Yini i-Cannabidiol (CBD): Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Cannabidiol, eyaziwa kakhulu nge-CBD, iyinhlanganisela yemvelo etholakala ezitshalweni zecannabis ezingakwenzi uzizwe “uphezulu” njengoba i-THC yenza. Lo muthi omnene, ongaqedi umzimba uthole ukunakwa ngenxa yamandla awo okusiza ngezimo ezithile zezokwelapha, ikakhulukazi izifo zokuhlaselwa yizithuthwane ezinganeni nakubantu abadala.

Ngokungafani ne-marijuana yokuzilibazisa, i-CBD kadokotela iqukethe amanani alinganiselwe ngqo esithako esisebenzayo. I-FDA ivume umuthi owodwa othile we-CBD obizwa nge-Epidiolex wokwelapha izinhlobo ezingavamile ze-epilepsy, inikeza imindeni nodokotela inketho yokwelapha ethembekile esekelwe ocwaningweni lwezempilo.

Yini i-Cannabidiol Esetshenziselwa Yona?

I-CBD ikakhulukazi inikezwa ngemithi yezinhlobo ezithile zezifo zokuhlaselwa yizithuthwane okunzima ukuzilawula ngemithi yendabuko. Ukusetshenziswa okuyinhloko okuvunyelwe kufaka phakathi i-Lennox-Gastaut syndrome kanye ne-Dravet syndrome, izinhlobo ezimbili ezingavamile kodwa ezinzima ze-epilepsy ezivame ukuqala ebuntwaneni.

Lezi zimo zingabangela ukuhlaselwa yizithuthwane ezivame kakhulu, ezinzima ezinomthelela omkhulu empilweni yansuku zonke nasekukhuleni. Eminzaneni ebhekene nalezi zifo eziyinselele, i-CBD inikeza ithemba lapho ezinye izindlela zokwelapha zingazange zinikeze ukulawulwa okwanele kokuhlaselwa yizithuthwane.

Abanye odokotela bangase futhi banikeze i-CBD ye-tuberous sclerosis complex, esinye isimo esingavamile esingabangela ukuhlaselwa yizithuthwane. Ucwaningo luqhubeka kwezinye izindlela ezingaba khona zokusebenzisa, kodwa njengamanje, izifo zokuhlaselwa yizithuthwane zihlala ziyisicelo esiyinhloko sezokwelapha se-CBD kadokotela.

Isebenza Kanjani i-Cannabidiol?

I-CBD isebenza ngokuxhumana nesistimu yakho ye-endocannabinoid yomzimba, inethiwekhi yezamukeli ezisiza ukulawula imisebenzi ehlukahlukene ehlanganisa umsebenzi wobuchopho. Cabanga ngayo njengokulungisa ngobumnene umsebenzi kagesi ebuchosheni bakho ukunciphisa amathuba okuthi ukuhlaselwa yizithuthwane kwenzeke.

Lo muthi ubhekwa njengonamandla amaphakathi, okusho ukuthi ungasebenza kahle ezimweni ezifanele ngaphandle kokuba namandla kakhulu. Ngokungafani neminye imithi yokulwa nokuthuthumela engabangela ukozela okukhulu noma imiphumela yengqondo, i-CBD ivame ukuba nomthelela omnene ekusebenzeni kwansuku zonke.

Indlela eqondile ayikaqondwa ngokugcwele okwamanje, kodwa ucwaningo luphakamisa ukuthi i-CBD isiza ukuzinzisa umsebenzi wamaseli ezinzwa ebuchosheni. Lokhu kuzinza kunganciphisa kakhulu kokubili ukuvama nobukhulu bokuthuthumela ezigulini eziningi.

Kufanele Ngiyithathe Kanjani I-Cannabidiol?

Isixazululo somlomo se-CBD kufanele sithathwe ngendlela eqondile njengoba kunqunywe udokotela wakho, ngokuvamile kabili ngosuku ngokudla. Ukuyithatha ngokudla, ikakhulukazi okunezinye izinto ezinamafutha, kusiza umzimba wakho ukuba umunce umuthi ngempumelelo.

Uzothola i-CBD njengoketshezi olulinganisa ngokucophelela usebenzisa isirinji yomlomo enikeziwe. Uketshezi lungagwinywa ngokuqondile noma luxutshwe ekudleni okuthambile njenge-applesauce noma i-pudding uma ukunambitheka kuyinkinga, ikakhulukazi ezinganeni.

Njalo sebenzisa idivayisi yokulinganisa eza ngemiyalelo yakho kunokuba usebenzise izipuni zasendlini. Gcina ibhodlela esiqandisini bese ulithuthumisa ngobumnene ngaphambi kwesilinganiso ngasinye ukuze uqinisekise ukuthi umuthi uxutshwe kahle.

Zama ukuthatha imithamo yakho ngezikhathi ezifanayo nsuku zonke ukuze ugcine amazinga aqinile ohlelweni lwakho. Uma futhi uthatha eminye imithi yokulwa nokuthuthumela, qhubeka naleyo njengoba kuqondisiwe ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze izinguquko.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Cannabidiol?

Ubude bokwelashwa kwe-CBD buhlukahluka kakhulu kuye ngesimo sakho esithile nokuthi usabela kahle kangakanani emuthini. Ukuze kulawulwe isithuthwane, abantu abaningi badinga ukuthatha i-CBD isikhathi eside ukuze balondoloze ukulawulwa kokuthuthumela, ngezinye izikhathi iminyaka.

Udktela wakho ngokuvamile uzoqala ngomthamo ophansi bese ewunyusa kancane kancane emasontweni amaningana ngenkathi eqapha impendulo yakho. Le ndlela eqaphelayo isiza ukunciphisa imiphumela emibi ngenkathi ithola umthamo osebenzayo kakhulu esimweni sakho.

Ukuqokwa okulandelayo njalo kubalulekile ukuhlola ukuthi umuthi usebenza kahle kangakanani nokuthi ngabe kukhona yini okudingeka kulungiswe. Udokotela wakho uzophinda aqaphe imiphumela emibi engaba khona nokusebenzisana neminye imithi ongase uyithathe.

Ungayeki ukuthatha i-CBD ngokuzumayo, ngoba lokhu kungaholela ekwandeni komsebenzi wokuhlaselwa. Uma udinga ukuyeka umuthi, udokotela wakho uzokwenza isimiso sokunciphisa kancane kancane ukuze unciphise ngokuphepha umthamo wakho ngokuhamba kwesikhathi.

Yini Imiphumela Emibi ye-Cannabidiol?

Abantu abaningi bayayibekezelela i-CBD kahle, kodwa njengayo yonke imithi, ingabangela imiphumela emibi kwabanye abantu. Izindaba ezinhle ukuthi imiphumela emibi engathi sína ayivamile, futhi imiphumela eminingi emincane iyathuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi evame kakhulu ongase uyithole:

• Ukozela noma ukukhathala, ikakhulukazi lapho uqala ukwelashwa
• Ukuncipha kwesifiso sokudla noma izinguquko emikhubeni yokudla
• Ukuqunjelwa noma izitulo ezixekile
• Ushintsho lwemizwa, okuhlanganisa ukucasuka noma ukuthukuthela
• Ukuphazamiseka kokulala noma izinguquko emaphethini okulala
• Ukuqubuka kwesikhumba okuncane noma ukuluma

Le miphumela ejwayelekile ivame ukuncipha njengoba umzimba wakho ujwayela umuthi, ngokuvamile kungakapheli amasonto ambalwa uqale ukwelashwa.

Ngenkathi kungavamile, abanye abantu bangase babe nemiphumela ebaluleke kakhulu edinga ukunakekelwa kwezokwelapha:

• Ushintsho lomsebenzi wesibindi, okuzoqashwa udokotela wakho ngezivivinyo zegazi
• Ukuncipha okukhulu kwesisindo noma ukulahlekelwa isifiso sokudla okuqhubekayo
• Ushintsho olukhulu lwemizwa noma imicabango yokuzilimaza
• Ukuphuma kwegazi okungajwayelekile noma ukulimala
• Izimpawu zokutheleleka njengomkhuhlane noma ukukhathala okuqhubekayo

Xhumana nomhlinzeki wakho wezempilo uma uqaphela noma yiziphi izimpawu ezikhathazayo noma uma imiphumela emibi iphazamisa imisebenzi yakho yansuku zonke. Izinkinga eziningi zingalawulwa ngokulungisa umthamo wakho noma isikhathi.

Ubani Ongafanele Athathwe I-Cannabidiol?

Ngenkathi i-CBD ngokuvamile iphephile kubantu abaningi, abantu abathile kufanele bagweme lo muthi noma bawuse ngokucophelela okwengeziwe. Udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokubhala i-CBD ukuze aqinisekise ukuthi ifanele isimo sakho.

Abantu abanezinkinga zesibindi ezikhona kufanele baqaphele kakhulu, njengoba i-CBD ingathinta ukusebenza kwesibindi. Udokotela wakho cishe uzo-oda ukuhlolwa kwegazi ukuze ahlolisise ama-enzyme esibindi ngaphambi kokuqala ukwelashwa kanye ngezikhathi ezithile ngesikhathi sokwelashwa.

Nazi izimo lapho i-CBD ingase inganconywa khona:

• Ukungezwani okwaziwayo ne-CBD noma yiziphi izingxenye zomuthi
• Isifo sesibindi esibi noma ama-enzyme esibindi aphakanyiswe kakhulu
• Njengamanje uthatha imithi ethile exhumana ne-CBD
• Umlando wezimo ezingokwengqondo ezingathi sína ezingase zibe zimbi ngokwelashwa
• Ukukhulelwa noma ukuncelisa, njengoba imiphumela ezinganeni ezisakhulayo ingaziwa ngokugcwele

Uma uthatha eminye imithi, ikakhulukazi eminye imithi yokuhlaselwa yisithuthwane, ama-blood thinners, noma imithi ethile yenhliziyo, udokotela wakho uzodinga ukukuqapha eduze ukuze uthole ukuxhumana okungenzeka.

Amagama Omkhiqizo we-Cannabidiol

Okwamanje kuphela umuthi we-CBD ovunyelwe yi-FDA obizwa nge-Epidiolex, okhiqizwa yi-Greenwich Biosciences. Le yindlela odokotela abayibhala ngayo ukwelapha izifo zokuhlaselwa yisithuthwane, futhi yiwona kuphela umkhiqizo we-CBD oye wahlolwa ngokucophelela emitholampilo ukuze kutholakale ukuphepha nokusebenza.

I-Epidiolex iza njengesixazululo somlomo esinokugxila okucacile kwe-CBD, okuqinisekisa ukulinganisa okungaguquki kanye nekhwalithi. Lo mkhiqizo wezinga lezemithi uhluke kakhulu emikhiqizweni ye-CBD ongayithola ezitolo noma ku-inthanethi, engalawulwa yi-FDA.

Uma udokotela wakho ekunika imithi ye-CBD, uzobhala ngqo i-Epidiolex ukuqinisekisa ukuthi uthola imithi ehloliwe, ethembekile. Imikhiqizo ye-CBD etholakala ngaphandle kwemvume kadokotela iyahlukahluka kakhulu ngomgangatho nangokugxila kwayo, okuyenza ingafaneleki ekuphatheni izimo ezingathi sína zezokwelapha.

Ezinye Izindlela Zokwelapha Nge-Cannabidiol

Uma i-CBD ingafaneleki esimweni sakho noma inganikezi ukulawulwa okwanele kokuhlaselwa yisithuthwane, eminye imithi eminingi ingasiza ekuphatheni isithuthwane. Udokotela wakho uzosebenza nawe ukuthola indlela engcono kakhulu yokwelapha uhlobo lwakho oluthile lokuhlaselwa yisithuthwane.

Imithi yendabuko yokuhlaselwa yisithuthwane engase icatshangelwe ihlanganisa:

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• I-Valproic acid (Depakote) - isebenza kahle ezinhlotsheni eziningi zokuhlaselwa yisithuthwane kodwa idinga ukuqashwa
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• I-Levetiracetam (Keppra) - itholakala kahle enezinkinga ezimbalwa zemithi
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• I-Lamotrigine (Lamictal) - ilungele izinhlobo ezahlukene zokuhlaselwa yisithuthwane enemiphumela emincane engalawuleki
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• I-Topiramate (Topamax) - iyasebenza kodwa ingase ibangele imiphumela emibi yokuqonda
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• I-Clobazam (Onfi) - ilungele ikakhulukazi i-Lennox-Gastaut syndrome
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Kwabanye abantu, ukuhlanganisa i-CBD nemithi yendabuko yokuhlaselwa yisithuthwane kusebenza kangcono kunanoma iyiphi indlela yodwa. Udokotela wakho angase futhi acabangele ezinye izindlela zokwelapha ezikhethekile njengokuvuselelwa kwemizwa ye-vagus noma ukwelashwa kokudla ezimweni ezithile.

Ingabe i-Cannabidiol Ingcono Kunezinye Izindlela Zokwelapha Zokuhlaselwa Yisithuthwane?

I-CBD akudingeki ukuthi

Noma kunjalo, imithi yezinso yendabuko ineminyaka eminingi yocwaningo ngemuva kwayo futhi isebenza kahle kakhulu kubantu abaningi. Ezinye zishibhile kune-CBD futhi zinezikhombisi-ndlela zokulinganisa ezisungulwe kahle zamaqembu ahlukene obudala nezinhlobo zezinso.

Udokotela wakho uzocabangela izinto ezinjengendlela yakho yezinso, eminye imithi oyithathayo, nendlela yakho yokuphila lapho enquma ukuthi i-CBD noma enye imithi ingasebenza kangcono kuwe.

Imibuzo Evame Ukubuzwa Mayelana ne-Cannabidiol

Umbuzo 1. Ingabe i-Cannabidiol iphephile ezinganeni?

Yebo, i-CBD ivunyelwe yi-FDA ezinganeni ezineminyaka emi-2 ubudala ezinohlobo oluthile lwesithuthwane. Izivivinyo zomtholampilo ezaholela ekuvunyelweni yi-FDA zihlanganisa izingane eziningi, futhi imithi ikhombise imiphumela emihle yokuphepha ezigulini ze-pediatric.

Izingane ngokuvamile zikwazi ukumelana ne-CBD kahle, nakuba zingase zibe neminye yemiphumela emibi efanayo nabantu abadala, njengokozela noma ukuncipha kwesifiso sokudla. Ukulinganisa kwe-Pediatric kubalwa ngokucophelela ngokuya ngesisindo somzimba, futhi ukuqapha njalo kusiza ukuqinisekisa ukwelashwa okuphephile nokusebenzayo.

Umbuzo 2. Kufanele ngenzeni uma ngisebenzisa i-Cannabidiol eningi ngengozi?

Uma ngengozi uthatha i-CBD eningi kunaleyo ebekiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ngenkathi ukweqisa kwe-CBD kungavamile ukuba yingozi, ukuthatha okuningi kungabangela ukwanda kokozela, ukudideka, noma ukuphazamiseka kokugaya ukudla.

Ungazami ukuthi "ulungise" umthamo owengeziwe ngokuqaqa owakho olandelayo. Kunalokho, buyela esimisweni sakho sokulinganisa esivamile futhi wazise umhlinzeki wakho wezempilo ukuthi kwenzekeni ukuze akwelule ngezinyathelo ezilandelayo.

Umbuzo 3. Kufanele ngenzeni uma ngiphuthelwa umthamo we-Cannabidiol?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho evamile - ungaphindi ukuze ulungise umthamo ophuthelwe.

Zama ukugcina ukulinganisa okungaguquki ngokumisa izikhumbuzi zocingo noma uthathe imithi yakho ngesikhathi esifanayo nsuku zonke. Uma uvame ukukhohlwa imithamo, khuluma nodokotela wakho ngamasu okuthuthukisa ukunamathela emithini.

Q4. Ngingayeka nini Ukuthatha i-Cannabidiol?

Ungalokothi uyeke ukuthatha i-CBD ngokuzumayo ngaphandle kokubonisana nodokotela wakho kuqala. Ukuyeka imithi yokulwa nokuthimula ngokuphazima kweso kungabangela ukuthimula okusha, okungaba yingozi. Udokotela wakho uzokwenza isimiso sokunciphisa kancane uma udinga ukuyeka umuthi.

Isinqumo sokuyeka i-CBD sincike ezintweni ezifana nokuthi ukuthimula kwakho kulawulwa kahle kangakanani, imiphumela emibi oyitholayo, kanye nemigomo yakho yokwelashwa iyonke. Lesi sinqumo kufanele senziwe ngaso sonke isikhathi ngokubambisana nomhlinzeki wakho wezempilo.

Q5. Ngingashayela ngenkathi ngithatha i-Cannabidiol?

I-CBD ingabangela ukozela, ikakhulukazi uma uqala ukuyithatha noma uma umthamo wakho ukhuphuka. Kufanele ugweme ukushayela noma ukusebenzisa imishini kuze kube yilapho wazi ukuthi i-CBD ikuthinta kanjani wena.

Abantu abaningi bathola ukuthi noma yikuphi ukozela kuthuthuka ngemva kwamasonto ambalwa okwelashwa. Nokho, uma uqhubeka uzizwa ukozela noma uhlangabezana nezinye izimpawu ezingase ziphazamise ikhono lakho lokushayela ngokuphepha, xoxa ngalokhu nodokotela wakho kunokucabanga ukuthi kuzozixazulula ngokwazo.