Yini i-Capreomycin: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Capreomycin iyisijovo esinamandla se-antibiotic esisetshenziselwa ukwelapha i-tuberculosis (TB) lapho eminye imithi ingasebenzi kahle. Lo muthi ungoweqembu lemithi ebizwa ngokuthi ama-antibiotics e-peptide cyclic, asebenza ngokumisa ukukhula kwamagciwane e-TB emzimbeni wakho.

Udkt wakho uvame ukunquma i-capreomycin njengengxenye yohlelo lokwelapha oluhlanganisiwe uma une-tuberculosis engamelani nemithi. Cabanga ngayo njengethuluzi elikhethekile elisetshenziswa abahlinzeki bezempilo lapho imithi ejwayelekile ye-TB idinga ukwesekwa okwengeziwe ukulwa naleli gciwane.

Yini i-Capreomycin Esetshenziselwa Yona?

I-Capreomycin iphatha i-tuberculosis, ikakhulukazi lapho amagciwane esemelana nemithi ye-TB yomugqa wokuqala efana ne-isoniazid noma i-rifampin. Lokhu kuyenza lokho odokotela abakubiza ngokuthi inketho yokwelapha ye-TB "yomugqa wesibili".

Lo muthi ubaluleke kakhulu ekwelapheni i-tuberculosis emelana nemithi eminingi (MDR-TB). Lapho amagciwane e-TB engasabeli ekwelashweni okujwayelekile, i-capreomycin ingasiza umzimba wakho ukuthi ulwe naleli gciwane ngempumelelo.

Umhlinzeki wakho wezempilo uzohlala esebenzisa i-capreomycin kanye neminye imithi ye-TB. Le ndlela yokuhlanganisa isiza ekuvikeleni amagciwane ekuthuthukiseni ukumelana ne-capreomycin ngokwayo futhi yandisa amathuba akho okuphumelela ekwelashweni.

Isebenza Kanjani i-Capreomycin?

I-Capreomycin isebenza ngokungenelela ngendlela amagciwane e-TB enza ngayo amaprotheni abawadingayo ukuze basinde futhi bazale. Ibopha ezingxenyeni ezithile zomshini wokwenza amaprotheni wamagciwane, empeleni iphazamisa ikhono lawo lokusebenza kahle.

Lo muthi ubhekwa njenge-antibiotic enamandla, okusho ukuthi ingasebenza kahle kakhulu ngamagciwane e-TB. Kodwa-ke, amandla ayo asho nokuthi idinga ukuqashwa ngokucophelela yithimba lakho lezempilo ukuze kuqinisekiswe ukuthi lisebenza ngokuphepha.

Umjovo uletha imithi ngqo emithanjeni yakho yegazi, okuyivumela ukuthi ifinyelele ezindaweni ezinomkhuhlane emzimbeni wakho wonke. Le ndlela yokuletha ngqo isiza ekuqinisekiseni ukuthi imithi ifinyelela emazingeni asebenzayo lapho uyidinga kakhulu.

Kufanele Ngiyithathe Kanjani I-Capreomycin?

I-Capreomycin inikezwa njengomjovo emsipheni wakho, ngokuvamile engalweni yakho engenhla noma endaweni ye-hip. Uchwepheshe wezempilo uzohlala ekunikeza lo mjovo - ngeke kudingeke ukuthi uwulungiselele noma uziqhubeke wena.

Ngokuvamile uzothola umjovo kanye ngosuku, nakuba udokotela wakho angase alungise isimiso ngokusekelwe esimweni sakho esithile. Isikhathi singaba esiguquguqukayo, kodwa ukuqina kusiza ukugcina amazinga aqhubekayo emithi ohlelweni lwakho.

Akudingeki ukhathazeke ngokuthatha le mithi nokudla noma ngaphandle kokudla ngoba inikezwa njengomjovo. Nokho, ukuhlala unamanzi ngokwanele ngokuphuza amanzi amaningi kungasiza izinso zakho ukuthi zicubungule imithi ngempumelelo.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Capreomycin?

Ukwelashwa nge-capreomycin ngokuvamile kuthatha phakathi kwezinyanga ezi-4 kuya kwezi-6, nakuba lokhu kungahluka kakhulu ngokuya ngendlela umzimba wakho osabela ngayo ekwelashweni. Udokotela wakho uzoqapha inqubekela phambili yakho ngokusebenzisa izivivinyo ezivamile futhi alungise ubude ngokufanele.

Ubude bokwelashwa buxhomeke ezintweni eziningana ezihlanganisa ubunzima bokutheleleka kwakho nge-TB nokuthi usabela kahle kangakanani ekuhlanganisweni kwemithi. Abanye abantu bangase badinge ukwelashwa isikhathi esifushane, kanti abanye bangase badinge izifundo ezinde.

Ithimba lakho lezempilo lizohlola njalo isputum sakho (i-mucus evela emaphashini akho) nezinye izivivinyo ukuze libone ukuthi ukwelashwa kusebenza kahle kangakanani. Uma lezi zivivinyo zikhombisa ukuthi amagciwane e-TB awasatholakali, udokotela wakho angathatha isinqumo sokuthi kuphephile nini ukuyeka imithi.

Yiziphi Imiphumela Eceleni Ye-Capreomycin?

Njengazo zonke izidakamizwa ezinamandla, i-capreomycin ingabangela imiphumela emibi, nakuba kungewona wonke umuntu oyitholayo. Ukuqonda ukuthi yini okufanele uyibheke kukusiza wena nethimba lakho lezempilo ukuthi liphathe ukwelashwa kwakho ngokuphepha.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa ubuhlungu, ukuvuvukala, noma ububomvu endaweni yokujova. Lezi zimo zendawo ngokuvamile zithambile futhi zesikhashana, zithuthuka njengoba umzimba wakho ujwayela ukwelashwa.

Imiphumela Evamile Emibi

Nansi imiphumela emibi eyenzeka kaningi ngokuphathwa kwe-capreomycin:

• Ubuhlungu noma ukuqaqamba endaweni yokujova
• Ushintsho oluncane lokuzwa noma ukukhala ezindlebeni zakho
• Isiyezi noma izinkinga zokulinganisela
• Isicanucanu noma isisu esicasukile
• Ikhanda
• Ukukhathala noma ukuzizwa ukhathele kunokujwayelekile

Le miphumela emibi evamile ngokuvamile iyalawuleka futhi ivame ukuthuthuka njengoba umzimba wakho ujwayela imithi. Ithimba lakho lezempilo linganikeza amasu okusiza ukunciphisa noma yikuphi ukungakhululeki okutholayo.

Imiphumela Emibi Engathi Sína

Nakuba ingavamile, eminye imiphumela emibi idinga ukunakekelwa kwezokwelapha ngokushesha. Lezi zimo ezingathi sína zidinga ukuhlolwa ngokushesha ngumhlinzeki wakho wezempilo:

• Ukulahlekelwa ukuzwa okukhulu noma ukukhala okukhulu ezindlebeni
• Isiyezi esikhulu noma ukulahlekelwa ukulinganisela
• Izimpawu zezinkinga zezinso (ushintsho ekuchameni, ukuvuvukala emilenzeni noma ezinyaweni)
• Ukuphendula okukhulu komzimba (ubunzima bokuphefumula, ukuvuvukala ebusweni noma emqaleni)
• Ukuphuma kwegazi okungavamile noma ukulimala
• Ubuthakathaka obukhulu bemisipha

Uma uthola noma iyiphi yale miphumela emibi engathi sína, xhumana nomhlinzeki wakho wezempilo ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo. Ukungenelela kwasekuqaleni kungavimbela izinkinga futhi kuqinisekise ukuphepha kwakho.

Imiphumela Emibi Engavamile Kodwa Ebalulekile

Eminye imiphumela emibi yenzeka kaningi kodwa kubalulekile ukuyiqaphela:

• Ukulahlekelwa ukuzwa okuphelele (ubumpumputhe obungapheli)
• Umonakalo omkhulu wezinso odinga i-dialysis
• Ukuvinjelwa kwemisipha (ubuthakathaka obukhulu bemisipha obuthinta ukuphefumula)
• Ukungalingani okukhulu kwama-electrolyte
• Izifo zegazi ezithinta ukujiya kwegazi

Lezi zinkinga ezingavamile yizona ezenza udokotela wakho akuqaphele eduze ngaso sonke isikhathi sokwelashwa ngezivivinyo zokuzwa ezivamile, ukuhlolwa komsebenzi wezinso, kanye nomsebenzi wegazi.

Ubani Ongafanele Athole I-Capreomycin?

I-Capreomycin ayifanele wonke umuntu, futhi udokotela wakho uzohlola ngokucophelela ukuthi iphephile yini kuwe. Izimo ezithile zempilo noma izimo zenza lo muthi ungafaneleki noma zidinga izinyathelo zokuphepha ezikhethekile.

Uma unesifo esibi sezinso, udokotela wakho angase agweme i-capreomycin noma alungise kakhulu umthamo wakho. Njengoba izinso zakho zisebenzisa lo muthi, ukungasebenzi kahle kwezinso kungaholela ekwakhekeni okuyingozi ohlelweni lwakho.

Abantu abanezinkinga zokuzwa ezikhona noma umlando wokulahlekelwa ukuzwa badinga ukucatshangelwa okukhethekile. I-Capreomycin ingenza izinkinga zokuzwa zibe zimbi kakhulu, ngakho udokotela wakho uzolinganisela izinzuzo nezingozi ngokucophelela.

Izimo Ezidinga Ukuqapha

Umhlinzeki wakho wezempilo uzokuqapha eduze uma unanoma yiziphi zalezi zimo:

• Isifo sezinso noma ukuncipha komsebenzi wezinso
• Izinkinga zokuzwa noma umlando womndeni wokulahlekelwa ukuzwa
• Ukungalingani noma izifo zendlebe yangaphakathi
• Izifo zobuthakathaka bemisipha njenge-myasthenia gravis
• Ukungalingani kwama-electrolyte
• Ukukhulelwa noma ukuncelisa ibele

Ukuba nalezi zimo akusho ngokuzenzakalelayo ukuthi awukwazi ukwelashwa nge-capreomycin, kodwa kusho ukuthi udokotela wakho uzodinga ukukuqapha ngokucophelela futhi mhlawumbe alungise uhlelo lwakho lokwelashwa.

Amagama Omkhiqizo we-Capreomycin

I-Capreomycin itholakala ngaphansi kwegama lomkhiqizo elithi Capastat Sulfate e-United States. Lolu uhlobo oluvame kakhulu olubekwe ngudokotela lomuthi.

Igama elivamile yi-capreomycin sulfate, okuyilokho ozokubona emarekhodini ezokwelapha kanye nemiyalelo kadokotela. Zombili izinhlobo zegama lomkhiqizo kanye nezivamile ziqukethe isithako esifanayo esisebenzayo futhi zisebenza ngendlela efanayo.

Ikhemisi lakho noma umhlinzeki wezempilo angase asebenzise noma yiliphi igama lapho kuxoxwa ngemithi yakho, ngakho-ke kuyasiza ukwazi womabili. Into ebalulekile ukuthi uthola imithi efanele yokwelashwa kwakho kwe-TB.

Ezinye izindlela ze-Capreomycin

Lapho i-capreomycin ingafaneleki noma ingatholakali, udokotela wakho unezinye izindlela eziningi zemithi ye-TB yesibili ongakhetha kuzo. Lezi zindlela zisebenza ngendlela ehlukile kodwa zingasebenza ngokulinganayo ekwelapheni umkhuhlane wamathambo ongamelana nemithi.

I-Amikacin ingenye indlela ejwayelekile esebenza ngendlela efana ne-capreomycin. Njenge-capreomycin, inikezwa njengomjovo futhi ingabangela imiphumela efanayo, ikakhulukazi ethinta ukuzwa kanye nokusebenza kwezinso.

Ezinye izindlela zihlanganisa i-streptomycin, nayo eyi-antibiotic ejovwayo, kanye nemithi ehlukahlukene yomlomo efana ne-fluoroquinolones noma i-ethionamide. Udokotela wakho uzokhetha inhlanganisela engcono kakhulu ngokusekelwe kuphethini yakho ethile yokumelana namagciwane kanye nesimo sempilo.

Ingabe i-Capreomycin Ingcono Kune-Streptomycin?

Kokubili i-capreomycin ne-streptomycin ziyizibulala-magciwane ezijovwayo ezisetshenziselwa i-TB engamelana nemithi, kodwa zomehluko obalulekile. Akukho noyedwa ongcono ngokujwayelekile - ukukhetha kuncike esimweni sakho esithile kanye namagciwane abangela ukutheleleka kwakho.

I-Capreomycin ivame ukukhethwa lapho amagciwane e-TB emelana ne-streptomycin. Ivame ukusebenza kahle ngokumelene nezinhlobo ezimelana ne-streptomycin, okuyenza ibe yindlela ebalulekile ezimeni eziyinkimbinkimbi.

Mayelana nemiphumela emibi, yomibili imithi ingathinta ukuzwa kanye nokusebenza kwezinso, kodwa amaphethini ahlukile kancane. Udokotela wakho uzocabangela umlando wakho wezokwelapha, ukusebenza kwezinso, kanye nesimo sokuzwa lapho ekhetha phakathi kwazo.

Imibuzo Evame Ukubuzwa Mayelana ne-Capreomycin

U-Q1. Ingabe i-Capreomycin iphephile Kwabesifazane Abakhulelwe?

I-Capreomycin ingena esigabeni sokukhulelwa C, okusho ukuthi akukho datha eyanele yomuntu ukunquma ukuphepha ngokucacile. Kodwa-ke, i-TB engelashwanga ibeka izingozi ezinkulu kumama nomntwana.

Udokotela wakho uzohlola ngokucophelela izinzuzo zokwelapha i-TB yakho ngokumelene nezingozi ezingaba khona ekukhulelweni kwakho. Ezimweni eziningi, izinzuzo zokwelapha i-TB esebenzayo zidlula izingozi ezingaba khona zemithi.

Uma ukhulelwe noma uhlela ukukhulelwa, xoxa lokhu ngokucophelela nomhlinzeki wakho wezempilo. Bangase bancomise ukuqapha okwengeziwe noma bacabange ezinye izindlela zokwelapha uma kufanelekile.

U-Q2. Kufanele Ngenzeni Uma Ngiphuthelwa Ngengozi Umthamo We-Capreomycin?

Njengoba i-capreomycin inikezwa ochwepheshe bezempilo, ukuphuthelwa umthamo ngokuvamile kusho ukuphuthelwa i-aphoyintimenti ehleliwe. Xhumana nomhlinzeki wakho wezempilo ngokushesha ukuze uhlele kabusha umjovo wakho.

Ungazami ukuphinda imithamo noma ushintshe uhlelo lwakho ngokwakho. Ukugcina amazinga aqhubekayo omuthi kubalulekile ekwelapheni i-TB ngempumelelo.

Udokotela wakho angase adinge ukulungisa uhlelo lwakho lokwelapha uma uphuthelwa imithamo eminingi, ngakho-ke kubalulekile ukugcina zonke izikhathi zakho ezihleliwe futhi uxhumane nganoma iyiphi inselelo yokuhlela kusenesikhathi.

U-Q3. Kufanele Ngenzeni Uma Ngithola Imiphumela Eceleni?

Bika noma yimiphumela emibi kumhlinzeki wakho wezempilo, ngisho noma ibonakala incane. Ukutholwa kwangaphambi kwesikhathi nokuphathwa kwemiphumela emibi kungavimbela izinkinga ezingathi sína.

Ngemiphumela emibi emincane efana nobuhlungu bendawo yokujova, umhlinzeki wakho angase ancome izinyathelo zokunethezeka. Ngezimpawu ezikhathazayo ezinjengokushintsha kokuzwa noma isiyezi, ungase udinge ukuhlolwa ngokushesha.

Ungayeki ukuthatha i-capreomycin ngaphandle kokubonisana nodokotela wakho kuqala, ngisho noma uthola imiphumela emibi. Ukuyeka ukwelashwa kwe-TB ngaphambi kwesikhathi kungaholela ekwehlulekeni kokwelashwa nasekumelaneni nemithi.

U-Q4. Ngingayeka Nini Ukuthatha I-Capreomycin?

Ungayeka kuphela ukuthatha i-capreomycin uma udokotela wakho enquma ukuthi kuphephile ngokusekelwe emiphumeleni yakho yokuhlolwa nokuphendula kokwelashwa. Lesi sinqumo sidinga ukuhlolwa kwezokwelapha okucophelelayo.

Iqembu lakho lezempilo lizogada amasiko akho e-sputum, ama-X-ray esifuba, nezinye izivivinyo ukuze linqume ukuthi amagciwane e-TB angekho yini. Ukuyeka ngaphambi kwesikhathi kungaholela ekwehlulekeni kokwelashwa.

Noma ngabe uzizwa ungcono ngokuphelele, qhubeka nokwelashwa okuphelele njengoba kunqunywe. Amagciwane e-TB angahlala ohlelweni lwakho ngisho nalapho uzizwa uphilile.

Q5. Uzolugada kanjani udokotela wami ukwelashwa kwami?

Udokotela wakho uzohlela izivivinyo ezivamile zokugada kokubili ukuqhubeka kokwelashwa kwakho nokubheka imiphumela emibi. Lokhu kuvame ukufaka phakathi izivivinyo zokuzwa, umsebenzi wezinso wokuhlola igazi, namasiko e-sputum.

Izivivinyo zokuzwa zisiza ukuthola noma yiziphi izinguquko emandleni akho okulalela kusenesikhathi, ngenkathi ukuhlolwa kwegazi kuhlola ukuthi izinso zakho zisebenza kahle kangakanani imithi. Amasiko e-sputum akhombisa ukuthi amagciwane e-TB ayaphendula yini ekwelashweni.

Ukuvama kwalezi zivivinyo kuyahlukahluka, kodwa lindela ukuqapha kwanyanga zonke ekuqaleni, ngeshejuli engase ilungiswe njengoba ukwelashwa kwakho kuqhubeka. Ukuhlala uqhubeka nalezi zikhathi kubalulekile ekwelashweni okuphephile, okuphumelelayo.