Dacomitinib (indaba yokumunca)
Imikhiqizo etholakalayo
Vizimpro
Mayelana naleli khambi
Dacomitinib isetshenziswa ekwelapheni umdlavuza wekhanda elingenawo amaseli amancane osekusile (osekuyelele) onomfutho we-epidermal growth factor receptor (EGFR) exon 19 deletion noma exon 21L858Rsubstitution mutation gene. Udokotela wakho uzosebenzisa ukuhlolwa ukuhlola ukuguqulwa kwesakhiwo ngaphambi kokuthi uthole le mishini. Le mishini itholakala kuphela ngomyalo wodokotela. Lo mkhiqizo utholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Uma ukhetha ukusebenzisa le mishini, kufanele kuqhathaniswe ingozi yokusebenzisa le mishini nezinzuzo ezizoletha. Lo ngumqondo owenzayo wena nodokotela wakho. Ngale mishini, kufanele kucabangelwe okulandelayo: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo olukhulu noma oluhambelanayo lokuphazamiseka kule mishini noma kwezinye izidakamizwa. Tshela odokotela wakho uma unanoma yiluphi olunye uhlobo lokuphazamiseka, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenayo iresiphi, funda ilebula noma izithako zephakheji ngokucophelela. Akwenziwanga ucwaningo olufanele mayelana nobudlelwano bobudala nemiphumela ka-dacomitinib kubantwana. Ukuphepha nokuphumelela akukaqiniswanga. Ucwaningo olufanele oluqediwe kuze kube manje alubonisi izinkinga ezikhethekile zabantu abadala ezingalimi ukusetshenziswa kwe-dacomitinib kubantu abadala. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mishini ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokusebenzisa le mishini ngesikhathi sokuncelisa. Nakuba ezinye izidakamizwa kufanele zingasetshenziswa ndawonye, kwezinye izimo izidakamizwa ezimbili ezahlukene zingasetshenziswa ndawonye ngisho noma kungenzeka ukuthi kube khona ukusebenzisana. Kulezi zimo, udokotela wakho angase afune ukushintsha umthamo, noma ezinye izinyathelo zokuphepha kungase kudingeke. Uma uthatha le mishini, kubalulekile ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma yiziphi izidakamizwa ezibalwe ngezansi. Ukusebenzisana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mishini nanoma yiziphi izidakamizwa ezilandelayo ngokuvamile akunconywa, kodwa kungase kudingeke kwezinye izimo. Uma kokubili izidakamizwa ziyalelwe ndawonye, udokotela wakho angase ashintshe umthamo noma ukuthi ulisebenzisa kangakanani olunye noma kokubili izidakamizwa. Ezinye izidakamizwa akufanele zisetshenziswe ngesikhathi sokudla noma eduze kwesikhathi sokudla noma ukudla izinhlobo ezithile zokudla ngoba ukusebenzisana kungase kwenzeke. Ukusebenzisa utshwala noma utshaba nezinye izidakamizwa kungase futhi kubangele ukusebenzisana. Xoxa nochwepheshe bakho bezempilo ngokusetshenziswa kwemishini yakho ngokudla, utshwala, noma utshaba. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mishini. Qiniseka ukuthi utshela udokotela wakho uma unanoma yiziphi ezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza ngokuqondile njengoba kunqunyiwe udokotela wakho. Ungathathi okuningi kwalokhu, ungalithathi kaningi, futhi ungalithathi isikhathi eside kunalokho udokotela wakho akuyalile. Leli leyeza liza ne-insert yolwazi lwabaguli. Funda bese ulandela imiyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Ungathatha leli leyeza ngokudla noma ngaphandle kokudla. Thatha leli leyeza okungenani amahora angu-6 ngaphambi noma amahora angu-10 ngemuva kokusebenzisa i-antacid noma i-H2 blocker (eg, cimetidine, ranitidine). Inani leli leyeza lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi aleli leyeza. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani leyeza olithathayo lixhomeke emandleni leyeza. Futhi, inani lezinani olithathayo nsuku zonke, isikhathi esivunyelwe phakathi kwezinani, nobude besikhathi olithatha leyeza kuya ngenkinga yezokwelapha oyisebenzisela leli leyeza. Uma uphuthelwe inani leli leyeza, suka kulelo nani eliphuthelwe bese ubuyela esimweni sakho sokuthola inani. Ungawandisi amanani. Uma uphuka ngemuva kokuthatha inani, thatha inani elilandelayo ngesikhathi esivamile. Gcina leli leyeza esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okuqondile. Gcina ungaganduki. Gcina ungafinyeleleki ezinganeni. Ungagcini leyeza eliphelile noma leyeza elingasasetshenziswa. Buza ochwepheshe bakho bezempilo ukuthi kufanele ulahle kanjani noma yiliphi leyeza ongeke ulisetshenzise.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.