Iyini i-Cabergoline: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Cabergoline iyimithi kadokotela esiza ukulawula amazinga aphezulu e-hormone ebizwa ngokuthi i-prolactin emzimbeni wakho. Udokotela wakho angase akunikeze lo muthi uma unezimo ezinjenge-prolactinomas (izimila ezingenasici ezikhiqiza i-prolactin eningi kakhulu) noma ezinye izifo lapho amazinga akho e-prolactin ephakeme kunalokho okufanele abe yikho.

Lo muthi usebenza ngokulingisa ikhemikhali yobuchopho yemvelo ebizwa ngokuthi i-dopamine, esiza ukulawula ukukhiqizwa kwe-hormone. Cabanga ngayo njengebhegi elithambile elinciphisa ukukhiqizwa kwe-prolactin emzimbeni wakho ukuze ilibuyisele emazingeni anempilo.

Iyini i-Cabergoline?

I-Cabergoline ingeyeqembu lemithi ebizwa ngokuthi ama-dopamine agonists. Kuyinguqulo yokwenziwa yekhemikhali ubuchopho bakho obukhiqiza ngokwemvelo ukusiza ukulawula amazinga ahlukahlukene e-hormone emzimbeni wakho wonke.

Umuthi uza ngamaphilisi amancane owathatha ngomlomo, ngokuvamile kanye noma kabili ngesonto. Ngokungafani nemithi yansuku zonke, i-cabergoline inemiphumela ehlala isikhathi eside ohlelweni lwakho, yingakho ungadingi ukuyithatha nsuku zonke.

Udokotela wakho uzokunikeza i-cabergoline lapho umzimba wakho ukhiqiza i-prolactin eningi kakhulu, i-hormone evame ukusiza ekukhiqizweni kobisi komama abancelisayo. Lapho amazinga e-prolactin eba phezulu kakhulu kubantu abangancelisi, kungabangela izimpawu ezihlukahlukene ezingakhululeki.

Isetshenziselwani i-Cabergoline?

I-Cabergoline ngokuyinhloko iphatha izifo ezibangelwa i-prolactin eningi kakhulu egazini lakho, isimo esibizwa ngokuthi i-hyperprolactinemia. Lokhu kwenzeka lapho i-pituitary gland yakho ikhiqiza i-prolactin eningi kunezidingo zomzimba wakho.

Isizathu esivame kakhulu sokuthi odokotela banikeze i-cabergoline yi-prolactinomas, okuyizimila ezingenasici e-pituitary gland yakho. Lokhu kukhula okuncane kungabangela amazinga akho e-prolactin ukuthi anyuke kakhulu, okuholela ezimpawini ezihlukahlukene ezithinta impilo yakho yansuku zonke.

Nawa amakhondishini amakhulu i-cabergoline esiza ukuwelapha, siqala ngezizathu ezivame kakhulu udokotela wakho angasezincoma:

• Ama-Prolactinomas (izimila ze-pituitary ezingenasici)
• Amazinga aphezulu e-prolactin angachazeki
• Izikhathi ezingajwayelekile noma ezingekho zokuya esikhathini ezibangelwa i-prolactin ephezulu
• Ukukhiqizwa kobisi olungafuneki ebeleni kwabesifazane abangancelisi
• Izinkinga zokuzala ezihlobene ne-prolactin ephezulu
• Ukungasebenzi kahle ngokocansi okubangelwa amazinga e-prolactin aphakeme

Kwezinye izimo, odokotela bangase banikeze i-cabergoline ngesifo i-Parkinson, nakuba lokhu kungavamile. Umhlinzeki wakho wokunakekelwa kwezempilo uzonquma ukuthi i-cabergoline ilungele yini isimo sakho esithile.

Isebenza Kanjani I-Cabergoline?

I-Cabergoline isebenza ngokubopha kuma-receptors e-dopamine ebuchosheni bakho, ikakhulukazi ku-pituitary gland lapho i-prolactin yenziwa khona. Lapho umuthi unamathisela kula ma-receptors, uthumela isignali yokunciphisa ukukhiqizwa kwe-prolactin.

Lo muthi uthathwa njengomuthi onamandla ngokulinganisela futhi osebenza kahle kakhulu ngenjongo yawo. Abantu abaningi babona ukuthuthuka okukhulu emazingeni abo e-prolactin kungakapheli amasonto ambalwa beqala ukwelashwa.

Umuthi uhlala usebenza emzimbeni wakho izinsuku eziningana, yingakho ngokuvamile udinga ukuwuthatha kanye noma kabili ngesonto. Lo mphumela ohlala isikhathi eside wenza kube lula kunemithi edinga ukulinganiswa kwansuku zonke.

Kufanele Ngiyithathe Kanjani I-Cabergoline?

Thatha i-cabergoline ngendlela udokotela wakho ayincomayo, ngokuvamile kanye noma kabili ngesonto ngokudla. Ukuyithatha nokudla noma ukudla okulula kusiza ukunciphisa ukuquleka kwesisu futhi kuthuthukisa ukuthi umzimba wakho umunca kahle kangakanani umuthi.

Ungathatha i-cabergoline ngamanzi, ubisi, noma ijusi. Ukuba nokudla esiswini sakho ngaphambi kokuthatha iphilisi kusiza ukuvimbela isicanucanu, esinye sezifo ezivamile lapho uqala lo muthi.

Nakhu okufanele ukwazi mayelana nokuthatha i-cabergoline ngokuphepha:

• Yithatha ngosuku olufanayo njalo ngesonto ukuze ugcine amazinga aqhubekayo
• Yidla ukudla okulula noma ukudla okulula imizuzu engama-30 ngaphambi kokuthatha iphilisi
• Gwema utshwala ezinsukwini ozothatha ngazo i-cabergoline
• Ungachobozi noma uhlafune amaphilisi
• Gcina imithi endaweni epholile, eyomile

Uma uzizwa unesiyezi noma unomuzwa wokukhathala ngemva kokuthatha i-cabergoline, lalela phansi isikhashana futhi gwema ukushayela noma ukusebenzisa imishini. Le miphumela ivamise ukuthuthuka njengoba umzimba wakho ujwayela imithi.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Cabergoline?

Abantu abaningi badinga ukuthatha i-cabergoline izinyanga eziningana kuya eminyakeni, kuye ngesimo sabo esithile. Udokotela wakho uzoqapha amazinga akho e-prolactin njalo ukuze anqume ukuthi udinga ukwelashwa isikhathi esingakanani.

Nge-prolactinomas, ungase udinge ukuthatha i-cabergoline iminyaka engu-2-3 noma ngaphezulu. Abanye abantu abanezicubu ezincane bangagcina beyeka imithi uma amazinga abo e-prolactin ejwayelekile futhi ezinzile.

Umhlinzeki wakho wezempilo uzoqoka izivivinyo zegazi ezivamile ukuze ahlolisise amazinga akho e-prolactin futhi angase futhi ayale izivivinyo zenhliziyo ngezikhathi ezithile. Ungayeki ukuthatha i-cabergoline ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala, ngoba lokhu kungabangela amazinga akho e-prolactin ukuthi anyuke ngokushesha futhi.

Yiziphi Imiphumela Eceleni Ye-Cabergoline?

Abantu abaningi bayayibekezelela i-cabergoline kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi. Izindaba ezinhle ukuthi imiphumela eminingi emibi imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela imithi.

Imiphumela emibi ejwayelekile ethinta abantu abaningi ihlanganisa isicanucanu, isiyezi, nekhanda. Lokhu kuvame ukwenzeka emasontweni ambalwa okuqala okwelashwa futhi kuvame ukuba ngaphansi kokuphazamisa ngokuhamba kwesikhathi.

Nansi imiphumela emibi ebikwa kaningi, ehlelwe kusukela kokujwayelekile kuya kokungajwayelekile:

• Isicanucanu nokucasuka kwesisu
• Isiyezi noma ukukhathala
• Ikhanda
• Ukukhathala noma ukukhathala
• Ukuqunjelwa
• Umlomo owomile
• Izinkinga zokulala noma amaphupho acacile

Imiphumela engavamile kodwa ebucayi ingenzeka, nakuba ithinta abantu abambalwa. Lokhu kudinga ukunakekelwa kwezokwelapha ngokushesha uma kwenzeka kuwe:

• Ubuhlungu besifuba noma ukushaya kwenhliziyo okusheshayo
• Ukuphefumula kanzima
• Ukuvuvukala emilenzeni noma ezinyaweni
• Ukuqala okungazelelwe kokugembula noma izifiso zocansi
• Ukucabanga okungahambi kahle noma ukudideka
• Ubuhlungu obukhulu besisu

Imiphumela engavamile kodwa ebucayi ihlanganisa izinkinga zamavalvu enhliziyo, yingakho udokotela wakho engase ayalele ukuhlolwa kwenhliziyo ngezikhathi ezithile. Uma uba nanoma yiziphi izimpawu ezingavamile, xhumana nomhlinzeki wakho wezempilo ngokushesha.

Ubani Ongafanele Athathe I-Cabergoline?

I-Cabergoline ayiphephile kuwo wonke umuntu, futhi izimo ezithile zezempilo ziyenza ingafaneleki. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokukuchazela lo muthi.

Abantu abanomfutho wegazi ophezulu ongagadiwe akufanele bathathe i-cabergoline, njengoba ingase iqhubekisele phambili lesi simo. Umuthi ungenza futhi ukuthi usebenzisane ngendlela eyingozi nemithi ethile yenhliziyo nemithi yomfutho wegazi.

Nazi izimo eziyinhloko nezimo lapho i-cabergoline kufanele igwenywe khona:

• Ukungezwani okwaziwayo ne-cabergoline noma imithi efanayo
• Umfutho wegazi ophezulu ongagadiwe
• Isifo samavalvu enhliziyo noma umlando wezinkinga zenhliziyo
• Isifo sesibindi esibi kakhulu
• Ukukhulelwa (ngaphandle uma kuchazwe ngokuqondile ngudokotela wakho)
• Omama abancelisa izingane abazama ukucindezela ukukhiqizwa kobisi

Imithi ethile ingase isebenzisane ne-cabergoline, okuhlanganisa eminye imithi ye-antipsychotic, imithi yomfutho wegazi, kanye nemithi elwa nesicanucanu. Hlala utshela udokotela wakho ngayo yonke imithi, izithasiselo, kanye nemithi yezitshalo oyithathayo.

Amagama Omkhiqizo we-Cabergoline

I-Cabergoline itholakala ngaphansi kwamagama amaningi omkhiqizo, i-Dostinex iyona eqashelwa kakhulu. Ikhemisi lakho lingase linikeze umuthi ngaphansi kwamagama ahlukene kuye ngomkhiqizi.

Amanye amagama emikhiqizo ahlanganisa i-Cabaser ne-Cabaseril, nakuba ukutholakala kuhluka ngokuya ngezwe. Uhlobo olujwayelekile olubizwa ngokuthi "cabergoline" luyatholakala kabanzi futhi lusebenza ngempumelelo njengoba kwenza izinhlobo ezinamagama emikhiqizo.

Noma ngabe yiluphi uhlobo olulitholayo, isithako esisebenzayo nokusebenza kahle kuhlala kufana. Umkhemisi wakho angaphendula noma yimiphi imibuzo mayelana nohlobo oluthile abalunikezayo kuwe.

Ezinye Izindlela Zokwelapha Nge-Cabergoline

Eminye imithi eminingi ingelapha amazinga aphezulu e-prolactin uma i-cabergoline ingakulungele. I-Bromocriptine iyindlela ejwayelekile futhi isebenza ngendlela efana ne-cabergoline.

I-Bromocriptine idinga ukulinganiswa kwansuku zonke futhi ingase ibangele imiphumela eminingi kuno-cabergoline, kodwa ivame ukuba ngentengo ephansi futhi isetshenziswe ngokuphepha iminyaka eminingi. Abanye abantu bayamukela i-bromocriptine kangcono kune-cabergoline.

Ezinye izindlela ezingase zicatshangelwe udokotela wakho zihlanganisa:

• I-Bromocriptine (Parlodel) - ithathwa nsuku zonke
• I-Quinagolide - ithathwa nsuku zonke
• Ukuhlinzwa kwama-prolactinomas amakhulu
• Ukwelashwa ngemisebe ezimweni ezingavamile

Udokotela wakho uzokusiza ukhethe inketho yokwelashwa engcono kakhulu ngokusekelwe esimweni sakho esithile, ezinye izinkinga zempilo, nokuthi uzamukela kanjani imithi ehlukene.

Ingabe i-Cabergoline Ingcono Kune-Bromocriptine?

I-Cabergoline ngokuvamile ithathwa njengempumelelo enkulu futhi yamukeleka kangcono kune-bromocriptine ekwelapheni amazinga aphezulu e-prolactin. Abantu abaningi bakhetha i-cabergoline ngoba ithathwa kaningi futhi ibangela imiphumela emincane.

Ucwaningo lubonisa ukuthi i-cabergoline isebenza kahle ekujwayeleni amazinga e-prolactin nokunciphisa ama-prolactinomas. Cishe ama-85-90% abantu bafinyelela amazinga e-prolactin ajwayelekile nge-cabergoline, uma kuqhathaniswa nama-70-75% nge-bromocriptine.

Izinzuzo eziyinhloko ze-cabergoline ngaphezu kwe-bromocriptine zihlanganisa ukulinganiswa okungavamile (kabili ngesonto vs. nsuku zonke), imiphumela emibi emincane emathunjini, nemiphumela engcono yesikhathi eside. Kodwa-ke, i-cabergoline ivame ukubiza kakhulu kune-bromocriptine.

Udokotela wakho uzocabangela izinto ezinjengamazinga akho e-prolactin, usayizi womdlavuza, ukubekezelelana nemiphumela emibi, kanye nezindleko lapho ekhetha phakathi kwale mithi. Abanye abantu benza ngcono nge-bromocriptine naphezu kwezinzuzo ezijwayelekile ze-cabergoline.

Imibuzo Evame Ukubuzwa Nge-Cabergoline

Q1. Ingabe i-Cabergoline Iphephile Ezigulini Zezinhliziyo?

I-Cabergoline idinga ukuqapha ngokucophelela kubantu abanezifo zenhliziyo. Udokotela wakho cishe uzo-oda i-echocardiogram ngaphambi kokuqala ukwelashwa futhi ngezikhathi ezithile ngesikhathi sokwelashwa ukuze ahlolisise amavalvu enhliziyo yakho.

Abantu abanezinkinga ezikhona zamavalvu enhliziyo ngokuvamile kufanele bagweme i-cabergoline, njengoba ingenza lezi zimo zibe zimbi. Kodwa-ke, kubantu abanomsebenzi wenhliziyo ojwayelekile, i-cabergoline ivame ukuphepha uma isetshenziswa ngaphansi kokuqashwa kwezokwelapha.

Uma unesifo senhliziyo, qiniseka ukuthi udokotela wakho uyakwazi ngakho ngaphambi kokuqala i-cabergoline. Bangase bakhethe umuthi ohlukile noma bakuqaphe eduze ngesikhathi sokwelashwa.

Q2. Kufanele Ngenzeni Uma Ngisebenzisa I-Cabergoline Eningi Ngengozi?

Ukuthatha i-cabergoline eningi kungabangela isicanucanu esibi, ukuhlanza, isiyezi, kanye nomfutho wegazi ophansi kakhulu. Uma ngengozi uthatha okuningi kunokunqunyiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha.

Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo uchwepheshe wezempilo. Lala endaweni ephephile futhi ube nomuntu ozohlala nawe kuze kube yilapho ungathola usizo lwezokwelapha.

Izimpawu ze-cabergoline overdose zingahlanganisa ukucabanga okungamanga, ukudideka, nokuquleka. Le miphumela ingaba yingozi, ngakho funa ukunakekelwa kwezimo eziphuthumayo uma uhlangabezana nanoma yiziphi lezi zimpawu ngemva kokuthatha umuthi omningi.

Q3. Kufanele Ngenzeni Uma Ngiphuthelwa Umthamo We-Cabergoline?

Uma uphuthelwa umthamo we-cabergoline, yithathe ngokushesha lapho ukhumbula, kodwa kuphela uma kungaphakathi kwezinsuku eziyi-1-2 zomthamo wakho ohleliwe. Ungathathi imithamo emibili ngasikhathi sinye ukuze ulungise umthamo ophuthelwe.

Uma sekudlule izinsuku ezingaphezu kweziyi-2-3 kusukela kumthamo wakho ophuthelwe, weqe bese uthatha umthamo wakho olandelayo njengoba kuhleliwe. Ukuthatha i-cabergoline sekwephuzile kungcono kunokuphinda imithamo, okungabangela imiphumela emibi.

Cabangela ukusetha isikhumbuzi samaviki onyakeni wakho noma ekhalendeni ukukusiza ukuthi ukhumbule ukuthi uzothatha nini imithi yakho. Ukuqina kusiza ukugcina ukulawulwa kwe-prolactin okuqhubekayo.

Q4. Ngingayeka nini ukuthatha i-Cabergoline?

Ngokuvamile ungaqeda ukuthatha i-cabergoline lapho amazinga akho e-prolactin ebe ejwayelekile okungenani izinyanga eziyi-6-12 futhi noma iyiphi imithombo isinciphe kakhulu. Udokotela wakho uzokwenza lesi sinqumo ngokusekelwe ekuhlolweni kwegazi lakho nasezifundweni zokucabanga.

Ungayeki i-cabergoline ngokuzumayo ngaphandle kokuqondiswa kwezokwelapha, njengoba amazinga akho e-prolactin engase akhuphuke ngokushesha futhi. Udokotela wakho ngokuvamile uzonciphisa umthamo wakho kancane kancane emasontweni amaningana ngaphambi kokuyeka ngokuphelele.

Abanye abantu badinga ukuthatha i-cabergoline isikhathi eside, ikakhulukazi uma benama-prolactinomas amakhulu noma uma amazinga abo e-prolactin ekhuphuka futhi ngemva kokuyeka. Ukuqokwa okuvamile kokulandela ngemuva kusiza ukunquma indlela engcono kakhulu yesimo sakho.

Q5. Ngingayithatha i-Cabergoline ngesikhathi ngikhulelwe?

I-Cabergoline ngokuvamile ayinconywa ngesikhathi sokukhulelwa ngaphandle uma udokotela wakho eyibeka ngokuqondile isimo esibi. Umuthi ungawela i-placenta futhi ungase uthinte ingane yakho ekhulayo.

Uma uzama ukukhulelwa, khuluma nodokotela wakho mayelana nokuthi uzoqhubeka yini nokuthatha i-cabergoline. Abanye besifazane abane-prolactinomas badinga ukuhlala emithini ngesikhathi sokukhulelwa ukuze bavimbele ukukhula kwemithombo.

Njalo sebenzisa izindlela zokuvimbela inzalo ezisebenzayo ngenkathi uthatha i-cabergoline ngaphandle uma ngamabomu uzama ukukhulelwa ngaphansi kokuqondisa kwezokwelapha. Uma ukhulelwa ngenkathi uthatha i-cabergoline, xhumana nodokotela wakho ngokushesha ukuze nixoxe ngezindlela ezingcono kakhulu zokwenza.