Yini i-Biperiden: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Biperiden iyimithi esiza ukulawula izinkinga zokunyakaza ezibangelwa imithi ethile yezifo zengqondo noma izimo zemizwa. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-anticholinergics, asebenza ngokuvimba izimpawu zemizwa ezithile ebuchosheni bakho ezingabangela ukunyakaza kwemisipha okungafuneki, ukuqina, noma ukuthuthumela.

Uma unikezwe i-biperiden, kungenzeka ukuthi ubhekene nezinkinga zokunyakaza ezibangelwa imithi noma isimo esifana nesifo sikaParkinson. Le mithi emnene kodwa esebenzayo ingasiza ukubuyisela induduzo yakho nokuhamba lapho ezinye izindlela zokwelapha zidalile imiphumela eceleni eyinselele.

Yini i-Biperiden Esetshenziselwa Yona?

I-Biperiden ikakhulukazi iphatha izinkinga zokunyakaza ezibangelwa imithi ye-antipsychotic. Uma uthatha imithi ethile yezifo zengqondo, ngezinye izikhathi ingadala ukunyakaza kwemisipha okungahleliwe, ukuqina okukhulu, noma ukuthuthumela okuphazamisa impilo yansuku zonke.

Udokotela wakho angase akubhalele i-biperiden uma uhlangabezana nezimpawu ze-extrapyramidal ezivela emithini efana ne-haloperidol, i-chlorpromazine, noma ezinye izidakamizwa ze-antipsychotics. Lezi zimpawu zingabandakanya ukuqina kwemisipha, ukungazinzi, noma ukunyakaza okuphindaphindayo okuzizwa kungaphezu kokulawula kwakho.

Ngaphezu kwalokho, i-biperiden isiza ukuphatha izimpawu zesifo sikaParkinson, ikakhulukazi ukuthuthumela nokuqina kwemisipha. Ingasiza futhi ekwelapheni i-parkinsonism ebangwa yizidakamizwa, elingisa isifo sikaParkinson kodwa esivela emiphumeleni emibi yemithi kunokuba isifo uqobo.

Kwezinye izimo, odokotela babhala i-biperiden ye-dystonia, isimo esibangela ukuncipha kwemisipha okungahleliwe. Le mithi inganikeza impumuzo lapho imisipha incipha ngobuhlungu noma idala ukuma okungajwayelekile.

Isebenza Kanjani i-Biperiden?

I-Biperiden isebenza ngokuvimba izamukeli ze-acetylcholine ebuchosheni bakho. I-Acetylcholine iyikhemikhali ethumela imiyalezo esiza ukulawula ukunyakaza kwemisipha, futhi lapho kunomsebenzi omningi ovela kule khemikhali, kungadala izinkinga zokunyakaza ozibhekanayo.

Cabanga ngobuchopho bakho njengobunokulinganisela okuyinkimbinkimbi phakathi kwamasignali ahlukene amakhemikhali. Lapho imithi elwa nokucindezeleka ivimba i-dopamine (elinye ikhemikhali ebuchosheni), kungashintsha lokhu kulinganisela futhi kubangele i-acetylcholine ukuthi ibe nomsebenzi omningi. I-Biperiden isiza ukubuyisela lokhu kulinganisela ngokunciphisa imiphumela ye-acetylcholine.

Lo muthi ubhekwa njengomuthi onamandla ngokulinganisela futhi ngokuvamile usebenza phakathi kwemizuzu engama-30 kuya emahoreni amabili ngemuva kokuwuthatha. Imiphumela ingahlala amahora ayi-6 kuya kwayi-8, yingakho abantu abaningi bewuthatha izikhathi ezi-2 kuya kwezi-3 ngosuku.

Ngokungafani neminye imithi enamandla, i-biperiden inikeza usizo oluqondiwe ngaphandle kokuvala ngokuphelele izinhlelo zomzimba wakho zokulawula ukunyakaza kwemvelo. Lokhu kuyenza isebenze ngenkathi ivumela ukusebenza kwemisipha yakho okuvamile ukuthi kuqhubeke.

Kufanele Ngiyithathe Kanjani I-Biperiden?

Thatha i-biperiden ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile izikhathi ezi-2 kuya kwezi-3 ngosuku ngaphandle kokudla noma ngaphandle kokudla. Ungayithatha ngamanzi, ubisi, noma ijusi, noma yini ezizwa ikhululekile esiswini sakho.

Uma uhlangabezana nokuphazamiseka kwesisu, ukuthatha i-biperiden nokudla noma ubisi kungasiza ukunciphisa ukucasuka. Ukudla okulula kusebenza kahle, yize ungasidingi ukudla okuningi. Ama-crackers, isinkwa esosiwe, noma iyogathi ziyizinketho ezimnene ezingasiza ukuvikela isisu sakho.

Zama ukuthatha imithamo yakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo ohlelweni lwakho. Lokhu kuvumelana kusiza ukuvimbela izimpawu zokuphuma futhi kwenza umuthi usebenze kahle.

Gwinya amaphilisi wonke ngamanzi amaningi. Ungawachotshozi, uwahlafune, noma uwaqhekeze ngaphandle kokuthi udokotela wakho akucele ngqo ukuba wenze njalo, ngoba lokhu kungathinta ukuthi umuthi usebenza kanjani.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Biperiden?

Isikhathi sokwelashwa nge-biperiden sincike kulokho okubangela izinkinga zakho zokunyakaza. Uma uyithatha ngenxa yezimpawu ezibangelwa imithi, ungase uyidinge kuphela ngenkathi usebenzisa umuthi obangela lezo zimpawu.

Ezikhathini eziphuthumayo zokuphazamiseka kokunyakaza, ukwelashwa kungase kuthathe izinsuku ezimbalwa kuya emavikini ambalwa. Udokotela wakho uzoqapha izimpawu zakho futhi alungise ubude besikhathi ngokuya ngendlela ozosabela ngayo nokuthi imbangela eyinhloko iyaxazululeka yini.

Abanye abantu abanesifo sikaParkinson noma izimo ezingamahlalakhona bangase badinge i-biperiden isikhathi eside. Kodwa-ke, odokotela bavame ukuzama ukusebenzisa isikhathi sokwelashwa esifushane esisebenzayo ukuze banciphise imiphumela engemihle engase ibe khona.

Ungayeki ukuthatha i-biperiden ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ngokuphazima kweso kungabangela izimpawu zokuhoxisa noma kuvumele izinkinga zakho zokunyakaza zokuqala ukuthi zibuye ngendlela enzima kakhulu.

Yini Imiphumela Esemqoka Ye-Biperiden?

Abantu abaningi bayayibekezelela i-biperiden kahle, kodwa njengayo yonke imithi, ingabangela imiphumela engemihle. Ukuqonda ukuthi yini ongayilindela kungakusiza ukuthi uzizwe uqiniseka kakhulu ngemithi yakho.

Imiphumela ejwayelekile ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela imithi:

• Umlomo owomile (ovamile kakhulu)
• Ukozela noma isiyezi
• Ukubona okungacacile
• Ukuqunjelwa
• Isicanucanu noma ukungakhululeki kwesisu
• Ubunzima bokuchama
• Ukudideka noma izinkinga zenkumbulo

Le miphumela ngokuvamile yenzeka ngoba i-biperiden ithinta ama-receptor afanayo emzimbeni wakho wonke, hhayi nje ebuchosheni bakho. Ukuhlala unamanzi, ukusebenzisa uswidi ongenashukela ngomlomo owomile, nokusukuma kancane kungasiza ekuphatheni lezi zimpawu.

Imiphumela engavamile kodwa ebucayi idinga ukunakekelwa kwezokwelapha ngokushesha:

• Ukudideka okukhulu noma ukucabanga okungelona iqiniso
• Ukushaya kwenhliziyo okusheshayo noma ukushaya kwenhliziyo okungajwayelekile
• Ubunzima obukhulu bokuchama noma ukungakwazi ukuchama
• Umkhuhlane ophezulu nokujuluka okuncishisiwe
• Ukuqunjelwa okukhulu noma ubuhlungu besisu
• Ushintsho olukhulu lwemizwa noma ukucasuka

Izinkinga ezingavamile kodwa ezinzima zingabandakanya ubuthi be-anticholinergic, obungase bubangele i-delirium, izinga lokushisa lomzimba eliphezulu kakhulu, noma i-coma. Nakuba kungavamile, lezi zimo zidinga ukunakekelwa kwezempilo eziphuthumayo.

Obani okungafanele basebenzise i-Biperiden?

Abantu abathile kufanele bagweme i-biperiden ngenxa yengozi eyengeziwe yezinkinga. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuyalela lo muthi.

Akufanele usebenzise i-biperiden uma une-narrow-angle glaucoma, njengoba ingakhuphula ingcindezi yamehlo futhi ibangele ukulahlekelwa umbono. Abantu abane-prostate enwetshiwe noma ukugcinwa komchamo kufanele futhi bayigweme, ngoba i-biperiden ingenza lezi zimo zibe zimbi kakhulu.

Uma une-myasthenia gravis, isimo esibangela ubuthakathaka bemisipha, i-biperiden ingenza izimpawu zakho zibe zimbi kakhulu. Umuthi ungalimaza futhi abantu abanezifo zenhliziyo ezinzima noma ukushaya kwenhliziyo okungajwayelekile.

Abantu abadala badinga ukucatshangelwa okukhethekile, njengoba bezwela kakhulu emiphumeleni ye-biperiden. Umuthi ungakhuphula ukudideka, ukuwa, nezinye izinkinga ezigulini ezindala, ngakho odokotela bavame ukuqala ngemithamo ephansi.

Izingane ezingaphansi kweminyaka emi-3 ubudala akufanele zithole i-biperiden, futhi izingane ezindala zidinga ukulinganiswa ngokucophelela ngokusekelwe esisindweni sazo kanye nesimo sezempilo.

Amagama e-Brand e-Biperiden

I-Biperiden itholakala ngaphansi kwamagama amaningi e-brand ngokuya ngendawo yakho. Igama elivamile le-brand yi-Akineton, etholakala kabanzi emazweni amaningi.

Amanye amagama e-brand afaka i-Biperiden Neuraxpharm kanye nezindlela ezihlukahlukene ezivamile. Ikhemisi lakho lingase lithwale amagama ahlukene e-brand, kodwa isithako esisebenzayo sihlala sifana kungakhathaliseki ukuthi ngubani umenzi.

Izinhlobo ezivamile ze-Biperiden

Izinhlobo ezivamile ze-biperiden ngokuvamile azibizi futhi zisebenza kahle njengezinhlobo ezinamagama. Udokotela wakho noma usokhemisi angakusiza ukuthi uqonde ukuthi iyiphi inketho esebenza kangcono esimweni sakho kanye nesabelomali sakho.

Ezinye izindlela ze-Biperiden

Eminye imithi eminingana ingelapha izifo ezifanayo zokunyakaza uma i-biperiden ingakulungele. Udokotela wakho angase acabangele lezi ezinye izindlela ngokusekelwe esimweni sakho esithile kanye nomlando wezokwelapha.

I-Trihexyphenidyl (Artane) ngomunye umuthi we-anticholinergic osebenza ngendlela efana ne-biperiden. Ivame ukusetshenziselwa izimo ezifanayo futhi ingase ithandwe uma uhlangabezana nemiphumela ethile emibi nge-biperiden.

I-Benztropine (Cogentin) enye indlela ejwayelekile, ethandwa kakhulu e-United States. Inemiphumela efanayo kodwa ingase ithuthukiswe kangcono ngabanye abantu noma isebenze kangcono ezinhlotsheni ezithile zezifo zokunyakaza.

Ngesifo sikaParkinson, udokotela wakho angase aphonse i-carbidopa-levodopa (Sinemet) noma ama-dopamine agonists afana ne-pramipexole. Le mithi isebenza ngendlela ehlukile kune-biperiden kodwa ingase isebenze kangcono ngezimpawu ezithile zikaParkinson.

Izindlela ezingezona zemithi ezinjengokwelashwa ngokomzimba, ukwelashwa komsebenzi, noma ukukhuthazwa kobuchopho obujulile kungase kube ezinye izinketho zezinye izifo zokunyakaza.

Ingabe i-Biperiden ingcono kune-Trihexyphenidyl?

Kokubili i-biperiden ne-trihexyphenidyl ziyimithi ye-anticholinergic esebenzayo enezinzuzo nemiphumela emibi efanayo. Ukukhetha phakathi kwazo kuvame ukuncika ekuphenduleni kwakho komuntu ngamunye kanye nokubekezelela.

I-Biperiden ingase ibangele ukuthula okuncane kwabanye abantu, okuyenza ithandeke uma ukulala kuyinkinga. Futhi ivame ukuba nesikhathi esiqinisekisayo sokusebenza, nemiphumela ehlala amahora angu-6 kuya kwangu-8 ngokuqhubekayo.

I-Trihexyphenidyl, ngakolunye uhlangothi, ingase ibe ngcono kubantu abadinga ukukhululeka okuhlala isikhathi eside, njengoba ngezinye izikhathi ingasebenza amahora angu-8 kuya kwangu-12. Abanye abantu futhi bayayithola isebenza kangcono ezinhlotsheni ezithile zokuthuthumela.

Udktela wakho uzocabangela izinto ezinjengeminye imithi oyithathayo, izimo zakho zezokwelapha, nendlela yakho yokuphila lapho ekhetha phakathi kwalezi zinketho. Ngezikhathi ezithile, ukuzama umuthi owodwa kuqala kusiza ukunquma ukuthi yimuphi osebenza kangcono esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Biperiden

Ingabe i-Biperiden iphephile ezigulini zenhliziyo?

I-Biperiden idinga ukuqapha uma unesifo senhliziyo, ikakhulukazi uma unezinhliziyo ezingahlelekile noma izimo ezinzima zenhliziyo. Umuthi ungathinta ukushaya kwenhliziyo yakho futhi ukhulise izinga lokushaya kwenhliziyo yakho.

Udktela wakho uzohlola ngokucophelela impilo yenhliziyo yakho ngaphambi kokukuyala i-biperiden. Bangase bayale i-EKG noma ezinye izivivinyo zenhliziyo ukuze baqinisekise ukuthi iphephile kuwe. Uma unezinkinga ezincane zenhliziyo, udktela wakho angase akuyalele i-biperiden kodwa akuqaphele eduze.

Njalo tshela udktela wakho nganoma yiziphi izimo zenhliziyo, ubuhlungu besifuba, noma ukushaya kwenhliziyo okungahlelekile ngaphambi kokuqala i-biperiden. Bangasiza ukunquma ukuthi izinzuzo zidlula izingozi esimweni sakho esithile.

Ngingenzani uma ngithatha i-Biperiden eningi ngengozi?

Uma uthatha i-biperiden eningi, xhumana nodktela wakho noma isikhungo sokulawula ubuthi ngokushesha. Izimpawu zokweqisa zingabandakanya ukudideka okukhulu, ukucabanga okungamanga, ukushaya kwenhliziyo okusheshayo, umkhuhlane ophezulu, nobunzima bokuphefumula.

Ungazami ukuzenza uhlanze noma uthathe eminye imithi ngaphandle kwesiqondiso sezokwelapha. Gcina ibhodlela le-biperiden unawo lapho ufuna usizo, njengoba ochwepheshe bezokwelapha bazodinga ukwazi ngqo ukuthi ungakanani okuthathile.

Ukwelashwa kwasekuqaleni kokweqisa kwe-biperiden kubalulekile ukuvimbela izinkinga ezinzima. Amagumbi eziphuthumayo anokwelashwa okuthile okutholakalayo, okuhlanganisa imithi engahlehlisa imiphumela ye-biperiden uma kudingeka.

Ngingenzani uma ngiphuthelwa umthamo we-Biperiden?

Uma uphuthelwa umthamo we-biperiden, yithathe ngokushesha nje lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Esimweni esinjalo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha ama-alamu ocingweni noma ukusebenzisa umhleli wamaphilisi ukukusiza ukhumbule.

Uma uvame ukuphuthelwa imithamo, khuluma nodokotela wakho mayelana nokulungisa ishejuli yakho noma ukuthola amasu okuthuthukisa ukuqina. Ukuphuthelwa imithamo kungavumela izimpawu zakho zokunyakaza ukuthi zibuye.

Ngingayeka nini ukuthatha i-Biperiden?

Yeka kuphela ukuthatha i-biperiden uma udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Ukuyeka kungazelelwe kungabangela izimpawu zokuhoxiswa noma kuvumele izinkinga zakho zokuqala zokunyakaza ukuthi zibuye ngokuqinile.

Udokotela wakho ngokuvamile uzokwehlisa umthamo wakho kancane kancane ezinsukwini eziningana noma emasontweni kunokuyeka kungazelelwe. Lokhu kwehliswa kancane kancane kusiza ekuvikeleni izimpawu zokuhoxiswa futhi kuvumela umzimba wakho ukuthi ulungise.

Isikhathi sokuyeka sincike ekutheni kungani uthatha i-biperiden. Uma kungokwezimpawu ezibangelwa imithi, ungase uyeke lapho uyeka imithi ebangela. Ezimweni ezingapheli, isinqumo sinzima kakhulu futhi sincike ohlelweni lwakho lokwelashwa olujwayelekile.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Biperiden?

Kungcono ukugwema utshwala ngenkathi uthatha i-biperiden, njengoba zombili lezi zinto zingabangela ukozela nokudideka. Ukuzihlanganisa kungakhuphula le miphumela ngokuphawulekayo futhi kukwenze ukuthi uthambekele ekuweni noma ekuphathweni yizingozi.

Uma ukhetha ukuphuza ngezikhathi ezithile, zilinganisele ngamanani amancane kakhulu futhi ungalokothi uphuze uma udinga ukushayela noma ukusebenzisa imishini. Inhlanganisela ingaphazamisa ukwahlulela kwakho nesikhathi sokusabela ngaphezu kwento eyodwa.

Khuluma nodokotela wakho mayelana nokusetshenziswa kotshwala ngaphambi kokuqala i-biperiden. Bangakunikeza iseluleko esiqondene nawe esisekelwe kweminye imithi yakho kanye nezimo zempilo.