Iyini i-Chloroquine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Chloroquine iyimithi elwa nomalaleveva ebelokhu ivikela abantu kumalaleveva iminyaka engaphezu kwengama-70. Lo muthi oqoshwe ngudokotela usebenza ngokuphazamisa ikhono le-parasite yomalaleveva lokusinda emangqamuzaneni akho abomvu egazi, ngempumelelo imisa ukusabalala kokutheleleka emzimbeni wakho wonke.

Ngenkathi i-chloroquine yayike yaba yindlela yokwelapha umalaleveva emhlabeni wonke, ukusetshenziswa kwayo sekukhethwe kakhulu ngenxa yokukhula kokumelana ezindaweni ezithile. Udokotela wakho uzocabangela ngokucophelela lapho uya khona kanye nomlando wakho wezempilo ngaphambi kokukuyalela lo muthi.

Isetshenziselwani i-Chloroquine?

I-Chloroquine inezinjongo ezimbili ezinkulu emithini yesimanje: ukuvimbela umalaleveva ngaphambi kokuthi uye ezindaweni ezinengozi enkulu nokwelapha izifo eziqhubekayo zomalaleveva. Udokotela wakho uzokuyalela ngokuya ngesimo sakho esithile kanye nengozi yomalaleveva lapho uya khona.

Ukuvimbela umalaleveva, ngokuvamile uzoqala ukuthatha i-chloroquine ngesonto elilodwa kuya kwamabili ngaphambi kokuhamba uye endaweni lapho umalaleveva uvamile. Lokhu kunika umuthi isikhathi sokwakha emzimbeni wakho futhi udale isivikelo esivikela kuma-parasites.

Lapho welapha ukutheleleka komalaleveva okusebenzayo, i-chloroquine ingasusa ngempumelelo ama-parasites egazini lakho. Kodwa-ke, lokhu kusebenza kuphela uma uhlobo lomalaleveva endaweni yakho lungazange luthuthukise ukumelana nomuthi.

Kwezinye izimo, odokotela bangase bayale i-chloroquine ezimweni ezithile ze-autoimmune ezifana ne-rheumatoid arthritis noma i-lupus. Lokhu kwenzeka ngoba umuthi ungasiza ukunciphisa ukuvuvukala emzimbeni wakho, nakuba lokhu kusetshenziswa kungavamile namuhla.

Isebenza Kanjani i-Chloroquine?

I-Chloroquine iqondisa i-parasite yomalaleveva ngesikhathi sesigaba sayo esibuthakathaka lapho ihlala ngaphakathi kwamangqamuzana akho abomvu egazi. Umuthi uphazamisa ikhono le-parasite lokuhlukanisa nokugaya i-hemoglobin, ebalulekile ekusindeni kwayo.

Cabanga ngakho njengokuphazamisa umthombo wokudla we-parasite. Ngaphandle kokukwazi ukucubungula i-hemoglobin ngendlela efanele, i-parasite ye-malaria ngokuyisisekelo ilambela futhi ife ngaphambi kokuthi ikwazi ukuzala futhi isabalale kwamanye amaseli.

Lo muthi ubhekwa njengomuthi oqinile ngokulinganisela futhi osebenza kahle ngokumelene nezinhlobo ze-malaria ezingakazakhi ukumelana. Kodwa-ke, akuyona i-antimalarial enamandla kakhulu etholakalayo, yingakho udokotela wakho engase ancome ezinye izindlela ngokuya ngendawo oya kuyo.

Lo muthi futhi unezindawo ezilwa nokuvuvukala, okuchaza ukuthi kungani ngezinye izikhathi isetshenziselwa izimo ze-autoimmune. Kungasiza ukuthulisa uhlelo lomzimba oluvuvukele oluhlasela izicubu ezinempilo.

Kufanele Ngiyithathe Kanjani I-Chloroquine?

Thatha i-chloroquine ngendlela udokotela wakho ayikushoyo, ngokuvamile ngokudla noma ubisi ukunciphisa isisu esicasulayo. Lo muthi uza ngesimo samaphilisi futhi kufanele ugwinywe wonke nengilazi yamanzi egcwele.

Ukuvimbela i-malaria, ngokuvamile uzothatha umthamo owodwa masonto onke, uqala ngesonto elilodwa kuya kwamabili ngaphambi kohambo lwakho. Qhubeka nokuyithatha masonto onke ngesikhathi sohambo lwakho nangamasonto amane ngemva kokubuya ekhaya, ngisho noma uzizwa ulungile ngokuphelele.

Uma welapha ukutheleleka kwe-malaria okusebenzayo, udokotela wakho cishe uzoqoka umthamo ophezulu ekuqaleni, olandelwa yimithamo emincane ezinsukwini ezimbalwa ezilandelayo. Lolu hlelo lusiza ukunciphisa ngokushesha umthwalo we-parasite ohlelweni lwakho.

Ukuthatha i-chloroquine ngokudla kusiza ukuvimbela isicanucanu nokucasuka kwesisu abanye abantu abakuzwayo. Ukudla okulula noma ukudla okulula kuvame ukwanele, nakuba kufanele ukugweme ukukuthatha esiswini esingenalutho ngokuphelele.

Zama ukuthatha imithamo yakho ngesikhathi esifanayo nsuku zonke ukuze ugcine amazinga aqhubekayo egazini lakho. Ukusetha isikhumbuzi sefoni kungakusiza ukuthi ukhumbule, ikakhulukazi uma uhamba ngamathayimitha.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Chloroquine?

Isikhathi sokwelashwa nge-chloroquine sincike ngokuphelele ekutheni uvimbela umalaleveva noma welapha ukutheleleka okusebenzayo. Udokotela wakho uzonikeza imiyalelo ethile ngokusekelwe esimweni sakho.

Ukuvimbela umalaleveva, uzodinga ukuthatha i-chloroquine ngesikhathi sonke sohambo lwakho kanye namaviki amane engeziwe ngemva kokubuya ekhaya. Lesi sikhathi esandisiwe sibalulekile ngoba izinambuzane zomlaleveva zingahlala zithule esibindini sakho futhi zivele ngemva kwamasonto.

Lapho welapha umalaleveva osebenzayo, inkambo ivame ukuba mfushane kakhulu, ngokuvamile ihlala izinsuku ezintathu kuya kweziyisikhombisa. Udokotela wakho uzoqapha impendulo yakho futhi angase alungise ubude besikhathi ngokusekelwe ekutheni izimpawu zakho zithuthuka ngokushesha kangakanani.

Ungayeki ukuthatha i-chloroquine ngaphambi kwesikhathi, ngisho noma uzizwa ungcono. Izinambuzane zomlaleveva zingaba yinkohliso, futhi ukuyeka ukwelashwa ngokushesha kungase kuzivumele ukuthi ziphindaphinde futhi, okungenzeka kuholele ekuthelelekeni okukhulu.

Yiziphi Izimo Ezingezinhle ze-Chloroquine?

Abantu abaningi bayayibekezelela i-chloroquine kahle, kodwa njenganoma imuphi umuthi, ingabangela imiphumela emibi. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe ulungile futhi wazi ukuthi ungaxhumana nini nodokotela wakho.

Imiphumela emibi evamile abantu abaningi abayizwayo ihlanganisa ukuphazamiseka kwesisu okuncane, isicanucanu, kanye nekhanda. Lezi zimpawu zivame ukuba zesikhashana futhi zivame ukuthuthuka njengoba umzimba wakho ujwayela umuthi.

Nansi imiphumela emibi ebikwa kaningi ongase uyibone:

• Isicanucanu nokungakhululeki kwesisu
• Ikhanda nesiyezi
• Ukulahlekelwa isifiso sokudla
• Ukuqunjelwa okulula
• Ukuqubuka kwesikhumba noma ukuluma
• Umbono ongacacile

Le miphumela emibi evamile ngokuvamile iyazixazulula yona futhi akufanele ikuvimbele ekuqhubekeni nomuthi. Ukuthatha i-chloroquine nokudla kunganciphisa kakhulu izimpawu ezihlobene nesisu.

Imiphumela emibi kakhulu ayivamile kodwa idinga ukunakekelwa kwezempilo ngokushesha. Lokhu kufaka phakathi izinguquko ezinkulu ekuboneni, izinkinga zokuzwa, ubuthakathaka bemisipha, noma izimpawu zezinkinga zesibindi njengokuphuzi kwesikhumba noma amehlo.

Abanye abantu bangase babe nokuguquka kwemizwa, okuhlanganisa ukukhathazeka, ukucasuka, noma amaphupho angajwayelekile. Nakuba le miphumela ngokuvamile ingavamile, kufanelekile ukuxoxa nodokotela wakho uma iba nenkinga.

Ukusetshenziswa kwesikhathi eside kwe-chloroquine ngezinye izikhathi kungathinta i-retina emehlweni akho, yingakho odokotela bencoma ukuhlolwa kwamehlo njalo uma uthatha umuthi isikhathi eside.

Ubani Ongafanele Athole I-Chloroquine?

Abantu abathile kufanele bagweme i-chloroquine ngenxa yengozi eyengeziwe yezinkinga noma ukusebenza kahle okuncishisiwe. Udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokunikeza lo muthi.

Akufanele uthathe i-chloroquine uma wazi ukuthi unokungezwani komzimba nomuthi noma imithi efana ne-hydroxychloroquine. Ukusabela okwedlule kokungezwani komzimba kungahluka kusukela ekuqhumeni kwesikhumba okuncane kuya ekusabeleni okukhulu, okusongela impilo.

Abantu abanezimo ezithile zamehlo, ikakhulukazi izinguquko ze-retinal noma zokubona, kufanele bagweme i-chloroquine. Umuthi ungenza lezi zimo zibe zimbi futhi ungase ulimaze ukubona unomphela.

Uma une-psoriasis, i-chloroquine ingase ibangele ukuqubuka kwesimo sakho sesikhumba. Udokotela wakho uzohlola izinzuzo ngokumelene nezingozi futhi angase ancome imithi ehlukile ye-antimalarial.

Abantu abanezifo ezinzima zesibindi noma izinso kungenzeka bangakwazi ukucubungula i-chloroquine ngendlela efanele, okuholela ekunqwabelaneni okuyingozi komuthi ohlelweni lwabo. Udokotela wakho uzohlola ukusebenza kwezitho zakho ngaphambi kokuyinikeza.

Abesifazane abakhulelwe kufanele basebenzise i-chloroquine kuphela uma izinzuzo zicacile ukwedlula izingozi. Nakuba ngokuvamile ithathwa njengephephile kunezinye izindlela ngesikhathi sokukhulelwa, udokotela wakho uzohlola ngokucophelela isimo sakho esithile.

Abantu abanezinkinga zokushaya kwenhliziyo noma labo abathatha imithi ethinta ukushaya kwenhliziyo kufanele basebenzise i-chloroquine ngokucophelela okukhulu, njengoba ingase iqhubekisele phambili lezi zimo.

Amagama e-Brand ye-Chloroquine

I-Chloroquine itholakala ngaphansi kwamagama amaningi e-brand, nakuba inguqulo ejwayelekile ivame ukunqunywa. E-United States, ungahlangana nayo njenge-Aralen, okuyigama le-brand elaziwa kakhulu.

Ezinye izindawo zingase zibe namagama e-brand ahlukene e-chloroquine, ngakho kubalulekile ukuqonda ukuthi isithako esisebenzayo sihlala sifana kungakhathaliseki umenzi. Umkhemisi wakho angasiza ukucacisa uma uhamba phesheya.

I-Chloroquine ejwayelekile isebenza kahle njengezinguqulo zegama le-brand futhi ivame ukuthengeka. Isithako esisebenzayo kanye nokulinganisa kufana, ngakho ungakhathazeki uma ikhemisi lakho linikeza inguqulo ejwayelekile.

Ezinye izindlela ze-Chloroquine

Imithi eminingi ehlukile iyatholakala uma i-chloroquine ingakulungele noma uma uhamba endaweni enomdlavuza we-chloroquine-resistant. Udokotela wakho uzokhetha inketho engcono kakhulu ngokusekelwe lapho uya khona kanye nephrofayili yakho yezempilo.

I-Doxycycline iyindlela ethandwayo esebenza kahle ngokumelene nezinhlobo zomdlavuza we-chloroquine-resistant. Ithathwa nsuku zonke kunokuba masonto onke futhi inemiphumela ehlukene, okuhlanganisa ukwanda kokuzwela elangeni.

I-Mefloquine (Lariam) ngomunye umuthi wamasonto onke osebenza ezindaweni lapho ukumelana ne-chloroquine kuvamile. Kodwa-ke, ingabangela imiphumela ye-neuropsychiatric kwabanye abantu, okuhlanganisa amaphupho acacile kanye nezinguquko zemizwa.

I-Atovaquone-proguanil (Malarone) ivame ukukhethwa ohambweni olufushane ngoba udinga ukuyithatha isonto elilodwa kuphela ngemva kokubuya ekhaya. Ngokuvamile iyabekezeleleka kodwa ibiza kakhulu kunezinye izinketho.

Ukwelapha umalaleveva okhona, ukwelashwa okuhlanganisa i-artemisinin manje kuyindlela engcono kakhulu ezingxenyeni eziningi zomhlaba. Le mithi isebenza ngokushesha kune-chloroquine futhi isebenza kahle ezinhlotsheni ezingamelani.

Ingabe i-Chloroquine Ingcono Kune-Doxycycline?

Noma i-chloroquine noma i-doxycycline ayikho "ngcono" ngokujwayelekile - ukukhetha kuncike esimweni sakho esithile, lapho ohamba khona, kanye nezinto ezithinta impilo yakho. Umuthi ngamunye unezinzuzo ezihlukile kanye nezinto okufanele zicatshangelwe.

I-Chloroquine inikeza lula lokuthatha umthamo kanye ngesonto futhi isetshenziswe ngokuphepha amashumi eminyaka. Ivame ukukhethwa ezindaweni lapho ukumelana nomalaleveva kungakhathazi, futhi ngokuvamile iphephile ezinganeni nakwabesifazane abakhulelwe uma kudingeka.

I-Doxycycline idinga ukuthatha umthamo nsuku zonke kodwa isebenza kahle ezinhlotsheni zomlaleveva ezingamelani ne-chloroquine. Ivame ukukhethwa uma uhambela eNingizimu-mpumalanga ye-Asia, izingxenye ze-Afrika, kanye neNingizimu Melika lapho ukumelana kuvamile.

Umehluko wezimpawu ezingezinhle uhluke kakhulu phakathi kwale mithi. I-Chloroquine ingase ibangele ukuqunjelwa kwesisu futhi, ngezinye izikhathi, izinguquko embonweni uma isetshenziswa isikhathi eside. I-Doxycycline ingakhuphula ukuzwela elangeni futhi ngezinye izikhathi ibangela ukucasuka kwe-esophageal.

Udokotela wakho uzocabangela izinto ezinjengamaphethini okumelana nendawo oya kuyo, ubude bohambo lwakho, umlando wakho wezokwelapha, kanye nezintandokazi zakho lapho ekhetha phakathi kwale mithi.

Imibuzo Evame Ukubuzwa Mayelana ne-Chloroquine

Ingabe i-Chloroquine iphephile ku-Diabetes?

I-Chloroquine ingasetshenziswa ngokuphepha ngabantu abaningi abanesifo sikashukela, kodwa idinga ukuqapha ngokucophelela. Umuthi ngezinye izikhathi ungathinta amazinga kashukela egazini, okungenzeka ukuthi abangele ukuthi ehlise ngaphansi kokujwayelekile.

Uma unesifo sikashukela, udokotela wakho cishe uzoncoma ukuhlola ushukela wakho wegazi kaningi lapho uqala i-chloroquine. Lokhu kusiza ukuqinisekisa ukuthi amazinga akho ahlala ezinzile futhi kuvumela ukulungiswa kwemithi uma kudingeka.

Abantu abathatha i-insulin noma eminye imithi yesifo sikashukela kufanele baqaphele kakhulu ukuqapha ushukela wabo wegazi. Ukusebenzisana phakathi kwe-chloroquine nemithi yesifo sikashukela ngezinye izikhathi kungathuthukisa imiphumela yokwehlisa ushukela wegazi.

Kufanele ngenzeni uma ngiphuzile i-Chloroquine eningi ngengozi?

Uma ngengozi uphuze i-chloroquine eningi, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukweqisa kwe-Chloroquine kungaba kubi futhi kudinga ukunakekelwa kwezokwelapha okusheshayo.

Izimpawu zokweqisa kwe-chloroquine zihlanganisa isicanucanu esibi, ukuhlanza, ukozela, izinguquko zombono, nezinkinga zesigqi senhliziyo. Ungalindi ukuthi izimpawu zivele - funa usizo ngokushesha uma uthathe okungaphezu kokunqunyiwe.

Ngenkathi ulinde usizo lwezokwelapha, ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngqo ngumhlinzeki wezempilo. Gcina ibhodlela lemithi nawe ukuze ochwepheshe bezokwelapha bakwazi ukubona kahle ukuthi uthatheni ini nokuthi ungakanani.

Kufanele ngenzeni uma ngiphuthelwa umthamo we-Chloroquine?

Uma uphuthelwa umthamo we-chloroquine wamasonto onke wokuvimbela umalaleveva, uyithathe ngokushesha lapho ukhumbula. Uma sekuyisikhathi somthamo wakho olandelayo, weqa umthamo ophuthelwe futhi uqhubeke neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungakhuphula ingozi yakho yemiphumela engemihle ngaphandle kokuhlinzeka ngokuvikelwa okwengeziwe kumalaleveva.

Ukuze uthole imithamo yokwelapha, xhumana nodokotela wakho ukuze uthole isiqondiso semithamo ephuthelwe. Isikhathi sokwelashwa komalaleveva sibalulekile, futhi udokotela wakho kungadingeka ukuthi alungise ishejuli yakho ngokusekelwe ekutheni uphuthelwe nini umthamo.

Ngingayeka nini ukuthatha i-Chloroquine?

Ukuvimbela umalaleveva, kufanele uqhubeke nokuthatha i-chloroquine amasonto amane ngemva kokushiya indawo enomalaleveva. Lokhu kubalulekile ngoba amapharasayithi omalaleveva angahlala ethule esibindini sakho futhi avele kamuva.

Uma welapha umalaleveva oqhubekayo, yeka kuphela ukuthatha i-chloroquine uma udokotela wakho ekutshela ukuthi wenze njalo. Noma ngabe uzizwa ungcono ngokuphelele, ukuyeka ngaphambi kwesikhathi kungavumela ukuthi ukutheleleka kubuye futhi kube kubi kakhulu.

Uma uhlangabezana nemiphumela engathandeki, xhumana nodokotela wakho kunokuyeka imithi ngokwakho. Bangakwazi ukusiza ekuphatheni imiphumela emibi noma bakushintshele kwenye imithi uma kudingeka.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Chloroquine?

Ngenkathi kungekho ukuxhumana okuqondile okuyingozi phakathi kwe-chloroquine notshwala, kungcono ukukhawulela ukusetshenziswa kotshwala ngenkathi uthatha le mithi. Utshwala bungakwenza kube kubi eminye yemiphumela emibi ye-chloroquine, ikakhulukazi ukuphazamiseka kwesisu kanye nesiyezi.

Uma uthatha i-chloroquine ukuvimbela umalaleveva ngenkathi uhamba, khumbula ukuthi utshwala bungaphazamisa ukwahlulela kwakho futhi kukwenze ukhohlwe imithamo noma unganaki ezinye izinyathelo zokuzivikela njengokusebenzisa isinambuzane.

Ukusetshenziswa kotshwala ngokweqile kungathinta amasosha akho omzimba, okungenzeka kukwenze ukuthi uthatheke kalula ezifweni. Ukulinganisela kubalulekile, ikakhulukazi uma usendaweni lapho umalaleveva eyingozi khona.