Yini iCabotegravir: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

ICabotegravir ngumuthi we-HIV osebenza isikhathi eside oza ngomjovo owuthola kanye njalo ezinyangeni ezimbili. Ingaphansi kohlobo lwemithi ebizwa ngokuthi ama-integrase inhibitors, asebenza ngokuvimbela i-HIV ukuthi ingazikopishi ngaphakathi kwamaseli akho. Lo muthi umelela isinyathelo esikhulu phambili ekwelashweni kwe-HIV, unikeza abantu abaphila ne-HIV enye indlela yamaphilisi ansuku zonke.

Umjovo we-intramuscular unikezwa ujule emsipheni wakho, ngokuvamile ezinqeni zakho, ngumhlinzeki wokunakekelwa kwezempilo endaweni yezokwelapha. Uzodinga ukuvakashela ihhovisi likadokotela wakho noma umtholampilo njalo ngamaviki ayisishiyagalombili ukuze uthole umjovo wakho, okwenza kube yindlela elula kubantu abangathandi ukuthatha imithi yansuku zonke.

Yini iCabotegravir Esetshenziselwa Yona?

Umjovo weCabotegravir usetshenziselwa ukwelapha ukutheleleka nge-HIV kubantu abadala nasebancane abalinganisa okungenani amakhilogremu angama-35 (cishe amaphawundi angama-77). Yenzelwe abantu i-HIV yabo esilawulwa kahle ngeminye imithi futhi abafuna ukushintshela ekwelashweni okusebenza isikhathi eside.

Awukwazi ukuqala imijovo ye-cabotegravir ngokushesha uma usanda kutholwa ukuthi une-HIV. Udokotela wakho uzokuqala aqinisekise ukuthi umthwalo wakho we-HIV awutholakali esebenzisa eminye imithi ye-HIV, ngokuvamile okungenani izinyanga ezintathu. Lokhu kuqinisekisa ukuthi i-cabotegravir izosebenza kuwe.

Umjovo unikezwa ngaso sonke isikhathi kanye ne-rilpivirine, omunye umuthi we-HIV osebenza isikhathi eside. Lokhu kwelashwa okuhlanganisiwe kusiza ekuvikeleni i-HIV ekuthuthukiseni ukumelana nanoma yimuphi umuthi, kugcina ukwelashwa kwakho kusebenza ngokuhamba kwesikhathi.

Isebenza Kanjani iCabotegravir?

ICabotegravir isebenza ngokuvimba i-enzyme ebizwa ngokuthi i-integrase edingwa yi-HIV ukuze izizale ngaphakathi kwamaseli akho. Cabanga nge-integrase njengokhiye i-HIV ewusebenzisela ukufaka impahla yayo yofuzo emaseleni akho anempilo. Ngokuvimba lo khiye, i-cabotegravir ivimbela i-HIV ekuzikopishini.

Lo muthi ubhekwa njengomuthi onamandla futhi osebenzayo we-HIV. Uma ihlanganiswe ne-rilpivirine, idala isithiyo esiqinile sokulwa nokuzala kabusha kwe-HIV. Ifomula esebenza isikhathi eside isho ukuthi umuthi uhlala emzimbeni wakho amasonto, unikeza ukuvikelwa okuqhubekayo ku-HIV.

Ngenxa yokuthi i-cabotegravir ikhishwa kancane endaweni yokujova, igcina amazinga okuphulukisa egazini lakho cishe izinyanga ezimbili. Lokhu kukhishwa okuqhubekayo yikho okwenza ukuthi kube nokwenzeka ukuhlela umthamo njalo ngamaviki ayisishiyagalombili.

Kufanele Ngiyithathe Kanjani I-Cabotegravir?

I-Cabotegravir inikezwa njengomjovo we-intramuscular ngumhlinzeki wakho wezempilo, ngakho akudingeki ukhathazeke ngokuyithatha wena. Umjovo unikezwa ujule emsipheni wezinqulu zakho, ushintshana phakathi kohlangothi lwesobunxele nesokudla ngokuqokwa ngakunye.

Ngaphambi kokuqala imijovo esebenza isikhathi eside, udokotela wakho cishe uzokwenza ukuthi uthathe amaphilisi e-cabotegravir ne-rilpivirine ngomlomo cishe inyanga. Lesi sikhathi sokuqala ngomlomo sisiza ukuqinisekisa ukuthi uyawamukela kahle imithi ngaphambi kokuzibophezela ohlotsheni olujovwayo.

Akudingeki ukuthi uzile noma udle ukudla okuthile ngaphambi kokuthola umjovo wakho. Kodwa-ke, kufanele ufike ekuqokweni kwakho uhlanzekile futhi ukhululekile. Umjovo ngokwawo uthatha imizuzu embalwa nje, yize kungase kudingeke ulinde emtholampilo isikhathi esifushane sokubheka ngemva kwalokho.

Umhlinzeki wakho wezempilo uzohlela imijovo yakho njalo ngamaviki ayisishiyagalombili, futhi kubalulekile ukugcina la ma-aphoyintimenti. Ukulahlekelwa noma ukuhlehlisa imijovo kungaholela ekwehleni kwamazinga emithi kanye nokwehluleka kokwelashwa okungenzeka.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Cabotegravir?

I-Cabotegravir ukwelashwa kwesikhathi eside kwe-HIV, okusho ukuthi cishe uzoqhubeka nokuthola imijovo iminyaka noma okungenzeka impilo yakho yonke. Ukwelashwa kwe-HIV kuvame ukuba yimpilo yonke ngoba ukuyeka imithi ephumelelayo ye-HIV kuvumela igciwane ukuthi liphindaphindeke futhi, ngisho noma ngabe ngaphambili lingatholakali.

Udkt. wakho uzoqapha intuthuko yakho ngezivivinyo zegazi ezivamile ukuze ahlolisise izinga lakho le-viral load kanye nenani le-CD4 cell. Uma nje imithi iqhubeka nokugcina i-HIV yakho icindezelwe futhi uyayithola kahle, uzoqhubeka neshejuli yokujova yamasonto ayisishiyagalombili.

Uma udinga ukuyeka imijovo ye-cabotegravir nganoma yisiphi isizathu, udkt. wakho ngeke amane ayiyeke ngokuphazima kweso. Kunalokho, bazokushintshela emithini yomlomo ye-HIV yansuku zonke ukuze baqinisekise ukwelashwa okuqhubekayo futhi bavimbele i-HIV yakho ekubeni imelane nemithi.

Yini Imiphumela Eceleni ye-Cabotegravir?

Njengayo yonke imithi, i-cabotegravir ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Imiphumela emibi evame kakhulu ngokuvamile imnene futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela imithi.

Nansi imiphumela emibi ebikwa kaningi ongase uyithole:

• Ukuphendula endaweni yokujova njengobuhlungu, ukuvuvukala, noma ububomvu
• Ukucabanga
• Umkhuhlane
• Ukukhathala noma ukudinwa
• Ukuqaqamba kwemisipha
• Isicanucanu
• Izinkinga zokulala noma amaphupho angavamile
• Isiyezi

Ukusabela endaweni yokujova ngokuvamile yimiphumela emibi ebonakala kakhulu. Ungase uzwe ubuhlungu, ubone ukuvuvukala okuthile, noma uqaphele iqhubu elincane endaweni yokujova. Lokhu kusabela ngokuvamile kulungiswa ezinsukwini ezimbalwa futhi kuvame ukuba ngaphansi kokuphazamisa ngemijovo elandelayo.

Ngenkathi kungavamile, abanye abantu bangase bathole imiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha:

• Ukusabela okukhulu komzimba okubangela ubunzima bokuphefumula noma ukuvuvukala kobuso nomphimbo
• Ukucindezeleka okukhulu noma imicabango yokuzilimaza
• Izinkinga zesibindi eziboniswa ukuphuzi kwesikhumba noma amehlo
• Ukusabela okuqhubekayo okukhulu endaweni yokujova okungathuthuki
• Izimpawu zokushintsha kwamasosha omzimba njengokutheleleka okungavamile

Uma uhlangabezana nanoma yimaphi alawa maphuzu abucayi, xhumana nodokotela wakho ngokushesha noma funa ukwelashwa okuphuthumayo. Ukuphepha kwakho yikho konke okubalulekile, futhi ithimba lakho lezokwelapha lilapho ukusiza ukuphatha noma yiziphi izinkinga.

Ubani Ongafanele Athathe i-Cabotegravir?

I-Cabotegravir ayifanele wonke umuntu, futhi udokotela wakho uzohlola ngokucophelela ukuthi ilungele yini wena. Abantu abanezimo ezithile zezokwelapha noma abathatha imithi ethile kungenzeka bangabi ngabantu abafanelekayo kulokhu kwelashwa.

Akufanele uthole imijovo ye-cabotegravir uma unezinye zalezi zimo:

• Ukuphendula komzimba okwaziwayo ku-cabotegravir noma i-rilpivirine
• Ukutheleleka nge-hepatitis B okusebenzayo (kudinga ukuqapha okukhethekile)
• Isifo sesibindi esibi noma ukwehluleka kwesibindi
• Ukusetshenziswa kwamanje kwemithi ethile exhumana ngobungozi ne-cabotegravir
• I-HIV engamelani nezithiyo ze-integrase

Udokotela wakho uzosebenzisa ukuqapha uma unomlando wokucindezeleka, izimo zempilo yengqondo, noma izinkinga zesibindi. Lezi zimo akudingeki zikuvimbele ekusebenziseni i-cabotegravir, kodwa zidinga ukuqapha okuseduze futhi zingathinta uhlelo lwakho lokwelashwa.

Abesifazane abakhulelwe badinga ukucatshangelwa okukhethekile, njengoba ukuphepha kwe-cabotegravir ngesikhathi sokukhulelwa kusafundwa. Uma ukhulelwe noma uhlela ukukhulelwa, xoxa ngazo zonke izinketho zakho nodokotela wakho.

Amagama Omkhiqizo we-Cabotegravir

Umjovo we-Cabotegravir uyatholakala ngaphansi kwegama lomkhiqizo elithi Apretude uma lisetshenziswa lodwa ukuvimbela i-HIV, futhi njengengxenye ye-Cabenuva uma ihlanganiswe ne-rilpivirine yokwelashwa kwe-HIV. Igama lomkhiqizo elithile lingahluka ngokuya ngezwe lakho kanye nohlelo lwezempilo.

I-pharmacy yakho noma umhlinzeki wezempilo uzoqinisekisa ukuthi uthola ukwakheka okulungile kwezidingo zakho zokwelashwa ezithile. Zombili izindlela ziqukethe isithako esisebenzayo esifanayo, i-cabotegravir, kodwa zikhonjiswe ukusetshenziswa okuhlukile.

Ezinye izindlela ze-Cabotegravir

Uma imijovo ye-cabotegravir ingakulungele, ezinye izindlela zokwelapha i-HIV eziphumelelayo ziyatholakala. Udokotela wakho angakusiza ukuthi uthole enye indlela evumelana nendlela yakho yokuphila nezidingo zakho zezokwelapha.

Ezinye izindlela zokwelapha i-HIV ezisebenza isikhathi eside zihlanganisa imithi ehlukene ejovwayo noma amadivaysi afakelwayo, nakuba lokhu kungase kungatholakali kabanzi okwamanje. Abantu abaningi banemiphumela emihle ngemithi yomlomo ye-HIV yansuku zonke, eza ngezinhlanganisela ezihlukahlukene.

Ezinye izindlela ezithandwayo zokwelapha i-HIV ngomlomo zihlanganisa imithi yethebhulethi eyodwa ehlanganisa imithi eminingi ye-HIV ibe iphilisi elilodwa lansuku zonke. Lokhu kungase kuhlanganise izinhlanganisela zemithi efana ne-efavirenz, i-emtricitabine, ne-tenofovir, noma izinhlanganisela ezintsha ezinemithi efana ne-bictegravir.

Ukukhetha kwakho ukwelashwa kwe-HIV kufanele kucabangele izinto ezifana nendlela yakho yokuphila, ezinye izimo zezokwelapha, ukusebenzisana okungenzeka kwemithi, nezintandokazi zomuntu siqu. Okubaluleke kakhulu ukuthola ukwelashwa ongakwazi ukunamathela kukho isikhathi eside.

Ingabe i-Cabotegravir Ingcono Kunezinye Imithi Ye-HIV?

Imijovo ye-Cabotegravir akudingeki ukuthi

Udktela wakho uzokusiza ukuthi uhlole izinzuzo kanye nobubi ngokusekelwe esimweni sakho esithile, umlando wakho wezokwelapha, kanye nemigomo yokwelashwa. Umuthi ongcono kakhulu we-HIV yilowo ongawuthatha njalo futhi olawula kahle i-HIV yakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Cabotegravir

Ingabe i-Cabotegravir iphephile kubantu abane-Hepatitis B?

I-Cabotegravir idinga ukuqapha okukhethekile kubantu abane-hepatitis B co-infection. Uma une-HIV ne-hepatitis B, udktela wakho uzodinga ukuqapha ukusebenza kwesibindi sakho ngokucophelela futhi angase adinge ukwengeza imithi eyenzelwe ngqo ukwelashwa kwe-hepatitis B.

Ukukhathazeka ukuthi eminye imithi ye-HIV ingase ithinte i-hepatitis B, futhi ukuyeka ukwelashwa kwe-HIV kungazelelwe kungase kubangele i-hepatitis B ukuthi ivuthe. Ithimba lakho lokunakekelwa kwezempilo lizokwenza uhlelo olubanzi lokwelashwa olubhekana ngqo nokutheleleka kokubili ngokuphepha.

Ngingenzani uma ngiphuthelwa ngengozi ukujova kwami ​​kwe-Cabotegravir?

Uma uphuthelwa ukuqokwa kwakho kokujova okuhleliwe, xhumana nomhlinzeki wakho wezempilo ngokushesha. Isikhathi sokujova kwakho okulandelayo sincike ekutheni sekunesikhathi esingakanani kusukela emthini wakho wokugcina kanye nezimo zakho.

Udktela wakho angase ancome ukuqala imithi ye-HIV yomlomo okwesikhashana ukuze ugcine ukwelashwa kwakho ngenkathi ubuyela ohlelweni ngokujova. Ungalindi – amazinga e-HIV angakhuphuka ngokushesha ngaphandle kokwelashwa okuqhubekayo, ngakho-ke isenzo esisheshayo sibalulekile.

Ngingenzani uma ngiba nokusabela okukhulu ku-Cabotegravir?

Uma uhlangabezana nezimpawu zokusabela okukhulu komzimba njengobunzima bokuphefumula, ukuvuvukala kobuso bakho noma umphimbo, noma ukusabela okukhulu kwesikhumba, funa ukunakekelwa kwezempilo eziphuthumayo ngokushesha. Lokhu kusabela akuvamile kodwa kudinga ukwelashwa okusheshayo.

Ngezimpawu ezingezona ezinzima kodwa ezikhathazayo njengokusabela okuqhubekayo okukhulu kwendawo yokujova, izinguquko ezinzima zemizwa, noma izimpawu zezinkinga zesibindi, xhumana nomhlinzeki wakho wezempilo ngokushesha okukhulu. Bangahlola izimpawu zakho futhi balungise ukwelashwa kwakho uma kudingeka.

Ngingayeka nini ukuthatha i-Cabotegravir?

Akufanele uyeke ukujova i-cabotegravir ngaphandle kokuxoxa nodokotela wakho kuqala. Ukwelashwa nge-HIV kuvamile ukuba kube ngokuphila konke, futhi ukuyeka ukwelashwa okuphumelelayo kuvumela i-HIV ukuthi iphindaphinde, okungenzeka kuholele ekumelaneni nemithi.

Uma udinga ukuyeka i-cabotegravir ngenxa yezizathu zezokwelapha noma ukuzikhethela komuntu siqu, udokotela wakho uzokusiza ukuthi ushintshele kwenye indlela yokwelapha i-HIV ephumelelayo. Lokhu kuqinisekisa ukuthi ugcina ukucindezelwa kwe-viral okuqhubekayo futhi uvikele impilo yakho.

Ngingahamba yini ngenkathi ngithatha imijovo ye-Cabotegravir?

Yebo, ungahamba ngenkathi uthola imijovo ye-cabotegravir, kodwa uzodinga ukuhlela uhambo lwakho ngokuya ngeshejuli yakho yokujova. Njengoba udinga imijovo njalo ngamaviki ayisishiyagalombili, uzofuna ukuxhumana nodokotela wakho ngesikhathi.

Ukuze uhambe isikhathi eside, udokotela wakho angase akwazi ukukuxhumanisa nabahlinzeki bezempilo lapho uya khona abangakwazi ukukujova. Noma, bangase bakunikeze imithi yomlomo ongayisebenzisa okwesikhashana ngenkathi uhamba.