Ukuhlinzeka nge-intravenous (indlela ye-intravenous)
Imikhiqizo etholakalayo
Zynteglo
Mayelana naleli khambi
I-Betibeglogene autotemcel injection isetyenziselwa ukwelapha i-beta thalassemia kubantu abadinga ukuthola igazi elibomvu (RBC) njalo. Lolu lwelapha kufanele lunikezwe kuphela ngudokotela wakho noma ngaphansi kokunakekelwa kwakhe okuqondile. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucatshangeni kokusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizoletha. Lo ngumqulu uzowenza wena nodokotela wakho. Kulo muthi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqondile noma oluhambelanayo lolu lwemi thi noma eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lokulimala, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongaphandle kwesikripthi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela yokubetha i-betibeglogene autotemcel injection kubantwana abaneminyaka engaphansi kwengu-4. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ebuhlotsheni bobudala nemiphumela yokubetha i-betibeglogene autotemcel injection azikwenzelwanga kubantu abadala. Ayikho izifundo ezifanele kwabesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswa ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthola le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile ayinconywa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma zombili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla ngoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba ngezinye izimithi kungabangela ukuhlangana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Udokotela noma omunye ochwepheshe bezempilo oqeqeshwe ngokucophelela uzokunika le miyekezo esibhedlela. Inikezwa ngenhlanzi ebekwe emithanjeni. Le miyekezo kufanele inikezwe kancane, ngakho-ke i-IV yakho kufanele ihlale isikhathi esingaphansi kwamahora angu-4. Le miyekezo iza nephephapheshe eliqukethe ulwazi lwabaguli. Funda futhi ulandele lezi zinkomba ngokucophelela. Buza udokotela wakho noma umthengisi wemithi uma unemibuzo. Ungase futhi uthole ezinye izidakamizwa (isib. imithi yomdlavuza) ngaphambi kokuthola le miyekezo. Le miyekezo yenziwe ngokukhethekile kumuntu ngamunye, usebenzisa amangqamuzana egazi lomguli. Udokotela wakho uzoqoqa igazi lakho ngenqubo ebizwa ngokuthi ukunyakaza kanye ne-apheresis. Xoxa nodokotela wakho uma ukhathazekile ngalokhu. Udokotela wakho uzofuna futhi ukuthi uhlale esibhedlela noma esikhungweni okungenani amasonto angu-3 kuya kwangu-6 ngemuva kokufakwa kwakho. Ungasebenzisi i-hydroxyurea noma imithi yokwelapha i-HIV okungenani inyanga eyodwa ngaphambi kokuba wenze inqubo yokuqoqa igazi lakho. Ungasebenzisi abaphangi be-iron okungenani izinsuku eziyi-7 ngaphambi kokuthola imithi yomdlavuza futhi izinyanga eziyi-6 ngemuva kokuthola le miyekezo.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.