Yini i-Dihydroergotamine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Dihydroergotamine iyimithi kadokotela esiza ukumisa ikhanda elibuhlungu elibangelwa yi-migraine kanye namaqembu uma liqala. Ingaphansi kweqembu lemithi ebizwa ngokuthi ama-ergot alkaloids, asebenza ngokunciphisa imithambo yegazi ebuchosheni bakho ukuze kuncishiswe ubuhlungu obukhulu obuhambisana nala makhanda abuhlungu.

Le mithi ivamise ukunikezwa ngomjovo uma udinga ukukhululeka okusheshayo ku-migraine engaphenduli kwezinye izindlela zokwelapha. Cabanga ngayo njengomuthi wokusiza ongena uma imithi yakho evamile yekhanda ingasebenzi.

Yini i-Dihydroergotamine Esetshenziselwa Yona?

Umjovo we-Dihydroergotamine usetshenziselwa ikakhulukazi ukwelapha ukuhlaselwa kwe-migraine okukhulu kanye namakhanda amaqembu. Udokotela wakho uzokunika lo muthi uma uhlangabezana nesigameko sekhanda elibuhlungu elidinga ukunakwa ngokushesha.

Umuthi usebenza kahle kakhulu uma usetshenziswa ekuqaleni kophawu lwe-migraine noma ikhanda leqembu. Awenzelwe ukuvimbela amakhanda ukuthi angabi khona ekuqaleni, kodwa kunalokho ukuwamisela uma eseqalile.

Abanye odokotela basebenzisa i-dihydroergotamine ukwelapha isimo esingavamile esibizwa ngokuthi i-orthostatic hypotension, lapho umfutho wegazi lakho wehla kakhulu uma usukuma. Kodwa-ke, lokhu ukusetshenziswa okungavamile komuthi.

Isebenza Kanjani i-Dihydroergotamine?

I-Dihydroergotamine ithathwa njengomuthi onamandla aphakathi nendawo oqondise imithambo yegazi ebuchosheni bakho. Uma une-migraine, imithambo ethile yegazi iyavuvukala futhi yanda, okufaka isandla ebuhlungwini obuzwayo.

Lo muthi usebenza ngokubopha kuma-receptors athile emithanjeni yakho yegazi futhi ubangele ukuthi anciphe futhi abuyele osayizini ojwayelekile. Le nqubo isiza ukunciphisa ukuvuvukala nokucindezela okubangela ubuhlungu bekhanda lakho.

Ifomu lokujova lisebenza ngokushesha kunezibhebhe ngoba liqondana ngqo emithanjeni yakho yegazi. Ungase uqale ukuzwa ukukhululeka phakathi kwemizuzu eyi-15 kuya kwengama-30 ngemuva kokuthola umjovo, nakuba wonke umuntu esabela ngendlela ehlukile.

Ngingayithatha kanjani i-Dihydroergotamine?

Umjovo we-Dihydroergotamine uvame ukunikezwa ngumhlinzeki wezempilo endaweni yezokwelapha njengasehhovisi likadokotela, emtholampilo, noma esibhedlela. Umuthi ungafakwa emsipheni, ngaphansi kwesikhumba, noma ngqo emthanjeni, kuye ngesimo sakho esithile.

Akudingeki ukhathazeke ngokuthatha lo muthi ngokudla noma esiswini esingenalutho ngoba unikezwa njengomjovo. Kodwa-ke, ukuhlala unamanzi ngaphambi nangemva kokuthola umjovo kungasiza umzimba wakho ukuthi usebenze umuthi ngempumelelo.

Isikhathi sokuthi uthole umjovo sibalulekile. Isebenza kahle kakhulu uma inikezwa ekuqaleni kwesigaba se-migraine noma i-cluster headache, okungcono phakathi nehora lokuqala lokuqala kwezimpawu.

Ngingayithatha isikhathi esingakanani i-Dihydroergotamine?

Umjovo we-Dihydroergotamine uhloselwe ukusetshenziswa kwesikhashana ngesikhathi sezigaba zekhanda elibuhlungu elibukhali. Ngeke uthathe lo muthi nsuku zonke njengeminye imithi yokuvimbela ikhanda.

Abantu abaningi bathola umjovo owodwa esigabeni ngasinye sekhanda elibuhlungu, nakuba udokotela wakho engase ancome umthamo wesibili uma ikhanda lakho libuya kungakapheli amahora angama-24. Inani eliphelele ongalamukela ngokuphepha lilinganiselwe ukuvimbela imiphumela engemihle engaba khona.

Umhlinzeki wakho wezempilo uzoqoka uhlelo olufanele lokulinganisa ngokusekelwe ekutheni uvame kangakanani ukuzwa ikhanda elibuhlungu elibukhali nokuthi usabela kahle kangakanani emuthini. Abanye abantu bangase badinge imijovo masonto onke, kanti abanye bangase bayidinge ngezikhathi ezithile kuphela.

Yiziphi imiphumela emibi ye-Dihydroergotamine?

Njengazo zonke izidakamizwa, i-dihydroergotamine ingabangela imiphumela emibi, nakuba abantu abaningi beyibekezelela kahle uma isetshenziswa ngendlela efanele. Ukuqonda okulindelekile kungakusiza ukuthi uzizwe ulungile futhi ungakhathazeki ngokuthola umjovo.

Imiphumela emibi evame kakhulu ongase uyithole ihlanganisa isicanucanu, ukuhlanza, kanye nesiyezi esincane. Lezi zimpawu zivame ukuthuthuka emahoreni ambalwa njengoba umuthi usebenza emzimbeni wakho.

Nawa amanye amiphumela emibi ebikwa kaningi evame ukuba mncane noma esimaphakathi:

• Isicanucanu nokungakhululeki kwesisu
• Ukuqina kwemisipha noma ukucasuka
• Ukuzwa ukuluma ezandleni noma ezinzwaneni zakho
• Isiyezi esincane noma ukukhathala
• Ukwanda kwesikhashana kwengcindezi yegazi
• Ukukhathala noma ukozela

Le miphumela emibi ejwayelekile ngokuvamile iyazixazulula yona futhi ayidingi ukungenelela kwezokwelapha. Kodwa-ke, ukwazisa umhlinzeki wakho wezempilo nganoma yiziphi izimpawu ozitholayo kubasiza ukuthi baqaphele ukusabela kwakho emuthini.

Kukhona neminye imiphumela emibi engavamile kodwa ebucayi edinga ukunakekelwa kwezokwelapha ngokushesha. Nakuba lokhu kwenzeka ngezikhathi ezithile, kubalulekile ukuyazi ukuze ukwazi ukufuna usizo uma kudingeka.

Imiphumela emibi ebucayi edinga ukunakekelwa kwezokwelapha ngokushesha ihlanganisa:

• Ubuhlungu obukhulu besifuba noma ukuqina
• Ukuphefumula kanzima noma ukuphefumula
• Ubuhlungu obukhulu besisu
• Ukuba ndikindiki noma ubuthakathaka ezingalweni noma emilenzeni yakho
• Ushintsho embonweni noma ekukhulumeni
• Izimpawu zokuncipha kokugeleza kwegazi ezingxenyeni zakho, njengeminwe nezinyawo eziluhlaza noma eziphaphathekayo

Uma uhlangabezana nanoma yiziphi lezi zimpawu ezibucayi kakhulu, xhumana nomhlinzeki wakho wezempilo ngokushesha noma funa ukunakekelwa kwezimo eziphuthumayo. Lezi zimpawu zingabonisa ukuthi umuthi uthinta ukujikeleza kwegazi lakho ngezindlela ezidinga ukunakekelwa okusheshayo.

Ubani Ongafanele Athathwe I-Dihydroergotamine?

I-Dihydroergotamine ayiphephile kuwo wonke umuntu, futhi udokotela wakho uzobukeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuyinika. Izimo ezithile zempilo nemithi kungenza lokhu kwelashwa kungafaneleki noma kube yingozi.

Akufanele uthole i-dihydroergotamine uma unesifo senhliziyo, okuhlanganisa isifo semithambo yenhliziyo, ukuhlaselwa yinhliziyo kwangaphambili, noma ukushaya kwenhliziyo okungajwayelekile. Umphumela womuthi emithanjeni yegazi ungenza inhliziyo esivele ibuthakathaka ibe nomthwalo owengeziwe.

Abantu abanomfutho wegazi ophezulu ongagadiwe kufanele futhi bagweme lo muthi, njengoba ungenza umfutho wegazi ukuthi ukhuphuke nakakhulu. Ngokufanayo, uma unezinkinga ngokujikeleza kwegazi noma uke waba nesitroko, lo muthi ungenza lezi zimo zibe zimbi nakakhulu.

Nawa amanye amakhambi okwelapha i-dihydroergotamine engaphephile:

• Noma yiluphi uhlobo lwesifo senhliziyo noma izinkinga zokushaya kwenhliziyo
• Umfutho wegazi ophezulu ongagadiwe
• Isitroko sangaphambilini noma i-mini-stroke
• Isifo esibi sesibindi noma sezinso
• Ukukhulelwa noma ukuncelisa
• Izifo ezithile zemithambo yegazi

Ngaphezu kwalokho, akufanele uthole i-dihydroergotamine uma usuvele usebenzisa imithi ethile engase ihlangane nayo ngendlela eyingozi. Lokhu kuhlanganisa ama-antibiotics athile, imithi yokulwa nesikhunta, kanye nemithi ye-HIV.

Umhlinzeki wakho wezempilo uzobukeza yonke imithi yakho yamanje nezimo zempilo ukuze aqiniseke ukuthi i-dihydroergotamine iphephile kuwe. Ukwethembeka ngokuphelele ngomlando wakho wezokwelapha kusiza ekuqinisekiseni ukuthi uthola ukwelashwa okuphephe kakhulu nokusebenzayo.

Amagama Omkhiqizo we-Dihydroergotamine

I-Dihydroergotamine injection itholakala ngaphansi kwamagama amaningi omkhiqizo, ne-D.H.E. 45 iyona engajwayelekile ukunikezwa e-United States. Leli gama lomkhiqizo lisiza ukuyihlukanisa nezinye izinhlobo zomuthi.

Ungase futhi uhlangane nomuthi ngaphansi kwegama lomkhiqizo elithi Migranal, nakuba lokhu ngokuvamile kubhekisela kunguqulo ye-nasal spray kunokujova. Ezinye izikhungo zezempilo zingase zisebenzise izinguqulo ezivamile ze-dihydroergotamine injection, eziqulathe isithako esifanayo esisebenzayo kodwa zingase zibe ngabiza kancane.

Kungakhathaliseki igama lomkhiqizo, zonke izinguqulo ze-dihydroergotamine injection zisebenza ngendlela efanayo futhi zinesiphumo esifanayo. Umhlinzeki wakho wezempilo uzokhetha inketho efanele kakhulu ngokusekelwe ekutholakaleni nasezidingweni zakho ezithile.

Ezinye izindlela ze-Dihydroergotamine

Uma i-dihydroergotamine ingakulungele noma inganikezi ukukhululeka okwanele, kunezindlela eziningana zokwelapha ezingenye ezitholakalayo zama-migraines abukhali kanye nekhanda leqembu. Udokotela wakho angakusiza ukuthi uhlole lezi zinketho ukuze uthole okukulungele kakhulu isimo sakho.

Ama-triptans ayisigaba esithandwayo semithi ye-migraine esebenza ngendlela efanayo ne-dihydroergotamine kodwa angase abe nemiphumela emincane emibi kwabanye abantu. Lokhu kufaka phakathi imithi efana ne-sumatriptan, rizatriptan, kanye ne-zolmitriptan, etholakala ngemijovo, amaphilisi, noma ama-nasal sprays.

Ngamakhanda eqembu ngokukhethekile, ukwelashwa nge-oxygen ephezulu kungasebenza ngempumelelo futhi cishe akuna miphumela emibi. Abantu abaningi bathola ukuthi ukuphefumula i-oxygen engu-100% ngemaski yobuso imizuzu engu-15-20 kunikeza ukukhululeka okukhulu.

Ezinye izindlela udokotela wakho angazicabangela zihlanganisa:

• Eminye imithi ye-triptan ngezinhlobo ezahlukene
• Ukwelashwa nge-oxygen ephezulu ngamakhanda eqembu
• Imithi elwa nesicanucanu ehlanganiswe nezidambisi zokucasuka
• Imithi emisha efana ne-gepants noma ama-ditans
• Izinqubo zokuvimba imizwa ezimweni ezinzima

Ukukhethwa kwenye indlela kuncike ohlotsheni lwakho oluthile lekhanda, umlando wezokwelapha, nokuthi usabele kanjani kwezinye izindlela zokwelapha. Ukusebenza eduze nomhlinzeki wakho wezempilo kusiza ukuqinisekisa ukuthi uthola inketho esebenza kahle kakhulu enemiphumela emibi embalwa.

Ingabe i-Dihydroergotamine ingcono kune-Sumatriptan?

Kokubili i-dihydroergotamine ne-sumatriptan ziyimithi esebenzayo yokwelapha ama-migraines aqinile, kodwa zisebenza ngendlela ehlukile kancane futhi zingase zifaneleke kangcono kubantu abahlukene. Akukho noyedwa oncono kunomunye, njengoba ukukhetha okungcono kuncike ezimweni zakho.

I-Dihydroergotamine ivame ukunikeza ukukhululeka okuhlala isikhathi eside futhi inethuba eliphansi lokuthi ikhanda libuye phakathi namahora angama-24. Lokhu kuyenza ibe usizo ikakhulu kubantu abama-migraines abo avame ukubuya ngemva kokwelashwa kokuqala ngeminye imithi.

I-Sumatriptan, ngakolunye uhlangothi, ivame ukusebenza ngokushesha futhi itholakala ngezindlela ezilula njengamaphilisi kanye nezifutho zamakhala. Iphinde ihlotshaniswe nemiphumela emincane, okuyenza ibe yindlela enhle yomugqa wokuqala kubantu abaningi.

Udokotela wakho uzocabangela izici eziningana lapho ekhetha phakathi kwale mithi, okuhlanganisa impilo yenhliziyo yakho, umfutho wegazi, ukuthi udinga ukukhululeka ngokushesha kangakanani, nokuthi ama-migraines akho avame ukuhlala isikhathi esingakanani. Abanye abantu benza ngcono ngomuthi owodwa, kanti abanye bangase badinge ukuzama kokubili ukuze babone ukuthi yini esebenza kangcono.

Imibuzo Evame Ukubuzwa Mayelana ne-Dihydroergotamine

Q1. Ingabe i-Dihydroergotamine iphephile kubantu abanesifo sikashukela?

I-Dihydroergotamine ingasetshenziswa ngokuphepha kubantu abanesifo sikashukela, kodwa idinga ukuqapha okucophelelayo. Umuthi ungathinta ukujikeleza kwegazi, okuyinto esivele iyinkinga kubantu abanesifo sikashukela, ikakhulu uma benezinkinga zesifo sikashukela ezithinta imithambo yegazi labo.

Udokotela wakho uzodinga ukuhlola ukulawulwa kwakho konke kwesifo sikashukela futhi ahlole noma yiziphi izimpawu zezinkinga zesifo sikashukela ngaphambi kokunquma i-dihydroergotamine. Uma une-diabetic neuropathy noma umonakalo wemithambo yegazi, ukwelashwa okuhlukile kungase kube izinketho eziphephe kakhulu.

Q2. Kufanele ngenzeni uma ngisebenzisa i-Dihydroergotamine eningi ngengozi?

Ukweqisa komthamo we-dihydroergotamine kuyisimo esiphuthumayo sezokwelapha esidinga ukunakekelwa ngokushesha. Njengoba le mithi inikezwa abahlinzeki bezempilo, ukweqisa komthamo ngengozi akuvamile, kodwa kungenzeka uma kukhona ukudideka ngemithamo yangaphambilini noma isikhathi.

Izimpawu zokuthatha i-dihydroergotamine eningi zihlanganisa isicanucanu esibi nokuhlanza, isiyezi esikhulu, ikhanda elibuhlungu kakhulu, ukuba ndikindiki noma ukuluma emilenzeni yakho, kanye nezinguquko ekushayeni kwenhliziyo. Uma uhlangabezana nanoma yiziphi zalezi zimpawu ngemva kokuthola umjovo, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha.

Q3. Kufanele Ngenzeni Uma Ngeqisa Umthamo We-Dihydroergotamine?

Njengoba umjovo we-dihydroergotamine usetshenziselwa ukwelapha izigameko zekhanda elibuhlungu elibukhali kunokuba uthathwe ngeshejuli ejwayelekile, akukho umqondo "wokweqa umthamo" ngomqondo wendabuko. Uthola umjovo uma uhlangabezana ne-migraine enkulu noma ikhanda elibuhlungu leqembu.

Uma ikhanda lakho libuya ngemva kokwelashwa kokuqala, xhumana nomhlinzeki wakho wezempilo ukuze uxoxe ngokuthi umjovo wesibili ulungile yini. Ungazami ukulungisa ukwelashwa okweqiwe ngokuthatha imithi eyengeziwe, njengoba lokhu kungaba yingozi.

Q4. Ngingayeka Nini Ukuthatha I-Dihydroergotamine?

Ungayeka ukusebenzisa i-dihydroergotamine noma nini lapho wena nodokotela wakho ninquma ukuthi ayisadingeki noma ayisizi. Njengoba isetshenziselwa kuphela izigameko zekhanda elibuhlungu elibukhali, akukho inqubo yokuhoxisa noma ukunciphisa okudingekayo njengoba kungase kube njalo ngemithi yansuku zonke.

Abantu abaningi baqhubeka benayo i-dihydroergotamine etholakalayo njengokwelashwa kokuhlenga amakhanda abuhlungu kakhulu, ngisho noma bengayidingi njalo. Isinqumo sokuyeka ukuyisebenzisa ngokuvamile sincike ekutheni iphethini yakho yekhanda liyashintsha yini noma uma uthola ezinye izindlela zokwelapha ezisebenza kangcono kuwe.

Q5. Ngingashayela Ngemva Kokuthola I-Dihydroergotamine?

Akufanele ushayele ngokushesha ngemva kokuthola umjovo we-dihydroergotamine. Imithi ingabangela isiyezi, ukozela, kanye nezinguquko ekuqapheliseni kwakho ezingenza ukushayela kungaphephile.

Iningi labahlinzeki bezempilo lincoma ukulinda okungenani amahora angu-2-4 ngemva kokuthola umjovo ngaphambi kokushayela, futhi kuphela uma uzizwa uqaphele ngokuphelele futhi uzinzile. Uma usazwa isiyezi, ukukhathala, noma eminye imiphumela emibi, lungiselela omunye umuntu ukuthi akuqhubele ekhaya noma usebenzise ezinye izindlela zokuthutha.