Yini i-Baloxavir Marboxil: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Baloxavir marboxil iyimithi elwa namagciwane e-oda odokotela eyenzelwe ngqo ukwelapha amagciwane e-influenza A kanye no-B. Isebenza ngendlela ehlukile kunezinye izidakamizwa zomkhuhlane ngokuvimba i-enzyme ebalulekile edingwa amagciwane omkhuhlane ukuze azale emzimbeni wakho.

Le mithi inikeza inketho yokwelashwa ngomthamo owodwa olula wezimpawu zomkhuhlane. Ngokungafani neminye imithi elwa namagciwane edinga imithamo eminingi ezinsukwini eziningana, i-baloxavir marboxil ingathathwa kanye nje ukusiza ukunciphisa ubukhulu nobude bezimpawu zakho zomkhuhlane.

Yini i-Baloxavir Marboxil Esetshenziselwa Yona?

I-Baloxavir marboxil isetshenziswa ikakhulukazi ukwelapha i-influenza ebukhali, engahambisani nezinkinga kubantu abebe nezimpawu zomkhuhlane isikhathi esingaphezu kwamahora angama-48. Imithi isebenza kahle uma iqala ngosuku lokuqala noma lwesibili lokuzwa ukugula.

Udokotela wakho angase akubhalele le mithi uma uhlangabezana nezimpawu ezivamile zomkhuhlane njengomkhuhlane, izinhlungu emzimbeni, ikhanda elibuhlungu, ukukhathala, nezimpawu zokuphefumula. Isebenza kahle kokubili izinhlobo ze-influenza A kanye no-B, okuyizinhlobo ezivame kakhulu zomkhuhlane wesizini.

Imithi iphinde yamukelwe ukuvimbela umkhuhlane kubantu abaye bahlangana nomuntu one-influenza. Lokhu kusetshenziswa kokuvimbela, okubizwa ngokuthi i-post-exposure prophylaxis, kungasiza ukunciphisa amathuba akho okugula ngemva kokuxhumana eduze nomuntu onegciwane.

Isebenza Kanjani i-Baloxavir Marboxil?

I-Baloxavir marboxil isebenza ngokugxila ku-enzyme ethile ebizwa ngokuthi i-cap-dependent endonuclease edingwa amagciwane omkhuhlane ukuze azale. Lokhu kuyenza ihluke kwezinye izidakamizwa zomkhuhlane ezisebenza ngezindlela ezihlukene.

Cabanga ngayo njengokuvimba ithuluzi elibalulekile elisetshenziswa yigciwane ukuzikopisha. Lapho igciwane lingakwazi ukuzala ngempumelelo, amasosha akho omzimba anethuba elingcono lokulwa nokutheleleka. Lokhu kusiza ukunciphisa kokubili ubukhulu bezimpawu zakho nokuthi uzizwa isikhathi esingakanani ugula.

Umuthi uthathwa njengomuthi olungile phakathi kokwelashwa kwe-antiviral. Uyasebenza kodwa uthambile kunezinye izinketho, onamiphumela emincane eminingi kubantu abaningi. Ucwaningo lwezempilo lubonisa ukuthi lunganciphisa isikhathi somkhuhlane ngosuku olulodwa uma uthathwa kungakapheli amahora angama-48 ngemuva kokuqala kwezimpawu.

Kufanele Ngiyithathe Kanjani I-Baloxavir Marboxil?

I-Baloxavir marboxil ithathwa njengomthamo owodwa ngomlomo, okwenza kube lula kakhulu uma kuqhathaniswa neminye imithi yomkhuhlane. Umthamo oqondile uncike esisindweni sakho, futhi udokotela wakho uzonquma inani elifanele lakho.

Ungawuthatha lo muthi ngaphandle noma ngaphandle kokudla, nakuba abanye abantu bekuthola kulula esiswini sabo uma uthathwa nokudla okulula. Gwema ukuwuthatha ngemikhiqizo yobisi, iziphuzo eziqinisiwe nge-calcium, noma ama-antacid aqukethe i-aluminium, i-magnesium, noma i-calcium, ngoba lokhu kungaphazamisa ukumuncwa.

Uma udinga ukuthatha noma iyiphi yale mikhiqizo, yihlukanise okungenani ngamahora amabili ngaphambi noma ngemuva kokuthatha i-baloxavir marboxil. Amanzi ayisinqumo esingcono kakhulu sokugwinya umuthi. Qiniseka ukuthi uphuza uketshezi oluningi ngenkathi usalulama emkhuhlaneni.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Baloxavir Marboxil?

Ubuhle be-baloxavir marboxil ukuthi yakhelwe njengokwelashwa komthamo owodwa. Ngokuvamile udinga ukuyithatha kanye kuphela, ngokungafani neminye imithi yomkhuhlane edinga imithamo eminingi ezinsukwini eziningana.

Ukwelashwa kwezimpawu zomkhuhlane ezisebenzayo, umthamo owodwa ngokuvamile wanele. Uma uyithatha ukuze uvimbele ngemuva kokuchayeka kumkhuhlane, udokotela wakho angase akuchazele umthamo owodwa okufanele uthathwe kungakapheli amahora angama-48 ngemuva kokuchayeka.

Ungathathi imithamo eyengeziwe ngaphandle uma uqondiswe ngqo ngumhlinzeki wakho wezempilo. Umuthi uqhubeka usebenza ohlelweni lwakho izinsuku eziningana ngemuva komthamo owodwa, yingakho ukuthatha ngokuphindaphindiwe kungadingekile.

Yiziphi Imiphumela Eceleni Ye-Baloxavir Marboxil?

Abantu abaningi bayakwazi ukumelana kahle ne-baloxavir marboxil, kanti imiphumela emibi ngokuvamile iba mncane futhi yesikhashana. Imiphumela emibi evame kakhulu ngokuvamile ingeyokugaya ukudla futhi iyazilungisa yodwa.

Nansi imiphumela emibi evame kakhulu ongase uyithole, ukhumbula ukuthi abantu abaningi abanayo imiphumela emibi nakancane:

• Ukucasuka kwesisu noma isicanucanu
• Ukuqunjelwa
• Ukukhathala
• Isiyezi
• Ukukhathala
• Ukuncipha kwesifiso sokudla

Lezi zimpawu ngokuvamile zithambile futhi zivame ukuba nzima ukuzihlukanisa ezimpawini zomkhuhlane ngokwazo. Abantu abaningi bathola ukuthi bazizwa ngcono phakathi nosuku olulodwa noma ezimbili.

Imiphumela emibi engavamile kodwa ebucayi ingenzeka, nakuba ingavamile. Lokhu kuhlanganisa ukusabela okukhulu komzimba, okungase kubangele ubunzima bokuphefumula, ukuvuvukala kobuso noma umphimbo, noma ukusabela okukhulu kwesikhumba.

Abanye abantu babike izinguquko zemizwa noma izimpawu zokuziphatha, ikakhulukazi ezigulini ezincane. Uma wena noma othile omuhlinzayo enokuziphatha okungavamile, ukudideka, noma izinguquko zemizwa, xhumana nomhlinzeki wakho wezempilo ngokushesha.

Ubani Ongafanele Athole I-Baloxavir Marboxil?

I-Baloxavir marboxil ayifanele wonke umuntu, futhi udokotela wakho uzocabangela izici eziningana ngaphambi kokuyinika. Abantu abanezifo ezithile noma izimo zezokwelapha bangase badinge ukugwema lo muthi.

Akufanele uthathe i-baloxavir marboxil uma unokungezwani komzimba nomuthi noma yiziphi izithako zawo. Xhumana nodokotela wakho mayelana nanoma yikuphi ukusabela komzimba okwedlule emithini, ikakhulukazi ezinye izinto ezilwa namagciwane.

Ukuqapha okukhethekile kuyadingeka kumaqembu athile abantu. Abesifazane abakhulelwe nabancelisayo kufanele baxoxe ngezingozi nezinzuzo nomhlinzeki wabo wezempilo, njengoba kunedatha yokuphepha elinganiselwe yalaba bantu.

Abantu abanezinkinga ezinzima zezinso noma isibindi bangase badinge ukulungiswa komthamo noma ezinye izindlela zokwelapha. Udokotela wakho uzocabangela isimo sakho sempilo esiphelele neminye imithi oyithathayo ngaphambi kokunika i-baloxavir marboxil.

Izingane ezingaphansi kweminyaka engu-12 ngokuvamile azinikezwa lo muthi, njengoba ukuphepha nokusebenza kungakahlolwa emaqenjini eminyaka emincane. Udokotela wezingane angakwazi ukuncoma ezinye izindlela ezifanele zezingane.

Igama Lomkhiqizo le-Baloxavir Marboxil

I-Baloxavir marboxil ithengiswa ngaphansi kwegama lomkhiqizo elithi Xofluza e-United States nakwamanye amazwe amaningi. Leli gama lomkhiqizo lenziwa yi-Genentech, ilungu le-Roche Group.

I-Xofluza itholakala njengamaphilisi omlomo ngamandla ahlukene, ngokuvamile angu-20 mg no-40 mg. Amandla athile nenani lamaphilisi ozowathatha kuncike esisindweni sakho nokuthi uyayisebenzisela ukwelapha noma ukuvimbela.

Lapho uthatha umuthi wakho, qiniseka ukuthi ikhemisi likunika umkhiqizo namandla afanele. Izinhlobo ze-generic zingase zitholakale esikhathini esizayo, kodwa njengamanje, i-Xofluza ingumkhiqizo oyinhloko otholakalayo.

Ezinye izindlela ze-Baloxavir Marboxil

Eminye imithi eminingi yokulwa namagciwane iyatholakala yokwelapha umkhuhlane, ngalinye linokuzuzisa kwalo nokucatshangelwayo. Udokotela wakho angakusiza ukhethe inketho engcono kakhulu ngokusekelwe esimweni sakho esithile.

I-Tamiflu (oseltamivir) mhlawumbe ngumuthi womkhuhlane owaziwa kakhulu. Idinga ukuthathwa kabili ngosuku izinsuku ezinhlanu kodwa isetshenziswe isikhathi eside futhi inemininingwane eminingi yokuphepha. Itholakala ngesimo samaphilisi nolwelo.

I-Relenza (zanamivir) ngumuthi ongeniswa ngomoya othathwa kabili ngosuku izinsuku ezinhlanu. Kungase kube yindlela enhle uma ungakwazi ukuthatha imithi yomlomo, nakuba ingafanele abantu abanezinkinga zokuphefumula njenge-asthma.

I-Rapivab (peramivir) inikezwa njengomthamo owodwa we-intravenous ezindaweni zokunakekelwa kwezempilo. Ngokuvamile igcinelwe abantu abangakwazi ukuthatha imithi yomlomo noma abanezimpawu ezinzima zomkhuhlane ezidinga ukulaliswa esibhedlela.

Zonke lezi zindlela ezingezinye zinezidingo zesikhathi esihlukile, amaphrofayili emiphumela emibi, kanye namazinga okusebenza kahle. Umhlinzeki wakho wezempilo uzocabangela izinto ezinjengezimpawu zakho, umlando wezokwelapha, kanye nezintandokazi zomuntu siqu lapho encoma inketho engcono kakhulu.

Ingabe i-Baloxavir Marboxil ingcono kune-Tamiflu?

Kokubili i-baloxavir marboxil kanye ne-Tamiflu kuyizindlela zokwelapha umkhuhlane ezisebenzayo, kodwa ngalinye linobuhle obuhlukile obungenza elinye lifaneleke kangcono esimweni sakho esithile.

Inzuzo enkulu ye-baloxavir marboxil ukulula - udinga kuphela ukuyithatha kanye uma iqhathaniswa nokuthatha i-Tamiflu kabili ngosuku izinsuku ezinhlanu. Lokhu kungasiza ikakhulukazi uma uzizwa ugula futhi ufuna ukugwema ukukhumbula imithamo eminingi.

Ucwaningo luphakamisa ukuthi yomibili imithi inganciphisa ubude bomkhuhlane ngosuku olulodwa uma iqaliswa kungakapheli amahora angama-48 ezimpawu. Kodwa-ke, i-baloxavir marboxil ingase inciphise inani legciwane ohlelweni lwakho ngokushesha, okungenzeka ukuthi ikwenze ungatheleli ngokushesha.

I-Tamiflu itholakale isikhathi eside futhi inemininingwane yokuphepha ebanzi, ikakhulukazi kubantu besifazane abakhulelwe kanye nezingane. Itholakala futhi ngesimo esiwuketshezi, esingaba lula ukusithatha kwabanye abantu.

Imiphumela emibi ivame ukufana phakathi kwemithi emibili, nakuba abanye abantu beyibekezelela kangcono enye kunenye. Izindleko nomshwalense nakho kungahluka phakathi kwezinketho ezimbili.

Imibuzo Evame Ukubuzwa Mayelana ne-Baloxavir Marboxil

Ingabe i-Baloxavir Marboxil iphephile kubantu abanesifo sikashukela?

I-Baloxavir marboxil ngokuvamile ithathwa njengephephile kubantu abanesifo sikashukela, njengoba ingawathinti ngokuqondile amazinga kashukela egazini. Kodwa-ke, ukugula ngomkhuhlane ngezinye izikhathi kungenza ukulawula ushukela wegazi kube yinselele.

Kufanele uqhubeke nokubheka amazinga kashukela wegazi lakho eduze ngenkathi ugula futhi ululama. Umkhuhlane ngokwawo, kanye nezinguquko ekudleni nasezindleleni zokuzivocavoca, kungathinta amazinga akho e-glucose ngaphezu komuthi.

Xoxa nodokotela wakho mayelana nanoma yiziphi izinto ezikhathazayo, ikakhulukazi uma unesifo sikashukela esingalawuleki kahle noma ezinye izinkinga. Bangakunikeza isiqondiso sokulawula kokubili izimpawu zakho zomkhuhlane nokunakekelwa kwesifo sikashukela ngesikhathi sokululama.

Kufanele Ngenzeni Uma Ngisebenzisa Ngengozi I-Baloxavir Marboxil Eningi Kakhulu?

Njengoba i-baloxavir marboxil ivame ukunqunywa njengomthamo owodwa, ukweqisa ngengozi akuvamile. Kodwa-ke, uma ngengozi uthatha okuningi kunokuqondisiwe, ungesabi kodwa funa usizo lwezokwelapha.

Xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha uma uthathe okuningi kakhulu kunomthamo oqondisiwe. Bangahlola isimo sakho futhi banikeze isiqondiso esifanele ngokusekelwe kokuningi okuthathile nokuthi nini.

Izimpawu zokweqisa azisungulwanga kahle njengoba umuthi umusha, kodwa noma yiziphi izimpawu ezingavamile ngemva kokuthatha umuthi owengeziwe kufanele zihlolwe uchwepheshe wezempilo. Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ukuba wenze kanjalo.

Kufanele Ngenzeni Uma Ngedlula Umthamo We-Baloxavir Marboxil?

Lo mbuzo ngokuvamile awusebenzi ku-baloxavir marboxil njengoba yakhelwe njengokwelashwa komthamo owodwa. Uthatha kanye, futhi lokho kuvame ukuba konke okudingekayo ekwelapheni izimpawu zomkhuhlane.

Uma ukhohlwe ukuthatha umthamo wakho oqondisiwe futhi sekudlule amahora angaphezu kwama-48 kusukela ekuqaleni kwezimpawu zakho zomkhuhlane, xhumana nodokotela wakho. Umuthi usebenza kahle kakhulu uma uthathwa ezinsukwini ezimbili zokuqala zokugula.

Udokotela wakho angase ancome ukuyithatha ngisho noma usudlule iwindi lama-48-hour, noma bangase baphakamise ezinye izindlela zokwelapha noma ukunakekelwa okusekelayo kuye ngezimpawu zakho nokuthi uzizwa kanjani.

Ngingayeka Nini Ukuthatha I-Baloxavir Marboxil?

Akudingeki ukhathazeke ngokuyeka i-baloxavir marboxil njengoba kuyindlela yokwelapha ngomthamo owodwa. Uma usuthatha lowo mthamo owodwa, usuqedile inkambo ephelele yokwelashwa.

Umuthi uqhubeka nokusebenza emzimbeni wakho izinsuku eziningana ngemuva kokuwuthatha, yingakho kungadingeki imithamo eyengeziwe. Kufanele uqale ukuzizwa ungcono phakathi nosuku olulodwa noma ezimbili njengoba umuthi uqala ukusebenza.

Uma izimpawu zakho ziba zimbi kakhulu noma zingathuthuki ngemuva kwezinsuku ezimbalwa, xhumana nomhlinzeki wakho wezempilo. Lokhu kungase kubonise izinkinga noma ezinye izifo ezidinga ukwelashwa okwengeziwe.

Ngingawuthatha i-Baloxavir Marboxil neminye imithi?

I-Baloxavir marboxil ingasebenzisana neminye imithi, ngakho-ke kubalulekile ukutshela umhlinzeki wakho wezempilo ngakho konke okuthathayo, okuhlanganisa imithi etholakala ngaphandle kwe-oda kanye nezithasiselo.

Imikhiqizo equkethe i-calcium, i-magnesium, noma i-aluminum ingaphazamisa ukumuncwa, ngakho-ke gwema ukuthatha ama-antacids, izithasiselo ze-calcium, noma ukudla okuqinisiwe kungakapheli amahora amabili ngemuva komthamo wakho. Lokhu kuhlanganisa amavithamini amaningi amaningi neminye imikhiqizo yobisi.

Imithi eminingi engeminye ingathathwa ngokuphepha nge-baloxavir marboxil, kodwa usokhemisi wakho noma umhlinzeki wezempilo angahlola noma yikuphi ukusebenzisana okungaba khona nemithi yakho ethile. Hlala ubuza ngaphambi kokuhlanganisa noma iyiphi imithi emisha, ngisho noma ibonakala ingahlobene nokwelashwa kwegciwane lomkhuhlane.