Yini i-Dapsone: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Dapsone ngumuthi oyi-antibiotic olwa nezifo ezithile ezibangelwa amagciwane futhi osiza ekuphatheni izimo ezithile zesikhumba. Lo muthi othathwa ngomlomo usetshenziswe ngokuphepha amashumi eminyaka ukwelapha izimo ezinjengochoko nokuvimbela izifo ezingamathambo ezingathi sína kubantu abanezinhlelo zokuzivikela ezibuthakathaka.

Ungase unikezwe i-dapsone uma unesimo esidinga ukwelashwa ngama-antibiotic isikhathi eside noma uma udinga ukuvikelwa ezifweni ezithile. Ake sihambe kukho konke okudingeka ukwazi ngalo muthi ukuze uzizwe uqiniseka ngokuphathelwa kwakho.

Yini i-Dapsone?

I-Dapsone ingeyeqembu lama-antibiotics abizwa ngokuthi ama-sulfone asebenza ngokuvimbela amagciwane ukuthi angakhuli futhi azale. Sekukhona kusukela ngeminyaka yama-1940 futhi inerekhodi eliqinisekisiwe lokuphepha nokusebenza kahle uma lisetshenziswa ngendlela efanele.

Lo muthi uhlukile ngoba ungakwazi ukwelapha izifo ezisebenzayo futhi uvimbele ezinye ezintsha ukuthi zingathuthuki. Udokotela wakho angase akuphathe njengengxenye yohlelo lokwelapha oluhlanganisiwe noma njengesinyathelo sokuvimbela esizimele, kuye ngezidingo zakho zempilo ezithile.

Isetshenziselwani i-Dapsone?

I-Dapsone iphatha izimo eziningana ezibalulekile zezokwelapha, lapho uchoko kuyinto eyaziwa kakhulu. Ivame futhi ukunikezwa ukuthi ivimbele isifo esingamathambo esingathi sína esibizwa nge-Pneumocystis pneumonia kubantu abane-HIV noma ezinye izimo ezibuthakathisa uhlelo lokuzivikela.

Nawa amanye amazwi i-dapsone ewasekelayo:

• Uchoko (Isifo sikaHansen) - ngokuvamile ihlanganiswe namanye ama-antibiotics
• Ukuvimbela i-Pneumocystis pneumonia ezigulini ezinokuzivikela okuncane
• I-Dermatitis herpetiformis - isimo sesikhumba esixhunyaniswe nesifo se-celiac
• Ezinye izimo zesikhumba se-autoimmune njengesifo se-linear IgA
• Ukuvimbela i-Toxoplasmosis ezigulini ezithile eziyingozi kakhulu

Udktela wakho uzonquma ukusetshenziswa okulungile kwesimo sakho esithile. Isimo ngasinye sidinga izindlela ezihlukene zokulinganisa nokuqapha.

Isebenza Kanjani I-Dapsone?

I-Dapsone isebenza ngokungenelela endleleni amagciwane enza ngayo i-folic acid, okuyinto ewadingayo ukuze aphile futhi azale. Cabanga ngayo njengokuvimba isithako esibalulekile amagciwane adinga ukwakha izindonga zawo zamaseli nokuzala.

Lo muthi ubhekwa njengomuthi olungile futhi usebenza kancane kancane ngokuhamba kwesikhathi. Ngokungafani namanye ama-antibiotics asebenza ngokushesha, i-dapsone yakha ohlelweni lwakho futhi inikeza ukuvikelwa okuqhubekayo, kwesikhathi eside ngamagciwane aqondiwe.

Lo muthi futhi unezindawo ezilwa nokuvuvukala, okusiza ukuchaza ukuthi kungani usebenza kahle ezimweni ezithile zesikhumba ngaphandle nje kokulwa nezifo.

Kufanele Ngiyithathe Kanjani I-Dapsone?

Thatha i-dapsone ngendlela udokotela wakho ayala ngayo, ngokuvamile kanye ngosuku ngaphandle kokudla noma ngaphandle kokudla. Uma umuthi ukucasula isisu sakho, zama ukuwuthatha ngokudla okulula noma ukudla okulula.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Ungawachobozi, uwahlafune, noma uwaphule amaphilisi ngaphandle uma udokotela wakho ekutshela ngqo ukuthi wenze kanjalo. Ukuwuthatha ngesikhathi esifanayo nsuku zonke kusiza ukugcina amazinga aqhubekayo emzimbeni wakho.

Akudingeki ukuthi ugweme noma yikuphi ukudla okuthile ngenkathi uthatha i-dapsone, kodwa ukugcina ukudla okunempilo kusekela impilo yakho yonke ngesikhathi sokwelashwa. Abanye abantu bathola ukuthi ukuyithatha ngokudla kunciphisa noma yikuphi ukungakhululeki kwesisu.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Dapsone?

Ubude bokwelashwa kwe-dapsone buhlukahluka kakhulu kuye ngesimo sakho. Ngobulephula, ungase uyithathe iminyaka eminingana njengengxenye yokwelashwa okuhlanganisiwe. Ukuvimbela izifo, ungase uyidinge uma nje amasosha akho omzimba esalokhu ekhubazekile.

Ungayeki ukuthatha i-dapsone ngokuzumayo ngaphandle kokukhuluma nodokotela wakho kuqala. Ukuyeka ngokushesha kungavumela izifo ukuthi zibuye noma zibe zimbi. Umhlinzeki wakho wezempilo uzoqapha inqubekela phambili yakho futhi alungise ubude bokwelashwa ngokuya ngokuthi usabela kanjani.

Ezimweni ezithile ezifana ne-dermatitis herpetiformis, ungase udinge i-dapsone izinyanga noma iminyaka ukuze ugcine izimpawu zilawulwa. Udokotela wakho uzobuyekeza njalo ukuthi usayidinga yini imithi.

Yiziphi Izimo Ezingezinhle Ze-Dapsone?

Abantu abaningi bayayibekezelela i-dapsone, kodwa njengayo yonke imithi, ingabangela imiphumela engemihle. Izindaba ezinhle ukuthi imiphumela engemihle engathi sína ayivamile uma imithi isetshenziswa ngendlela efanele futhi iqashwe njalo.

Nansi imiphumela engemihle evame kakhulu ongase uyithole:

• Isicanucanu noma isisu esibuhlungu
• Ikhanda elibuhlungu
• Isiyezi
• Ukulahlekelwa isifiso sokudla
• Ukuqubuka kwesikhumba okuncane
• Ukukhathala

Le miphumela engemihle ivame ukuthuthuka njengoba umzimba wakho ujwayela imithi. Nokho, i-dapsone ngezinye izikhathi ingabangela imiphumela engathi sína edinga ukunakekelwa kwezokwelapha ngokushesha.

Xhumana nodokotela wakho ngokushesha uma uhlangabezana nanoma yiziphi zalezi zimpawu ezingathi sína:

• Ukuphendula kwesikhumba okukhulu noma ukuqubuka okusabalale
• Ukulimala okungavamile noma ukuphuma kwegazi
• Umkhuhlane oqhubekayo noma umphimbo obuhlungu
• Ukuphuzi kwesikhumba noma amehlo
• Umchamo omnyama noma izitulo eziphaphathekayo
• Ukukhathala okukhulu noma ubuthakathaka
• Ukuphefumula kanzima

Enye imiphumela engemihle engavamile kodwa ebalulekile yisimo esibizwa nge-methemoglobinemia, lapho igazi lakho lingathwali umoya-mpilo ngendlela efanele. Yingakho udokotela wakho engase ayalele ukuhlolwa kwegazi njalo ukuze aqaphe amazinga akho.

Ubani Ongafanele Athole I-Dapsone?

I-Dapsone ayifanele wonke umuntu, futhi udokotela wakho uzobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Abantu abanezimo ezithile noma abathatha imithi ethile bangase badinge ukwelashwa okuhlukile.

Akufanele uthathe i-dapsone uma:

• Unokungezwani komzimba ne-dapsone noma imithi ye-sulfa
• Unokugula okukhulu kwegazi
• Unesimo esibizwa ngokuthi i-glucose-6-phosphate dehydrogenase (G6PD) deficiency
• Unenkinga enkulu yenhliziyo, isibindi, noma isifo sezinso

Udktela wakho uzophinda asebenzise ukuqapha okwengeziwe uma une-asthma, izifo zegazi, noma usebenzisa eminye imithi ethile. Abesifazane abakhulelwe nabancelisayo badinga ukucatshangelwa okukhethekile, nakuba i-dapsone ingase ngezinye izikhathi isetshenziswe uma izinzuzo zidlula izingozi.

Amagama Omkhiqizo we-Dapsone

I-Dapsone iyatholakala njengomuthi ojwayelekile, okusho ukuthi uzovame ukuyibona ilebuliwe ngokuthi "dapsone" ekhemisi. Uhlobo olujwayelekile lusebenza kahle njengoba kwenza izinhlobo ezinamagama omkhiqizo futhi ngokuvamile lubiza kancane.

Kwamanye amazwe, ungase uthole i-dapsone ngaphansi kwamagama omkhiqizo afana ne-Avlosulfon, kodwa uhlobo olujwayelekile luvame ukunqunywa. Umuthi wakho wekhemisi angakusiza ukuthi uqonde ukuthi iyiphi inguqulo oyitholayo.

Ezinye Izindlela ze-Dapsone

Uma i-dapsone ingakulungele, imithi eminingi ehlukile ingelapha izimo ezifanayo. Enye indlela engcono kakhulu incike esimweni sakho esithile kanye nezici zezempilo zomuntu ngamunye.

Ukuvimbela i-Pneumocystis pneumonia, ezinye izindlela zihlanganisa:

• Trimethoprim-sulfamethoxazole (okuvame kakhulu ukukhethwa kokuqala)
• Atovaquone
• Pentamidine (ifomu eliphefumulwayo)

Ezimweni zesikhumba ezifana ne-dermatitis herpetiformis, udokotela wakho angase acabange ukwelashwa okungaphezulu noma eminye imithi yomlomo. Enye indlela ngayinye inezinzuzo zayo kanye nemiphumela engemihle engase ibe khona ukuthi umhlinzeki wakho wezempilo uzoxoxa nawe.

Ingabe i-Dapsone Ingcono Kune-Trimethoprim-Sulfamethoxazole?

Kokubili i-dapsone ne-trimethoprim-sulfamethoxazole zisebenza ngempumelelo ekuvikeleni i-Pneumocystis pneumonia, kodwa zisebenza ngendlela ehlukile futhi zinezinhlobo ezihlukene zemiphumela engemihle. Akukho noyedwa "ongcono" kunomunye.

I-Trimethoprim-sulfamethoxazole ivame ukuzanywa kuqala ngoba isebenza kahle kakhulu futhi ifundwe kahle. Kodwa-ke, i-dapsone iba yindlela ekhethwayo lapho abantu bengakwazi ukubekezelela i-trimethoprim-sulfamethoxazole noma lapho ingafaneleki ngenxa yezinye izizathu.

Udktela wakho uzokhetha umuthi ofanele isimo sakho esithile, ecabangela izinto ezinjengezinye izimo zakho zempilo, imithi oyithathayo, nanoma yikuphi ukungezwani komzimba okukhona.

Imibuzo Evame Ukubuzwa Mayelana ne-Dapsone

Ingabe i-Dapsone iphephile kubantu abanezifo zezinso?

I-Dapsone ingasetshenziswa kubantu abanezifo zezinso, kodwa idinga ukuqapha ngokucophelela futhi mhlawumbe kulungiswe umthamo. Udktela wakho uzocabangela ukuthi izinso zakho zisebenza kahle kangakanani lapho enquma ukuthi i-dapsone ikufanele yini.

Uma unezinkinga zezinso, udktela wakho angase aqale ngomthamo ophansi futhi aqaphe amazinga egazi lakho kaningi. Umuthi ucutshungulwa yisibindi sakho ngaphezu kwezinso zakho, okungenza kube yindlela efanelekile yabanye abantu abanezifo zezinso.

Ngingenzani uma ngiphuzile i-Dapsone eningi ngengozi?

Uma ngengozi uphuze i-dapsone eningi kunaleyo ebekiwe, xhumana nodktela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuphuza okuningi kungabangela imiphumela emibi engathi sína, okuhlanganisa nezinkinga ngekhono legazi lakho lokuthwala umoya-mpilo.

Ungalindi ukubona ukuthi uzizwa ulungile yini. Noma ngabe awuziboni izimpawu ngokushesha, kubalulekile ukuthola iseluleko sezokwelapha. Gcina ibhodlela lomuthi unawe lapho ushayela ucingo noma ufuna usizo ukuze abahlinzeki bezempilo bazi kahle ukuthi yini nokuthi ungakanani oyiphuzile.

Ngingenzani uma ngiphuthelwe umthamo we-Dapsone?

Uma uphuthelwe umthamo we-dapsone, yithathe ngokushesha lapho ukhumbula, ngaphandle kokuthi sekuseduze isikhathi somthamo wakho olandelayo. Kuleso simo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe. Lokhu kungandisa ingozi yakho yemiphumela emibi ngaphandle kokuthuthukisa ukusebenza komuthi. Uma uvame ukukhohlwa imithamo, cabangela ukusetha i-alamu yansuku zonke noma usebenzise umhleli wamaphilisi.

Ngingayeka nini ukuphuza i-Dapsone?

Misa ukuthatha i-dapsone kuphela uma udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Isikhathi sincike esimweni sakho esithile nokuthi usabela kanjani ekwelashweni.

Ukuvimbela ukutheleleka, kungase kudingeke uqhubeke nokuthatha i-dapsone uma nje amasosha akho omzimba esengozini. Ukuze welashwe izifo ezisebenzayo, ngokuvamile uzodinga ukuqeda inkambo ephelele ngisho noma uzizwa ungcono. Udokotela wakho uzoqapha inqubekela phambili yakho futhi akwazise uma sekufanele uyeke.

Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Dapsone?

Ngokuvamile kungcono ukunciphisa utshwala ngenkathi uthatha i-dapsone, njengoba kokubili kungathinta isibindi sakho. Nakuba ukusetshenziswa kotshwala ngokulinganisela kungavunyelwe ngokuqinile, ukuphuza ngokweqile kungakhuphula ingozi yakho yezinkinga zesibindi futhi kungase kwenze ezinye izinto ezingezinhle zibe zimbi kakhulu.

Xoxa nodokotela wakho mayelana nokusetshenziswa kotshwala, ikakhulukazi uma uthatha i-dapsone isikhathi eside. Bangakunikeza iseluleko esiqondene nawe esisekelwe empilweni yakho yonke neminye imithi ongase uyithathe.