olufakelwe ngokuhlinzwa. Le pompo ihlala ngaphansi kwesikhumba sakho, ngokuvamile esiswini sakho, futhi ithumela umuthi ngqo emanzini omgogodla wakho ngeshubhu elincane.

Le ndlela idlula ngqo uhlelo lwakho lokugaya ukudla, okwenza imithamo emincane kakhulu ifinyelele endaweni eqondile lapho kulawulwa khona imisipha. Cabanga ngayo njengokuletha umuthi ngqo emthonjeni kunokuthi uqale uhambe emzimbeni wakho wonke.

Uhlelo lwepompo lungaba ngosayizi we-hockey puck futhi ludinga ukugcwaliswa ngomuthi njalo ezinyangeni ezimbalwa ngendlela elula yehhovisi. Udokotela wakho uhlela ipompo ukuthi linikeze imithamo eqondile usuku lonke ngokusekelwe ezidingweni zakho ezithile.

Isetshenziselwani i-Baclofen (Indlela ye-Intrathecal)?

Le ndlela yokwelapha ngokuyinhloko isiza abantu abanokuqina kwemisipha okukhulu okungazange kuphendule kahle emithini edliwayo. Ukuqina kwemisipha kusho ukuthi imisipha yakho ihlala iqine, iqine, noma izinciphisa ngokuzenzakalela, okwenza ukunyakaza kube nzima noma kubuhlungu.

Izimo ezivame kakhulu ezizuzayo ku-baclofen ye-intrathecal zihlanganisa i-multiple sclerosis, ukulimala komgogodla, i-cerebral palsy, nokulimala kobuchopho okuthile. Lezi zimo zingabangela imisipha ukuthi iqine kangangokuthi iphazamise ukuhamba, ukuhlala, ukulala, noma ukuzinakekela.

Abanye abantu futhi bathola lokhu kwelashwa ngenxa yezinhlungu ezinzima zemisipha, i-dystonia (ukuqina kwemisipha okungahleliwe), noma izimo zobuhlungu ezingapheli lapho ukungezwani kwemisipha kudlala indima enkulu. Udokotela wakho uzohlola ngokucophelela ukuthi ungumuntu ofanelekayo yini ngokuqala ngenqubo yokuhlola.

Isebenza Kanjani i-Baclofen (Intrathecal Route)?

I-Baclofen isebenza ngokuvimba izimpawu zemizwa ethile emgogodleni wakho ezitshela imisipha ukuthi iqine noma ihlale iqine. Uma ilethwa nge-intrathecally, isebenza ngokuqondile kulezi zindlela zemizwa ezingeni lomgogodla lapho ukulawulwa kwemisipha kuqala khona.

Lokhu kuyenza ibe yindlela yokwelapha eqinile futhi eqondiwe uma iqhathaniswa namaphilisi e-baclofen omlomo. Ngenkathi imithi yomlomo kufanele idlule emithanjeni yakho yegazi futhi ithinte umzimba wakho wonke, indlela ye-intrathecal iletha imithi ngqo lapho idingeka kakhulu.

Umuthi usiza ukubuyisela ibhalansi engcono phakathi kwezimpawu zemizwa ezenza imisipha iqine naleyo ebasiza ukuthi baphumule. Lokhu kunganciphisa kakhulu ukuqina kwemisipha, ukuqina, nobuhlungu ngenkathi kuthuthukisa ikhono lakho lokuhamba nokusebenza.

Kufanele Ngiyithathe Kanjani i-Baclofen (Intrathecal Route)?

Awuyithathi ngempela le mithi ngendlela yendabuko ngoba ilethwa ngokuzenzakalelayo ngepompo yakho efakwe. Kodwa-ke, uzodinga ukulandela isimiso sikadokotela wakho sokugcwalisa nokulungisa ipompo.

Ngaphambi kokuthola ipompo elihlala njalo, uzodlula esikhathini sokuhlola lapho i-baclofen ifakwa ngqo emanzini akho omgogodla ngomgodi we-lumbar. Lolu vivinyo lusiza ukunquma ukuthi imithi izokusebenzela yini nokuthi yisiphi isilinganiso ongase usidinge.

Uma iphampu yakho isifakelwe, uzoba nama-aphoyintimenti avamile njalo ezinyangeni eziyi-1-3 ukuze ugcwalise umthombo womuthi. Udokotela wakho angase futhi alungise uhlelo lokulinganisa ngokusekelwe endleleni ozabela ngayo kanye nanoma yimaphi imiphumela emibi oyitholayo.

Kubalulekile ukugcina wonke ama-aphoyintimenti akho ahleliwe futhi ungalokothi uvumele iphampu yakho iphele. Ukuphelelwa umuthi kungazelelwe kungabangela izimpawu ezimbi zokuhoxiswa kanye nokubuyela kwe-spasticity enkulu.

Kufanele Ngithathe Isikhathi Esingakanani I-Baclofen (Indlela Ye-Intrathecal) ?

Abantu abaningi abazuza ku-baclofen ye-intrathecal baqhubeka nokwelashwa isikhathi eside, ngokuvamile iminyaka eminingi noma unomphela. Izimo eziyisisekelo ezibangela i-spasticity enkulu ngokuvamile azinyamalali, ngakho ukwelashwa okuqhubekayo kuvame ukudingeka.

Udokotela wakho uzoqapha impendulo yakho futhi angase alungise ukulinganisa ngokuhamba kwesikhathi, kodwa ukuyeka umuthi ngokuphelele akuvamile uma usutholile ukukhululeka. Ibhethri lephampu lihlala iminyaka engaba ngu-5-7 futhi lizodinga ukushintshwa ngokuhlinzwa lapho liphansi.

Abanye abantu bangase badinge ukuphumula ekwelashweni ngenxa yezinqubo zezokwelapha noma uma kuvela izinkinga. Udokotela wakho uzohlela ngokucophelela noma yimaphi amaholide omuthi futhi angase akushintshe okwesikhashana uye emithini yomlomo ngalezi zikhathi.

Yiziphi Imiphumela Emibi Ye-Baclofen (Indlela Ye-Intrathecal)?

Njengayo yonke imithi, i-baclofen ye-intrathecal ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle. Imiphumela emibi evame kakhulu ivame ukuba mnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ongase uyithole, ukhumbula ukuthi akubona bonke abayitholayo futhi ivame ukulawuleka:

• Ukozela noma ukuzizwa ulele emini
• Isiyezi noma ukuzizwa unovalo
• Isicanucanu noma isisu esibuhlungu
• Ikhanda
• Ubuthakathaka noma ukuzizwa ungaqini njengenjwayelo
• Ukuqunjelwa
• Ubunzima ngenkulumo noma amazwi angcolile
• Izinkinga ngokulinganisela noma ukuxhumana

Lezi zinto ezivamile zivame ukuba ngaphansi kokuphazamisa njengoba udokotela wakho elungisa umthamo wakho. Abantu abaningi bathola ukuthi izinzuzo zidlula lezi zinto ezingathí sina ezingalawuleki.

Imiphumela emibi engathi sína ayivamile kodwa idinga ukunakekelwa kwezokwelapha ngokushesha. Lokhu kufaka phakathi ukozela okukhulu lapho ungakwazi ukuhlala uvukile, ukuba nenkinga yokuphefumula, ubuthakathaka obukhulu bemisipha, noma izimpawu zokutheleleka endaweni yephampu njengobubomvu, ukuvuvukala, noma umkhuhlane.

Izinkinga ezingavamile kodwa ezingathi sína zingabandakanya ukungasebenzi kahle kwephampu, izinkinga ze-catheter, noma ukuvuza kwamanzi omgogodla. Ithimba lakho lezokwelapha lizokufundisa izimpawu zokuxwayisa okufanele uzibheke futhi linikeze imininingwane yokuxhumana eziphuthumayo.

Ubani Ongafanele Athole I-Baclofen (Indlela Ye-Intrathecal)?

Lokhu kwelashwa akulungelwe wonke umuntu, ngisho nalabo abane-spasticity enkulu. Udokotela wakho uzohlola ngokucophelela impilo yakho yonke nesimo esithile ngaphambi kokuncoma i-baclofen ye-intrathecal.

Ngeke ube ngumuntu olungile uma unezifo ezisebenzayo, izifo zokuphuma igazi, noma izimo ezithile zenhliziyo ezenza ukuhlinzwa kube yingozi. Abantu abanokucindezeleka okukhulu noma izimo zempilo yengqondo bangase badinge ukuqapha okwengeziwe ngoba i-baclofen ingathinta imizwa nokucabanga.

Lezi zimo ezilandelayo zingenza i-baclofen ye-intrathecal ingakulungeli:

• Ukutheleleka okusebenzayo kwesistimu noma izifo zesikhumba eduze nendawo yephampu
• Isifo esibi sezinso noma sesibindi
• Izifo zokuthuthumela ezingalawuleki
• Izinkinga ezinkulu zenhliziyo noma zamaphaphu ezenza ukuhlinzwa kube yingozi
• Izimo ezithile zempilo yengqondo noma ukukhubazeka kokuqonda
• Ukukhulelwa noma izinhlelo zokukhulelwa
• Ukungezwani ne-baclofen noma izingxenye zesistimu yephampu

Udokotela wakho uzobuye acabange ukuthi ungakwazi yini ukugcina ama-aphoyintimenti okulandelayo ngokwethembeka futhi uqonde ukuzibophezela okuhilelekile ekunakekelweni kwephampu. Lokhu kwelashwa kudinga ukunakekelwa kwezokwelapha okuqhubekayo nokuqapha.

Amagama Omkhiqizo we-Baclofen (Indlela Ye-Intrathecal)

Igama elivamile lomkhiqizo we-baclofen ye-intrathecal yi-Lioresal Intrathecal, eyenzelwe ngqo ukulethwa ngamasistimu amaphampu. Lesi sixazululo esingenazo izinto eziphilayo sihlukile kumaphilisi e-baclofen owaqonda ngawo.

Amasistimu amaphampu ngokwawo anamagama ahlukene emikhiqizo afana namaphampu e-SynchroMed ka-Medtronic, kodwa umuthi ongaphakathi ngokuvamile uyisithako esifanayo se-baclofen. Udokotela wakho uzochaza ukuthi yiluphi uhlelo lwepompo kanye nokugxila kwe-baclofen okusebenza kahle kakhulu ezidingweni zakho.

Ezinye izikhungo zezokwelapha zingase zisebenzise izixazululo ze-baclofen ezihlanganisiwe ezilungiselelwe ngamakhemisi akhethekile, kodwa lezi zilandela amazinga afanayo okuphepha nokusebenza kahle njengalezo ezinegama lomkhiqizo.

Ezinye izindlela ze-Baclofen (Intrathecal Route)

Uma i-baclofen ye-intrathecal ingakulungele, ezinye izinketho zokwelapha zingasiza ekuphatheni i-spasticity enzima. Udokotela wakho angase asikisele ukuzama imithamo ephezulu yezidambisi zemisipha ngomlomo kuqala, noma ukuhlanganisa imithi ehlukene ukuze uthole imiphumela engcono.

Eminye imithi ye-intrathecal efana ne-morphine noma i-clonidine ngezinye izikhathi ingasiza nge-spasticity, ikakhulukazi lapho ubuhlungu buyinkinga enkulu futhi. Ukujova kwe-Botulinum toxin kusebenza kahle kuma-muscle spasms endawo futhi kungaqondisa izindawo ezinzima.

Izindlela ezingezona zemithi zihlanganisa ukwelashwa ngokomzimba, ukwelashwa komsebenzi, kanye namadivayisi asizayo angathuthukisa ukusebenza ngisho nalapho i-spasticity isaqhubeka. Abanye abantu bayazuza ezinqubweni zokuhlinzwa ezisika izinzwa ezigxilile noma ezikhulula imisipha eqinile.

Ukwelashwa okusha njengokuvuselela umgogodla noma ukuvuselela ubuchopho obujulile kungase kube izinketho zezimo ezithile, nakuba lokhu kusafundwa ukuze kulawulwe i-spasticity.

Ingabe i-Baclofen (Intrathecal Route) ingcono kune-Oral Baclofen?

I-baclofen ye-intrathecal akudingeki ukuthi ibe "ngcono" kune-baclofen yomlomo, kodwa ingasebenza kahle kakhulu kubantu abane-spasticity eqinile abangatholanga ukukhululeka ngamaphilisi. Ukukhetha kuncike esimweni sakho esithile nokuthi imithi yomlomo isebenze kahle kangakanani kuwe.

Inzuzo enkulu yokulethwa kwe-intrathecal ukuthi inganikeza imiphumela eqinile ngemiphumela emincane emzimbeni wonke. Njengoba umuthi uqondiswa ngqo emgogodleni wakho, udinga imithamo emincane kakhulu futhi uthole ukulala noma ubuthakathaka obuncane emzimbeni wakho wonke.

Noma kunjalo, i-baclofen ye-intrathecal idinga ukuhlinzwa, ukuqokwa kwezokwelapha okuqhubekayo, futhi inezingozi ezingatholakali emithini yomlomo. Odokotela abaningi batusa ukuzama i-baclofen yomlomo neminye imithi kuqala ngaphambi kokucabangela uhlelo lwepompo.

Kubantu abane-spasticity elula kuya kweliphakathi, i-baclofen yomlomo ivame ukwanele futhi kulula kakhulu ukuyiphatha. Indlela ye-intrathecal iba yindlela ekhethwayo lapho imithi yomlomo inganikezi ukukhululeka okwanele noma ibangela imiphumela eminingi.

Imibuzo Evame Ukubuzwa Mayelana ne-Baclofen (Indlela ye-Intrathecal)

Ingabe i-Baclofen (Indlela ye-Intrathecal) iphephile kubantu abanezifo zezinso?

I-baclofen ye-Intrathecal ingaba iphephile kubantu abanezinkinga zezinso uma iqhathaniswa ne-baclofen yomlomo, kodwa isadinga ukuqapha okucophelelayo. Njengoba umuthi udlula ngohlelo lwakho lokugaya ukudla futhi usebenzisa imithamo emincane kakhulu, kuncane ukucindezela ezinso zakho.

Noma kunjalo, udokotela wakho uzodinga ukuqapha ukusebenza kwezinso zakho njalo futhi angase alungise umthamo wakho ngokuya ngokuthi izinso zakho zisebenza kahle kangakanani. Abantu abanezifo ezinzima zezinso bangase badinge ukuqapha okuningi noma ezinye izindlela zokwelapha.

Ngingenzani uma ngithola i-Baclofen eningi ngengozi?

Ukweqisa umthamo we-Baclofen ovela ku-intrathecal pump akuvamile kodwa kubi futhi kudinga ukunakekelwa kwezempilo ngokushesha. Izimpawu zokweqisa umthamo zihlanganisa ukozela okukhulu, ukuhluleka ukuphefumula, ubuthakathaka bemisipha, ukudideka, noma ukulahlekelwa ukwazi.

Uma usola ukuthi kukhona ukweqisa umthamo, shayela ku-911 noma uye egumbini eliphuthumayo eliseduze ngokushesha. Ungazami ukuzelapha noma ulinde ukubona ukuthi izimpawu ziyathuthuka yini. Ochwepheshe bezokwelapha bangahlehlisa imiphumela futhi balungise izilungiselelo zakho ze-pump.

I-pump yakho inezici zokuphepha zokuvimbela ukweqisa umthamo, kodwa izinkinga zemishini zingenzeka ngezikhathi ezithile. Yingakho ukuhlolwa kwe-pump njalo nokulandela isimiso sakho sokugcwalisa kubaluleke kakhulu.

Ngingenzani Uma I-Pump Yami Iphelelwa Umuthi?

Ungalokothi uvumele i-pump yakho iphele ngokuphelele, ngoba lokhu kungabangela izimpawu eziyingozi zokuhoxiswa okuhlanganisa ukubuyela kwe-spasticity enkulu, ukuquleka, nezinye izinkinga ezinzima. Gcina umkhondo wokuqokwa kwakho kokugcwalisa futhi uthinte udokotela wakho ngokushesha uma ucabanga ukuthi i-pump yakho ingase iphansi.

Izimpawu zokuqala zokuthi i-pump yakho ingase iphansi zihlanganisa ukubuyela kokuqina kwemisipha, ukwanda kwama-spasms, noma izimpawu obhekane nazo ngaphambi kokuqala ukwelashwa. Ungalindi ukuthi lezi zimpawu zibe zimbi ngaphambi kokufuna usizo.

Ithimba lakho lezokwelapha lizokunikeza inombolo yezimo eziphuthumayo yezinkinga eziphathelene ne-pump. Bavame ukukubona ngokushesha ukuze uthole ukugcwaliswa okuphuthumayo uma kudingeka.

Ngingayeka Nini Ukuthatha I-Baclofen (Intrathecal Route)?

Ukwiyeka i-baclofen ye-intrathecal ngokuvamile akukhuthazwa ngaphandle uma une-side effects ezinzima noma izinkinga. Izimo eziyisisekelo ezidinga lokhu kwelashwa ngokuvamile azithuthuki ngokwanele ukuze kuyekwe imithi ngokuphelele.

Uma udinga ukuyeka ngezizathu zezokwelapha, udokotela wakho uzokwehlisa kancane kancane umthamo wakho emasontweni amaningana noma izinyanga. Ukuyeka kungazelelwe kungabangela izimpawu eziyingozi zokuhoxiswa okuhlanganisa i-spasticity enkulu, ukuquleka, nezinye izinkinga ezinzima.

Abanye abantu bangase bathathe ikhefu emithini ngenxa yokuhlinzwa noma ezinye izinqubo zezokwelapha, kodwa lokhu kudinga ukuhlelwa ngokucophelela futhi kuvame ukuguqulwa okwesikhashana emithini yomlomo. Ungalokothi uyeke noma weqe imithamo ngaphandle kokuxoxa nodokotela wakho kuqala.

Ngingakwazi yini ukuthatha i-MRI Scans nge-Intrathecal Pump?

Amaphampu amaningi anamuhla e-intrathecal ahambisana ne-MRI, kodwa kuzodingeka ukuthi ulandele imithetho ethile yokuphepha. Hlala wazisa noma yimuphi umhlinzeki wezempilo ngepompo yakho ngaphambi kwanoma yiziphi izifundo zokucabanga noma izinqubo zezokwelapha.

Ipompo yakho ingase idinge ukuhlelwa okwesikhashana ngendlela ehlukile ngaphambi kwe-MRI scans, futhi kungase kudingeke ukuthi ugweme izinhlobo ezithile zamandla kazibuthe aqinile. Umkhiqizi wakho wepompo unikeza iziqondiso ezithile ezizolandela ithimba lakho lezokwelapha.

Gcina ikhadi lakho lokuhlonza ipompo nawe ngaso sonke isikhathi futhi wazise ezokuphepha zesikhumulo sezindiza, abasebenzi bezokwelapha, nanoma ubani osebenzisa imishini yezokwelapha ngedivayisi yakho efakwe.