Yini i-Diphenoxylate kanye ne-Atropine: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Diphenoxylate kanye ne-atropine iyimithi kadokotela esiza ukulawula isifo sohudo ngokunciphisa ukunyakaza kwamathumbu akho. Le mithi ehlanganisiwe iqukethe izithako ezimbili ezisebenzayo ezisebenza ndawonye - i-diphenoxylate yenza umsebenzi omkhulu wokunciphisa isifo sohudo, kuyilapho i-atropine yengezwa ngobuningi obuncane kakhulu ukuvimbela ukusetshenziswa kabi. Ungase wazi le mithi ngegama layo lomkhiqizo elithi Lomotil, futhi ivame ukunqunywa uma ezinye izindlela zokwelapha ezingathengiswa ngaphandle kwekhawunta zingazange zinikeze ukukhululeka okwanele.

Yini i-Diphenoxylate kanye ne-Atropine?

I-Diphenoxylate kanye ne-atropine yinto elawulwayo eyingxenye yeqembu lemithi ebizwa ngokuthi ama-antidiarrheals. Ingxenye ye-diphenoxylate iyinhlanganisela ehlobene ne-opioid esebenza ngqo ohlelweni lwakho lokugaya ukudla, kuyilapho i-atropine iyisithako se-anticholinergic esengezwa ngobuningi obuncane ikakhulukazi njengokuvimbela ukusetshenziswa kabi.

Le mithi ihlukaniswa njengento elawulwayo ye-Schedule V ngoba i-diphenoxylate ihlobene ngamakhemikhali nama-opioids, nakuba ingakhiqizi imiphumela efanayo uma isetshenziswa njengoba kuqondiswe. Inhlanganisela iza ngesimo samaphilisi futhi idinga incwadi kadokotela evela kumhlinzeki wakho wezempilo.

Ngokungafani nemithi elula ye-antidiarrheal engathengiswa ngaphandle kwekhawunta, le nhlanganisela igcinelwe amacala aqhubekayo noma aqinile esifo sohudo adinga ukungenelela okuqinile. Udokotela wakho ngokuvamile uzocabangela le ndlela lapho ezinye izindlela zokwelapha zingasebenzi ngokwanele.

Yini i-Diphenoxylate kanye ne-Atropine Esetshenziselwa Yona?

Le mithi ikakhulukazi inqunyelwe ukwelapha isifo sohudo esibukhali kanye nesifo sohudo esingapheli kubantu abadala kanye nezingane ezineminyaka engaphezu kwengu-13 ubudala. Ilusizo ikakhulukazi uma uhlangabezana nokunyakaza kwamathumbu okuvamile, okuxekethile, noma okumanzi okuphazamisa impilo yakho yansuku zonke.

Udktela wakho angase akunikeze lo muthi wokulwa nohudo olubangelwa izimo ezihlukahlukene, okuhlanganisa i-irritable bowel syndrome, i-inflammatory bowel disease, noma izifo eziqhubeke ngaphandle kokwelashwa okunye. Ngezinye izikhathi futhi isetshenziswa njengengxenye yokwelashwa kwezifo ezithile zokugaya lapho ukulawula ukuhamba kwamathumbu kubalulekile ukuze uzizwe ukhululekile futhi ube nempilo.

Nokho, lo muthi welapha izimpawu zohudo kunokuthi ubhekane nembangela eyinhloko. Umhlinzeki wakho wezempilo uzosebenza nawe ukuthola nokwelapha noma yiziphi izimo ezingaphansi ngenkathi usebenzisa lo muthi ukuhlinzeka ngokuqeda izimpawu.

Kubalulekile ukuqaphela ukuthi lo muthi akufanele usetshenziswe ngohudo olubangelwa izinhlobo ezithile zezifo zamagciwane, njengoba ukunciphisa ukuhamba kwamathumbu kungase kwenze lezi zifo zibe zimbi ngokuvimbela umzimba wakho ukuthi uqede amagciwane ayingozi.

Isebenza Kanjani I-Diphenoxylate ne-Atropine?

I-Diphenoxylate isebenza ngokunciphisa ukuhamba kwamathumbu akho, okwenza umzimba wakho ube nesikhathi esiningi sokumunca amanzi esitulweni futhi kunciphisa ukuvama kokuhamba kwamathumbu. Cabanga ngakho njengokubeka amabhuleki amancane ohlelweni lwakho lokugaya ukudla.

Lo muthi ubopha kuma-opioid receptors emgudwini wakho wamathumbu, okunciphisa isivinini lapho ukudla nodoti kudlula ngohlelo lwakho lokugaya ukudla. Lokhu kuhamba kancane kuvumela amanzi amaningi ukuthi amuncwe, okwenza isitulo sakho sibe nokwakheka okwengeziwe futhi kunciphisa ukuphuthuma kanye nokuvama kokuhamba kwamathumbu.

Ingxenye ye-atropine inenjongo ephindwe kabili - yengeza eminye imiphumela eyengeziwe ye-antispasmodic ukusiza ukuthulisa ukucasuka kwamathumbu, futhi okubaluleke kakhulu, isiza ukuvimbela ukusetshenziswa kabi okungenzeka komuthi. Inani le-atropine libalwa ngokucophelela ukubangela imiphumela engathandeki uma umuntu ethatha amanani amaningi.

Lokhu kuthathwa njengomuthi oqinile ophikisana nohudo, onamandla kakhulu kunezinketho ezingathengiswa ngaphandle kwemvume kadokotela njenge-loperamide, kodwa yakhelwe ukusebenza ikakhulukazi ohlelweni lwakho lokugaya ukudla kunokuthinta umzimba wakho wonke njengemithi enamandla ye-opioid.

Kufanele Ngiyithathe Kanjani I-Diphenoxylate ne-Atropine?

Thatha lo muthi njengoba unjalo njengoba uyalelwe udokotela wakho, ngokuvamile uqala ngamaphilisi ama-2 ekuqaleni, kulandelwe iphilisi elilodwa ngemuva kwesitulo ngasinye esixekethile. Umthamo omkhulu wansuku zonke uvame ukuba ngamaphilisi angu-8 esikhathini samahora angu-24, nakuba udokotela wakho engase akulungise lokhu ngokuya ngesimo sakho esithile.

Ungawathatha lawa maphilisi nokudla noma ngaphandle kokudla, kodwa ukuwathatha ngamanani amancane okudla kungasiza ukunciphisa noma yikuphi ukuphatheka kabi kwesisu. Gwinya amaphilisi wonke ngengilazi yamanzi egcwele - ungasigayi, uhlafune, noma uwaphule njengoba lokhu kungathinta indlela umuthi osebenza ngayo.

Kungcono ukuthatha lo muthi ekuqaleni kwezimpawu zohudo futhi uqhubeke njengoba uqondiswe umhlinzeki wakho wezempilo. Gcina umkhondo wokuthi mangaki amaphilisi owathathe ngosuku ngalunye ukuze ugweme ukweqa umthamo omkhulu onconywayo.

Ngesikhathi uthatha lo muthi, qiniseka ukuthi uhlala unamanzi ngokwanele ngokuphuza uketshezi oluningi olucacile njengamanzi, ama-broths acacile, noma izixazululo ze-electrolyte. Gwema utshwala ngokuphelele ngenkathi usebenzisa lo muthi, njengoba kungakhuphula ingozi yemiphumela emibi engathi sína.

Kufanele Ngiyithathe Isikhathi Esingakanani I-Diphenoxylate ne-Atropine?

Abantu abaningi bathatha lo muthi izinsuku ezimbalwa kuya evikini elilodwa lokuhuda okukhulu, nakuba isikhathi esiqondile sincike esimweni sakho esithile nokuthi izimpawu zakho zithuthuka ngokushesha kangakanani. Udokotela wakho uzohlinzeka ngesiqondiso esicacile sokuthi kufanele uqhubeke isikhathi esingakanani ukuwuthatha.

Ngohudo olukhulu, ngokuvamile uzoyeka ukuthatha umuthi uma ukuhamba kwamathumbu kwakho kubuyela ekuvumelaneni nasekujwayelekeni. Lokhu kuvame ukwenzeka phakathi kwezinsuku ezi-2-3 zokuqala ukwelashwa, nakuba kungathatha isonto ezinye izimo.

Uma usebenzisa lo muthi ngokuqunjelwa okungapheli okuhlobene nesimo esiqhubekayo, udokotela wakho angase akuqokele iminyaka eminingi. Nokho, bazokuqapha eduze futhi bahlole njalo ukuthi ngabe ukuqhubeka nokusebenzisa kuyadingeka futhi kuyazuzisa yini.

Ungalokothi uqhubeke nokuthatha lo muthi isikhathi eside kunokuba uqokiwe, futhi ungayeki ngokuphazima kweso uma ubuthatha isikhathi eside. Udokotela wakho kungadingeka ukuthi anciphise kancane umthamo wakho ukuze avimbele noma yiziphi izimpawu zokuhoxisa, yize lokhu kungavamile ekusetshenzisweni okuvamile kokwelapha.

Ziyini Imiphumela Eceleni ye-Diphenoxylate ne-Atropine?

Njengayo yonke imithi, i-diphenoxylate ne-atropine kungadala imiphumela emibi, yize abantu abaningi behlangabezana nemiphumela emincane kuphela noma abangabi nayo nhlobo. Ukuqonda okufanele ukulindele kungakusiza ukuthi uzizwe ulungiseleleke kakhulu futhi wazi ukuthi ungaxhumana nini nomhlinzeki wakho wezempilo.

Imiphumela emibi ejwayelekile ongase uyithole ihlanganisa ukozela, isiyezi, umlomo owomile, nesicanucanu esincane. Le miphumela ivame ukuba mncane futhi ivame ukuthuthuka njengoba umzimba wakho uzivumela emuthini ezinsukwini ezimbalwa zokuqala zokwelashwa.

Nansi imiphumela emibi ebikwa kaningi ethinta abanye abantu:

• Ukozela noma ukuzwa ukhathele
• Isiyezi noma ukukhathala
• Umlomo owomile
• Isicanucanu noma ukuphatheka kabi kwesisu
• Ikhanda
• Umbono ongacacile
• Ukuqunjelwa (ikakhulukazi uma isifo sohudo siyeka ngokuphelele)

Le miphumela emibi ejwayelekile ivame ukulawuleka futhi yesikhashana. Ukuhlala unamanzi, ukuhamba kancane lapho ushintsha izikhundla, nokugwema ukushayela kuze kube yilapho wazi ukuthi umuthi ukuthinta kanjani kungasiza ekunciphiseni le miphumela.

Abanye abantu bangase babe nemiphumela emibi engavamile kodwa ekhathazayo edinga ukunakekelwa kwezokwelapha. Lokhu kufaka phakathi ukuqunjelwa okukhulu okuhlala izinsuku ezingaphezu kwezimbili, ubuhlungu obukhulu besisu noma ukuvuvukala, ubunzima bokuchama, noma izimpawu zokungezwani komzimba.

Imiphumela emibi engavamile kodwa ebucayi ingenzeka, ikakhulukazi uma uthatha imithi eningi kakhulu noma unezimo ezithile zempilo ezingaphansi:

• Ukuqunjelwa okukhulu nobuhlungu besisu nokuvuvukala
• Ukuphefumula kanzima noma ukuphefumula kancane
• Ukozela okukhulu noma ukudideka
• Ukushaya kwenhliziyo okusheshayo noma isigqi senhliziyo esingajwayelekile
• Ukungezwani komzimba okukhulu okunezinduna, ukuvuvukala, noma ubunzima bokuphefumula
• Izimpawu ze-toxic megacolon (ubuhlungu besisu obukhulu nokuvuvukala)

Uma uhlangabezana nanoma yimiphi yale miphumela emibi, funa usizo lwezokwelapha ngokushesha. Ngenkathi lezi zinkinga zingavamile uma imithi isetshenziswa njengoba kunqunywe, kubalulekile ukuyazi futhi uthathe isinyathelo ngokushesha uma zenzeka.

Ubani Ongafanele Athathwe i-Diphenoxylate kanye ne-Atropine?

Amaqembu amaningana abantu kufanele agweme lo muthi noma awusebenzise ngaphansi kokuqondiswa kwezokwelapha okucophelelayo. Udokotela wakho uzobuyekeza umlando wakho wezokwelapha nesimo sempilo yakho samanje ukuze anqume ukuthi lo muthi uphephile yini kuwe.

Akufanele uthathe lo muthi uma unezinhlobo ezithile zohudo, ikakhulukazi lezo ezibangelwa izifo zamagciwane njenge-Salmonella, Shigella, noma i-E. coli. Ukunciphisa ukunyakaza kwamathumbu akho kulezi zimo kungabamba amagciwane ayingozi ohlelweni lwakho futhi kwenze ukutheleleka kube kubi kakhulu.

Abantu abanezimo ezithile zezokwelapha badinga ukugwema lo muthi ngokuphelele:

• Isifo sesibindi esibi
• Isifo sezinso esibi
• I-Myasthenia gravis (isimo sokukhathala kwemisipha)
• I-Glaucoma (ukwanda kwengcindezi emehlweni)
• I-Ulcerative colitis enkulu noma ezinye izifo zamathumbu ezivuvukalayo ngesikhathi sokuqubuka okukhulu
• Ukuvinjelwa kwamathumbu noma ukuvaleka
• Ukungezwani komzimba okwaziwayo ne-diphenoxylate, atropine, noma imithi ehlobene

Lo muthi awunconyelwe nezingane ezingaphansi kweminyaka engu-13 ubudala, njengoba bezwela kakhulu emiphumeleni yawo futhi bangase babe nezinkinga ezinzima ngisho nangemithamo ejwayelekile.

Abesifazane abakhulelwe nabancelisayo ngokuvamile kufanele bakugweme lokhu kwelapha ngaphandle uma izinzuzo ezingaba khona ziqeda ubungozi. Uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa, xoxa ngezinketho zokwelapha ezingezinye nodokotela wakho.

Abantu abanomlando wokusebenzisa kabi izidakamizwa noma utshwala kufanele basebenzise lo muthi ngokuqapha okukhulu, njengoba uqukethe inhlanganisela ehlobene ne-opioid engaba umlutha, yize ingxenye ye-atropine yenza ukusetshenziswa kabi kungenzeki.

Amagama e-Brand e-Diphenoxylate kanye ne-Atropine

Igama elaziwa kakhulu leli qembu lemithi yi-Lomotil, ebelitholakala iminyaka eminingi futhi laziwa kakhulu ngabahlinzeki bezempilo neziguli. Le nguqulo yegama lomkhiqizo iqukethe izithako ezifanayo ezisebenzayo emazingeni afanayo njengenguqulo ejwayelekile.

Izinhlobo ezijwayelekile ze-diphenoxylate kanye ne-atropine nazo ziyatholakala futhi ziqukethe izithako ezisebenzayo ezifanayo nomkhiqizo wegama lomkhiqizo. Lezi zinketho ezijwayelekile zivame ukungabizi kakhulu ngenkathi zinikeza imiphumela efanayo yokwelapha kanye nephrofayili yokuphepha.

Noma ngabe uthola igama lomkhiqizo noma inguqulo ejwayelekile kuvame ukuncika ekuhlinzekweni komshuwalense wakho, okuthandwa yikhemisi, kanye nokucatshangelwa kwezindleko. Zombili izinhlobo zisebenza ngokulinganayo uma zisetshenziswa njengoba kunqunywe ngumhlinzeki wakho wezempilo.

Ezinye izindlela ze-Diphenoxylate kanye ne-Atropine

Imithi eminingi ehlukile ingasiza ukulawula isifo sohudo, futhi udokotela wakho angase acabangele lezi zinketho ngokuya ngesimo sakho esithile, umlando wezokwelapha, nokuthi uzithola kanjani izindlela zokwelapha ezihlukene.

I-Loperamide (Imodium) iyinye indlela ejwayelekile etholakala ngaphandle kwekhawunta esebenza ngendlela efanayo ngokunciphisa ukunyakaza kwamathumbu. Ivame ukuzanywa kuqala ngesifo sohudo esincane kuya esimaphakathi ngoba sitholakala kalula futhi sinemingcele embalwa kunezinketho zokubhala.

Ezinye izindlela zokubhala udokotela wakho angazicabangela zifaka:

• I-Bismuth subsalicylate (Pepto-Bismol) yokuhuda okuncane nokuphazamiseka kwesisu
• I-Cholestyramine yokuhuda okubangelwa ukungamuncwa kwe-bile acid
• I-Rifaximin yezinhlobo ezithile zokukhula ngokweqile kwamagciwane
• Ama-Probiotics njengokwelashwa okusekelayo ukubuyisela amagciwane amathumbu anempilo
• Imithi ethile eqondiswe ezimweni ezingaphansi njengesifo samathumbu esivuvukalayo

Ukukhetha okunye kuncike kulokho okubangela ukuhuda kwakho, ukuthi izimpawu zakho zinzima kangakanani, nokuthi yiziphi ezinye izimo zezokwelapha ongase ube nazo. Umhlinzeki wakho wokunakekelwa kwezempilo uzosebenza nawe ukuthola inketho yokwelapha efaneleka kakhulu nephumelelayo.

Ingabe i-Diphenoxylate ne-Atropine ingcono kune-Loperamide?

Zombili lezi zithako zisebenza ngokunciphisa ukunyakaza kwamathumbu, kodwa zinezinye izinto ezibalulekile ezenza ngasinye sifaneleke kakhulu ezimweni ezihlukene. Ukukhetha phakathi kwazo kuncike ekuqineni kokuhuda kwakho kanye nezidingo zakho zezokwelapha.

I-Diphenoxylate ne-atropine ngokuvamile zibhekwa njengeziqinile kune-loperamide futhi ngokuvamile zigcinelwe ukuhuda okukhulu noma okuqhubekayo okungazange kuphendule kahle ekwelashweni okungaphezu kwe-counter. Idinga incwadi kadokotela kanye nokuqashwa kwezokwelapha okuseduze.

I-Loperamide inezinzuzo ezithile - itholakala ngaphezu kwe-counter, inokuxhumana okuncane kwemithi, futhi ayithwali imikhawulo yezinto ezilawulwayo. Ivame ukuba yinto yokuqala yokuhuda okuncane kuya okulingene futhi ingasebenza kahle kakhulu kubantu abaningi.

Nokho, i-diphenoxylate ne-atropine ingasebenza kahle kakhulu ekuhudeni okukhulu noma uma i-loperamide ingazange inikeze ukukhululeka okwanele. Ukwengezwa kwe-atropine kungasiza futhi ngokuqina kanye nokungakhululeki kwesisu okwenzeka ngezinye izikhathi okuhambisana nokuhuda okukhulu.

Udokotela wakho uzocabangela izinto ezinjengokuqina kwezimpawu zakho, izimbangela ezingaphansi, eminye imithi oyithathayo, kanye nomlando wakho wezokwelapha lapho enquma ukuthi iyiphi inketho engcono esimweni sakho esithile.

Imibuzo Evame Ukubuzwa Mayelana ne-Diphenoxylate kanye ne-Atropine

Ingabe i-Diphenoxylate kanye ne-Atropine iphephile kubantu abanezifo zenhliziyo?

Abantu abanezifo zenhliziyo bangasebenzisa lo muthi ngokuphepha, kodwa kudingeka ukuqapha ngokucophelela nokucabangela isimo sakho senhliziyo esithile. Ingxenye ye-atropine ngezinye izikhathi ingathinta izinga lenhliziyo nomfutho, ngakho udokotela wakho uzodinga ukuhlola izingozi nezinzuzo.

Uma unezinkinga ezithile zomfutho wenhliziyo, ukuhluleka kwenhliziyo okukhulu, noma usanda kuba nesifo senhliziyo, udokotela wakho angase akhethe ezinye izindlela zokwelapha. Kodwa-ke, kubantu abaningi abanezifo zenhliziyo ezinzile, lo muthi ungasetshenziswa ngokuphepha uma izinzuzo zidlula izingozi.

Njalo yazisa umhlinzeki wakho wezempilo nganoma yiziphi izimo zenhliziyo, imithi oyithathayo ngenhliziyo yakho, nanoma yiziphi izimpawu ezinjengobuhlungu besifuba, ukushaya kwenhliziyo okungajwayelekile, noma ukuphefumula kanzima ngenkathi usebenzisa lo muthi.

Ngingenzani uma ngithatha i-Diphenoxylate kanye ne-Atropine eningi ngengozi?

Uma ngengozi uthatha ngaphezu kwenani elinqunyiwe, xhumana nodokotela wakho noma isikhungo sokulawula ubuthi ngokushesha, ngisho noma ungazizwa ugula okwamanje. Ukweqisa kungabangela izinkinga ezingathí sina ezingase zingaveli ngokushesha.

Izimpawu zokweqisa zihlanganisa ukozela okukhulu, ukudideka, ubunzima bokuphefumula, ukushaya kwenhliziyo okuhamba kancane, ukuqunjelwa okukhulu, noma ukulahlekelwa ukwazi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, funa ukunakekelwa kwezempilo okuphuthumayo ngokushesha.

Ukuthatha i-atropine eningi kungabangela ezinye izimpawu ezinjengesikhumba esibomvu, umkhuhlane, ukushaya kwenhliziyo okusheshayo, noma imibono. Ungalokothi uzame ukuzelapha ngokweqisa - ukuhlolwa kwezokwelapha okuchwepheshile nokwelashwa kubalulekile.

Ngingenzani uma ngiphuthelwa umthamo we-Diphenoxylate kanye ne-Atropine?

Uma uphuthelwa umthamo, wuthatha ngokushesha lapho ukhumbula, kodwa kuphela uma usahlangabezana nohudo. Ungawuthathi umthamo ophuthelwe uma ukuchama kwakho sekubuyele kwesijwayelekile noma uma sekuseduze isikhathi somthamo wakho olandelayo ohleliwe.

Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ulungise umthamo ophuthelwe, ngoba lokhu kungandisa ingozi yakho yemiphumela emibi kanye nokweqisa umthamo. Umuthi wenzelwe ukuthi uthathe njengoba kudingeka ngezimpawu, ngakho ukuphuthelwa umthamo ngokuvamile akuyona inkinga enkulu.

Uma ungaqiniseki ukuthi uzowuthatha yini umthamo ophuthelwe, xhumana nomhlinzeki wakho wezempilo noma usokhemisi ukuze uthole isiqondiso. Bangakusiza ukuthi unqume inkambo engcono kakhulu yesenzo esekelwe esimweni sakho esithile kanye nephethini lezimpawu.

Ngingayeka nini ukuthatha i-Diphenoxylate ne-Atropine?

Ngokuvamile ungaqeda ukuthatha lo muthi uma ukuchama kwakho kubuyela ekujwayelekeni kwesimo kanye nemvamisa, ngokuvamile kungakapheli izinsuku ezimbalwa uqale ukwelashwa. Akunasidingo sokunciphisa kancane umthamo wokusebenzisa isikhashana.

Uma ubuthathe umuthi isikhathi esingaphezu kwesonto elilodwa noma ngesimo esingamahlalakhona, xoxa nodokotela wakho ngaphambi kokuyeka. Bangase bafune ukunciphisa kancane umthamo wakho noma bakuqaphele eduze ngesikhathi sokushintsha.

Ungaqhubeki nokuthatha umuthi uma uhudo lwakho seluphelile, ngoba lokhu kungaholela ekuqineni kwesisu kanye nezinye izinkinga. Kodwa-ke, uma izimpawu zibuyela, ungaqala kabusha ukuzithatha njengoba kunqunywe ngumhlinzeki wakho wezempilo.

Ngingashayela ngesikhathi ngithatha i-Diphenoxylate ne-Atropine?

Kufanele ugweme ukushayela noma ukusebenzisa imishini uze wazi ukuthi lo muthi ukuthinta kanjani, ngoba ungabangela ukozela, isiyezi, nombono ongacacile. Le miphumela ingaphazamisa ikhono lakho lokushayela ngokuphepha.

Abantu abaningi bathola ukuthi le miphumela emibi imnene futhi iyathuthuka ngemva kwemithamo embalwa yokuqala, kodwa wonke umuntu usabela ngendlela ehlukile. Abanye abantu bangase babe sensitive kakhulu kule miphumela kunabanye.

Uma kufanele ushayele, linda uze uthathe imithamo embalwa futhi uqiniseke ukuthi awuzizwa ukozela okukhulu noma isiyezi. Uma ungabaza, lungiselela ezinye izindlela zokuthutha kuze kube yilapho uqiniseka ukuthi umuthi awuthinti ikhono lakho lokushayela ngokuphepha.