Dapagliflozin nemetformin (indlela yokwelapha ngomlomo)
Imikhiqizo etholakalayo
Xigduo XR
Mayelana naleli khambi
Ukusetshenziswa kweDapagliflozin neMetformin kuhlanganiswe nokudla okulungile nokuzivocavoca ukuze kuphathwe isifo sikashukela sohlobo 2. Kusetshenziswa futhi ukunciphisa ingozi yokungeniswa esibhedlela ngenxa yokwehluleka kwenhliziyo kubantu abanesifo sikashukela sohlobo 2 nesifo senhliziyo (inhliziyo noma imithambo yegazi) noma izici eziningi ezingozi yempilo yomuthambo. Lolukhuni luphinde lusetshenziswe ukunciphisa ingozi yokufa komuthambo wegazi nokungeniswa esibhedlela kubantu abanehluleko lenhliziyo eline-ejection fraction ephansi (inhliziyo ibuthakathaka futhi ayikwazi ukupompa igazi elanele emzimbeni wonke). Ukusetshenziswa kweDapagliflozin neMetformin kuphinde kusetshenziswe ukunciphisa ingozi yokuba sibi kwezifo zokwephula, isifo sokwehluleka kwesigxobo, ukufa komuthambo wegazi, nokungeniswa esibhedlela ngenxa yokwehluleka kwenhliziyo kubantu abanesifo sokwehluleka kwesigxobo. I-Dapagliflozin isebenza ezinso ukuvimbela ukufunwa kwe-glucose (ishukela legazi). Lokhu kusiza ekuphuculeni amazinga eshukela legazi. I-Metformin iyancipha ukufunwa kweshukela esiswini, iyancipha ukukhishwa kweshukela elihlanganisiwe e-liver, futhi ikusiza umzimba wakho ukusebenzisa ishukela kangcono. Ayincedi abantu abanesifo sikashukela esixhomekeke kwi-insulin noma uhlobo 1. Abantu abanesifo sikashukela sohlobo 1 kufanele basebenzise ukugxilwa kwe-insulin. Lolukhuni luyatholakala kuphela ngomyalo wezokwelapha. Lo mkhiqizo uyatholakala ngezindlela zokulinganisa ezilandelayo:
Ngaphambi kokusebenzisa leli khambi
Ekubeni kunqunywe ukusebenzisa imithi, izingozi zokuthatha imithi kufanele ziqhathaniswe nezinzuzo ezizokwenzeka. Lo ngumqondo owenzayo wena nodokotela wakho. Kulo muthi, okulandelayo kufanele kucabangelwe: Tshela udokotela wakho uma uke waba nanoma yiluphi uhlobo oluqondile noma oluqondile lokuphazamiseka kwale mithi noma eminye imithi. Tshela futhi ochwepheshe bakho bezempilo uma unezinye izinhlobo zokuphazamiseka, njengokudla, izidakamizwa, izigcini, noma izilwane. Ngomkhiqizo ongenamithi, funda ilebula noma izithako zephakheji ngokucophelela. Izifundo ezifanele azikwenzelwanga ubudlelwano bobudala nemiphumela yokudibanisa i-dapagliflozin ne-metformin kubantwana abaneminyaka engaphansi kwengu-10 ukuze baphathwe isifo sikashukela sohlobo 2 nakubantwana ukuze baphathwe ezinye izimo. Ukuphepha nokuphumelela akukaqiniswa. Izifundo ezifanele ezenziwe kuze kube manje azibonisi izinkinga ezikhethekile zabantu abadala ezingalinda ukusetshenziswa kokudibanisa i-dapagliflozin ne-metformin kubantu abadala. Noma kunjalo, abantu abadala banesikhathi esiningi sokuhlupheka ngezinkinga zezinkalankala, isibindi, noma inhliziyo, okungadinga ukuqapha nokulungiswa komthamo kubantu abamukela ukuxuba kwe-dapagliflozin ne-metformin. Ayikho izifundo ezifanele kubesifazane zokunquma ingozi yengane uma usebenzisa le mithi ngesikhathi sokuncelisa. Linganisa izinzuzo ezingaba khona nezingozi ezingaba khona ngaphambi kokuthatha le mithi ngesikhathi sokuncelisa. Nakuba imithi ethile ingafanele isetshenziswe ndawonye nhlobo, kwezinye izimo imithi emibili ehlukene ingasetshenziswa ndawonye ngisho noma kungenzeka ukuhlangana. Kulezi zimo, udokotela wakho angafuna ukushintsha umthamo, noma ezinye izinyathelo zokuphepha zingadingeka. Uma uthatha le mithi, kubalulekile kakhulu ukuthi ochwepheshe bakho bezempilo bazi uma uthatha noma yimiphi imithi ehlongozwayo ngezansi. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo ngokuvamile akusikholisi, kodwa kungadingeka kwezinye izimo. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Ukusebenzisa le mithi nanoma yimiphi imithi elandelayo kungabangela ukwanda kengozi yezinye izingozi ezibekiwe, kodwa ukusebenzisa kokubili imithi kungaba ukwelashwa okuhle kuwe. Uma kokubili imithi ilotshiwe ndawonye, udokotela wakho angashintsha umthamo noma ukuthi uyayisebenzisa kangakanani enye noma kokubili imithi. Imithi ethile akufanele isetshenziswe ngesikhathi noma eduze kwesikhathi sokudla ukudla noma ukudla izinhlobo ezithile zokudla njengoba kungenzeka ukuhlangana. Ukusebenzisa utshwala noma utshaba nanoma yimiphi imithi kungabangela futhi ukuhlangana. Ukuhlangana okulandelayo kukhethwe ngokusekelwe ekubalulekeni kwabo okungenzeka futhi akuyona yonke into. Ukuba khona kwezinye izinkinga zezokwelapha kungathinta ukusetshenziswa kwale mithi. Qiniseka ukuthi utshela udokotela wakho uma unezinye izinkinga zezokwelapha, ikakhulukazi:
Indlela yokusebenzisa leli khambi
Thatha leli leyeza kuphela njengoba kunqunyiwe ngudokotela wakho. Ungalisebenzisi kakhulu, ungalisebenzisi njalo, futhi ungalisebenzisi isikhathi eside kunalokho okunqunyiwe ngudokotela wakho. Ungalishintshi inani leyeza osilithatha ngaphandle kokunqunywa ngudokotela wakho. Leli leyeza kufanele libe neNcwadi Yokunakekela Ukuthola Iyeza. Funda futhi ulandele le miyalo ngokucophelela. Buza udokotela wakho uma unemibuzo. Thatha leli leyeza ekuseni ngokudla. Gwinya ithebulethi yokukhulula okwandisiwe yonke. Ungayicwili, ungayiqhekeza, noma ungayikunyathela. Ngesikhathi uthatha ithebulethi yokukhulula okwandisiwe, ingxenye yayo ingadlula ezintweni zakho. Lokhu kuyinto evamile futhi akukho okufanele ukukhathazeke ngakho. Landela ngokucophelela uhlelo lokudla oluhlukile udokotela wakho akunike lona. Lena yingxenye ebaluleke kakhulu yokulawula isifo sakho sikashukela, futhi izosiza leli leyeza ukusebenza kahle. Zivocavoca njalo bese uhlola ushukela egazini lakho noma emchameni njengoba kunqunyiwe. Tshela udokotela wakho uma usesidleni esinamanzi ambalwa noma esinamanzi e-sodium. Inani leli leyeza lizohluka kubantu abahlukene. Landela imiyalo yodokotela wakho noma imiyalo esemthethweni. Ulwazi olulandelayo luhlanganisa kuphela amanani aphakathi aleli leyeza. Uma inani lakho lihlukile, ungalishintshi ngaphandle kokuthi udokotela wakho akuqondise ukuba wenze njalo. Inani leyeza osilithatha lixhomeke emandleni eleyeza. Futhi, inani lezinani olizithatha nsuku zonke, isikhathi esivunyelwe phakathi kwezinani, nobude besikhathi osilithatha leli leyeza kuya ngenkinga yezokwelapha oyisebenzisela lona. Uma uphuthelwa inani leli leyeza, lithatha ngokushesha okukhulu. Noma kunjalo, uma sekusondele isikhathi senani lakho elilandelayo, susa inani eliphosiwe bese ubuyela esimisweni sakho sokuthola inani. Ungawandisi amanani. Gcina leli leyeza esitsheni esivalekile ekushiseni kwegumbi, kude nokushisa, ukufuma, nokukhanya okulungile. Gcina ungawumisisi. Gcina ungafinyeleleki ezinganeni. Ungagcini leyeza eliphelile noma leyeza elingasasetshenziswa. Buza ochwepheshe bezempilo ukuthi kufanele ulahle kanjani noma yiliphi leyeza olungalisebenzisi.
Umshwana wokuzihlangula: I-August iyinkundla yolwazi lwezempilo futhi izimpendulo zayo azihlanganisi iseluleko sezokwelapha. Njalo thintana nochwepheshe bezokwelapha onelayisensi eduze nawe ngaphambi kokwenza noma yiluphi ushintsho.