Yini i-Cromolyn (Indlela Yomlomo): Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

Umuthi womlomo we-Cromolyn ungumuthi olula olwa nokuvuvukala osiza ukuvimbela ukusabela komzimba emzimbeni wakho wokugaya ukudla. Usebenza ngokuzinzisa amaseli athile omzimba okuthiwa ama-mast cells, akhulula amakhemikhali abangela izimpawu zokungezwani komzimba uma udla ukudla umzimba wakho ongenakukubekezelela.

Lo muthi ulusizo ikakhulukazi kubantu abanezifo zokungezwani komzimba nokudla noma isimo esibizwa ngokuthi i-mastocytosis, lapho umzimba wakho ukhiqiza amaseli e-mast amaningi kakhulu. Ngokungafani nemithi eqinile yokungezwani komzimba, i-cromolyn ithathwa njengemnene kakhulu futhi iphephile ukusetshenziswa isikhathi eside, okuyenza ibe yindlela ekhethwayo yokuphatha izifo zokungezwani komzimba eziqhubekayo.

Yini i-Cromolyn Esetshenziselwa Yona?

Umuthi womlomo we-Cromolyn ngokuyinhloko welapha i-mastocytosis, isimo lapho umzimba wakho udala amaseli e-mast amaningi kakhulu angabangela ukusabela komzimba okungakhululeki. Isiza ukunciphisa izimpawu ezinjengobuhlungu besisu, isifo sohudo, isicanucanu, nokubomvu kwesikhumba okwenzeka lapho la maseli ekhulula amakhemikhali amaningi kakhulu okuvuvukala.

Udokotela wakho angase futhi anqume i-cromolyn ngezifo zokungezwani komzimba nokudla, ikakhulukazi uma uhlangabezana nezimpawu zokugaya ukudla ngemva kokudla ukudla okuthile. Umuthi usebenza njengokwelashwa kokuvimbela, okusho ukuthi usiza ukumisa ukusabela komzimba ngaphambi kokuba kuqale kunokuba kuwelaphe ngemva kokuba kwenzekile.

Abanye odokotela basebenzisa i-cromolyn ngaphandle kwetheyibuli kwezinye izimo ezinjengezimpawu zamathumbu avuvukalayo noma izinhlobo ezithile zesifo sohudo esingamahlalakhona. Nokho, lokhu kusetshenziswa akuvamile futhi kufanele kucatshangelwe kuphela ngaphansi kokuqondiswa kwezokwelapha okucophelelayo.

Isebenza Kanjani i-Cromolyn?

I-Cromolyn isebenza ngokuzinzisa amaseli e-mast ohlelweni lwakho lokugaya ukudla, iwawavimbela ukuthi angakhululi amakhemikhali okuvuvukala njenge-histamine. Cabanga ngamaseli e-mast njengamasistimu e-alamu amancane angase avuleke kalula uma udla ukudla okuthile noma uma unawo amaningi emzimbeni wakho.

Lo muthi uthathwa njengokwelashwa okulula, okunobumnene uma kuqhathaniswa nemithi eqeda ukuvuvukala enamandla efana nama-steroid. Awucindezeli lonke uhlelo lwakho lomzimba lokuzivikela kodwa uqondise ngqo amaseli abangela ukungezwani komzimba emathunjini akho.

Umuthi uthatha isikhathi ukwakheka emzimbeni wakho bese uqala ukusebenza ngempumelelo. Ngokuvamile ngeke uzizwe ukhululekile ngokushesha njengoba ungase uzizwe ngama-antihistamine, kodwa emavikini amaningana, kufanele uqaphele izimpawu ezimbalwa nezincane zokungezwani komzimba.

Ngingawuthatha Kanjani U-Cromolyn?

Thatha i-cromolyn ngendlela udokotela wakho ayala ngayo, ngokuvamile imizuzu engama-30 ngaphambi kokudla nangaphambi kokulala. Umuthi uza njengempushana oyixuba namanzi ukuze udale isixazululo ongakwazi ukusiphuza.

Xuba umthamo ngamunye nengxenye yengilazi yamanzi bese uwaphuza ngokushesha ngemva kokuxuba. Ungalungisi imithamo kusengaphambili, njengoba umuthi usebenza kangcono uma usanda kuxutshwa. Ungawuthatha nokudla noma ngaphandle kokudla, kodwa ukuwuthatha ngaphambi kokudla kuvame ukusiza ekungezwaneni komzimba okuhlobene nokudla.

Uma uthola ukuthi ukunambitheka akumnandi, ungaxuba impushana nenani elincane lejusi lezithelo esikhundleni samanzi. Nokho, gwema iziphuzo ezishisayo njengoba ukushisa kunganciphisa ukusebenza komuthi.

Gcina impushana ekamelweni lokushisa endaweni eyomile, futhi uyigcine kude nomswakama nelanga eliqondile. Ungayifaki impushana esiqandisini, kodwa ungaqandisa isixazululo esixutshiwe uma ukuthanda kubanda.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Cromolyn?

Abantu abaningi badinga ukuthatha i-cromolyn okungenani amasonto ama-2 kuya kwama-3 ngaphambi kokubona ukuthuthuka okukhulu ezimpawini zabo. Umuthi wakheka kancane kancane emzimbeni wakho, ngakho ukubekezela kubalulekile emasontweni ambalwa okuqala okwelashwa.

Nge-mastocytosis, cishe uzodinga ukuthatha i-cromolyn isikhathi eside, mhlawumbe izinyanga noma iminyaka, kuye ngobukhulu besimo sakho. Udokotela wakho uzoqapha inqubekela phambili yakho futhi alungise uhlelo lokwelashwa njengoba kudingeka.

Uma usebenzisa i-cromolyn ngenxa yokungezwani nokudla, ubude besikhathi sincike ekutheni uyakugwema yini ukudla okubangela izinkinga noma usebenzela ukubekezelela. Abanye abantu bayayithatha okwesikhashana ngenkathi bethola ukudla okubangela izinkinga, kanti abanye bayayisebenzisa njengokuvikela okuqhubekayo.

Ungayeki ukuthatha i-cromolyn ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Izimpawu zakho zingase zibuye, futhi kuvame ukuba ngcono ukunciphisa umthamo kancane kancane kunokuyeka ngokuphazima kweso.

Yiziphi Imiphumela Eceleni ye-Cromolyn?

I-Cromolyn ivame ukubekezelelwa kahle, futhi abantu abaningi abanayo imiphumela eminingi eceleni. Uma imiphumela emibi yenzeka, ivame ukuba mnene futhi yesikhashana njengoba umzimba wakho ujwayela umuthi.

Nawa amanye imiphumela emibi ejwayelekile ongase uyithole emasontweni ambalwa okuqala kokwelashwa:

• Ukuphazamiseka kwesisu noma isicanucanu esincane
• Ikhanda
• Isiyezi
• Ukuqubuka kwesikhumba noma ukuluma
• Ubuhlungu emalungeni noma emisipheni
• Ukuphuma isifo sohudo noma izinguquko ekuhambeni kwamathumbu

Lezi zimpawu ngokuvamile ziyathuthuka njengoba umzimba wakho ujwayela umuthi. Uma ziqhubeka noma ziba zimbi ngemva kwamasonto ambalwa, xhumana nodokotela wakho ukuze uthole isiqondiso.

Imiphumela emibi engavamile kodwa ebucayi ingabandakanya ukusabela okukhulu komzimba, ubunzima bokugwinya, noma ubuhlungu besisu obuqhubekayo. Nakuba lokhu kungavamile, kudinga ukunakekelwa kwezempilo ngokushesha uma kwenzeka.

Abanye abantu bangase babe nezinguquko zemizwa noma ubunzima bokulala, nakuba lokhu kungavamile nge-cromolyn yomlomo uma kuqhathaniswa nezinye izinhlobo zomuthi.

Ubani Ongafanele Athole i-Cromolyn?

Akufanele uthathe i-cromolyn uma unokungezwani ne-cromolyn sodium noma yiziphi izithako emuthini. Abantu abanezifo ezinzima zezinso noma isibindi bangase badinge ukulungiswa komthamo noma ukwelashwa okuhlukile.

Abesifazane abakhulelwe nabancelisayo kufanele baxoxe ngokusebenzisa i-cromolyn nodokotela babo, nakuba imithi ngokuvamile ithathwa njengephephile ngesikhathi sokukhulelwa uma izinzuzo zidlula izingozi. Imithi idlulela obisini ngamanani amancane, kodwa imiphumela emibi ezinganeni ezincelisayo ayivamile.

Izingane zingayithatha ngokuphepha i-cromolyn, kodwa ukulinganisa umthamo kudingeka kubalwe ngokucophelela ngokuya ngesisindo sabo nobudala. Udokotela wezingane zakho uzonquma umthamo ofanele wengane yakho.

Uma unomlando wokungezwani okukhulu nemithi, yazisa udokotela wakho ngaphambi kokuqala i-cromolyn. Nakuba kungavamile, abanye abantu bangase babe nokungezwani okusha nemithi ngisho noma bengakaze babe nezinkinga ngaphambili.

Amagama Omkhiqizo we-Cromolyn

Igama elivamile lomkhiqizo we-cromolyn ngomlomo yi-Gastrocrom, etholakala kabanzi e-United States. Lo mkhiqizo uza njengamaphakethe ngamanye e-powder oyixuba namanzi ngaphambi kokuyithatha.

Amanye amakhemisi okuhlanganisa angase alungise i-cromolyn ngezindlela ezihlukene noma ukugxila uma udokotela wakho ebeka umthamo owenziwe ngendlela oyifisayo. Izinhlobo ezivamile ze-cromolyn sodium nazo ziyatholakala futhi zisebenza ngempumelelo njengezinhlobo zegama lomkhiqizo.

Njalo hlola nomkhemisi wakho uma unemibuzo mayelana nemikhiqizo ehlukene noma izindlela zokulungiselela. Bangasiza ekuqinisekiseni ukuthi uthola imithi efanele ngamandla afanele.

Ezinye Izindlela ze-Cromolyn

Uma i-cromolyn ingasebenzi kahle kuwe noma ibangela imiphumela engathandeki, udokotela wakho angase acabange ezinye izinto ezizinzisa amaseli e-mast njenge-ketotifen, nakuba lokhu kungasetshenziswa kakhulu ngezimpawu zokugaya ukudla.

Nge-mastocytosis, ezinye izindlela zingabandakanya ama-antihistamines afana ne-loratadine noma i-cetirizine, ikakhulukazi ekulawuleni ukulunywa nezimpawu zesikhumba. Abanye abantu bayazuza ekuhlanganiseni i-cromolyn nama-antihistamines ukuze kulawulwe kangcono izimpawu.

Ezokungezwani kokudla, ukugwema ngokuqinile ukudla okubangela izimpawu kusengumkhuba osebenzayo kakhulu. Udokotela wakho angase futhi ancome ama-antihistamine ukuze uwathathe ngaphambi kokudla uma ngengozi udla ukudla okuyinkinga.

Ezimweni ezinzima, udokotela wakho angase anqume imithi eqinile efana ne-omalizumab (umuthi ojovwayo) noma i-aspirin enomthamo ophansi, nakuba lokhu kuza nemiphumela eminingi engaba khona futhi kudinga ukuqapha okuseduze.

Ingabe i-Cromolyn Ingcono Kune-Antihistamines?

I-Cromolyn nama-antihistamine asebenza ngendlela ehlukile, ngakho ukuwaqhathanisa ngokuqondile akulula. I-Cromolyn ivimbela amaseli e-mast ukuthi angakhiphi amakhemikhali avuvukalisayo, kuyilapho ama-antihistamine evimba imiphumela ye-histamine ngemva kokuthi isivele ikhishwe.

Ukuvimbela izimpawu zokungezwani kokudla, i-cromolyn ivame ukusebenza kahle ngoba imisa ukusabela emthonjeni wayo. Ama-Antihistamine asebenza ngokushesha ukuze athole ukukhululeka ngokushesha kodwa awavimbeli inqubo evuvukalisayo engaphansi.

Abantu abaningi bathola ukuthi ukuhlanganisa yomibili imithi kubanika ukulawula okungcono kakhulu kwezimpawu. I-Cromolyn inikeza ukuvikelwa okuyisisekelo, kuyilapho ama-antihistamine enikeza ukukhululeka okuyisipele ezimpawini eziphuma ngaphandle.

Ukukhetha phakathi kwazo kuncike esimweni sakho esithile, amaphethini ezimpawu, nokuthi ukubekezelela kahle kangakanani umuthi ngamunye. Udokotela wakho uzosiza ekunqumeni indlela engcono kakhulu yesimo sakho.

Imibuzo Evame Ukubuzwa Mayelana ne-Cromolyn

Ingabe i-Cromolyn Iphephile Ukusetshenziswa Isikhathi Eside?

Yebo, i-cromolyn ithathwa njengephephile kakhulu ukusetshenziswa isikhathi eside, ngisho nezinyanga noma iminyaka. Ngokungafani nama-steroid noma eminye imithi eqinile elwa nokuvuvukala, i-cromolyn ayicindezeli amasosha akho omzimba noma ibangele imiphumela emibi yesikhathi eside.

Udokotela wakho usazofuna ukuqapha intuthuko yakho njalo, kodwa abantu abaningi bangathatha i-cromolyn ngokuphepha isikhathi eside ngaphandle kwezingozi ezinkulu zempilo.

Ngingenzani Uma Ngengozi Ngithatha I-Cromolyn Eningi Kakhulu?

Uma ngabe uthatha i-cromolyn eningi kunaleyo oyinikiwe, ungesabi. Ukweqisa imithamo akuvamile futhi kuvame ukubangela izimpawu ezilula kuphela njengokungakhululeki kwesisu noma isicanucanu.

Phuza amanzi amaningi futhi uthintane nodokotela wakho noma usokhemisi ukuze uthole isiqondiso. Uma uhlangabezana nezimpawu ezinzima njengobunzima bokuphefumula, isiyezi, noma ukuhlanza okuqhubekayo, funa usizo lwezokwelapha ngokushesha.

Kufanele Ngenzeni Uma Ngeqa Umthamo We-Cromolyn?

Uma uqa umthamo, wuthatha ngokushesha nje lapho ukhumbula, ngaphandle uma sekuseduze isikhathi somthamo wakho olandelayo. Ungaphindi imithamo ukuze ulungise lowo oqediwe.

Uma uvame ukukhohlwa imithamo, zama ukusetha izikhumbuzi zocingo noma uthathe imithi yakho ngezikhathi ezifanayo nsuku zonke. Ukuthatha imithi ngokuqhubekayo kusiza ukugcina amazinga aqinile ohlelweni lwakho ukuze kulawulwe kangcono izimpawu.

Ngingayeka Nini Ukuthatha I-Cromolyn?

Yeka kuphela ukuthatha i-cromolyn ngemva kokuxoxa ngayo nodokotela wakho kuqala. Isikhathi sincike esimweni sakho nokuthi usabela kahle kangakanani ekwelashweni.

Ngokwe-mastocytosis, ungase udinge ukwelashwa kwesikhathi eside. Ngokungezwani nokudla, ungase ukwazi ukuyeka uma usuveze futhi waqeda ukudla okubangela izimpawu noma uma izimpawu zakho zikwazi ukulawulwa kahle isikhathi eside.

Ngingayithatha I-Cromolyn Ngeminye Imithi?

I-Cromolyn inokuxhumana okumbalwa kakhulu kwemithi, okuyenza iphephe ukuyithatha neminye imithi eminingi. Nokho, ngaso sonke isikhathi yazisa udokotela wakho nosokhemisi ngayo yonke imithi, izithasiselo, kanye nemikhiqizo yamakhambi oyithathayo.

Abanye abantu bathatha i-cromolyn kanye nama-antihistamine, ama-proton pump inhibitors, noma eminye imithi yokungezwani ngaphandle kwezinkinga. Ithimba lakho lezempilo lingasiza ekuqinisekiseni ukuthi yonke imithi yakho isebenza kahle ndawonye.