C1 esterase inhibitor recombinant (indlela ye-intravenous)
Imikhiqizo etholakalayo
Ruconest
Mayelana naleli khambi
I-C1 esterase inhibitor recombinant isetshenziswa ekwelapheni i-hereditary angioedema (HAE) kubantu abadala nakwizisulu. I-HAE yisifo esingavamile esibangela ukukhuluphala kobuso, izandla, izinyawo, umlomo, isisu, amabele, noma izitho zocansi. Abantu abane-HAE banamanqanaba aphansi e-C1 esterase inhibitor emizimbeni yabo, futhi le miyekezo ikhulisa inani le-C1 esterase inhibitor emzimbeni. Lolu lwelapha luyatholakala kuphela ngomyalelo wochwepheshe wezokwelapha. Lo mkhiqizo uyatholakala ngezindlela zokulinganisela ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekucatshangeni kokusebenzisa imithi, izingozi zokuthatha imithi kumele zilinganiswe nezinzuzo ezizokwenza. Lo ngumqondo owenzayo wena nodokotela wakho. Kule mithi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqakathekile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unanoma yiluphi olunye uhlobo lwezifo ezingaleki, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenaso iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-C1 esterase inhibitor recombinant kubantwana abaneminyaka eyi-12 nangaphansi. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele azikwenzelwanga ubuhlobo bobudala nemiphumela ye-C1 esterase inhibitor recombinant kubantu abadala. Ukuphepha nokuphumelela akukaqiniswa. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Tshela ochwepheshe bakho bezempilo uma uthatha noma iyiphi enye imithi yokuqaphela noma engekho iresiphi (over-the-counter [OTC]). Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma ngesikhathi sokudla izinhlobo ezithile zokudla ngoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungabangela ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemithi yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Umshula wesibeletho noma omunye ochwepheshe bezempilo oqeqeshwe uzohlinzeka ngalolu hlobo lwemiyeke. Lolu hlobo lwemiyeke lunikezwa ngenhlanzi ebekwe kwenye yezinsimbi zakho. Imithi kufanele ihlanganiswe kancane, ngakho-ke i-IV yakho kufanele ihlale isikhathi esingamaminithi ama-5. Lolu hlobo lwemiyeke ngezinye izikhathi lunganikwa ekhaya kubantu abangadingi ukuba esibhedlela noma ekliniki. Uma usebenzisa le miyeke ekhaya, udokotela wakho noma umshula wesibeletho uzoqeqesha ukuthi ulungiselele futhi uhlanganise kanjani imithi. Qiniseka ukuthi uyayiqonda indlela yokusebenzisa imithi. Qiniseka ukuthi amalungu omndeni noma abanye abantu obaphethe bayazi ukuthi bangayifaka kanjani imithi uma ungakwazi ukuyenza wena ngesikhathi sokuhlaselwa yi-HAE. Sebenzisa inhlanzi ne-syringe entsha njalo lapho uhlanganisa imithi yakho. Hlola ama-injection kits njalo ukuqinisekisa ukuthi uthuli noma ulwetshe alushintshanga umbala. Ungasebenzisi le miyeke uma uthuli noma ulwetshe lushintshe umbala, noma uma kukhona izinto eziqinile ekuhlanganiseni okulwetshe. Thatha le miyeke nawe njalo ukuze uyisebenzise ngesikhathi esiphuthumayo uma uhlushwa yi-HAE. Lolu hlobo lwemiyeke luza nephepha lemininingwane yomguli. Funda futhi ulandele imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Inani lemiyeke lizobahlukile kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale miyeke. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuyale ukuba wenze njalo. Inani lemiyeke oyithatha lixhomeke emandleni emiyeke. Futhi, inani lemithi oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwemithi, nobude besikhathi othatha imithi kuya ngenkinga yezokwelapha oyisebenzisela imithi. Shaya udokotela wakho noma i-pharmacist ukuze uthole imiyalo. Gcina ungafinyeleleki ezinganeni. Ungagcini imithi eliphelile noma imithi engasadingeki. Buza ochwepheshe bezempilo ukuthi kufanele uyilahla kanjani imithi oyisebenzisanga. Gcina ibhodlela lothuli esihlalweni esibandayo noma ekamelweni lokushisa. Gcina imithi ebhokisini lokuqala kuze kube yilapho usulungele ukuyisebenzisa. Ungayiganduki. Sebenzisa imithi ehlanganisiwe ngokushesha, noma ungayigcina esihlalweni esibandayo phakathi namahora angu-8 emva kokuyihlahlanya. Lahla ibhodlela ngemva kokuyisebenzisa, ngisho noma kukhona imithi esele kulo.