Iyini i-Candesartan ne-Hydrochlorothiazide: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Candesartan ne-hydrochlorothiazide kuyinhlanganisela yomuthi wokwehlisa umfutho wegazi ohlanganisa izitha ezimbili ezinamandla empini yakho yokulwa nomfutho wegazi ophezulu. Lo muthi oqeda izinto ezimbili uhlanganisa i-ARB (i-angiotensin receptor blocker) ne-water pill ukusiza inhliziyo yakho isebenze kahle futhi igcine umfutho wegazi lakho ebangeni elinempilo.

Cabanga ngale nhlanganisela njengendlela yokusebenzisana yokuphatha impilo yakho yenhliziyo nemithambo yegazi. Ngenkathi i-candesartan isiza ukuphumuza imithambo yakho yegazi, i-hydrochlorothiazide ikhipha uketshezi oluningi emzimbeni wakho, isebenza ndawonye ukunciphisa ingcindezi enhliziyweni yakho nasemithanjeni yakho.

Iyini i-Candesartan ne-Hydrochlorothiazide?

Lo muthi uhlanganisa ukwelashwa okubili okusunguliwe komfutho wegazi okungena emthini owodwa olula. I-Candesartan ingeyeqembu lemithi ebizwa nge-ARBs, evimba amahomoni athile aqinisa imithambo yegazi. I-Hydrochlorothiazide iyi-thiazide diuretic, eyaziwa kakhulu njenge-water pill, esiza izinso zakho ukususa usawoti namanzi amaningi emzimbeni wakho.

Le nhlanganisela isebenza ngokubambisana, okusho ukuthi imithi emibili ithuthukisa ukusebenza kahle komunye nomunye. Lokhu kubambisana kuvame ukuvumela abantu ukuthi bathole ukulawulwa okungcono komfutho wegazi kunalokho abangase bakuthole ngomuthi owodwa kuphela.

Udokotela wakho angase akubhalele le nhlanganisela uma imithi eyodwa ingazange ilethe umfutho wegazi lakho emazingeni okuhlosiwe, noma uma udinga izinzuzo ezithile ezinikezwa yizo zombili izingxenye.

Isetshenziselwani i-Candesartan ne-Hydrochlorothiazide?

Lo muthi ohlanganisiwe ngokuyinhloko ubhalelwe ukwelapha umfutho wegazi ophezulu, obuye ubizwe nge-hypertension. Umfutho wegazi ophezulu uthinta cishe ingxenye yabantu abadala futhi uvame ukuthuthuka buthule eminyakeni eminingi ngaphandle kwezimpawu ezisobala.

Ngaphandle kokwehlisa izinombolo zomfutho wegazi, lo muthi usiza ukuvikela inhliziyo yakho, izinso, nemithambo yegazi ekulimaleni kwesikhathi eside. Uma umfutho wegazi lakho uhlala uphakeme, uphoqa inhliziyo yakho ukuthi isebenze kanzima futhi kungase kulimaze kancane kancane izicubu ezibucayi ohlelweni lwakho lwe-cardiovascular.

Abanye odokotela baphinda banikeze le nhlanganisela ukusiza ekuvikeleni ukuhlaselwa yinhliziyo, ukushaywa unhlangothi, nezinkinga zezinso esikhathini esizayo kubantu abanezici eziyingozi ze-cardiovascular. Isenzo esiphindwe kabili sinikeza ukuvikelwa okuphelele ohlelweni lwakho lokujikeleza kwegazi.

Isebenza Kanjani I-Candesartan kanye ne-Hydrochlorothiazide?

Le nhlanganisela yomuthi isebenza ngezindlela ezimbili ezihambisanayo zokwehlisa umfutho wegazi lakho ngempumelelo. I-Candesartan ivimba ama-angiotensin II receptors, ivimbela i-hormone evame ukubangela ukuthi imithambo yegazi inciphe futhi iqine.

Uma i-candesartan ivimba la ma-receptors, imithambo yakho yegazi ingakhululeka futhi yande, ivumele igazi ukuthi ligeleze kalula. Lokhu kunciphisa umfutho odongeni lwemithambo yakho futhi kwenza kube lula ukuthi inhliziyo yakho ipompe igazi emzimbeni wakho wonke.

Ngesikhathi esifanayo, i-hydrochlorothiazide isebenza ezinso zakho ukwandisa ukususwa kwe-sodium namanzi ngomchamo wakho. Njengoba uketshezi oluningi luphuma emzimbeni wakho, inani eliphelele legazi liyancipha, okunciphisa ngokwemvelo umfutho ngaphakathi kwemithambo yakho yegazi.

Lokhu kuthathwa njengenhlangano yomuthi womfutho wegazi oqinile ngokulinganisela. Indlela ephindwe kabili ivame ukunikeza imiphumela engcono kunokusebenzisa noma yimuphi umuthi ngawodwa, ikakhulukazi kubantu abomfutho wegazi labo ongazange uphendule ngokwanele emuthini owodwa.

Kufanele Ngiyithathe Kanjani I-Candesartan kanye ne-Hydrochlorothiazide?

Thatha lo muthi ngendlela eqondile udokotela wakho ayala ngayo, ngokuvamile kanye ngosuku ngesikhathi esifanayo nsuku zonke. Ungayithatha nokudla noma ngaphandle kokudla, nakuba abanye abantu bethola ukuthi ukuyithatha ngokudla okulula kusiza ukuvimbela noma yikuphi ukuphazamiseka kwesisu.

Gwinya ithebhulethi yonke ngengilazi yamanzi egcwele. Ungayichobozi, uyihlafune, noma uyihlukanise ithebhulethi, ngoba lokhu kungathinta indlela umuthi ogwinywa ngayo futhi ukhishwe emzimbeni wakho.

Ukwelapha ekuseni kuvame ukukhethwa ngoba ingxenye ye-hydrochlorothiazide ingase yandise ukuchama amahora amaningi. Ukuyithatha ekuseni kusiza ekuvikeleni ukuvakashela endlini yangasese ebusuku okungaphazamisa ukulala kwakho.

Uma udla usawoti omningi noma ukudla okucutshungulwayo, zama ukunciphisa ukudla kwakho i-sodium ngenkathi uthatha lo muthi. I-hydrochlorothiazide isebenza kangcono lapho umzimba wakho ungahlali ubhekana ne-sodium eningi evela ekudleni kwakho.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Candesartan kanye ne-Hydrochlorothiazide?

Abantu abaningi badinga ukuthatha lo muthi isikhathi eside ukuze bagcine amazinga omfutho wegazi enempilo. Umfutho wegazi ophezulu ngokuvamile uyisimo esingapheli esidinga ukuphathwa okuqhubekayo kunokwelashwa kwesikhashana.

Ungase uqale ukubona ukuthuthuka komfutho wegazi phakathi kwamasonto angu-2-4 ngemuva kokuqala ukwelashwa, kodwa kungathatha amasonto angu-6-8 ukuzwa izinzuzo eziphelele. Udokotela wakho uzoqapha inqubekela phambili yakho futhi angase alungise umthamo wakho ngalesi sikhathi.

Ungayeki ukuthatha lo muthi kungazelelwe, ngisho noma uzizwa ulungile. Umfutho wegazi ophezulu ngokuvamile awubangeli zimpawu, ngakho ukuzizwa ulungile akusho ukuthi awusadingi ukwelashwa. Ukuyeka kungazelelwe kungabangela umfutho wegazi wakho ukuthi ukhuphuke ngendlela eyingozi.

Udokotela wakho uzohlola njalo umfutho wegazi lakho, ukusebenza kwezinso, kanye namazinga e-electrolyte ukuze aqinisekise ukuthi umuthi uyaqhubeka usebenza ngokuphepha kuwe. Lokhu kuhlolwa kusiza ukunquma ukuthi ngabe udinga ukuqhubeka nomthamo ofanayo noma ukwenza izinguquko.

Yiziphi Imiphumela Eceleni ye-Candesartan kanye ne-Hydrochlorothiazide?

Abantu abaningi bayawuthola kahle lo muthi ohlanganisiwe, kodwa njengayo yonke imithi, ingabangela imiphumela emibi kwabanye abantu. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe uqiniseka ngokwengeziwe ngokuphathwa kwakho.

Nawa amanye amaphutha avamile ongase uhlangabezane nawo:

• Isiyezi noma ukukhathala, ikakhulukazi uma usukuma ngokushesha
• Ukunyuka kokuchama, ikakhulukazi emasontweni ambalwa okuqala
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile
• Ikhanda
• Isicanucanu noma isisu esibuhlungu
• Ama-cramps emisipha noma ubuthakathaka
• Umlomo owomile noma ukoma okwandayo

Le miphumela evamile ivame ukuthuthuka njengoba umzimba wakho ujwayela imithi emasontweni ambalwa okuqala. Ukunyuka kokuchama ngokuvamile kuba ngaphansi kokuqapheleka njengoba umzimba wakho uthola ibhalansi yawo entsha.

Abanye abantu bangase babe nemiphumela emibi kakhulu edinga ukunakekelwa kwezokwelapha. Xhumana nodokotela wakho uma uqaphela noma yiziphi zalezi zimpawu:

• Isiyezi esikhulu noma ukuquleka
• Ukushaya kwenhliziyo okungajwayelekile noma ubuhlungu besifuba
• Ubuthakathaka obukhulu bemisipha noma ama-cramps
• Ukudideka noma izinguquko zemizwa
• Ukuphuma kwegazi okungajwayelekile noma ukuqina
• Izimpawu zezinkinga zezinso njengokuncipha kokuchama noma ukuvuvukala
• Ukuphendula kwesikhumba okukhulu noma ukuqubuka

Imiphumela emibi engavamile kodwa ebucayi ingabandakanya ukusabela okukhulu komzimba, ukungasebenzi kahle kwezinso, noma izinguquko eziyingozi kumakhemikhali egazi lakho. Ngenkathi lezi zinkinga zingavamile, udokotela wakho uzokuqapha njalo ukuze abambe noma yiziphi izinkinga zisasekuqaleni.

Ubani Ongafanele Athole i-Candesartan ne-Hydrochlorothiazide?

Le mithi ehlanganisiwe ayifanele wonke umuntu, futhi udokotela wakho uzocabangela ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo eziningana nezimo zenza le mithi ingaphephile.

Akufanele uthathe le mithi uma unezimo ezithile zezempilo. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ukuze aqinisekise ukuthi lokhu kwelashwa kuphephile kuwe:

• Isifo esibi sezinso noma ukwehluleka kwezinso
• Isifo esibi sesibindi
• I-Anuria (ukungakwazi ukukhiqiza umchamo)
• Ukungezwani komzimba okwaziwayo kuma-ARBs, ama-thiazide diuretics, noma imithi ye-sulfa
• Ukungalingani okukhulu kwama-electrolyte
• Ukukhulelwa noma ukuhlela ukukhulelwa
• Ukuncelisa

Ezinye izimo zezokwelapha zidinga ukuqapha okwengeziwe nokuqapha okuseduze uma uthatha lo muthi. Udokotela wakho angase akwazi ukuku-oda kodwa uzokubheka ngokucophelela ngezinkinga ezingaba khona.

Abantu abanesifo sikashukela, i-gout, i-lupus, noma izinkinga zesigqi senhliziyo badinga ukucatshangelwa okukhethekile ngaphambi kokuqala le nhlanganisela. Udokotela wakho uzokala izinzuzo ngokumelene nezingozi futhi angase ayale ukuhlolwa okwengeziwe ukuze aqinisekise ukuphepha kwakho.

Amagama Omkhiqizo we-Candesartan kanye ne-Hydrochlorothiazide

Lo muthi ohlanganisiwe utholakala ngaphansi kwamagama amaningi omkhiqizo, i-Atacand HCT iyona engajwayelekile ukunconywa. Amanye amagama omkhiqizo afaka i-Atacand Plus kwamanye amazwe.

Izinhlobo ezivamile nazo ziyatholakala futhi ziqukethe izithako ezifanayo ezisebenzayo njengezinhlobo zegama lomkhiqizo. Imithi ejwayelekile ihlolwa ngokuqinile ukuze kuqinisekiswe ukuthi isebenza kahle njengozakwabo wegama lomkhiqizo.

I-pharmacy yakho ingashintsha inguqulo ejwayelekile ngaphandle uma udokotela wakho ecela ngokuqondile igama lomkhiqizo. Lokhu kushintshwa kungasiza ukunciphisa izindleko zakho zemithi ngenkathi kunikezwa izinzuzo ezifanayo zokwelapha.

Ezinye izindlela ze-Candesartan kanye ne-Hydrochlorothiazide

Eminye imithi ehlanganisiwe ingelapha umfutho wegazi ophezulu uma le nhlanganisela ethile ingasebenzi kahle kuwe. Udokotela wakho unezinye izindlela eziningi eziphumelelayo zokucabangela ngokuya ngezidingo zakho ezithile.

Ezinye izinhlanganisela ze-ARB zifaka i-valsartan/hydrochlorothiazide, i-losartan/hydrochlorothiazide, kanye ne-olmesartan/hydrochlorothiazide. Le mithi isebenza ngendlela efanayo kodwa ingase ikufanele kangcono uma uhlangabezana nemiphumela emibi nge-candesartan.

Izinhlanganisela ze-ACE inhibitor ezifana ne-lisinopril/hydrochlorothiazide noma i-enalapril/hydrochlorothiazide zinikeza enye inketho. Lezi zisebenza ngendlela ehluke kancane kune-ARBs kodwa zivame ukukhiqiza izinzuzo ezifanayo zomfutho wegazi.

Udokotela wakho angase futhi acabangele izinhlanganisela ezinohlobo oluhlukile lwama-diuretics noma angeze umuthi wesithathu uma izinhlanganisela zemithi emibili zinganele. Okubalulekile ukuthola inhlanganisela efanele elawula umfutho wakho wegazi ngemiphumela emincane.

Ingabe i-Candesartan ne-Hydrochlorothiazide Ingcono Kune-Losartan ne-Hydrochlorothiazide?

Zombili lezi zinhlanganisela ziyimithi esebenzayo yomfutho wegazi, kodwa i-candesartan/hydrochlorothiazide ingase inikeze ezinye izinzuzo ngaphezu kwe-losartan/hydrochlorothiazide kwabanye abantu. Ukukhetha kuvame ukuncika ekuphenduleni kwakho ngakunye kanye nomlando wezokwelapha.

I-Candesartan ngokuvamile inikeza ukulawulwa komfutho wegazi okuhlala isikhathi eside, ngokuvamile igcina ukusebenza amahora angama-24 ngokugcwele ngomthamo kanye ngosuku. Ezinye izifundo zikhomba ukuthi i-candesartan ingase ibangele imiphumela emincane efana nokukhwehlela noma isiyezi uma iqhathaniswa ne-losartan.

Kodwa-ke, i-losartan isitholakala isikhathi eside futhi inocwaningo oluningi olusekela ukuphepha kwayo nokusebenza kwayo. Futhi ngokuvamile ibiza kancane kune-candesartan, okungaba kubalulekile ekwelashweni kwesikhathi eside.

Udokotela wakho uzocabangela izinto ezinjengokusebenza kwezinso zakho, eminye imithi oyithathayo, nokuthi ukubekezelela kahle kangakanani inketho ngayinye. Okusebenza kahle kumuntu oyedwa kungase kungabi kuhle komunye, ngakho ukwelashwa komuntu ngamunye kubalulekile.

Imibuzo Evame Ukubuzwa Mayelana ne-Candesartan ne-Hydrochlorothiazide

Ingabe i-Candesartan ne-Hydrochlorothiazide Iphephile Esinso?

Le nhlanganisela idinga ukucatshangelwa ngokucophelela uma unesifo sezinso. Ngenkathi ama-ARBs afana ne-candesartan empeleni angasiza ukuvikela izinso kubantu abanesifo sikashukela nesifo sezinso esingathí sina, yomibili imithi ingathinta ukusebenza kwezinso.

Uma unezifo eziphakathi nendawo kuya kweziphakathi zokugula izinso, udokotela wakho angase akwazi ukukuyala le nhlanganisela kodwa uzoqapha ukusebenza kwezinso zakho ngokucophelela ngezivivinyo zegazi ezivamile. Izinzuzo zokulawulwa komfutho wegazi zivame ukwedlula izingozi kubantu abanezifo eziqala ezinso.

Nokho, uma unezifo ezinzima ezinso noma ukwehluleka kwezinso, le nhlanganisela ngokuvamile ayinconyelwe. Udokotela wakho uzodinga ukukhetha imithi ehlukile ephephezelayo ezinso zakho.

Kufanele ngenzeni uma ngithatha i-Candesartan ne-Hydrochlorothiazide ngengozi eningi kakhulu?

Uma ngengozi uthatha ngaphezu komthamo wakho obekiwe, ungapheli amandla, kodwa thatha isinyathelo ngokushesha. Xhumana nodokotela wakho, usokhemisi, noma isikhungo sokulawula ubuthi ngokushesha ukuze uthole isiqondiso sokuthi wenzeni ngokulandelayo.

Ukweqisa kungase kubangele umfutho wegazi ophansi kakhulu, okuholela ekugxumeni, ukuquleka, noma ubunzima bokuhlala unomqondo. Ungase futhi uhlangabezane nokuphelelwa amanzi emzimbeni, ukungalingani kwe-electrolyte, noma izinkinga zezinso ngenxa yomphumela omningi we-diuretic.

Ungazami ukuzenza uhlanze noma uthathe eminye imithi ukuze ulwe nokweqisa. Kunalokho, funa ukunakekelwa kwezokwelapha ngokushesha, ikakhulukazi uma uzizwa unesiyezi, ubuthakathaka, noma udidekile.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Candesartan ne-Hydrochlorothiazide?

Uma uphuthelwa umthamo, thatha ngokushesha lapho ukhumbula, ngaphandle kwalapho sekuseduze nesikhathi somthamo wakho olandelayo ohleliwe. Ungathathi imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, njengoba lokhu kungase kubangele umfutho wegazi lakho ukuthi wehle kakhulu.

Uma ukhumbula sekwephuze emini, ungase ufune ukweqa umthamo ophuthelwe bese uqala kabusha uhlelo lwakho olujwayelekile ngosuku olulandelayo. Ukuthatha ingxenye ye-diuretic sekwephuze emini kungase kuphazamise ukulala kwakho ngokuchama ebusuku.

Zama ukusungula inqubo ekusiza ukuthi ukhumbule umthamo wakho wansuku zonke, njengokuthi uwuthathe ngesidlo sasekuseni noma ukusetha isikhumbuzi sefoni. Ukulinganisa kwansuku zonke okungaguquki kusiza ukugcina ukulawulwa komfutho wegazi okuzinzile.

Ngingayeka nini ukuthatha i-Candesartan ne-Hydrochlorothiazide?

Kufanele uyeke ukuthatha lo muthi ngaphansi kokuqondiswa ngudokotela wakho. Umfutho wegazi ophezulu ngokuvamile uyisimo sempilo yonke esidinga ukwelashwa okuqhubekayo, ngisho nalapho uzizwa uphilile ngokuphelele.

Udokotela wakho angase acabange ukunciphisa umthamo wakho noma ashintshe imithi uma ugcine ukulawulwa okuhle komfutho wegazi isikhathi eside futhi wenza izinguquko ezinkulu zokuphila. Kodwa-ke, ukuyeka ngokuphelele akuvamile ukunconywa.

Uma ukhathazekile ngokusebenzisa imithi yesikhathi eside, xoxa ngokukhathazeka kwakho nodokotela wakho. Bangakusiza ukuthi uqonde izinzuzo zokuqhubeka nokwelashwa futhi babhekane nanoma yikuphi ukukhathazeka mayelana nemiphumela emibi noma ukuxhumana.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Candesartan ne-Hydrochlorothiazide?

Ukuphuza utshwala ngokulinganisela kuvamile ukwamukeleka ngenkathi uthatha lo muthi, kodwa kufanele uxoxe ngokusebenzisa utshwala nodokotela wakho. Kokubili utshwala kanye nalo muthi kunganciphisa umfutho wegazi, ngakho ukuzihlanganisa kungase kubangele ukwehla okukhulu komfutho wegazi.

Uma ukhetha ukuphuza utshwala, kwenze ngokulinganisela futhi unake indlela ozizwa ngayo. Ungase uzwe isiyezi esiningi noma ukukhanya kwekhanda kunokujwayelekile, ikakhulukazi uma usukuma ngokushesha.

Ingxenye ye-diuretic nayo ingakhuphula ingozi yokuphelelwa amanzi emzimbeni, futhi utshwala bungase buqhubekisele phambili le nhlobo. Qiniseka ukuthi uhlala unamanzi kahle uma uphuza utshwala ngenkathi uthatha lo muthi.