Yini i-Bebtelovimab: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Bebtelovimab yimithi eyenziwe ngama-antibody e-monoclonal eyenzelwe ngqo ukusiza umzimba wakho ukulwa ne-COVID-19. Cabanga ngayo njengomuthi oqondiswe ngqo onikeza amasosha akho omzimba usizo olwengeziwe lapho elwa negciwane.

Lo muthi wenzelwe ukwelapha i-COVID-19 emnene kuya kokulingene kubantu abadala nezingane ezingozi enkulu yokugula kanzima. Isebenza ngokuvimba igciwane ukuthi lingangeni emangqamuzaneni akho, okusiza ukunciphisa ubukhulu bezimpawu zakho futhi okungenzeka ukuthi ivimbele ukulaliswa esibhedlela.

Yini i-Bebtelovimab?

I-Bebtelovimab iyi-antibody eyenziwe e-laboratory elingisa impendulo yomzimba yakho yemvelo ku-COVID-19. Iyingxenye yohlobo lwemithi ebizwa ngokuthi ama-antibody e-monoclonal, enzelwe ukuthi aqondise izingxenye ezithile zegciwane.

Lo muthi wadalwa ososayensi abafunda ukuthi amasosha ethu omzimba alwa kanjani ngokwemvelo ne-COVID-19. Bakhomba ama-antibody asebenza kahle kakhulu futhi bawadala kabusha endaweni ye-laboratory. Lokhu kuvumela odokotela ukuthi bakunikeze umthamo ogxilile walezi zinhlobo zamaprotheni okuvikela lapho umzimba wakho udinga ukwesekwa okwengeziwe.

Ngokungafani neminye imithi ye-COVID-19, i-bebtelovimab inikezwa njengomjovo owodwa emthanjeni wakho. Le ndlela eqondiswe ngqo isho ukuthi umuthi ungaqala ukusebenza ngokushesha egazini lakho ukusiza ukulwa nokutheleleka.

Isetshenziselwani i-Bebtelovimab?

I-Bebtelovimab isetshenziselwa ukwelapha i-COVID-19 emnene kuya kokulingene kubantu abasengozini enkulu yokugula kanzima. Udokotela wakho angase ancome lo muthi uma usanda kutholakala ukuthi unayo i-COVID-19 futhi unezici ezithile eziyingozi.

Lo muthi ulusizo ikakhulukazi kubantu abanezimo zempilo ezingaphansi ezibenza babe sengozini enkulu ye-COVID-19 kanzima. Lezi zimo zihlanganisa isifo sikashukela, isifo senhliziyo, izinkinga zamaphaphu, isifo sezinso, noma amasosha omzimba abuthaka ngenxa yeminye imithi noma ukwelashwa.

Iphinde isetshenziselwe abantu abaneminyaka engaphezu kwengama-65 ubudala, njengoba iminyaka ngokwayo ikhuphula ingozi yezinkinga ezinzima ze-COVID-19. Ukwelashwa kusebenza kahle uma kunikezwa ekuqaleni kokugula kwakho, ngokuvamile ezinsukwini ezimbalwa zokuqala zokuqala kwezimpawu.

Umhlinzeki wakho wezempilo uzocabangela izici zakho eziyingozi kanye nesimo sakho sempilo yamanje ukuze anqume ukuthi i-bebtelovimab ilungele yini wena. Umgomo uwukuvimbela izimpawu zakho ze-COVID-19 ukuthi zingabi zimbi kangangokuthi zidinge ukulaliswa esibhedlela.

Isebenza Kanjani I-Bebtelovimab?

I-Bebtelovimab isebenza ngokunamathela emaprotheni athile ngaphezulu kwe-COVID-19 igciwane, ivimbele ukuthi lingangeni emangqamuzaneni akho anempilo. Lokhu kuthathwa njengokwelashwa okuqinile okulinganiselwe okungathinta kakhulu ikhono legciwane lokusabalala emzimbeni wakho wonke.

Lapho igciwane lizama ukuthelela amaseli akho, lisebenzisa amaprotheni e-spike ukunamathela nokungena. I-Bebtelovimab isebenza njengenduku, emboza lawa maprotheni e-spike ukuze igciwane lingakwazi ukuqeda ukuhlasela kwalo. Lokhu kunika amasosha akho omzimba isikhathi sokuthi akhe impendulo eqinile.

Umuthi awelaphi i-COVID-19 ngokushesha, kodwa ungasiza ukunciphisa ubunzima nobude bezimpawu zakho. Abantu abaningi baqala ukuzizwa ngcono ezinsukwini ezimbalwa kuya evikini elilodwa ngemva kokuthola ukwelashwa, nakuba izimpendulo zomuntu ngamunye zingahluka.

Ngenxa yokuthi i-bebtelovimab iqondise ngqo igciwane, ingasebenza ngempumelelo ngisho noma amasosha akho omzimba ekhubazekile. Lokhu kuyenza ibaluleke kubantu abangase bangakwazi ukulwa nokutheleleka ngempumelelo ngokwabo.

Kufanele Ngiyithathe Kanjani I-Bebtelovimab?

I-Bebtelovimab inikezwa njengomjovo owodwa we-intravenous, okusho ukuthi ihanjiswa ngqo egazini lakho ngeshubhu elincane engalweni yakho. Uzothola lokhu kwelashwa esibhedlela, emtholampilo, noma esikhungweni sokufaka lapho ochwepheshe bezempilo bengakuqapha ngokuphepha.

Ngaphambi kokwelashwa kwakho, akudingeki ukuthi ulandele noma yimiphi imikhawulo ekhethekile yokudla. Ungadla futhi uphuze ngokujwayelekile, nakuba kuwukuhlakanipha ukuba nesidlo esilula ngaphambi kwalokho ukusiza ekuvikeleni isicanucanu. Qiniseka ukuthi unamanzi ngokwanele ngokuphuza amanzi amaningi emahoreni ngaphambi kokuqokwa kwakho.

Ukunikezwa kwangempela kuthatha imizuzu engaba ngu-30, futhi kuzodingeka uhlale ukuze ubukwe okungenani ihora ngemva kwalokho. Lesi sikhathi sokubheka sibalulekile ngoba abahlinzeki bezempilo bafuna ukuqiniseka ukuthi awunazo izimpendulo eziqondile emuthini.

Ngesikhathi sokunikezwa, cishe uzohlala esihlalweni esinethezekile ngenkathi umuthi ugeleza kancane emthanjeni wakho. Abantu abaningi bathola ukuthi inqubo iyamukeleka kakhulu, ifana nokuthola uketshezi lwe-IV noma ezinye izindlela zokwelapha ezivamile.

Kufanele Ngithathe Isikhathi Esingakanani I-Bebtelovimab?

I-Bebtelovimab ivamise ukunikezwa njengomthamo owodwa, ngakho-ke ngeke kudingeke ukuthi uyithathe isikhathi eside. Lokhu kwelashwa okukodwa kuklanyelwe ukunikeza umzimba wakho ngama-antibody owadingayo ukuze ulwe ne-COVID-19 ngempumelelo.

Imiphumela evikelayo ye-bebtelovimab ingahlala amasonto amaningana ohlelweni lwakho. Kodwa-ke, umuthi usebenza kahle kakhulu uma unikezwa ekuqaleni kokugula kwakho, ngokufanelekile ezinsukwini ezinhlanu zokuqala zokuqala kwezimpawu noma imiphumela yokuhlolwa okuhle.

Ngeke kudingeke ukuthi ubuyele emithini eyengeziwe ngaphandle uma udokotela wakho ekuncoma ngokuqondile ngokuya ngezimo zakho ngazinye. Abantu abaningi bathola inzuzo ephelele ekwelashweni okukodwa, futhi izimpawu zabo ziqala ukuthuthuka ezinsukwini ezimbalwa.

Ngemva kokuthola i-bebtelovimab, kufanele uqhubeke nokulandela ezinye izincomo zomnikezeli wakho wezempilo zokuphatha i-COVID-19, okuhlanganisa ukuphumula, ukuthatha amanzi, nokubheka izimpawu zakho nganoma yiziphi izinguquko.

Yiziphi Imiphumela Eceleni Ye-Bebtelovimab?

Abantu abaningi bayamukela kahle i-bebtelovimab, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela emibi engathi sína ayivamile, futhi iningi lezimpawu zithambile futhi zidlula ngokushesha.

Nawa amanye emiphumela emibi evame kakhulu ongase uyithole, ukhumbula ukuthi abantu abaningi ababi nayo imiphumela emibi nakancane:

• Isicanucanu esithambile noma isisu esibuhlungu
• Ukucabana kwekhanda
• Ukukhathala noma ukuzizwa ukhathele
• Isiyezi
• Ubuhlungu obuthambile noma ukuvuvukala endaweni yokujova
• Ukuqaqamba kwemisipha

Le miphumela emibi ejwayelekile ivame ukuzixazulula yona ngosuku olulodwa noma ezimbili futhi ivame ukulawuleka ngokuphumula kanye nemithi yokwelapha ubuhlungu etholakala ngaphandle kwemvume kadokotela uma kudingeka.

Imiphumela emibi engathi sína kodwa engavamile ingabandakanya ukusabela komzimba okungalungile, yingakho uzoqashwa eduze ngesikhathi nangemva kokufakwa komuthi. Izimpawu zokusabela komzimba okungalungile zingabandakanya:

• Ukuphefumula kanzima noma ukukhwehlela
• Ukuvuvukala ebusweni bakho, ezindebeni, olimini, noma emqaleni
• Ukuqubuka okukhulu noma ama-hives
• Ukushaya kwenhliziyo okusheshayo
• Isiyezi esikhulu noma ukuquleka

Uma uhlangabezana nanoma yiziphi lezi zimpawu ezingathi sína, abasebenzi bezokwelapha bazotholakala ngokushesha ukukusiza. Yingakho kanye isikhathi sokubheka ngemva kokufakwa komuthi sibaluleke kangaka.

Ngokuvamile, abanye abantu bangase bahlangabezane nokusabela okuhlobene nokufakwa komuthi ngesikhathi sokwelashwa uqobo. Lokhu kungabandakanya amakhaza, umkhuhlane, noma izinguquko emfutheni wegazi. Abahlinzeki bezempilo baqeqeshwe ukubona nokulawula lezi zimpawu ngokushesha uma zenzeka.

Ubani Ongafanele Athole I-Bebtelovimab?

I-Bebtelovimab ayifanele wonke umuntu, futhi umhlinzeki wakho wezempilo uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuncoma lokhu kwelashwa. Okubaluleke kakhulu, akufanele uthole i-bebtelovimab uma wake waba nokusabela okukhulu komzimba okungalungile kulo muthi noma izithako zawo esikhathini esidlule.

Abantu abalaliswe esibhedlela njengamanje ngenxa ye-COVID-19 noma abadinga ukwelashwa nge-oxygen ngokuvamile ngeke bathole i-bebtelovimab, njengoba yenzelwe izigaba zokuqala zesifo. Uma izimpawu zakho seziqhubeke zaba yisifo esibi, ezinye izindlela zokwelapha zingase zifaneleke kakhulu.

Abantu abathile badinga ukucatshangelwa okwengeziwe ngaphambi kokuthola lokhu kwelashwa, nakuba bengase babe ngabakhethekayo ngokuqapha ngokucophelela:

• Abantu abanesifo esibi sezinso
• Labo abanezinkinga ezinkulu zesibindi
• Abantu abanomlando wokungezwani komzimba okukhulu emithini
• Abantu abathatha izinciphisi zegazi noma abanezinkinga zokopha
• Labo abanezimo ezithile ze-autoimmune

Umhlinzeki wakho wezempilo uzoqondanisa izinzuzo ezingaba khona nezingozi ezithile ngokusekelwe esimweni sakho sempilo esithile.

Abesifazane abakhulelwe nabancelisayo ngokuvamile bangathola i-bebtelovimab uma izinzuzo zidlula izingozi, kodwa lesi sinqumo kufanele senziwe ngaso sonke isikhathi ngokubonisana nomhlinzeki wakho wezempilo. Umuthi awukacwaningwa kabanzi ekukhulelweni, ngakho udokotela wakho uzoqaphela izimo zakho ngazinye ngokucophelela.

Izingane ezingaphansi kweminyaka eyi-12 noma labo abalinganisa ngaphansi kwama-kilogramu angama-40 ngokuvamile abatholi i-bebtelovimab, njengoba ingakacwaningwa ngokwanele kulaba bantu.

Amagama Omkhiqizo we-Bebtelovimab

I-Bebtelovimab itholakala ngaphansi kwegama lomkhiqizo elithi Bebtelovimab-mthb, elikhiqizwa yi-Eli Lilly and Company. Leli njengamanje igama eliyinhloko lomkhiqizo ozohlangana nalo lapho uxoxa ngalo muthi nomhlinzeki wakho wezempilo.

Ngokungafani neminye imithi enamagama amaningi omkhiqizo, i-bebtelovimab intsha futhi yaziwa kakhulu ngegama layo elivamile. Lapho uhlela ukwelashwa kwakho noma ukuxoxa ngakho nabasebenzi bezokwelapha, ungalibiza ngokuthi "bebtelovimab" futhi bazokwazi kahle ukuthi usho ukuthini.

Ezinye izikhungo zezokwelapha zingase zibhekisele kuyo njengengxenye yezindlela zabo zokwelapha "ngama-antibody e-monoclonal" noma "ama-therapeutics e-COVID-19," kodwa igama lomuthi eliqondile lihlala lifana kuzilungiselelo ezahlukene zokunakekelwa kwezempilo.

Ezinye izindlela zokwelapha i-Bebtelovimab

Kukhona ezinye izindlela zokwelapha i-COVID-19, kuye ngesimo sakho esithile kanye nezinto eziyingozi. Umhlinzeki wakho wokunakekelwa kwezempilo uzosiza ekutholeni ukuthi iyiphi inketho engasebenza kahle kuwe ngokusekelwe ezimweni zakho.

Ezinye izindlela zokwelapha ngama-antibody e-monoclonal ebesetshenziswa i-COVID-19 zihlanganisa i-sotrovimab ne-tixagevimab-cilgavimab, nakuba ukutholakala nokusebenza kungahluka kuye ngezinhlobo ezihambayo zegciwane. Ngayinye yalezi isebenza ngendlela efana ne-bebtelovimab kodwa ingase ibe namaphrofayili ahlukene okusebenza kahle.

Imithi yomlomo ye-antiviral efana ne-Paxlovid (nirmatrelvir-ritonavir) ne-molnupiravir inikeza enye indlela yokwelapha. Lawa maphilisi angathathwa ekhaya futhi asebenze ngokuphazamisa ikhono legciwane lokuzala emzimbeni wakho.

Kubantu abangakwazi ukuthatha noma abangaphenduli kahle kulezi zindlela zokwelapha ezithile, ukunakekelwa okusekelayo kuhlala kubalulekile. Lokhu kuhlanganisa ukuphumula, ukugcinwa kwamanzi emzimbeni, ukuphathwa komkhuhlane, nokuqapha eduze izimpawu nodokotela wakho.

Inketho yokwelapha engcono kakhulu incike ezintweni ezinjengobudala bakho, izimo zempilo ezingaphansi, eminye imithi oyithathayo, nokuthi uqala nini ukufuna ukunakekelwa uma ugula. Umhlinzeki wakho wokunakekelwa kwezempilo uzocabangela zonke lezi zinto lapho encoma inketho efanele kakhulu kuwe.

Ingabe i-Bebtelovimab ingcono kune-Paxlovid?

Kokubili i-bebtelovimab ne-Paxlovid ziyizindlela zokwelapha eziphumelelayo ze-COVID-19, kodwa zisebenza ngezindlela ezihlukene futhi zingase zifaneleke kangcono kubantu abahlukene. Ukukhetha phakathi kwazo kuvame ukuncika esimweni sakho sempilo kunokuthi esisodwa sibe ngcono kunomunye.

I-Bebtelovimab inikeza inzuzo yokuba ukwelashwa okukodwa okuthola endaweni yokunakekelwa kwezempilo, okusho ukuthi akudingeki ukhumbule ukuthatha imithamo eminingi ekhaya. Lokhu kungasiza ikakhulukazi uma uzizwa ungazizwa kahle noma unzima ukulandela imithi.

I-Paxlovid, ngakolunye uhlangothi, ithathwa njengamaphilisi ekhaya izinsuku eziyisihlanu, okuyinto abanye abantu abayithandayo ngoba akudingeki bahambe baye endaweni yokunakekelwa kwezempilo. Kodwa-ke, i-Paxlovid ingasebenzisana neminye imithi eminingi, okungenzeka ukuthi ayifanele abanye abantu.

Umhlinzeki wakho wezempilo uzocabangela izinto ezinjengeminye imithi yakho, ukusebenza kwezinso, nezintandokazi zomuntu siqu lapho ekusiza ukuthi ukhethe phakathi kwalezi zinketho. Zombili lezi zindlela zokwelapha zisebenza kahle kakhulu uma ziqala ekuqaleni kokugula kwakho, ngakho isikhathi sokuxilongwa kwakho singase sithonye nesinqumo.

Abanye abantu bangase babe ngabazali abangcono be-bebtelovimab uma benokusebenzisana kwemithi okubavimbela ukuthi bangathathi i-Paxlovid ngokuphepha. Abanye bangase bakhethe ukulula kokuthatha amaphilisi ekhaya uma bengabazali abafanelekayo bokwelashwa ngomlomo.

Imibuzo Evame Ukubuzwa Mayelana ne-Bebtelovimab

Ingabe i-Bebtelovimab iphephile kubantu abanesifo sikashukela?

Yebo, i-bebtelovimab ngokuvamile iphephile kubantu abanesifo sikashukela, futhi empeleni, isifo sikashukela singesinye sezimo ezingase zikwenze ube ngumuntu ofanelekayo kulokhu kwelashwa. Abantu abanesifo sikashukela basengozini enkulu ye-COVID-19 enzima, ngakho izinzuzo ze-bebtelovimab zivame ukwedlula izingozi.

Umuthi awuthinti ngokuqondile amazinga kashukela egazini, kodwa ukugula nge-COVID-19 ngezinye izikhathi kungenza ukuphathwa kwesifo sikashukela kube yinselele enkulu. Umhlinzeki wakho wezempilo uzokuqapha ngokucophelela futhi angase ancome ukuthi uhlole ushukela wakho wegazi kaningi ngenkathi ululama ku-COVID-19.

Uma uthatha imithi yesifo sikashukela, qhubeka uyithatha njengoba unjengoba uyalelwe ngaphandle uma udokotela wakho ekweluleka ngenye indlela. Ukwelashwa kwe-bebtelovimab ngokwako akufanele kuphazamise inqubo yakho yokulawula isifo sikashukela.

Kufanele Ngenzeni Uma Ngamukela Ngengozi I-Bebtelovimab Eningi Kakhulu?

Njengoba i-bebtelovimab inikezwa ochwepheshe bezempilo abaqeqeshiwe endaweni elawulwayo, ukweqisa ngengozi akuvamile kakhulu. Umuthi ulinganiswa ngokucophelela futhi unikezwa ngokulandela imithetho eqinile ukuqinisekisa ukuthi uthola umthamo ofanele.

Uma ukhathazekile ngokuthola umuthi omningi kakhulu, khumbula ukuthi uzoqashwa eduze ngesikhathi nangemva kokufakwa kwakho. Abahlinzeki bezempilo baqeqeshwe ukubona noma yiziphi izindlela ezingavamile futhi bangaphendula ngokushesha uma kudingeka.

Isimo somthamo owodwa we-bebtelovimab futhi sisho ukuthi akukho ngozi yokuthatha ngengozi imithamo eyengeziwe ekhaya, ngokungafani nemithi yomlomo. Ithimba lakho lezempilo lizoqinisekisa ukuthi uthola inani eliqondile lomzimba wakho nempilo yakho.

Kufanele Ngenzeni Uma Ngiphuthelwa Ukuqokwa Kwami ​​Kwe-Bebtelovimab?

Uma uphuthelwa ukuqokwa kwakho kwe-bebtelovimab okuhleliwe, xhumana nomhlinzeki wakho wezempilo ngokushesha ngangokunokwenzeka ukuze uhlele kabusha. Isikhathi sibalulekile ngalesi sithuthukisi, njengoba sisebenza kahle kakhulu uma sinikezwa ekuqaleni kokugula kwakho kwe-COVID-19.

Ungesabi uma uphuthelwa ukuqokwa kwakho ngosuku noma ezimbili. Ngenkathi ukwelashwa kwangaphambi kwesikhathi kulungile, ungase usazuza ku-bebtelovimab uma kungakapheli ngaphezu kwesonto kusukela ngesikhathi izimpawu zakho ziqala noma uhlolwe ukuthi unayo.

Umhlinzeki wakho wezempilo uzohlola ukuthi usengumuntu olungile wokwelashwa ngokusekelwe ekutheni ugule isikhathi esingakanani nezimpawu zakho zamanje. Bangase batusa i-bebtelovimab noma baphakamise ezinye izindlela zokwelapha kuye ngesimo sakho.

Ngingayeka nini ukukhathazeka nge-COVID-19 ngemva kokuthola i-Bebtelovimab?

I-Bebtelovimab ingasiza ekunciphiseni ubukhulu bezimpawu zakho ze-COVID-19, kodwa kufanele uqhubeke nokulandela izinyathelo zokuphepha ezijwayelekile ze-COVID-19 uze ungabe usatheleleka. Lokhu ngokuvamile kusho ukuzihlukanisa uze ungabi nasithuthumeleli amahora angu-24 futhi izimpawu zakho zithuthuke.

Abantu abaningi bangabuyela emisebenzini yabo ejwayelekile cishe ezinsukwini eziyi-5-10 ngemuva kokuqala kwezimpawu zabo, kuye ngokuthi bazizwa kanjani. Kodwa-ke, kufanele usalandela izincomo eziqondile zomnikezi wakho wezempilo mayelana nokuthi kuphephile nini ukuqeda ukuzihlukanisa.

Qhubeka nokubheka izimpawu zakho ngisho nangemva kokuthola i-bebtelovimab. Ngenkathi ukwelashwa kungasiza ekuvikeleni ukugula okukhulu, kufanele usaxhumane nomnikezi wakho wezempilo uma uba nezimpawu ezikhathazayo njengobunzima bokuphefumula, ubuhlungu obuqhubekayo besifuba, noma ukudideka.

Ngingakwazi Ukugonywa Ngemuva Kokuthola I-Bebtelovimab?

Yebo, ungafanele futhi kufanele ugonywe ngokumelene ne-COVID-19 ngemuva kokuthola i-bebtelovimab, kodwa isikhathi sibalulekile. Ochwepheshe abaningi batusa ukulinda okungenani izinsuku ezingama-90 ngemuva kokwelashwa kwakho nge-bebtelovimab ngaphambi kokuthola umgomo we-COVID-19 noma i-booster.

Lesi sikhathi sokulinda siqinisekisa ukuthi ama-antibody avela ku-bebtelovimab awaphazamisi ikhono lomzimba wakho lokwakha ukuzivikela emgomweni. Umhlinzeki wakho wezempilo angakunikeza isiqondiso esiqondile mayelana nesikhathi esingcono kakhulu sokugonywa kwakho.

Khumbula ukuthi i-bebtelovimab inikeza ukuvikelwa kwesikhashana, ngenkathi imigomo isiza amasosha akho omzimba ukwakha ukuzivikela okuhlala isikhathi eside. Zombili lezi zindlela zokwelapha zisebenza ndawonye njengengxenye yendlela ebanzi yokuzivikela ku-COVID-19.