Cabozantinib (indlela yokumathisa ngomlomo)
Imikhiqizo etholakalayo
Cabometyx, Cometriq
Mayelana naleli khambi
I-Cabozantinibcapsuleisetshenziswa ekwelapheni lomdlavuza we-thyroid medullary osekuye wasakazeka ezingxenyeni ezahlukene zomzimba. I-Cabozantinibtablet isetyenziswa yodwa ekwelapheni lomdlavuza wezinso ophambili. Isetshenziswa futhi ngokuhlanganyela ne-nivolumab njengonyango lokuqala lomdlavuza wezinso ophambili. I-Cabozantinibtablet isetyenziswa futhi ekwelapheni uhlobo lomdlavuza welaphe, oluthiwa yi-hepatocellular carcinoma, kubantu abake baphathwa ngeminye imithi (eg, sorafenib). I-Cabozantinibtablet isetyenziswa futhi ekwelapheni lomdlavuza we-thyroid ohlukanisiwe osekuye wasakazeka ezingxenyeni ezahlukene zomzimba, kubantu abangase basaphathwa nge-radioactive iodine noma abangakwazi ukuthola i-radioactive iodine, futhi abake baphathwa ngeminye imithi (eg, ukwelashwa okuqondiswe yi-VEGFR) kodwa akusebenzi kahle. I-Cabozantinib iyimithi yokulwa nomdlavuza (cancer). Iphazamisa ukukhula kwamaselula omdlavuza, aqedwa ekugcineni umzimba. Lolu lwemi lusebenza kuphela ngomyalelo wochwepheshe wezokwelapha. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Uma kunquma ukusebenzisa imithi, kufanele kuqhathaniswe ingozi yokusebenzisa imithi nezinzuzo ezizoletha. Lo ngumqulu ozowenza wena nodokotela wakho. Kule mithi, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqakathekile noma oluhambisana nokwaleka kule mithi noma kunoma iyiphi enye imithi. Tshela futhi ochwepheshe bezempilo uma unezinye izinhlobo zokwaleka, njengokudla, izibhebhe, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ye-cabozantinib kubantwana abaneminyaka engaphansi kwengu-12 ubudala ukuze baphathwe ngomdlavuza we-thyroid ohlukanisiwe noma kubantwana ukuze baphathwe ngomdlavuza we-thyroid we-medullary, umdlavuza welaphe, nomdlavuza wezinso oqhutshwe. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingakhawulela ukusebenziseka kwe-cabozantinib tablets kubantu abadala. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela ye-cabozantinib capsules kubantu abadala. Noma kunjalo, azikho izinkinga ezikhethekile zabantu abadala ezibhalwe kuze kube manje. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokusebenzisa le mithi ngesikhathi sokuncelisa. Nakuba ezinye izimithi kufanele zingasetshenziswanga ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bezempilo bakwazi uma uthatha noma iyiphi imithi ehlwini elingezansi. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwawo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma iyiphi imithi elandelayo ngokuvamile akusikweliswa, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ezinye izimithi akufanele zisetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka kube khona ukusebenzisana. Ukusebenzisa utshwala noma utshaba nezinye izimithi kungabangela ukusebenzisana. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwawo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yini elandelayo ngokuvamile akusikweliswa, kodwa kungase kungakugwenyeki kwezinye izimo. Uma kusetshenziswa ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi uyayisebenzisa kangakanani le mithi, noma akunikeze imiyalo ekhethekile mayelana nokusetshenziswa kokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Imithi ebizwa ngokuthi i-Cabometyx® ne-Cometriq® isebenza kakhulu futhi ingaba nemiphumela emibi eminingi. Ngaphambi kokuthatha le mithi, qiniseka ukuthi uyayiqonda yonke imingcipheko nezinzuzo. Kubalulekile ukusebenzisana eduze nodokotela wakho ngesikhathi sokwelashwa kwakho. Thatha le mithi kuphela njengoba uqondiswe udokotela wakho. Ungayithathi ngaphezulu, ungayithathi kaningi, futhi ungayithathi isikhathi eside kunalokho oqondiswe udokotela wakho. Ukwenza kanjalo kungandisa amathuba emiphumela engathandeki. Le mithi ifika ne-insert yolwazi lwabaguli. Funda bese ulandela imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Ungayithathi indawo yamaphilisi e-Cabometyx® ngama-cabosantinib capsules. Ungayithathi indawo yama-Cometriq® capsules ngama-cabosantinib amaphilisi. Thatha le mithi isisu siyimile. Ungadli okungenani amahora angu-2 ngaphambi nangaphezulu kwehora eli-1 ngemuva kokuthatha le mithi. Gwinya le mithi yonke ngeglasi eligcwele (okungenani ama-ounces angu-8) amanzi. Ungayicwili, ungayaphula, ungayikunye, noma uvule i-capsule noma iphilisi. Ungadli i-grapefruit noma uphuze ijusi le-grapefruit ngenkathi usebenzisa le mithi. I-grapefruit nejusi le-grapefruit zingandisa inani lale mithi egazini. Inani lale mithi lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi ale mithi. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani lemithi oyithatha lixhomeke emandleni emithi. Futhi, inani lemithi oyithatha nsuku zonke, isikhathi esivunyelwe phakathi kwemithi, nobude besikhathi oyithatha imithi kuya ngenkinga yezokwelapha oyisebenzisela imithi. Uma uphuthelwa yidosi yale mithi, yithatha ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi sedosi yakho elandelayo, skip idosi ephuthelwe bese ubuyela esimweni sakho sokuthola imithi. Ungawandisi ama-doses. Uma uphuthelwa yidosi yale mithi futhi kungaphansi kwamahora angu-12 kuze kube yidosi yakho elandelayo ehlelwe, skip idosi ephuthelwe bese uthatha idosi yakho elandelayo ngesikhathi esivamile. Uma uphuthelwa yidosi futhi kungaphezulu kwamahora angu-12 kuze kube yidosi yakho elandelayo, yithatha ngokushesha okukhulu bese uthatha idosi yakho elandelayo ngesikhathi esivamile. Gcina imithi esitsheni esivaliwe ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungayivumeli ukuba iqhwaze. Gcina ingafinyeleleki kubantwana. Ungagcini imithi esele iphelile noma imithi engasadingeki. Buza ochwepheshe bakho bezempilo ukuthi kufanele uyilahla kanjani noma iyiphi imithi ongayisebenzisi.