Yini i-Dobutamine ne-Dextrose: Ukusetshenziswa, Umthamo, Imiphumela Eceleni nokuningi

I-Dobutamine ne-dextrose kuyinhlanganisela yemithi ekhethekile yomjovo esetshenziswa ezibhedlela ukusekela ukusebenza kwenhliziyo ezimweni eziphuthumayo. Le mithi enamandla yenhliziyo isiza inhliziyo yakho ukuba iphamphe ngempumelelo kuyilapho inikeza ushukela obalulekile wamandla lapho umzimba wakho udinga ukwesekwa okwengeziwe.

Ngokuvamile uzothola lo muthi esikhungweni sokunakekelwa okukhulu noma endaweni yokunakekelwa kwenhliziyo lapho ochwepheshe bezokwelapha bengaqapha eduze ukusabela kwenhliziyo yakho. Le nhlanganisela isebenza ngokuqinisa ukuncipha kwenhliziyo yakho ngenkathi iqinisekisa ukuthi umzimba wakho unamazinga afanele e-glucose ngesikhathi sokwelashwa.

Yini i-Dobutamine ne-Dextrose?

I-Dobutamine ne-dextrose ihlanganisa izingxenye ezimbili ezibalulekile ezisebenza ndawonye ukusekela uhlelo lwakho lwe-cardiovascular. I-Dobutamine ngumuthi wokwenziwa olingisa amakhemikhali emvelo emzimbeni wakho abizwa ngokuthi ama-catecholamines, asiza inhliziyo yakho ukuba ishaye ngokuqinile nangempumelelo.

Ingxenye ye-dextrose iyindlela ye-glucose (ushukela) enikeza amandla ngokushesha emangqamuzaneni omzimba wakho. Uma ihlanganisiwe, le mithi idala ikhambi elinganikezwa ngemithambo yakho ukusiza ukuzinzisa ukusebenza kwenhliziyo yakho ngenkathi kugcinwa amazinga kashukela egazi afanele.

Lo muthi uhlala ulungiswa futhi unikezwe ochwepheshe bezempilo ezindaweni zokwelapha ezilawulwayo. Ngeke uhlangane nale nhlanganisela ngaphandle kwezibhedlela noma izikhungo zezokwelapha ezikhethekile ngoba idinga ukuqapha okuqhubekayo nokulinganisa okunembile.

Yini i-Dobutamine ne-Dextrose Esetshenziselwa Yona?

Le nhlanganisela yemithi isetshenziswa ikakhulukazi ukwelapha ukuhluleka kwenhliziyo okukhulu nokushaqeka kwe-cardiogenic, izimo lapho inhliziyo yakho ingakwazi ukuphampa igazi ngokwanele ukuhlangabezana nezidingo zomzimba wakho. Odokotela ngokuvamile bayala lokhu lapho ezinye izindlela zokwelapha zingazange zinikeze ukuthuthuka okwanele ekusebenzeni kwenhliziyo.

Iqembu lakho lezokwelapha lingase lisebenzise le nhlanganisela ezimweni eziningi eziyinselele ezidinga ukusekelwa kwenhliziyo ngokushesha:

• Izigameko zokwehluleka kwenhliziyo okungazelelwe lapho inhliziyo yakho ingakwazi khona ukuphampa ngokwanele
• Ukushaqeka kwe-cardiogenic ngemva kokuhlaselwa yinhliziyo lapho umfutho wegazi wehla ngendlela eyingozi
• Ukusekelwa ngemva kokuhlinzwa kwenhliziyo ukusiza inhliziyo yakho ukuthi ilulame ekucindezelekeni kokuhlinzwa
• Isifo esibi semisipha yenhliziyo (i-cardiomyopathy) ngesikhathi sezigameko ezingazelelwe
• Izigameko zokwenqatshwa kokufakelwa kwenhliziyo lapho inhliziyo entsha idinga ukusekelwa okwengeziwe

Ezimweni ezingavamile, odokotela bangase futhi basebenzise le nhlanganisela ukuze benze ukuhlolwa kwenhliziyo okubizwa ngokuthi i-dobutamine stress echocardiography. Lokhu kusiza ukuhlola ukuthi inhliziyo yakho isebenza kahle kangakanani ngaphansi kokucindezeleka okulawulwayo lapho ukuhlolwa kokuzivocavoca kwendabuko kungenzeki.

Isebenza Kanjani I-Dobutamine ne-Dextrose?

Lokhu kuthathwa njengomuthi onamandla, osebenza ngokushesha wenhliziyo othinta ngokuqondile ikhono lenhliziyo yakho lokuzihudula nokuphampa igazi. I-Dobutamine isebenza ngokuvuselela ama-receptors athile emsipheni wenhliziyo yakho abizwa ngokuthi ama-beta-1 receptors, afana nokushintsha okutshela inhliziyo yakho ukuthi ishaye ngamandla.

Lapho i-dobutamine isebenzisa lawa ma-receptors, imisipha yenhliziyo yakho iyazihudula ngamandla, okwandisa inani legazi eliphampwa ngokuqina kwenhliziyo ngakunye. Lesi senzo sokumpompa esithuthukisiwe sisiza ukuletha umoya-mpilo kanye nezakhamzimba ngempumelelo emzimbeni wakho wonke, sisekela izitho ezibalulekile njengobuchopho bakho, izinso, nezinye izicubu.

Ingxenye ye-dextrose isebenza njengomthombo wamandla osheshayo wamaseli omzimba wakho, okubaluleke kakhulu lapho inhliziyo yakho isebenza kanzima. Umzimba wakho ungashintsha ngokushesha le glucose ibe amandla, usekela kokubili ukusebenza kwenhliziyo kanye nokusebenza komzimba wonke ngalesi sikhathi esibucayi.

Ngokungafani neminye imithi yenhliziyo ethinta ikakhulukazi izinga lokushaya kwenhliziyo, i-dobutamine igxila ekuthuthukiseni amandla okushaya kwenhliziyo ngakunye. Lokhu kuyenza ibaluleke kakhulu uma inhliziyo yakho idinga ukumpompa ngempumelelo enkulu kunokumane isheshe.

Ngingayithatha kanjani i-Dobutamine ne-Dextrose?

Awukwazi ukuthatha lo muthi ngomlomo noma ekhaya - unikezwa kuphela ngomugqa we-intravenous endaweni yasesibhedlela. Ochwepheshe bezempilo bazofaka ishubhu elincane emthanjeni wakho, ngokuvamile engalweni yakho noma esandleni, lapho umuthi ugeleza khona ngokuqhubekayo.

Umuthi uza njengesixazululo esixutshwe ngaphambilini esilungiswe ngokucophelela ngosokhemisi basemtholampilo noma abasebenzi bezokwelapha abaqeqeshiwe. Abahlengikazi bakho bazoxhuma lesi sixazululo ku-IV pump elawula ngqo ukuthi ungakanani umuthi owutholayo njalo ngomzuzu, okuqinisekisa ukulinganisa okunembile ngokuya ngempendulo yomzimba wakho.

Akudingeki ukhathazeke ngokudla noma ukuphuza noma yini ethile ngaphambi kokuthola lo muthi. Kodwa-ke, ithimba lakho lezokwelapha cishe lizogada amazinga kashukela egazini lakho njalo ngoba ingxenye ye-dextrose ingathinta amazinga e-glucose egazini lakho.

Abahlinzeki bakho bezempilo bazoqhubeka nokugada isigqi senhliziyo yakho, umfutho wegazi, nezinye izimpawu ezibalulekile ngaso sonke isikhathi sokwelashwa. Bazolungisa umthamo womuthi ngokuya ngendlela inhliziyo yakho esabela ngayo, ngezinye izikhathi benyusa noma behlisa inani ukuze kuzuzwe umphumela ongcono kakhulu.

Kufanele ngiyithathe isikhathi esingakanani i-Dobutamine ne-Dextrose?

Ubude besikhathi sokwelashwa buhlukahluka kakhulu ngokuya ngesimo sakho esithile nokuthi inhliziyo yakho isabela ngokushesha kangakanani emuthini. Iziguli eziningi zithola le nhlanganisela noma yikuphi kusuka emahoreni ambalwa kuya ezinsukwini ezimbalwa, kuye ngobunzima besimo senhliziyo yazo.

Iqembu lakho lezokwelapha lizoqhubeka nokuhlola ukusebenza kwenhliziyo yakho ngokusebenzisa amathuluzi ahlukahlukene okuqapha njengama-electrocardiograms (ECGs) kanye nama-echocardiograms. Uma inhliziyo yakho ibonisa ukuthuthuka okuqhubekayo futhi ikwazi ukuzigcina isebenza ngokwanele yona, bazokwehlisa kancane kancane umthamo womuthi.

Inqubo yokuyeka yenzeka kancane futhi ngokucophelela ukuvimbela inhliziyo yakho ukuthi inganciki ekusekelweni komuthi. Odokotela bakho ngokuvamile bazokushintshela emithini yenhliziyo yomlomo ongayithatha ekhaya ngaphambi kokuyeka ngokuphelele ukwelashwa kwe-IV.

Kwezinye izimo, iziguli ezinokuhluleka kwenhliziyo okungamahlalakhona okukhulu zingase zidinge ukwelashwa ngezikhathi ezithile ngale nhlanganisela ngesikhathi sokuhlala esibhedlela. Udokotela wakho wenhliziyo uzonquma uhlelo lokwelashwa olufanele kakhulu olusekelwe esimweni sakho senhliziyo kanye nokuphendula ekwelashweni.

Yini Imiphumela Eceleni ye-Dobutamine ne-Dextrose?

Njengayo yonke imithi enamandla, i-dobutamine ne-dextrose kungabangela imiphumela emibi, nakuba iziguli eziningi zikubekezelela kahle ngaphansi kokuqashwa kwezokwelapha okucophelelayo. Ithimba lakho lezempilo likuqapha eduze ikakhulu ukuze libheke futhi liphathe noma yiziphi izindlela ezingezinhle ezingase zenzeke.

Imiphumela emibi evamile ongase uyithole ihlanganisa lezi zimpawu ezilawulekayo ezivame ukuxazulula njengoba umzimba wakho uzivumela:

• Ukushaya kwenhliziyo okwandayo noma ukushaya kwenhliziyo njengoba inhliziyo yakho isabela emuthini
• Ikhanda elincane ngenxa yezinguquko ekuhambeni kwegazi nomfutho
• Isicanucanu esincane noma ukuqina kwesisu
• Umuzwa wokufudumala noma ukukhukhula ebusweni nasentanyeni yakho
• Ukukhathazeka okuncane noma ukungazinzi ngenxa yemiphumela ekhuthazayo
• Ukuthuthumela okuncane noma ukuzamazama ezandleni zakho

Le miphumela evamile ngokuvamile ibonisa ukuthi umuthi uyasebenza futhi ngokuvamile iba ngaphansi kokuqashelwa njengoba ukwelashwa kuqhubeka. Ithimba lakho lezokwelapha lilindele lezi zindlela futhi linamasu okukusiza ukuthi uzizwe ukhululekile.

Imiphumela emibi kakhulu idinga ukunakekelwa kwezempilo ngokushesha, nakuba ingavamile uma uqashwe kahle:

• Ushintsho oluyingozi lwesigqi senhliziyo (i-arrhythmias) olungase luthinte ukusebenza kwenhliziyo
• Umfutho wegazi ophezulu kakhulu ongase uqhubekisele phambili uhlelo lwakho lwe-cardiovascular
• Ubuhlungu besifuba noma ukwanda kwezimpawu zokuhluleka kwenhliziyo
• Ushintsho olukhulu lukashukela egazini oludinga ukulungiswa kwe-insulin
• Ukuphendula okukhulu komzimba okuhlanganisa ubunzima bokuphefumula noma ukuvuvukala

Izinkinga ezingavamile kodwa ezinzima zingahlanganisa ukulimala kwezicubu endaweni ye-IV uma umuthi uvuza ngaphandle komthambo, noma ukwehla okuyingozi komfutho wegazi uma kumiswa ngokushesha kakhulu. Ithimba lakho lezokwelapha lithatha izinyathelo ezithile zokuvimbela lezi zinkinga ngokubheka ngokucophelela kanye nezindlela ezifanele zokuphatha.

Ubani Ongafanele Athathe I-Dobutamine ne-Dextrose?

Izimo ezithile zezokwelapha zenza lo muthi ungafaneleki noma uyingozi, ngakho odokotela bakho bazobuyekeza ngokucophelela umlando wakho wezokwelapha ngaphambi kokuqala ukwelashwa. Uma unezinkinga ezithile zesigqi senhliziyo noma ezinye izimo zenhliziyo, ukwelashwa okuhlukile kungase kube izinketho eziphephe kakhulu.

Ithimba lakho lezokwelapha lizogwema lo muthi uma unezimo ezithile ezingenza ukwelashwa kube yingozi:

• I-aortic stenosis enkulu (ukuncipha kwe-valve enkulu yenhliziyo) okungase kube kubi ngokwanda kokuncipha kwenhliziyo
• I-Hypertrophic cardiomyopathy enokuvaleka, lapho ukuncipha kwenhliziyo okuqinile kungase kuvimbele ukugeleza kwegazi
• Izigqi zenhliziyo eziyingozi ezingalawuleki ezingase zibe yingozi ekuphileni
• Umfutho wegazi ophezulu ongagxilile ongase ufinyelele emazingeni ayingozi
• Ukungezwani okwaziwayo ne-dobutamine noma imithi efanayo
• Isifo sikashukela esibi esinzima ukusilawula, njengoba i-dextrose ingase yenze kube nzima ukuphatha ushukela wegazi

Izimo ezingavamile ezithile zidinga ukucatshangelwa ngokucophelela okukhulu kanye nokuqapha okukhethekile uma lo muthi udingeka. Lokhu kuhlanganisa i-pheochromocytoma (ithumba elingavamile le-adrenal gland), izifo ezinzima ze-thyroid, noma ukuhlaselwa yinhliziyo kwakamuva okunezinkinga ezithile.

Odokotela bakho bazohlola izinzuzo ezingaba khona ngokumelene nezingozi zesimo ngasinye somuntu ngamunye. Ngezinye izikhathi izinzuzo ezisindisa impilo zidlula izingozi, ngisho nasezigulini ezinokuphikisana okuhlobene, kodwa lokhu kudinga ukuqapha okukhulu nokunakekelwa okukhethekile.

Amagama Omkhiqizo we-Dobutamine ne-Dextrose

Le nhlanganisela yomuthi ivamise ukulungiswa njengengxube ethile yesibhedlela kunokuba itholakale njengomkhiqizo owodwa onegama lomkhiqizo. Izikhungo eziningi zezokwelapha zenza le nhlanganisela zisebenzisa izixazululo ezihlukene ze-dobutamine ne-dextrose ezixutshwe ngokuvumelana nemithetho ejwayelekile.

I-Dobutamine ngokwayo itholakala ngaphansi kwamagama omkhiqizo afana ne-Dobutrex, nakuba izibhedlela eziningi zisebenzisa izinguqulo ezivamile ezisebenza ngendlela efanayo. Ingxenye ye-dextrose iyisixazululo se-glucose esijwayelekile esisezingeni lezokwelapha esitholakala kabanzi kubakhiqizi abahlukahlukene bemithi.

I-pharmacy yesibhedlela sakho izolungisa ukugxilisa okuthile kanye nenhlanganisela ukuthi udokotela wakho u-oda ngokuya ngezidingo zakho ngazinye. Le ndlela eyenziwe ngendlela oyifisayo ivumela ukulinganisa okunembile futhi iqinisekisa ukuthi uthola ngqo lokho isimo senhliziyo yakho esikudingayo.

Ezinye izindlela ze-Dobutamine ne-Dextrose

Imithi eminingi ehlukile ingasekela ukusebenza kwenhliziyo, nakuba ngamunye esebenza ngendlela ehlukile futhi ivumelana nezimo ezihlukene. Udokotela wakho wenhliziyo uzokhetha inketho efanele kakhulu ngokusekelwe esimweni sakho senhliziyo esithile, ezinye izici zempilo, nokuthi usabela kahle kangakanani ekwelashweni.

Eminye imithi ye-IV engasiza ekusekeleni ukusebenza kwenhliziyo ihlanganisa lezi zinketho ezingase zicatshangelwe ithimba lakho lezokwelapha:

• I-Dopamine, ethinta kokubili ukusebenza kwenhliziyo nomfutho wegazi kodwa ingase ikhulise izinga lokushaya kwenhliziyo kakhulu
• I-Milrinone, esiza inhliziyo ukuthi ihlangane kangcono futhi iphumulele imithambo yegazi
• I-Norepinephrine, esetshenziswa ikakhulukazi lapho ukusekelwa komfutho wegazi kuyisidingo esikhulu
• I-Epinephrine, egcinelwe izimo eziphuthumayo ezidinga ukusekelwa kwenhliziyo nomfutho wegazi ngokushesha
• I-Levosimendan, umuthi omusha oqinisa ukuhlangana kwenhliziyo ngenkathi uvikela imisipha yenhliziyo

Ezinye izindlela ezingezona imithi zingabandakanya amadivaysi okusekela inhliziyo ngomshini ezimweni ezinzima. Lokhu kungahluka kusuka kumaphampu ebhola lesikhashana asiza inhliziyo yakho ukuthi ipompe igazi kuya kumadivaysi athuthukisiwe athatha ingxenye noma ngokuphelele ukusebenza kwenhliziyo ngesikhathi sokululama.

Uhlelo lwakho lokwelashwa lungahlanganisa izindlela eziningana, luqale ngemithi bese lwengeza ukusekelwa ngomshini uma kudingeka. Umgomo uhlala ukusekela inhliziyo yakho ngenkathi ilulama noma ukuzinzisa isimo sakho ukuze kulawulwe isikhathi eside.

Ingabe i-Dobutamine ne-Dextrose zingcono kune-Dopamine?

Yomibili imithi inezindima ezibalulekile ekunakekelweni kwenhliziyo, kodwa isebenza ngendlela ehlukile futhi ihamba phambili ezimweni ezihlukene. I-Dobutamine iqinisela ukuhlangana kwenhliziyo ngaphandle kokuthinta kakhulu umfutho wegazi, okwenza ilungele uma inhliziyo yakho idinga usizo lokupompa kodwa umfutho wegazi wakho uzinzile.

I-Dopamine inezinhlobonhlobo zemiphumela ngokuya ngomthamo osetshenzisiwe. Ngemithamo ephansi, ingathuthukisa ukusebenza kwezinso nokugeleza kwegazi, ngenkathi imithamo ephezulu ikhulisa amandla enhliziyo nomfutho wegazi. Lokhu kwenza i-dopamine iguquguquke kakhulu kodwa futhi kungenzeka ukuthi ibangele imiphumela emibi efana nokwanda kwenani lokushaya kwenhliziyo.

Iqembu lakho lezokwelapha likhetha phakathi kwale mithi ngokusekelwe ezidingweni zakho ezithile. Uma imisipha yenhliziyo yakho ibuthakathaka kodwa umfutho wegazi lakho wamukelekile, i-dobutamine ingase ibe yindlela engcono. Uma udinga ukusekelwa kwenhliziyo nokuthuthukiswa komfutho wegazi, i-dopamine ingase ifaneleke kakhulu.

Ucwaningo luphakamisa ukuthi i-dobutamine ingase ibe mnene ohlelweni lukagesi lwenhliziyo yakho, okungenzeka ukuthi idale izinkinga ezimbalwa eziyingozi zokushaya kwenhliziyo. Kodwa-ke, yomibili le mithi idinga ukuqapha okucophelelayo nokuphathwa kwezokwelapha okune-skill ukuqinisekisa ukwelashwa okuphephile nokuphumelelayo.

Imibuzo Evame Ukubuzwa Mayelana ne-Dobutamine ne-Dextrose

Ingabe i-Dobutamine ne-Dextrose Kuphephile Kubantu Abanesifo Sikashukela?

Lo muthi ungasetshenziswa ngokuphepha kubantu abanesifo sikashukela, kodwa udinga ukuqapha nokulawulwa koshukela wegazi okucophelelayo. Ingxenye ye-dextrose izokhuphula amazinga akho kashukela wegazi, ngakho-ke iqembu lakho lezokwelapha lizohlola ushukela wakho wegazi njalo futhi lilungise i-insulin noma eminye imithi yesifo sikashukela njengoba kudingeka.

Odokotela bakho bazosebenza ngokubambisana nochwepheshe besifo sikashukela uma kudingeka ukuze bagcine amazinga kashukela wegazi aphephile ngaso sonke isikhathi sokwelashwa. Bangase basebenzise ukuqapha okuqhubekayo kwe-glucose noma izivivinyo zegazi ezivamile ukuqinisekisa ukuthi isifo sakho sikashukela siqhubeka silawulwa kahle ngenkathi wamukela lo muthi wenhliziyo.

Ngingenzani Uma Ngithola Ngengozi I-Dobutamine ne-Dextrose Eningi Kakhulu?

Njengoba lo muthi unikezwa kuphela ezindaweni zezibhedlela ezinokuqapha okuqhubekayo, ukweqisa ngengozi akuvamile kakhulu futhi kutholwa ngokushesha yiqembu lakho lezokwelapha. Uma umuthi omningi ngokweqile unikezwa ngengozi, abahlinzeki bakho bezempilo bazobona izimpawu ngokushesha ngokusebenzisa ukuqapha ukushaya kwenhliziyo nezinguquko zezimpawu ezibalulekile.

Ukwelashwa kokweqisa kuhlanganisa ukuyeka ngokushesha noma ukunciphisa umthamo womuthi nokuhlinzeka ngokunakekelwa okusekelayo. Ithimba lakho lezokwelapha liqeqeshwe ukubhekana nalezi zimo futhi linama-protocol athile okuguqula noma yimiphi imiphumela emibi ngokuphepha nangokushesha.

Ngingenzani Uma Ngiphuthelwa Umthamo We-Dobutamine kanye ne-Dextrose?

Ukuphuthelwa imithamo ngokuvamile akuyona into ekhathazayo njengoba lo muthi unikezwa njengokufakwa kwe-IV okuqhubekayo ezindaweni zase-hospital. Abahlengikazi bakho baqapha ipompo le-IV ngokuqhubekayo ukuqinisekisa ukulethwa okuqhubekayo, futhi noma yikuphi ukuphazamiseka kulungiswa ngokushesha ngabasebenzi bezokwelapha.

Uma kwenzeka izinkinga zobuchwepheshe ngepompo le-IV noma umugqa, ithimba lakho lezokwelapha lizokwenza ngokushesha ukuthi umuthi uqalwe kabusha noma lishintshele kwezinye izindlela zokusekela. Baqeqeshwe ukugcina ukusekelwa kwenhliziyo okuqhubekayo ngaphandle kwezikhala eziyingozi ekwelashweni.

Ngingayeka nini Ukuthatha I-Dobutamine kanye ne-Dextrose?

Ithimba lakho lezokwelapha lizinquma ukuthi lingayeka nini lo muthi ngokusekelwe ekuthuthukisweni kwenhliziyo yakho kanye nekhono lokusebenza ngokwanele ngaphandle kokusekelwa. Lesi sinqumo sihlanganisa ukuhlolwa ngokucophelela kokusebenza kwenhliziyo yakho ngokusebenzisa izivivinyo ezihlukahlukene kanye nokuqapha ukusabela kwakho ekunciphiseni umthamo kancane kancane.

Inqubo yokuyeka ngokuvamile yenzeka kancane kancane emahoreni noma ezinsukwini, ivumela inhliziyo yakho ukuthi ijwayele kancane ukusebenza ngaphandle kokusekelwa komuthi. Odokotela bakho bazoqinisekisa ukuthi inhliziyo yakho ihlala izinzile ngaphambi kokuyeka ngokuphelele ukwelashwa futhi bakushintshele emithini yomlomo uma kudingeka.

Ngingashayela Noma Ngisebenze Ngemva Kokuthola I-Dobutamine kanye ne-Dextrose?

Ngeke ukwazi ukushayela noma ukusebenza ngenkathi uthola lo muthi njengoba unikezwa kuphela ezindaweni zase-hospital lapho udinga khona ukuqapha okuqhubekayo kwezokwelapha. Ngemva kokuthi ukwelashwa kuphela futhi ukhishwe esibhedlela, udokotela wakho uzokweluleka ngokuthi kuphephile nini ukuqala kabusha imisebenzi evamile.

Isikhathi sokululama siyahlukahluka kuye ngesimo senhliziyo yakho esingaphansi kanye nempilo yonke. Udokotela wakho wenhliziyo uzohlinzeka ngesiqondiso esithile mayelana nokubuyela emsebenzini, ukushayela, neminye imisebenzi ngokusekelwe esimweni sakho ngasinye kanye nokuthuthuka kokusebenza kwenhliziyo.