Yini i-Diethylcarbamazine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni Nokunye

I-Diethylcarbamazine iyimithi kadokotela elwa nezibungu ezingcolisa umzimba wakho. Yenzelwe ngqo ukwelapha izifo ezibangelwa izibungu ezithile eziyindilinga kanye nezibungu ezinjengentambo ezingathinta uhlelo lwakho lwe-lymphatic, igazi, nezicubu. Le mithi isisize abantu ukuthi balulame ezifweni ezingcolisa umzimba amashumi eminyaka futhi isahlala ingenye yezindlela zokwelapha eziphumelela kakhulu ezitholakalayo.

Yini i-Diethylcarbamazine?

I-Diethylcarbamazine iyimithi elwa nezibungu eyingxenye yeqembu lezidakamizwa elibizwa ngokuthi ama-anthelmintics. Cabanga ngayo njengokwelashwa okuqondiwe okuhlasela ngqo izibungu ezingcolisa umzimba wakho. Imithi isebenza ngokukhubaza nokubulala lezi zibungu, ivumela amasosha akho omzimba ukuthi azisuse ngokwemvelo.

Le mithi iza ngesimo samaphilisi futhi ithathwa ngomlomo. Isetshenziswe ngokuphepha iminyaka eminingi futhi ithathwa njengendlela yokwelapha esezingeni eliphezulu lezifo ezithile ezingcolisa umzimba. Le mithi iphumelela ikakhulukazi kuma-microfilariae, okuyizibungu ezincane zezibungu ezingcolisa umzimba ezihamba egazini lakho.

Isetshenziselwani i-Diethylcarbamazine?

I-Diethylcarbamazine iphatha izifo ezithile ezingcolisa umzimba ezithinta izigidi zabantu emhlabeni wonke. Le mithi inikezwa ikakhulukazi i-lymphatic filariasis, eyaziwa nangokuthi i-elephantiasis, ebangelwa izibungu ezinjengentambo ezivimba imithambo yakho ye-lymphatic.

Le mithi futhi iphatha ngempumelelo i-loiasis, isifo esibangelwa isibungu samehlo sase-Afrika esingahamba ngaphansi kwesikhumba sakho futhi ngezinye izikhathi siwele iso lakho. Ngaphezu kwalokho, isetshenziselwa i-tropical pulmonary eosinophilia, isimo samaphaphu esibangelwa ukusabela kwamasosha akho omzimba ezibungwini ze-filarial.

Ngokuvamile, odokotela bangase babhalele i-diethylcarbamazine ezinye izifo ezinamaparasite njenge-visceral larva migrans, lapho izibungu ze-roundworm zihamba ngamalunga akho. Udokotela wakho uzoqaphela ukuthi lo muthi ulungele isimo sakho esithile ngokusekelwe ezivivinyweni zaselabhorethri kanye nezimpawu zakho.

Isebenza Kanjani I-Diethylcarbamazine?

I-Diethylcarbamazine ithathwa njengomuthi olinganiselwe oqinile wokulwa namaparasite osebenza ngezindlela eziningi. Lo muthi uphazamisa ukusebenza kwemisipha yamaparasite, okubenza bakhubazeke futhi ekugcineni bafe. Futhi kwenza amaparasite abonakale kakhulu ohlelweni lwakho lomzimba lokuzivikela, okusiza umzimba wakho ukuthi uwaqede ngempumelelo.

Lo muthi usebenza kahle ikakhulukazi kuma-microfilariae, izibungu ezincane ezizungeza egazini lakho. Lapho la maparasite efa, akhipha izinto ezingabangela ukusabela okuvuvukalayo emzimbeni wakho. Yingakho abanye abantu behlangabezana nemiphumela emibi lapho beqala ukwelashwa, njengoba uhlelo lwabo lomzimba lokuzivikela lusabela kumaparasite afayo.

Lo muthi ufinyelela emazingeni aphezulu egazini lakho kungakapheli ihora elingu-1-2 ngemva kokuwuthatha futhi uqhubeka nokusebenza amahora amaningi. Umzimba wakho usebenza futhi uqede umuthi ngezinsimbi zakho, yingakho abantu abanezinkinga zezinso bangase badinge imithamo elungisiwe.

Kufanele Ngiyithathe Kanjani I-Diethylcarbamazine?

Thatha i-diethylcarbamazine ngendlela eqondile udokotela wakho ayalela ngayo, ngokuvamile ngokudla noma ngemva kokudla ukuze kuncishiswe ukuphazamiseka kwesisu. Lo muthi uvame ukuthathwa izikhathi ezi-2-3 ngosuku izinsuku eziningana kuya emavikini, kuye ngokuthi ukutheleleka kwakho okuthile nokuthi umzimba wakho usabela kanjani ekwelashweni.

Gwinya amaphilisi wonke ngengilazi yamanzi egcwele. Ukuthatha umuthi ngokudla kusiza umzimba wakho ukuthi uwumunce kangcono futhi kunciphisa amathuba okuba nesicanucanu noma ukungakhululeki kwesisu. Abanye odokotela batusa ukuthi uthathe nobisi noma ukudla okulula uma uhlangabezana nokucasuka kwesisu.

Udktela wakho angase akuqale ngomthamo ophansi bese ewunyusa kancane kancane ezinsukwini ezimbalwa zokuqala. Le ndlela isiza ukunciphisa imiphumela emibi engenzeka lapho inani elikhulu lezigcilikidi lifa ngokushesha. Ungalokothi weqe imithamo noma uyeke ukuthatha imithi ngaphambi kwesikhathi, ngisho noma uzizwa ungcono, ngoba lokhu kungaholela ekwehlulekeni kokwelashwa.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Diethylcarbamazine?

Ubude bokwelashwa nge-diethylcarbamazine buhlukahluka kakhulu kuye ngokuthi yisiphi isifo sakho esithile sezigcilikidi. Nge-lymphatic filariasis, ungase uthathe imithi izinsuku eziyi-12-21, kuyilapho i-loiasis ngokuvamile idinga amasonto ama-2-3 okwelashwa.

Udktela wakho uzoqapha ukuqhubeka kwakho ngezivivinyo zegazi nokuhlolwa komzimba ukuze anqume ukuthi kuphephile nini ukuyeka ukwelashwa. Abanye abantu bangase badinge izifundo eziningi zokwelashwa ezihlukaniswe ngamasonto noma izinyanga ukuze baqede ngokuphelele ukutheleleka.

Nge-tropical pulmonary eosinophilia, ukwelashwa kuvame ukuthatha amasonto ama-2-3, kodwa udktela wakho angase akwandise lokhu ngokuya ngezimpawu zakho nemiphumela yokuhlolwa. Qedela yonke inkambo yokwelashwa ngisho noma uqala ukuzizwa ungcono, ngoba ukuyeka ngaphambi kwesikhathi kungavumela izigcilikidi ezisele ukuthi zande futhi zibangele ukuthi ukutheleleka kubuye.

Yiziphi Imiphumela Emibi Ye-Diethylcarbamazine?

Imiphumela emibi evela ku-diethylcarbamazine ivame ukwenzeka ngoba amasosha akho omzimba asabela ezigcilikidini ezifela emzimbeni wakho. Abantu abaningi bahlangabezana nokungakhululeki okuthile ezinsukwini ezimbalwa zokuqala zokwelashwa, kodwa le miphumela ngokuvamile iyathuthuka njengoba umzimba wakho ujwayela imithi.

Imiphumela emibi evamile abantu abaningi abayitholayo ihlanganisa:

• Ikhanda elibuhlungu nesiyezi
• Isicanucanu nokuhlanza
• Umkhuhlane nokubanda
• Ubuhlungu bemisipha namalunga
• Ukukhathala nobuthakathaka
• Ukulahlekelwa isifiso sokudla

Lezi zimpawu zivame ukufinyelela ezingeni eliphezulu phakathi kwezinsuku zokuqala ezi-2-3 zokwelashwa bese zincipha kancane kancane. Udokotela wakho angase ancome imithi yokwelapha ubuhlungu etholakala ngaphandle kwe-oda noma imithi elwa nokuvuvukala ukusiza ukuphatha le miphumela.

Imiphumela emibi engathi sína ingenzeka, ikakhulukazi kubantu abanezifo ezinzima ze-parasitic. Lezi zimo zenzeka lapho inani elikhulu lama-parasites lifa ngasikhathi sinye, likhipha izinto ezivuthayo egazini lakho.

Imiphumela emibi engathi sína edinga ukunakekelwa kwezempilo ngokushesha ihlanganisa:

• Ukuphendula okukhulu komzimba okunzima ngokuphefumula noma ukuvuvukala
• Ubuhlungu obukhulu emehlweni noma izinguquko ekuboneni
• Ubuhlungu obukhulu besisu
• Ubunzima bokuchama noma igazi emchameni
• Ukushaywa yisithuthwane noma ukudideka okukhulu
• Ubuhlungu besifuba noma ukushaya kwenhliziyo okungajwayelekile

Abantu abane-loiasis bangase bahlangabezane nokuphendula okuthile lapho izibungu ezindala zifela ezindaweni ezizwelayo njengamehlo noma ubuchopho. Udokotela wakho uzokuqapha eduze uma unezifo zalolu hlobo.

Ubani Ongafanele Athathe I-Diethylcarbamazine?

I-Diethylcarbamazine ayifanele wonke umuntu, futhi udokotela wakho uzohlola ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Abantu abanezimo ezithile bangase babhekane nezingozi ezengeziwe noma izinkinga ezivela kule mithi.

Akufanele uthathe i-diethylcarbamazine uma une:

• Ukungezwani okwaziwayo ne-diethylcarbamazine noma imithi efanayo
• Isifo esibi sezinso noma ukwehluleka kwezinso
• Izifo zamehlo ezisebenzayo noma ukuhlinzwa kwamehlo kwakamuva
• Izimo zenhliziyo ezinzima noma umfutho wegazi ophezulu ongagadiwe
• Izifo zokushaywa yisithuthwane ezisebenzayo

Ukuqapha okukhethekile kuyadingeka kumaqembu athile abantu. Abesifazane abakhulelwe kufanele bathathe le mithi kuphela uma izinzuzo zikhuphuka ngokusobala izingozi, njengoba ukuphepha ngesikhathi sokukhulelwa kungakahlolisiswa ngokugcwele. Abesifazane abancelisa kufanele baxoxe ngezindlela ezingezinye nodokotela wabo, njengoba imithi ingadlulela obisini lwebele.

Abantu abane-onchocerciasis (ubumpumputhe bomfula) akufanele nanini bathathe i-diethylcarbamazine, njengoba ingabangela ukulimala kwamehlo okukhulu nobumpumputhe. Udokotela wakho uzohlola lesi simo ngaphambi kokuqala ukwelashwa. Izingane ezingaphansi kweminyaka emi-4 ngokuvamile zithola imithamo elungisiwe ngokusekelwe esisindweni sabo kanye neminyaka yobudala.

Amagama e-Brand e-Diethylcarbamazine

I-Diethylcarbamazine itholakala ngaphansi kwamagama amaningi e-brand ngokuya ngendawo yakho kanye nekhemisi. Igama le-brand elivamile kakhulu yi-Hetrazan, esetshenziswe amashumi eminyaka ukwelapha izifo ze-parasitic emhlabeni wonke.

Amanye amagama e-brand afaka i-Banocide ne-Carbilazine, nakuba ukutholakala kuhluka ngokuya ngezwe nesifunda. Kwezinye izindawo, umuthi utholakala kuphela njengefomula ejwayelekile, esebenza ngempumelelo njengama-brand-name versions.

Ikhemisi yakho ingase ibe nama-brand ahlukene noma ama-generic versions e-diethylcarbamazine. Zonke izindlela ezivunyelwe ziqukethe isithako esifanayo esisebenzayo futhi zinikeza imiphumela yokwelashwa elinganayo, ngakho-ke ungaphendukela ngokuphepha phakathi kwama-brand uma kudingeka.

Ezinye izindlela ze-Diethylcarbamazine

Imithi eminingi ehlukile ingelapha izifo ze-parasitic, nakuba ukukhetha okungcono kuncike esimweni sakho esithile kanye nomlando wezokwelapha. Udokotela wakho uzokhetha ukwelashwa okufanele kakhulu ngokusekelwe ohlotsheni lwe-parasite kanye nezimo zakho zomuntu ngamunye.

Nge-lymphatic filariasis, i-ivermectin ehlanganiswe ne-albendazole isibe ukwelashwa okuthandwayo. Le nhlanganisela ivame ukusetshenziswa ezinhlelweni zokwelashwa ngobuningi futhi ingasebenza kubantu abangakwazi ukubekezelela i-diethylcarbamazine.

Nge-loiasis, i-ivermectin yodwa ingase isetshenziswe, nakuba idinga ukuqapha ngokucophelela njengoba ingabangela nokusabela lapho ama-parasite efa. I-Albendazole ingenye inketho yezinye izifo ze-parasitic, ikakhulukazi lezo ezihilela ama-roundworms emathunjini.

Eminye imithi emisha efana ne-doxycycline iyafundwa ukwelapha izifo ze-filarial ngokugxila emabhaktheriya ahlala ngaphakathi kwamapharasayithi. Udokotela wakho uzoxoxa ngalezi zindlela uma i-diethylcarbamazine ingakulungele.

Ingabe i-Diethylcarbamazine Ingcono Kune-Ivermectin?

Kokubili i-diethylcarbamazine ne-ivermectin ziyimithi ephumelelayo yokulwa namapharasayithi, kodwa zisebenza ngendlela ehlukile futhi zifaneleka kangcono ezimweni ezihlukene. Ukukhetha phakathi kwazo kuncike ekuthelelekeni kwakho okuthile, umlando wezokwelapha, kanye nemigomo yokwelashwa.

I-Diethylcarbamazine ngokuvamile iphumelela kakhulu ekubulaleni izibungu zamapharasayithi ezindala, okuyenza ibe yindlela ekhethwayo yokutheleleka okusunguliwe lapho ufuna ukuqeda amapharasayithi ngokuphelele. Inomlando omude wokusebenzisa kanye nocwaningo olubanzi olusekela ukusebenza kwayo.

I-Ivermectin ivame ukukhethwa ukuvimbela ukudluliselwa kwamapharasayithi kwabanye, njengoba iphumelela kakhulu ekubulaleni ama-microfilariae egazini. Kungase kubangele ukusabela okuncane okukhulu kwabanye abantu, ikakhulukazi labo abanezifo ezinzima.

Udokotela wakho uzocabangela izinto ezinjengohlobo lwe-parasite, ubunzima bokutheleleka, impilo yakho yonke, kanye nemihlahlandlela yokwelashwa yendawo lapho ekhetha phakathi kwale mithi. Ezinye izinhlelo zokwelapha zisebenzisa zombili izidakamizwa ndawonye ukuze zisebenze kahle.

Imibuzo Evame Ukubuzwa Mayelana ne-Diethylcarbamazine

Q1. Ingabe i-Diethylcarbamazine Iphephile Ezigulini Zezifo Zenhliziyo?

Abantu abanezifo zenhliziyo bangavame ukuthatha i-diethylcarbamazine ngokuphepha, kodwa badinga ukuqashwa eduze ngesikhathi sokwelashwa. Imithi ngezinye izikhathi ingabangela izinguquko esigqi senhliziyo noma umfutho wegazi, ikakhulukazi lapho amapharasayithi efa futhi ekhulula izinto ezivuthayo.

Udktela wakho uzohlola isimo senhliziyo yakho ngaphambi kokuqala ukwelashwa futhi angase ancome ukuqapha okwengeziwe noma imithi yokuvikela uhlelo lwakho lwe-cardiovascular. Uma unenhliziyo ehluleka kakhulu noma ukuhlaselwa yinhliziyo kwakamuva, udokotela wakho angase akhethe ezinye izindlela zokwelapha noma alungise umthamo wakho ngokucophelela.

Q2. Kufanele Ngenzeni Uma Ngisebenzisa Ngengozi I-Diethylcarbamazine Eningi Kakhulu?

Uma ngengozi uthatha i-diethylcarbamazine eningi kakhulu, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha. Ukuthatha amanani amaningi kungakhuphula ingozi yemiphumela emibi, okuhlanganisa ukuquleka, ukusabela okukhulu komzimba, nezinkinga ze-cardiovascular.

Ungazami ukuzenza uhlanze ngaphandle uma uqondiswe ngokuqondile ochwepheshe bezokwelapha. Kunalokho, qoqa ulwazi mayelana nokuthi uthathe okungakanani nokuthi nini, bese ufuna ukunakekelwa kwezokwelapha ngokushesha. Izimo eziningi zokweqisa zingalawulwa ngempumelelo ngokunakekelwa okufanele kwezokwelapha.

Q3. Kufanele Ngenzeni Uma Ngeqa Umthamo We-Diethylcarbamazine?

Uma weqa umthamo we-diethylcarbamazine, yithathe ngokushesha lapho ukhumbula, ngaphandle kwalapho sekuseduze isikhathi somthamo wakho olandelayo ohleliwe. Kuleso simo, weqa umthamo oweqiwe bese uqhubeka neshejuli yakho yokulinganisa ejwayelekile.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo oweqiwe, ngoba lokhu kungakhuphula ingozi yakho yemiphumela emibi. Uma uvame ukukhohlwa imithamo, cabanga ukusetha izikhumbuzi noma ukuthatha imithi yakho ngesikhathi esifanayo nsuku zonke ngokudla.

Q4. Ngingayeka Nini Ukuthatha I-Diethylcarbamazine?

Yeka kuphela ukuthatha i-diethylcarbamazine lapho udokotela wakho ekutshela ukuthi kuphephile ukwenza kanjalo. Ukuyeka ukwelashwa ngaphambi kwesikhathi kungavumela izinambuzane ezisele ukuthi zande futhi zibangele ukuthi ukutheleleka kwakho kubuye, okungenzeka ukuthi kwenze kube nzima ukukwelapha.

Udkt wenu uzosebenzisa ukuhlolwa kwegazi, ukuhlolwa ngokomzimba, nokuqapha izimpawu ukuze anqume ukuthi usuqede nini ukwelashwa ngempumelelo. Abanye abantu badinga ukuhlolwa okulandelayo izinyanga eziningana ngemuva kokwelashwa ukuqinisekisa ukuthi ukutheleleka kuqedwe ngokuphelele.

Q5. Ngingakwazi yini ukuphuza utshwala ngenkathi ngithatha i-Diethylcarbamazine?

Kungcono ukugwema utshwala ngenkathi uthatha i-diethylcarbamazine, njengoba utshwala bungandisa ingozi yemiphumela emibi efana nesiyezi, isicanucanu, nokuquleka kwesisu. Utshwala bungaphazamisa nekhono lomzimba lakho lokulwa nezifo ezinamaparasite.

Uma ukhetha ukuphuza utshwala ngezikhathi ezithile, zinciphise ngamanani amancane futhi uqaphele ukuthi uzizwa kanjani. Yeka ukuphuza ngokushesha uma uhlangabezana nemiphumela emibi eyengeziwe noma uzizwa ungaphilile. Hlala uxoxa ngokusebenzisa utshwala nodokotela wakho, ikakhulukazi uma unezinkinga zesibindi noma izinso.